Stem cell antigen-1 positive cell-based systemic human growth hormone gene transfer strategy increases endosteal bone resorption and bone loss in mice

Journal of Gene Medicine

Volumn 13, Issue 2, 2011, Pages 77-88

  Hall, Susan L ^a,b   Chen, Shin Tai ^a,b   Wergedal, Jon E ^a,b   Gridley, Daila S ^b   Mohan, Subburaman ^a,b   Lau, K H William ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bone resorption; Gene therapy; Growth hormone; IGF I; Marrow transplantation; Sca 1; Stem cell

Indexed keywords

BETA GALACTOSIDASE; HUMAN GROWTH HORMONE; LENTIVIRUS VECTOR; MESSENGER RNA; SOMATOMEDIN C; STEM CELL ANTIGEN 1;

ARTICLE; BONE DENSITY; BONE MARROW CELL; BONE MASS; BONE REMODELING; CONTROLLED STUDY; EX VIVO STUDY; FEMUR; GENE EXPRESSION; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; POINT MUTATION; PRIORITY JOURNAL; RECIPIENT; TRABECULAR BONE; TRANSGENIC MOUSE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; ANTIGENS, LY; BONE AND BONES; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; BONE RESORPTION; FEMUR; GENE DOSAGE; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HEK293 CELLS; HUMAN GROWTH HORMONE; HUMANS; LENTIVIRUS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RNA, MESSENGER; TRANSDUCTION, GENETIC; WHOLE-BODY IRRADIATION;

MUS; MUS MUSCULUS;

EID: 79952679769     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1542     Document Type: Article

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