δ-Aminolevulinic acid dehydratase activity, urinary δ-aminolevulinic acid concentration and zinc protoporphyrin level among people with low level of lead exposure

International Journal of Hygiene and Environmental Health

Volumn 213, Issue 1, 2010, Pages 52-58

  Wang, Qi ^a   Zhao, Huan hu ^a   Chen, Jian wei ^b   Hao, Qiao ling ^b   Gu, Kang ding ^b   Zhu, Ye xiang ^b   Zhou, Yi kai ^b   Ye, Lin xiang ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Huazhong University of Science and Technology   (China)

Author keywords

Delta aminolevulinic acid; Delta aminolevulinic acid dehydratase; Lead; Zinc protoporphyrin XI

Indexed keywords

AMINOLEVULINIC ACID; BIOLOGICAL MARKER; LEAD; PORPHOBILINOGEN SYNTHASE; PROTOPORPHYRIN; PROTOPORPHYRIN ZINC;

ADULT; ARTICLE; BLOOD; CHILD; CHINA; DRINKING BEHAVIOR; ENVIRONMENTAL EXPOSURE; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; SEX DIFFERENCE; SMOKING; URINE;

ADULT; ALCOHOL DRINKING; AMINOLEVULINIC ACID; BIOLOGICAL MARKERS; CHILD; CHINA; ENVIRONMENTAL EXPOSURE; FEMALE; HUMANS; LEAD; MALE; MIDDLE AGED; PORPHOBILINOGEN SYNTHASE; PROTOPORPHYRINS; SEX FACTORS; SMOKING;

EID: 74149085093     PISSN: 14384639     EISSN: 1618131X     Source Type: Journal    
DOI: 10.1016/j.ijheh.2009.08.003     Document Type: Article

References (40)

