The S3 guidelines of the German Society of Digestive and Metabolic Diseases (DGVS) and the German Society for Neurogastroenterology and Motility (DGNM) on the definition, pathophysiology, diagnosis and treatment of intestinal dysmotility - AWMF Registry Number: 021/018;S3-Leitlinie der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Neurogastroenterologie und Motilität (DGNM) zu Definition, Pathophysiologie, Diagnostik und Therapie intestinaler Motilitätsstö rungen 1

Zeitschrift fur Gastroenterologie

Volumn 49, Issue 3, 2011, Pages 374-390

  Keller, J ^a   Wedel, T ^b   Seidl, H ^c   Kreis, M E ^d   Andresen, V ^a   Preiss J C ^e   Layer, P ^a   Van Der Voort, I ^e  

^a ISRAELITISCHES KRANKENHAUS   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c Chirurgische Klinik Munchen Bogenhausen   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GASTROINTESTINAL DISEASE; GERMANY; INTESTINAL DYSMOTILITY; METABOLIC DISORDER; PATHOPHYSIOLOGY; PRACTICE GUIDELINE;

EID: 79952638274     PISSN: 00442771     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0029-1245993     Document Type: Article

References (106)

1. Layer P. S3-Leitlinie der DGVS und DGNM zur Definition, Pathophysiologie, Diagnostik und Therapie des Reizdarmsyndroms. zur Einreichung bei Z Gastroenterol
2. Fachgesellschaften ÄZQAdWM ed. Deutsches Instrument zur methodischen Leitlinien-Bewertung (DELBI) - Fassung 2005 / 2006 + Domäne 8. Berlin 2008
3. Phillips B, Ball C, Sackett D et al. Oxford-Centre for Evidence-Based Medicine - Levels of Evidence and Grades of Recommendation. 2001
4. Kunz R, Burnand B, Schunemann H J. Das GRADE System. Internist 2008 49 673-680
5. Connor F L., Di Lorenzo C. Chronic intestinal pseudo-obstruction: assessment and management. Gastroenterology 2006 130 S29-S36 (Pubitemid 43208857)
6. Stanghellini V, Cogliandro R F., Giorgio R de et al. Chronic intestinal pseudo-obstruction: manifestations, natural history and management. Neurogastroenterol Motil 2007 19 440-452 (Pubitemid 46905392)
7. Seidl H, Pehl C, Schepp W et al. Chronische intestinale Pseudoobstruktion-Übersicht und Update 2008. Z Gastroenterol 2008 46 704-711
8. Kessmann J. Hirschsprung's disease: diagnosis and management. Am Fam Physician 2006 74 1319-1322 (Pubitemid 44607305)
9. Furness J B. The enteric nervous system: normal functions and enteric neuropathies. Neurogastroenterol Motil 2008 20 (Suppl 1) 32-38 (Pubitemid 351514528)
10. Knowles C H., De Giorgio R, Kapur R P. et al. The London Classification of gastrointestinal neuromuscular pathology: report on behalf of the Gastro 2009 International Working Group. Gut 2010 59 882-887
11. Goyal R K., Hirano I. The enteric nervous system. N Engl J Med 1996 334 1106-1115 (Pubitemid 26120190)
12. Collins S M. The immunomodulation of enteric neuromuscular function: implications for motility and inflammatory disorders. Gastroenterology 1996 111 1683-1699 (Pubitemid 26404236)
13. Wood J D. Intrinsic neural control of intestinal motility. Annu Rev Physiol 1981 43 33-51
14. De Giorgio R, Camilleri M. Human enteric neuropathies: morphology and molecular pathology. Neurogastroenterol Motil 2004 16 515-531 (Pubitemid 39472185)
15. Di Lorenzo C. Pseudo-obstruction: current approaches. Gastroenterology 1999 116 980-987 (Pubitemid 29153547)
16. De Giorgio R, Guerrini S, Barbara G et al. New insights into human enteric neuropathies. Neurogastroenterol Motil 2004 16 (Suppl 1) 143-147 (Pubitemid 38580957)
17. De Giorgio R, Seri M, Cogliandro R et al. Analysis of candidate genes for intrinsic neuropathy in a family with chronic idiopathic intestinal pseudo-obstruction. Clin Genet 2001 59 131-133 (Pubitemid 32220028)
18. Deglincerti A, De Giorgio R, Cefle K et al. A novel locus for syndromic chronic idiopathic intestinal pseudo-obstruction maps to chromosome 8q23-q24. Eur J Hum Genet 2007 15 889-897 (Pubitemid 47109050)
