Theory and simulation on the kinetics of protein-ligand binding coupled to conformational change

Journal of Chemical Physics

Volumn 134, Issue 10, 2011, Pages

  Cai, Lu ^a   Zhou, Huan Xiang ^b  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b FLORIDA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL RESULTS; BINDING MECHANISMS; BINDING RATE CONSTANTS; BROWNIAN DYNAMICS SIMULATIONS; CONFORMATIONAL CHANGE; CONFORMATIONAL SELECTION; CONFORMATIONAL SPACE; CONFORMATIONAL TRANSITIONS; ENERGY SURFACE; GENERAL MODEL; INDUCED FIT; LIGAND BINDING; LOW COSTS; LOWER AND UPPER BOUNDS; REACTIVE CONFORMATION; SIMULATION RESULT; TIGHT BOUND; TRANSITION RATES;

BROWNIAN MOVEMENT; COMPUTER SIMULATION; CONFORMATIONS; LIGANDS; PROTEINS; RATE CONSTANTS;

BINDING ENERGY;

LIGAND; PROTEIN;

ARTICLE; CHEMISTRY; COMPUTER SIMULATION; KINETICS; PROTEIN BINDING; PROTEIN CONFORMATION;

COMPUTER SIMULATION; KINETICS; LIGANDS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS;

EID: 79952649532     PISSN: 00219606     EISSN: None     Source Type: Journal    
DOI: 10.1063/1.3561694     Document Type: Article

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