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Volumn 120, Issue 12, 2011, Pages 505-514

Eszopiclone increases the respiratory arousal threshold and lowers the apnoea/hypopnoea index in obstructive sleep apnoea patients with a low arousal threshold

Author keywords

Apnoea hypopnoae index (AHI); Lung; Sedative medication; Sleep disordered breathing; Therapeutic target; Upper airway physiology

Indexed keywords

ESZOPICLONE; PLACEBO;

EID: 79952593642     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20100588     Document Type: Article
Times cited : (273)

References (50)
  • 1
    • 0027462562 scopus 로고
    • The occurrence of sleep-disordered breathing among middle-aged adults
    • Young, T., Palta, M., Dempsey, J., Skatrud, J., Weber, S. and Badr, S. (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N. Engl. J. Med. 328, 1230-1235
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1230-1235
    • Young, T.1    Palta, M.2    Dempsey, J.3    Skatrud, J.4    Weber, S.5    Badr, S.6
  • 3
    • 0344820724 scopus 로고    scopus 로고
    • The association between sleep apnea and the risk of traffic accidents
    • Cooperative Group Burgos-Santander
    • Teran-Santos, J., Jimenez-Gomez, A. and Cordero-Guevara, J. (1999) The association between sleep apnea and the risk of traffic accidents. Cooperative Group Burgos-Santander. N. Engl. J. Med. 340, 847-851
    • (1999) N. Engl. J. Med. , vol.340 , pp. 847-851
    • Teran-Santos, J.1    Jimenez-Gomez, A.2    Cordero-Guevara, J.3
  • 5
    • 0037317742 scopus 로고    scopus 로고
    • Improving CPAP use by patients with the sleep apnoea/hypopnoea syndrome (SAHS)
    • Engleman, H. M. and Wild, M. R. (2003) Improving CPAP use by patients with the sleep apnoea/hypopnoea syndrome (SAHS). Sleep Med. Rev. 7, 81-99
    • (2003) Sleep Med. Rev. , vol.7 , pp. 81-99
    • Engleman, H.M.1    Wild, M.R.2
  • 6
    • 0037106259 scopus 로고    scopus 로고
    • Randomized crossover trial of two treatments for sleep apnea/hypopnea syndrome: Continuous positive airway pressure and mandibular repositioning splint
    • Engleman, H. M., McDonald, J. P., Graham, D., Lello, G. E., Kingshott, R. N., Coleman, E. L., Mackay, T.W. and Douglas, N. J. (2002) Randomized crossover trial of two treatments for sleep apnea/hypopnea syndrome: continuous positive airway pressure and mandibular repositioning splint. Am. J. Respir. Crit. Care Med. 166, 855-859
    • (2002) Am. J. Respir. Crit. Care Med. , vol.166 , pp. 855-859
    • Engleman, H.M.1    McDonald, J.P.2    Graham, D.3    Lello, G.E.4    Kingshott, R.N.5    Coleman, E.L.6    Mackay, T.W.7    Douglas, N.J.8
  • 7
    • 38049022464 scopus 로고    scopus 로고
    • Pharmacological treatment of sleep apnea: Current situation and future strategies
    • Hedner, J., Grote, L. and Zou, D. (2008) Pharmacological treatment of sleep apnea: current situation and future strategies. Sleep Med. Rev. 12, 33-47
    • (2008) Sleep Med. Rev. , vol.12 , pp. 33-47
    • Hedner, J.1    Grote, L.2    Zou, D.3
  • 8
    • 39049164630 scopus 로고    scopus 로고
    • Pathophysiology of adult obstructive sleep apnea
    • Eckert, D. J. and Malhotra, A. (2008) Pathophysiology of adult obstructive sleep apnea. Proc. Am. Thorac. Soc. 5, 144-153
    • (2008) Proc. Am. Thorac. Soc. , vol.5 , pp. 144-153
    • Eckert, D.J.1    Malhotra, A.2
  • 9
    • 30344480217 scopus 로고    scopus 로고
    • Pathogenesis of obstructive and central sleep apnea
    • White, D. P. (2005) Pathogenesis of obstructive and central sleep apnea. Am. J. Respir. Crit. Care Med. 172, 1363-1370
    • (2005) Am. J. Respir. Crit. Care Med. , vol.172 , pp. 1363-1370
    • White, D.P.1
  • 11