19. Gargiulo A, Auricchio R, Barone M V. et al. Filamin A is mutated in X-linked chronic idiopathic intestinal pseudo-obstruction with central nervous system involvement. Am J Hum Genet 2007 80 751-758 (Pubitemid 46564411)
20. Finsterer J. Overview on visceral manifestations of mitochondrial disorders. Neth J Med 2006 64 61-71
21. Heanue T A., Pachnis V. Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies. Nat Rev Neurosci 2007 8 466-479 (Pubitemid 46789228)
22. De Giorgio R, Guerrini S, Barbara G et al. Inflammatory neuropathies of the enteric nervous system. Gastroenterology 2004 126 1872-1883 (Pubitemid 38736352)
23. Smith V V., Gregson N, Foggensteiner L et al. Acquired intestinal aganglionosis and circulating autoantibodies without neoplasia or other neural involvement. Gastroenterology 1997 112 1366-1371 (Pubitemid 27157551)
24. Di Nardo G, Blandizzi C, Volta U et al. Review article: molecular, pathological and therapeutic features of human enteric neuropathies. Aliment Pharmacol Ther 2008 28 25-42 (Pubitemid 351782813)
25. Knowles C H., De Giorgio R, Kapur R P. et al. Gastrointestinal neuromuscular pathology: guidelines for histological techniques and reporting on behalf of the Gastro 2009 International Working Group. Acta Neuropathol 2009 118 271-301
26. Koh S, Bradley R F., French S W. et al. Congenital visceral myopathy with a predominantly hypertrophic pattern treated by multivisceral transplantation. Hum Pathol 2008 39 970-974
27. Dewit S, Hertogh G de, Geboes K et al. Chronic intestinal pseudo-obstruction caused by an intestinal inflammatory myopathy: case report and review of the literature. Neurogastroenterol Motil 2008 20 343-348 (Pubitemid 351441726)
28. Bassotti G, Villanacci V, Fisogni S et al. Enteric glial cells and their role in gastrointestinal motor abnormalities: introducing the neuro-gliopathies. World J Gastroenterol 2007 13 4035-4041 (Pubitemid 47323154)
29. Ruhl A. Glial cells in the gut. Neurogastroenterol Motil 2005 17 777-790 (Pubitemid 41746516)
30. Bush T G. Enteric glial cells. An upstream target for induction of necrotizing enterocolitis and Crohn's disease? Bioessays 2002 24 130-140 (Pubitemid 34179291)
31. Savidge T C., Sofroniew M V., Neunlist M. Starring roles for astroglia in barrier pathologies of gut and brain. Lab Invest 2007 87 731-736 (Pubitemid 47077264)
32. Bassotti G, Villanacci V, Maurer C A. et al. The role of glial cells and apoptosis of enteric neurones in the neuropathology of intractable slow transit constipation. Gut 2006 55 41-46 (Pubitemid 41820633)
33. Bassotti G, Villanacci V, Cathomas G et al. Enteric neuropathology of the terminal ileum in patients with intractable slow-transit constipation. Hum Pathol 2006 37 1252-1258 (Pubitemid 44404122)
34. Bassotti G, Villanacci V, Nascimbeni R et al. Colonic neuropathological aspects in patients with intractable constipation due to obstructed defecation. Mod Pathol 2007 20 367-374 (Pubitemid 46350685)
35. Dinning P G., Bampton P A., Andre J et al. Abnormal predefecatory colonic motor patterns define constipation in obstructed defecation. Gastroenterology 2004 127 49-56 (Pubitemid 38962273)
36. Iantorno G, Bassotti G, Kogan Z et al. The enteric nervous system in chagasic and idiopathic megacolon. Am J Surg Pathol 2007 31 460-468 (Pubitemid 46673121)
37. Cajal. Sur les ganglions et plexus nerveux d'intestin. C R Soc Biol 1893 5 217-223
38. Sarna S K. Are interstitial cells of Cajal plurifunction cells in the gut? Am J Physiol Gastrointest Liver Physiol 2008 294 G372-G390 (Pubitemid 351255512)
39. Sanders K M., Koh S D., Ward S M. Interstitial cells of cajal as pacemakers in the gastrointestinal tract. Annu Rev Physiol 2006 68 307-343