1. ATSDR (Agency for Toxic Substances and Disease Registry), 1999. Toxicologic Profile for Lead: Update. US Department of Health and Human Services, Atlanta, GA, USA.
2. Barbosa Jr. F., Tanus-Santo J.E., Gerlach R.F., and Parsons P.J. A critical review of biomarkers used for monitoring human exposure to lead: advantages, limitations, and future needs. Environ. Health Perspect. 113 (2005) 1669-1674
3. Campagna D., Huel G., Girard F., Sahuquillo J., and Blot P. Environmental lead exposure and activity of δ-aminolevulinic acid dehydratase (ALA-D) in maternal and cord blood. Toxicology 134 (1999) 143-152
4. CDC, 1991. Preventing in lead poisoning in young children. A statement from the CDC, Atlanta, GA, CDC, pp. 1-2.
5. Finster M.E., Gray K.A., and Binns H.J. Lead levels of edibles grown in contaminated residential soils: a field survey. Sci. Total Environ. 320 (2004) 245-257
6. Froom P., Kristal-Boneh E., Benbassat J., Ashkanazi R., and Ribak J. Predictive value of determinations of zinc protoporphyrin for increased blood lead concentrations. Clin. Chem. 44 (1998) 1283-1288
7. Hastka J., Lasserre J.J., Schwarzbeck A., and Hehlmann R. Central role of zinc protoporphyrin in staging iron deficiency. Clin. Chem. 40 (1994) 768-773
8. Heinze I., Gross R., Stehle P., and Dillon D. Assessment of lead exposure in schoolchildren from Jakarta. Environ. Health Perspect. 106 (1998) 499-501
9. Hense H.W., Filipiak B., Novak L., and Stoeppler M. Nonoccupational determinants of blood lead concentrations in general population. Int. J. Epidemiol. 21 (1992) 753-762
10. Hershko C., Konijn A.M., Moreb J., Link G., Grauer F., and Weissenberg E. Iron depletion and blood lead levels in a population with endemic lead poisoning. Isr. J. Med. Sci. 20 (1984) 1039-1043
11. Higashikawa K., Furuki K., Takada S., Okamoto S., Ukai H., Yuasa T., and Ikeda M. Blood lead level to induce significant increase in urinary δ-aminolevulinic acid level among lead-exposed workers: a statistical approach. Ind. Health 38 (2000) 181-188
12. Kuliczkowski K. Lead concentration in the blood and aminolevulinic acid dehydratase (ALAD) activity in the erythrocytes depending on sex, age, tobacco smoking and alcohol drinking in the group of persons exposed to industrial dust. Med. Pr. 32 (1981) 99-107
13. Kwong W.T., Friello P., and Semba R.D. Interactions between iron deficiency and lead poisoning: epidemiology and pathogenesis. Sci. Total Environ. 330 (2004) 21-37
14. Labbé R.F., Vreman H.J., and Stevenson D.K. Zinc protoporphyrin: a metabolite with a mission. Clin. Chem. 45 (1999) 2060-2072
15. Lanphear B.P., Dietrich K., Auinger P., and Cox C. Cognitive deficits associated with blood lead concentrations <10 μg/dL in US children and adolescents. Public Health Rep. 115 (2000) 521-529
16. Leung F.Y., Bradley C., and Pellar T.G. Reference intervals for blood lead and evaluation of zinc protoporphyrin as a screening test for lead toxicity. Clin. Biochem. 36 (1993) 491-496
17. Makino S., Tsuruta H., and Takata T. Relationship between blood lead level and urinary ALA level in workers exposed to very low levels of lead. Ind. Health 38 (2000) 95-98
18. Mendelsohn A.L., Dreyer B.P., Fierman A.H., Rosen C.M., Legano L.A., Kruger H.A., Lim S.W., and Courtlandt C.D. Low-level lead exposure and behavior in early childhood. Pediatrics 101 (1998) E10
19. Meredith P.A., Moore M.R., Campbell B.C., Thompson G.G., and Goldberg A. Delta-aminolevulinci acid metabolism in normal and lead-exposed humans. Toxicology 9 (1978) 1-9
20. MHPRC (Ministry of Health of the People's Republic of China), 2002. Diagnostic Criteria of Occupational Chronic Lead Poisoning GBZ37-2002.
21. Ming L.O., Surif S., and Abdullah A. Lead exposure among Malaysian school children using δ-aminolevulinic acid as an indicator. Sci. Total Environ. 193 (1997) 207-213
22. Nakao K., Wada O., and Yano Y. δ-Aminolevulinic acid dehydratase activity in erythrocytes for the evaluation of lead poisoning. Clin. Chim. Acta 19 (1968) 319-325
23. Propić-Majić D., Tellisman S., and Kezić S. In vitro study on lead and alcohol interaction and the inhibition of erythrocyte delta-aminolevulinic acid dehydratase in man. Scand. J. Work Environ. Health 10 (1984) 235-238
24. Ragan H.A. Effects of iron deficiency on the absorption and distribution of lead cadmium in rats. J. Lab. Clin. Med. 90 (1977) 700-706
25. Rettmer R.L., Calson T.H., Origenes M.L., Jack R.M., and Labbé R.F. Zinc protoporphyrin/heme ratio for diagnosis of preanemic iron deficiency. Pediatrics 104 (1999) e37-e43
26. Robertson I.K., and Worwood M. Lead and iron absorption from rat small intestine: the effect of dietary Fe deficiency. Br. J. Nutr. 40 (1978) 253-260
27. Rondó P.H.C., Carvalho M.F.H., Souza M.C., and Moraes F. Lead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children. Rev. Saude. Publica. 40 (2006) 71-76
28. Sakai T. Reviews on biochemical markers of lead exposure with special emphasis on heme and nucleotide metabolisms. Sangyo Eiseigaku Zasshi 37 (1995) 99-112
29. Sakai T. Biomarkers of lead exposure. Ind. Health 38 (2000) 127-142
30. Sakai T., Yanagihara S., and Ushio K. Erythrocyte factors concerned in the inhibition of ALA-D by lead. Br. J. Ind. Med. 38 (1981) 268-274
31. Salle H.J.A., and Zielhuis R.L. Influence of smoking on aminolevulinic acid dehydratase activity, haematocrite and lead in blood in adult urban women. Int. Arch. Occup. Environ. Health 40 (1977) 111-115
32. Selander S., and Cramer K. Interrelationships between lead in blood, lead in urine, and ALA in urine during lead work. Br. J. Ind. Med. 27 (1970) 28-39
33. Six K.M., and Goyer R.A. The influence of iron deficiency on tissue content and toxicity of ingested lead in the rat. J. Lab. Clin. Med. 79 (1972) 128-136
34. Taketani S., Tanaka A., and Tikunaga R. Reconstitution of heme-synthesizing activity from ferric ion and porphyrin, and the effect of lead on the activity. Arch. Biochem. Biophys. 242 (1985) 291-296
35. Tellisman S., Propić-Majić D., and Kezić S. In vivo study on lead and alcohol interaction and the inhibition of erythrocyte delta-aminolevulinic acid dehydratase in man. Scand. J. Work Environ. Health 10 (1984) 239-244
36. Tola S., Hernberg S., Asp S., and Nikkanen J. Parameters indicative of absorption and biological effect in new lead exposure: prospective study. Br. J. Ind. Med. 30 (1973) 134-141
37. Tomokuni K., and Ogata M. Simple method for determination of urinary δ-aminolevulinic acid as an index of lead exposure. Clin. Chem. 18 (1972) 1534-1536
38. Wong S.S., Qutishat A.S., Lange J., Gornet T.G., and Mximilian Buja L. Detection of iron-deficiency anemia in hospitalized patients by zinc protoporphyrin. Clin. Chim. Acta 244 (1996) 91-101
39. Wright R.O., Tsaih S.W., Schwartz J., Wright R.J., and Hu H. Association between iron deficiency and blood lead level in a longitudinal analysis of children followed in an urban primary care clinic. J. Pediatr. 142 (2003) 9-14
40. Yip R., Johnson C., and Dallman P.R. Age-related changes in laboratory values used in diagnosis of anemia and iron deficiency. Am. J. Clin. Nutr. 39 (1984) 427-436