    • 0026750217 scopus 로고
    • Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism)
    • Mezzanotte, W. S., Tangel, D. J. and White, D. P. (1992) Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism). J. Clin. Invest. 89, 1571-1579
    • (1992) J. Clin. Invest. , vol.89 , pp. 1571-1579
    • Mezzanotte, W.S.1    Tangel, D.J.2    White, D.P.3
  • 12
    • 35348958848 scopus 로고    scopus 로고
    • Mechanisms used to restore ventilation after partial upper airway collapse during sleep in humans
    • DOI 10.1136/thx.2006.070300
    • Jordan, A. S., Wellman, A., Heinzer, R. C., Lo, Y. L., Schory, K., Dover, L., Gautam, S., Malhotra, A. and White, D. P. (2007) Mechanisms used to restore ventilation after partial upper airway collapse during sleep in humans. Thorax 62, 861-867 (Pubitemid 47598350)
    • (2007) Thorax , vol.62 , Issue.10 , pp. 861-867
    • Jordan, A.S.1    Wellman, A.2    Heinzer, R.C.3    Lo, Y.-L.4    Schory, K.5    Dover, L.6    Gautam, S.7    Malhotra, A.8    White, D.P.9
  • 14
    • 1442300756 scopus 로고    scopus 로고
    • Role of arousals in the pathogenesis of obstructive sleep apnea
    • Younes, M. (2004) Role of arousals in the pathogenesis of obstructive sleep apnea. Am. J. Respir. Crit. Care Med. 169, 623-633
    • (2004) Am. J. Respir. Crit. Care Med. , vol.169 , pp. 623-633
    • Younes, M.1
  • 16
    • 0141617564 scopus 로고    scopus 로고
    • Contributions of upper airway mechanics and control mechanisms to severity of obstructive apnea
    • Younes, M. (2003) Contributions of upper airway mechanics and control mechanisms to severity of obstructive apnea. Am. J. Respir. Crit. Care Med. 168, 645-658
    • (2003) Am. J. Respir. Crit. Care Med. , vol.168 , pp. 645-658
    • Younes, M.1
  • 17
    • 0025282912 scopus 로고
    • The influence of increasing ventilatory effort on arousal from sleep
    • Gleeson, K., Zwillich, C. W. and White, D. P. (1990) The influence of increasing ventilatory effort on arousal from sleep. Am. Rev. Respir. Dis. 142, 295-300
    • (1990) Am. Rev. Respir. Dis. , vol.142 , pp. 295-300
    • Gleeson, K.1    Zwillich, C.W.2    White, D.P.3
  • 20
    • 79952595984 scopus 로고    scopus 로고
    • Defining physiological phenotypic traits in obstructive sleep apnea: Avenues for novel treatment approaches
    • Eckert, D. J., Jordan, A. S., Wellman, A., Malhotra, A. and White, D. P. (2009) Defining physiological phenotypic traits in obstructive sleep apnea: avenues for novel treatment approaches. Respirology 14, A21
    • (2009) Respirology , vol.14
    • Eckert, D.J.1    Jordan, A.S.2    Wellman, A.3    Malhotra, A.4    White, D.P.5
  • 21
    • 0026604619 scopus 로고
    • Effect of ethanol on the arousal response to airway occlusion during sleep in normal subjects
    • Berry, R. B., Bonnet, M. H. and Light, R. W. (1992) Effect of ethanol on the arousal response to airway occlusion during sleep in normal subjects. Am. Rev. Respir. Dis. 145, 445-452
    • (1992) Am. Rev. Respir. Dis. , vol.145 , pp. 445-452
    • Berry, R.B.1    Bonnet, M.H.2    Light, R.W.3
  • 23
    • 0026452390 scopus 로고
    • The effect of triazolam on the arousal response to airway occlusion during sleep in normal subjects
    • Berry, R. B., McCasland, C. R. and Light, R. W. (1992) The effect of triazolam on the arousal response to airway occlusion during sleep in normal subjects. Am. Rev. Respir. Dis. 146, 1256-1260
    • (1992) Am. Rev. Respir. Dis. , vol.146 , pp. 1256-1260
    • Berry, R.B.1    McCasland, C.R.2    Light, R.W.3
  • 26
    • 0021320511 scopus 로고
    • Selective reduction of genioglossal muscle activity by alcohol in normal human subjects