40. Knowles C H., De Giorgio R, Kapur R P. et al. Gastrointestinal neuromuscular pathology: guidelines for histological techniques and reporting on behalf of the Gastro 2009 International Working Group. Acta Neuropathol 2009 118 271-301
41. Huizinga J D., Lammers W J. Gut peristalsis is governed by a multitude of cooperating mechanisms. Am J Physiol Gastrointest Liver Physiol 2009 296 G1-G8
42. Yanagida H, Yanase H, Sanders K M. et al. Intestinal surgical resection disrupts electrical rhythmicity, neural responses, and interstitial cell networks. Gastroenterology 2004 127 1748-1759 (Pubitemid 39575854)
43. De Giorgio R, Sarnelli G, Corinaldesi R et al. Advances in our understanding of the pathology of chronic intestinal pseudo-obstruction. Gut 2004 53 1549-1552 (Pubitemid 39434089)
44. Smout A J. Recent developments in gastrointestinal motility. Scand J Gastroenterol Suppl 2006 243 25-31
45. Stanghellini V, Cogliandro R F., De Giorgio R et al. Natural history of chronic idiopathic intestinal pseudo-obstruction in adults: a single center study. Clin Gastroenterol Hepatol 2005 3 449-458 (Pubitemid 40616910)
46. Eisen G M., Baron T H., Dominitz J A. et al. Acute colonic pseudo-obstruction. Gastrointest Endosc 2002 56 789-792 (Pubitemid 36236704)
47. Saunders M D. Acute colonic pseudo-obstruction. Gastrointest Endosc Clin N Am 2007 17 341-360, vi-vii (Pubitemid 46860344)
48. Saunders M D., Kimmey M B. Systematic review: acute colonic pseudo-obstruction. Aliment Pharmacol Ther 2005 22 917-925 (Pubitemid 41634872)
49. Saunders M D. Acute colonic pseudo-obstruction. Best Pract Res Clin Gastroenterol 2007 21 671-687 (Pubitemid 47074361)
50. Vanek V W., Al-Salti M. Acute pseudo-obstruction of the colon (Ogilvie's syndrome). An analysis of 400 cases. Dis Colon Rectum 1986 29 203-210 (Pubitemid 16124078)
51. Gladman M A., Knowles C H. Novel concepts in the diagnosis, pathophysiology and management of idiopathic megabowel. Colorectal Dis 2008 10 531-538; discussion 538 - 540 (Pubitemid 351803057)
52. Bharucha A E. Constipation. Best Pract Res Clin Gastroenterol 2007 21 709-731 (Pubitemid 47074371)
53. Martucciello G. Hirschsprung's disease, one of the most difficult diagnoses in pediatric surgery: a review of the problems from clinical practice to the bench. Eur J Pediatr Surg 2008 18 140-149 (Pubitemid 351798845)
54. Longstreth G F., Thompson W G., Chey W D. et al. Functional bowel disorders. Gastroenterology 2006 130 1480-1491
55. Wong S W., Lubowski D Z. Slow-transit constipation: evaluation and treatment. ANZ J Surg 2007 77 320-328 (Pubitemid 46709704)
56. Bassotti G, Villanacci V. Slow transit constipation: a functional disorder becomes an enteric neuropathy. World J Gastroenterol 2006 12 4609-4613 (Pubitemid 44269716)
57. Rao S S. Constipation: evaluation and treatment of colonic and anorectal motility disorders. Gastroenterol Clin North Am 2007 36 687-711, x (Pubitemid 47575844)
58. Bassotti G, Stanghellini V, Chiarioni G et al. Upper gastrointestinal motor activity in patients with slow-transit constipation. Further evidence for an enteric neuropathy. Dig Dis Sci 1996 41 1999-2005 (Pubitemid 26366801)
59. Seidl H, Gundling F, Pehl C et al. Small bowel motility in functional chronic constipation. Neurogastroenterol Motil 2009 21 1278-e122
60. Glia A, Akerlund J E., Lindberg G. Outcome of colectomy for slow-transit constipation in relation to presence of small-bowel dysmotility. Dis Colon Rectum 2004 47 96-102 (Pubitemid 38040252)
61. Andromanakos N, Skandalakis P, Troupis T et al. Constipation of anorectal outlet obstruction: pathophysiology, evaluation and management. J Gastroenterol Hepatol 2006 21 638-646
62. Ouyang A, Locke G 3 rd R. Overview of neurogastroenterology- gastrointestinal motility and functional GI disorders: classification, prevalence, and epidemiology. Gastroenterol Clin North Am 2007 36 485-498, vii (Pubitemid 47575842)
