Benchmark dose approach for low-level lead induced haematogenesis inhibition and associations of childhood intelligences with ALAD activity and ALA levels

Science of the Total Environment

Volumn 409, Issue 10, 2011, Pages 1806-1810

  Wang, Q ^a   Ye, L X ^a   Zhao, H H ^b   Chen, J W ^a   Zhou, Y K ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b MINZU UNIVERSITY OF CHINA   (China)

Author keywords

Benchmark dose; Child; Haematogenesis; Intelligence; Lead

Indexed keywords

AMINOLEVULINIC ACID; BENCHMARK DOSE; BLOOD LEAD; CHILD; HAEMATOGENESIS; HAEMATOLOGICAL INDICES; INTELLIGENCE; LOWER BOUNDS; SENSITIVE INDICATOR; ZINC PROTOPORPHYRIN;

LEAD; PORPHYRINS;

BLOOD;

AMINOLEVULINIC ACID; COPROPORPHYRIN; LEAD; PORPHOBILINOGEN SYNTHASE; PROTOPORPHYRIN ZINC;

BENCHMARKING; BIOINDICATOR; CHILD HEALTH; CONCENTRATION (COMPOSITION); DOSE-RESPONSE RELATIONSHIP; HEALTH IMPACT; HEMATOLOGY; INHIBITION; LEAD; POLLUTION EFFECT; SENSITIVITY ANALYSIS;

ANALYTIC METHOD; ARTICLE; BENCHMARK DOSE APPROACH; BLOOD SAMPLING; BLOOD TOXICITY; CHILD; CHINA; CLINICAL INDICATOR; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; HEMATOPOIESIS; HUMAN; INTELLIGENCE QUOTIENT; LEAD BLOOD LEVEL; LEAD POISONING; MALE; MENTAL DETERIORATION; MENTAL DEVELOPMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUALITY CONTROL; RURAL AREA; SCHOOL CHILD; SEX DIFFERENCE; URINE LEVEL;

AMINOLEVULINIC ACID; BENCHMARKING; BIOLOGICAL MARKERS; CHILD; COPROPORPHYRINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FEMALE; HEMATOPOIESIS; HUMANS; INTELLIGENCE; LEAD; MALE; PORPHOBILINOGEN SYNTHASE; PROTOPORPHYRINS;

CHINA;

EID: 79952627359     PISSN: 00489697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2011.01.045     Document Type: Article

References (39)