    • Krol, R. C., Knuth, S. L. and Bartlett, Jr, D. (1984) Selective reduction of genioglossal muscle activity by alcohol in normal human subjects. Am. Rev. Respir. Dis. 129, 247-250
    • (1984) Am. Rev. Respir. Dis. , vol.129 , pp. 247-250
    • Krol, R.C.1    Knuth, S.L.2    Bartlett Jr., D.3
  • 27
    • 0021912910 scopus 로고
    • Differential elevation by protriptyline and depression by diazepam of upper airway respiratory motor activity
    • Bonora, M., St John, W. M. and Bledsoe, T. A. (1985) Differential elevation by protriptyline and depression by diazepam of upper airway respiratory motor activity. Am. Rev. Respir. Dis. 131, 41-45
    • (1985) Am. Rev. Respir. Dis. , vol.131 , pp. 41-45
    • Bonora, M.1    St John, W.M.2    Bledsoe, T.A.3
  • 28
    • 0021947098 scopus 로고
    • The effect of diazepam on genioglossal muscle activity in normal human subjects
    • Leiter, J. C., Knuth, S. L., Krol, R. C. and Bartlett, Jr, D. (1985) The effect of diazepam on genioglossal muscle activity in normal human subjects. Am. Rev. Respir. Dis. 132, 216-219
    • (1985) Am. Rev. Respir. Dis. , vol.132 , pp. 216-219
    • Leiter, J.C.1    Knuth, S.L.2    Krol, R.C.3    Bartlett Jr., D.4
  • 29
    • 0027970326 scopus 로고
    • Nitrazepam in patients with sleep apnoea: A double-blind placebo-controlled study
    • Hoijer, U., Hedner, J., Ejnell, H., Grunstein, R., Odelberg, E. and Elam, M. (1994) Nitrazepam in patients with sleep apnoea: a double-blind placebo-controlled study. Eur. Respir. J. 7, 2011-2015
    • (1994) Eur. Respir. J. , vol.7 , pp. 2011-2015
    • Hoijer, U.1    Hedner, J.2    Ejnell, H.3    Grunstein, R.4    Odelberg, E.5    Elam, M.6
  • 30
    • 34250812495 scopus 로고    scopus 로고
    • A pilot study evaluating acute use of eszopiclone in patients with mild to moderate obstructive sleep apnea syndrome
    • Rosenberg, R., Roach, J. M., Scharf, M. and Amato, D. A. (2007) A pilot study evaluating acute use of eszopiclone in patients with mild to moderate obstructive sleep apnea syndrome. Sleep Med. 8, 464-470
    • (2007) Sleep Med. , vol.8 , pp. 464-470
    • Rosenberg, R.1    Roach, J.M.2    Scharf, M.3    Amato, D.A.4
  • 32
    • 0031457176 scopus 로고    scopus 로고
    • Effect of zopiclone on sleep, night-time ventilation, and daytime vigilance in upper airway resistance syndrome
    • Lofaso, F., Goldenberg, F., Thebault, C., Janus, C. and Harf, A. (1997) Effect of zopiclone on sleep, night-time ventilation, and daytime vigilance in upper airway resistance syndrome. Eur. Respir. J. 10, 2573-2577
    • (1997) Eur. Respir. J. , vol.10 , pp. 2573-2577
    • Lofaso, F.1    Goldenberg, F.2    Thebault, C.3    Janus, C.4    Harf, A.5
  • 33
    • 77949328584 scopus 로고    scopus 로고
    • Can improving sleep influence sleep-disordered breathing?
    • Series, F. (2009) Can improving sleep influence sleep-disordered breathing? Drugs 69, 77-91
    • (2009) Drugs , vol.69 , pp. 77-91
    • Series, F.1
  • 34
    • 33745148838 scopus 로고    scopus 로고
    • Sedating medications and undiagnosed obstructive sleep apnea: Physician determinants and patient consequences
    • Lu, B., Budhiraja, R. and Parthasarathy, S. (2005) Sedating medications and undiagnosed obstructive sleep apnea: physician determinants and patient consequences. J. Clin. Sleep Med. 1, 367-371
    • (2005) J. Clin. Sleep Med. , vol.1 , pp. 367-371
    • Lu, B.1    Budhiraja, R.2    Parthasarathy, S.3
  • 35
    • 65349143829 scopus 로고    scopus 로고
    • Improvement of idiopathic central sleep apnea with zolpidem
    • Quadri, S., Drake, C. and Hudgel, D. W. (2009) Improvement of idiopathic central sleep apnea with zolpidem. J. Clin. Sleep Med. 5, 122-129