63. Spiller R. Role of motility in chronic diarrhoea. Neurogastroenterol Motil 2006 18 1045-1055 (Pubitemid 44748268)
64. Camilleri M, Bharucha A E., Lorenzo C di et al. American Neurogastroenterology and Motility Society consensus statement on intraluminal measurement of gastrointestinal and colonic motility in clinical practice. Neurogastroenterol Motil 2008 20 1269-1282
65. Keller J, Franke A, Storr M et al. Klinisch relevante Atemtests in der gastroenterologischen Diagnostik - Empfehlungen der Deutschen Gesellschaft für Neurogastroenterologie und Motilität sowie der Deutschen Gesellschaft für Verdauungs- und Stoffwechselerkrankungen. Z Gastroenterol 2005 43 1071-1090 (Pubitemid 41360848)
66. Antonucci A, Fronzoni L, Cogliandro L et al. Chronic intestinal pseudo-obstruction. World J Gastroenterol 2008 14 2953-2961
67. Pehl C, Enck P, Franke A et al. Empfehlungen zur anorektalen Manometrie im Erwachsenenalter. Z Gastroenterol 2007 45 397-417 (Pubitemid 47055638)
68. Camilleri M. New imaging in neurogastroenterology: an overview. Neurogastroenterol Motil 2006 18 805-812 (Pubitemid 44201166)
69. Lorijn F de, Kremer L C., Reitsma J B. et al. Diagnostic tests in Hirschsprung disease: a systematic review. J Pediatr Gastroenterol Nutr 2006 42 496-505 (Pubitemid 43804726)
70. Rao S S., Ozturk R, Laine L. Clinical utility of diagnostic tests for constipation in adults: a systematic review. Am J Gastroenterol 2005 100 1605-1615 (Pubitemid 41032371)
71. American College of Gastroenterology Chronic Constipation Task Force. An evidence-based approach to the management of chronic constipation in North America. Am J Gastroenterol 2005 100 (Suppl 1) S1-S4
72. Keller J, Layer P. Intestinal and anorectal motility and functional disorders. Best Pract Res Clin Gastroenterol 2009 23 407-423
73. Ponec R J., Saunders M D., Kimmey M B. Neostigmine for the treatment of acute colonic pseudo-obstruction. N Engl J Med 1999 341 137-141 (Pubitemid 29325740)
74. Camilleri M, Kerstens R, Rykx A et al. A placebo-controlled trial of prucalopride for severe chronic constipation. N Engl J Med 2008 358 2344-2354 (Pubitemid 351749158)
75. Tack J, Outryve M van, Beyens G et al. Prucalopride (Resolor) in the treatment of severe chronic constipation in patients dissatisfied with laxatives. Gut 2009 58 357-365
76. Husebye E. The pathogenesis of gastrointestinal bacterial overgrowth. Chemotherapy 2005 51 (Suppl 1) 1-22 (Pubitemid 40663186)
77. Lloyd D A., Gabe S M. Managing liver dysfunction in parenteral nutrition. Proc Nutr Soc 2007 66 530-538
78. Sabate J M., Jouet P, Harnois F et al. High prevalence of small intestinal bacterial overgrowth in patients with morbid obesity: a contributor to severe hepatic steatosis. Obes Surg 2008 18 371-377
79. Grunkemeier D M., Cassara J E., Dalton C B. et al. The narcotic bowel syndrome: clinical features, pathophysiology, and management. Clin Gastroenterol Hepatol 2007 5 1126-1139; quiz 1121 - 1122 (Pubitemid 47488969)
80. Tuteja A K., Biskupiak J, Stoddard G J. et al. Opioid-induced bowel disorders and narcotic bowel syndrome in patients with chronic non-cancer pain. Neurogastroenterol Motil 2010 22 424-430, e96
81. Mehendale S R., Yuan C S. Opioid-induced gastrointestinal dysfunction. Dig Dis 2006 24 105-112
82. Panchal S J., Muller-Schwefe P, Wurzelmann J I. Opioid-induced bowel dysfunction: prevalence, pathophysiology and burden. Int J Clin Pract 2007 61 1181-1187 (Pubitemid 46934629)
83. Loftus C G., Harewood G C., Baron T H. Assessment of predictors of response to neostigmine for acute colonic pseudo-obstruction. Am J Gastroenterol 2002 97 3118-3122 (Pubitemid 35424584)
84. Wald A. Constipation in the primary care setting: current concepts and misconceptions. Am J Med 2006 119 736-739 (Pubitemid 44291632)
