Overexpression of the orphan receptor Nur77 and its translocation induced by PCH4 may inhibit malignant glioma cell growth and induce cell apoptosis

Journal of Surgical Oncology

Volumn 103, Issue 5, 2011, Pages 442-450

  Chang, Li Fu ^a   Lin, Po Cheng ^a   Ho, Li Ing ^b   Liu, Po Yen ^c   Wu, Wan Chen ^c   Chiang, I Ping ^d   Chang, Hui Wen ^d   Lin, Shinn Zong ^c   Harn, Yeu Chern ^e   Harn, Horng Jyh ^c,d   Chiou, Tzyy Wen ^a  

^a NATIONAL DONG HWA UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

(Z) N (2 (dimethylamino)ethyl) 2 (3 ((3 oxoisobenzofuran 1(3H) ylidene)methyl) phenoxy)acetamide; Apoptosis; Glioblastoma multiform; JNK pathway; PCH4; The derivative of n butylidenephthalide

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTINEOPLASTIC AGENT; LIPOCORTIN 5; N (2 (DIMETHYLAMINO)ETHYL) 2 [[(3 OXOISOBENZOFURAN 1 (3H) YLIDENE)METHYL]PHENOXY]ACETAMIDE; NUCLEAR RECEPTOR NUR77; PCH 4; PHTHALIDE DERIVATIVE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DRUG RECEPTOR BINDING; GLIOBLASTOMA; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANGELICA SINENSIS; ANIMALS; APOPTOSIS; BENZOFURANS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL PROLIFERATION; DNA-BINDING PROTEINS; ETHYLAMINES; FLOW CYTOMETRY; GLIOBLASTOMA; HUMANS; LUCIFERASES; MAP KINASE KINASE 4; MICE; MICE, NUDE; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 2; PHTHALIC ANHYDRIDES; PROTEIN TRANSPORT; RECEPTORS, STEROID; RECEPTORS, THYROID HORMONE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79952620727     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.21809     Document Type: Article

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