1. Ahamed M., Verma S., Kumar A., MKJ S. Environmental exposure to lead and its correlation with biochemical indices in children. Sci Total Environ 2005, 346(1-3):48-55.
2. Bannon D.I., Abounader R., Lees P.S., Bressler J.P. Effect of DMT1 knockdown on iron, cadmium, and lead uptake in Caco-2 cells. Am J Physiol Cell Physiol 2003, 284(1):C44-C50.
3. Barbosa F., Tanus-Santo J.E., Gerlach R.F., Parsons P.J. A critical review of biomarkers used for monitoring human exposure to lead: advantages, limitations, and future needs. Environ Health Perspect 2005, 113(12):1669-1674.
4. Barnes D.G., Daston G.P., Evans J.S., Jarabek A.M., Kavlock R.J., Kimmel C.A., et al. Benchmark Dose Workshop: criteria for use of a benchmark dose to estimate a reference dose. Regul Toxicol Pharmacol 1995, 21(2):296-306.
5. Brown L.M., Kim D., Yomai A., Meyer P.A., Noonan G.P., Huff D., et al. Blood lead levels and risk factors for lead poisoning in children and caregivers in Chuuk State, Micronesia. Int J Hyg Environ Health 2005, 208(4):231-236.
6. Campagna D., Huel G., Girard F., Sahuquillo J., Blot P. Environmental lead exposure and activity of δ-aminolevulinic acid dehydratase (ALA-D) in maternal and cord blood. Toxicology 1999, 134(2-3):143-152.
7. Crump K.S. A new method for determining allowable daily intakes. Fundam Appl Toxicol 1984, 4(5):854-871.
8. University DoPoBN Raven's Standard Progressive Matrices Handbook 1988, Beijing Normal University Press, Beijing, 60 p.
9. EPA US The use of the benchmark dose approach in health risk assessment 1995, EPA/630/R-94/007.
10. EPA US BMDS Benchmark Dose Software 2001, For software background and tutorial see:. http://www.epa.gov/NCEA/bmds_training/index.htm.
11. Gunshin H., Mackenzie B., Berger U.V., Gunshin Y., Romero M.F., Boron W.F., et al. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 1997, 338(6641):482-488.
12. Heinze I., Gross R., Stehle P., Dillon D. Assessment of lead exposure in schoolchildren from Jakarta. Environ Health Perspect 1998, 106(8):499-501.
13. Hense H., Filipiak B., Novak L., Stoeppler M. Nonoccupational determinants of blood lead concentrations in a general population. Int J Epidemiol 1992, 21(4):753-762.
14. Hermes-Lima M., Valle V.G., Vercesi A.E., Bechara E.J. Damage to rat liver mitochondria promoted by delta-aminolevulinic acid-generated reactive oxygen species: connections with acute intermittent porphyria and lead-poisoning. Biochim Biophys Acta 1991, 1056(1):57-63.
15. Jusko T.A., Henderson C.R., Lanphear B.P., Cory-Slechta D.A., Parsons P.J., Canfield R.L. Blood lead concentrations <10microg/dL and child intelligence at 6years of age. Environ Health Perspect 2008, 116(2):243-248.
16. Kwong W.T., Friello P., Semba R.D. Interactions between iron deficiency and lead poisoning: epidemiology and pathogenesis. Sci Total Environ 2004, 330(1-3):21-37.
17. Labbe R.F., Vreman H.J., Stevenson D.K. Zinc protoporphyrin: a metabolite with a mission. Clin Chem 1999, 45(12):2060-2072.
18. Lanphear B.P., Hornung R., Khoury J., Yolton K., Baghurst P., Bellinger D.C., et al. Low-level environmental lead exposure and children's intellectual function: an international pooled analysis. Environ Health Perspect 2005, 113(7):894-899.
19. Lin T., Tai-Yi J. Benchmark dose approach for renal dysfunction in workers exposed to lead. Environ Toxicol 2007, 22(3):229-233.
20. Makino S., Tsuruta H., Takata T. Relationship between blood lead level and urinary ALA level in workers exposed to very low levels of lead. Ind Health 2000, 38(1):95-98.
21. Moerbeek M., Piersma A.H., Slob W. A comparison of three methods for calculating confidence intervals for the benchmark dose. Risk Anal 2004, 24(1):31-40.
22. Nakao K., Wada O., Yano Y. Delta-aminolevulinic acid dehydratase activity in erythrocytes for the evaluation of lead poisoning. Clin Chim Acta 1968, 19(2):319-325.
23. Sakai T. Reviews on biochemical markers of lead exposure with special emphasis on heme and nucleotide metabolisms. Sangyo Eiseigaku Zassshi 1995, 37:99-112.
24. Sakai T. Biomarkers of lead exposure. Ind Health 2000, 38(2):127-142.
25. Sand S., Victorin K., Filipsson A.F. The current state of knowledge on the use of the benchmark dose concept in risk assessment. J Appl Toxicol 2008, 28(4):405-421.
26. Shah F., Kazi T.G., Afridi H.I., Baig J.A., Khan S., Kolachi N.F., et al. Environmental exposure of lead and iron deficit anemia in children age ranged 1-5years: a cross sectional study. Sci Total Environ 2010, 408(22):5325-5330.
27. Shao B., Jin T.Y., Wu X.W., Kong Q.H., Ye T.T. Application of benchmark dose (BMD) in estimating biological exposure limit (BEL) to cadmium. Biomed Environ Sci 2007, 20(6):460-464.
28. Suwazono Y., Sakata K., Oishi M., Okubo Y., Dochi M., Kobayashi E., et al. Estimation of benchmark dose as the threshold amount of alcohol consumption for blood pressure in Japanese workers. Risk Anal 2007, 27(6):1487-1495.
29. Taketani S., Tanaka A., Tikunaga R. Reconstitution of heme-synthesizing activity from ferric ion and porphyrin, and the effect of lead on the activity. Arch Biochem Biophys 1985, 242(1):291-296.
30. Talkvist J., Bowlus C.L., Lonnerdal B. Functional and molecular responses of human intestinal Caco-2 cells to iron treatment. Am J Clin Nutr 2000, 72(3):770-775.
31. Tellez-Rojo M.M., Bellinger D.C., Arroyo-Quiroz C., Lamadrid-Figueroa H., Mercado-Garcia A., Schnaas-Arrieta L., et al. Longitudinal associations between blood lead concentrations lower than 10microg/dL and neurobehavioral development in environmentally exposed children in Mexico City. Pediatrics 2006, 118(2):e323-e330.
32. Tomokuni K., Hirai Y. Simple liquid-chromatographic determination of urinary coproporphyrin in workers exposed to lead. Clin Chem 1986, 32(5):872-873.
33. Tomokuni K., Ogata M. Simple method for determination of urinary-aminolevulinic acid as an index of lead exposure. Clin Chem 1972, 18(12):1534-1538.
34. USEPA EPA benchmark dose technical guidance document (BMDTG). Risk Assessment Forum 2000, U.S. Environmental Protection Agency, Washington, DC, EPA/630/R-00/001.
35. Wang S., Zhang J. Blood lead levels in children, China. Environ Res 2006, 101(3):412-418.
36. Wang Q., Zhao H.H., Chen J.W., Gu K.D., Zhang Y.Z., Zhu Y.X., et al. Adverse health effects of lead exposure on children and exploration to internal lead indicator. Sci Total Environ 2009, 407(23):5986-5992.
37. Wang Q., Zhao H.H., Chen J.W., Hao Q.L., Gu K.D., Zhu Y.X., et al. delta-Aminolevulinic acid dehydratase activitiy, urinary delta-aminolevulinic acid concentration and zinc protoporphyrin level among people with low level of lead exposure. Int J Hyg Environ Health 2010, 213(1):52-58.
38. Wright R.O., Shannon M.W., Wright R.J., Hu H. Association between iron deficiency and low-level lead poisoning in an urban primary care clinic. Am J Public Health 1999, 89(7):1049-1053.
39. Wright R.O., Tsaih S.W., Schwartz J., Wright R.J., Hu H. Association between iron deficiency and blood lead level in a longitudinal analysis of children followed in an urban primary care clinic. J Pediatr 2003, 142(1):9-14.