85. Ramkumar D, Rao S S. Efficacy and safety of traditional medical therapies for chronic constipation: systematic review. Am J Gastroenterol 2005 100 936-971 (Pubitemid 40592390)
86. Brandt L J., Prather C M., Quigley E M. et al. Systematic review on the management of chronic constipation in North America. Am J Gastroenterol 2005 100 (Suppl 1) S5-S21
87. Quartero A O., Meineche-Schmidt V, Muris J et al. Bulking agents, antispasmodic and antidepressant medication for the treatment of irriable bowel syndrome. Cochrane Database Syst Rev 2005 18 CD003460
88. Lederle F A., Busch D L., Mattox K M. et al. Cost-effective treatment of constipation in the elderly: a randomized double-blind comparison of sorbitol and lactulose. Am J Med 1990 89 597-601 (Pubitemid 20384316)
89. Muller-Lissner S A., Kamm M A., Scarpignato C et al. Myths and misconceptions about chronic constipation. Am J Gastroenterol 2005 100 232-242 (Pubitemid 41623292)
90. Mollenbrink M, Bruckschen E. Treatment of chronic constipation with physiologic Escherichia coli bacteria. Results of a clinical study of the effectiveness and tolerance of microbiological therapy with the E. coli Nissle 1917 strain (Mutaflor). Med Klin 1994 89 587-593 (Pubitemid 24353680)
91. Voderholzer W A., Schatke W, Muhldorfer B E. et al. Clinical response to dietary fiber treatment of chronic constipation. Am J Gastroenterol 1997 92 95-98 (Pubitemid 27027036)
92. Koh C E., Young C J., Young J M. et al. Systematic review of randomized controlled trials of the effectiveness of biofeedback for pelvic floor dysfunction. Br J Surg 2008 95 1079-1087
93. Enck P, Voort I van der, Klosterhalfen S. Biofeedback therapy in fecal incontence and constipation. Neurogastroenterol Motil 2009 21 1133-1141
94. Coran A G., Teitelbaum D H. Recent advances in the management of Hirschsprung's disease. Am J Surg 2000 180 382-387 (Pubitemid 32011323)
95. Weidner B C., Waldhausen J H. Swenson revisited: a one-stage, transanal pull-through procedure for Hirschsprung's disease. J Pediatr Surg 2003 38 1208-1211 (Pubitemid 37048043)
96. Rintala R J. Transanal coloanal pull-through with a short muscular cuff for classic Hirschsprung's disease. Eur J Pediatr Surg 2003 13 181-186 (Pubitemid 36999021)
97. Hadidi A. Transanal endorectal pull-through for Hirschsprung's disease: a comparison with the open technique. Eur J Pediatr Surg 2003 13 176-180 (Pubitemid 36999020)
98. Langer J C., Durrant A C., Torre L de la et al. One-stage transanal Soave pullthrough for Hirschsprung disease: a multicenter experience with 141 children. Ann Surg 2003 238 569-583; discussion 583 - 585
99. Tomita R, Ikeda T, Fujisaki S et al. Hirschsprung's disease and its allied disorders in adults' histological and clinical studies. Hepatogastroenterology 2003 50 1050-1053 (Pubitemid 36723840)
100. Hadidi A. Transanal endorectal pull-through for Hirschsprung's disease: experience with 68 patients. J Pediatr Surg 2003 38 1337-1340 (Pubitemid 37159084)
101. Saleh W, Rasheed K, Mohaidly M A. et al. Management of Hirschsprung's disease: a comparison of Soave's and Duhamel's pull-through methods. Pediatr Surg Int 2004 20 590-593 (Pubitemid 39350172)
102. Hyman P E. Adolescents and young adults with Hirschsprung's disease. Curr Gastroenterol Rep 2006 8 425-429 (Pubitemid 44515365)
103. Miyamoto M, Egami K, Maeda S et al. Hirschsprung's disease in adults: report of a case and review of the literature. J Nippon Med Sch 2005 72 113-120 (Pubitemid 40628620)
104. Nyam D C., Pemberton J H., Ilstrup D M. et al. Long-term results of surgery for chronic constipation. Dis Colon Rectum 1997 40 273-279 (Pubitemid 27120133)
105. Kamm M A., Hawley P R., Lennard-Jones J E. Outcome of colectomy for severe idiopathic constipation. Gut 1988 29 969-973
106. Ripetti V, Caputo D, Greco S et al. Is total colectomy the right choice in intractable slow-transit constipation? Surgery 2006 140 435-440