    • (2009) J. Clin. Sleep Med. , vol.5 , pp. 122-129
    • Quadri, S.1    Drake, C.2    Hudgel, D.W.3
  • 36
    • 64749100459 scopus 로고    scopus 로고
    • The influence of obstructive sleep apnea and gender on genioglossus activity during rapid eye movement sleep
    • Eckert, D. J., Malhotra, A., Lo, Y. L., White, D. P. and Jordan, A. S. (2009) The influence of obstructive sleep apnea and gender on genioglossus activity during rapid eye movement sleep. Chest 135, 957-964
    • (2009) Chest , vol.135 , pp. 957-964
    • Eckert, D.J.1    Malhotra, A.2    Lo, Y.L.3    White, D.P.4    Jordan, A.S.5
  • 37
    • 0033083891 scopus 로고    scopus 로고
    • Arousal threshold to respiratory stimuli in OSA patients: Evidence for a sleep-dependent temporal rhythm
    • Sforza, E., Krieger, J. and Petiau, C. (1999) Arousal threshold to respiratory stimuli in OSA patients: evidence for a sleep-dependent temporal rhythm. Sleep 22, 69-75 (Pubitemid 29097900)
    • (1999) Sleep , vol.22 , Issue.1 , pp. 69-75
    • Sforza, E.1    Krieger, J.2    Petiau, C.3
  • 39
    • 0026769267 scopus 로고
    • EEG arousals: Scoring rules and examples: A preliminary report from the Sleep Disorders Atlas Task Force of the American Sleep Disorders Association
    • American Sleep Disorders Association
    • American Sleep Disorders Association (1992) EEG arousals: scoring rules and examples: a preliminary report from the Sleep Disorders Atlas Task Force of the American Sleep Disorders Association. Sleep 15, 173-184
    • (1992) Sleep , vol.15 , pp. 173-184
  • 41
    • 0021871231 scopus 로고
    • Apnea duration and hypoxemia during REM sleep in patients with obstructive sleep apnea
    • Findley, L. J., Wilhoit, S. C. and Suratt, P. M. (1985) Apnea duration and hypoxemia during REM sleep in patients with obstructive sleep apnea. Chest 87, 432-436
    • (1985) Chest , vol.87 , pp. 432-436
    • Findley, L.J.1    Wilhoit, S.C.2    Suratt, P.M.3
  • 42
    • 34250000542 scopus 로고    scopus 로고
    • Genioglossus reflex inhibition to upper-airway negative-pressure stimuli during wakefulness and sleep in healthy males
    • Eckert, D. J., McEvoy, R. D., George, K. E., Thomson, K. J. and Catcheside, P. G. (2007) Genioglossus reflex inhibition to upper-airway negative-pressure stimuli during wakefulness and sleep in healthy males. J. Physiol. 581, 1193-1205
    • (2007) J. Physiol. , vol.581 , pp. 1193-1205
    • Eckert, D.J.1    McEvoy, R.D.2    George, K.E.3    Thomson, K.J.4    Catcheside, P.G.5
  • 43
    • 0033231505 scopus 로고    scopus 로고
    • Effect of wake-sleep transitions and rapid eye movement sleep on pharyngeal muscle response to negative pressure in humans
    • DOI 10.1111/j.1469-7793.1999.00897.x
    • Shea, S. A., Edwards, J. K. and White, D. P. (1999) Effect of wake-sleep transitions and rapid eye movement sleep on pharyngeal muscle response to negative pressure in humans. J. Physiol. 520, 897-908 (Pubitemid 29533044)
    • (1999) Journal of Physiology , vol.520 , Issue.3 , pp. 897-908
    • Shea, S.A.1    Edwards, J.K.2    White, D.P.3
  • 44
    • 76549112725 scopus 로고    scopus 로고
    • Upper airway function and arousability to ventilatory challenge in slow wave versus stage 2 sleep in obstructive sleep apnoea
    • Ratnavadivel, R., Stadler, D., Windler, S., Bradley, J., Paul, D., McEvoy, R. D. and Catcheside, P. G. (2010) Upper airway function and arousability to ventilatory challenge in slow wave versus stage 2 sleep in obstructive sleep apnoea. Thorax 65, 107-112
    • (2010) Thorax , vol.65 , pp. 107-112
    • Ratnavadivel, R.1    Stadler, D.2    Windler, S.3    Bradley, J.4    Paul, D.5    McEvoy, R.D.6    Catcheside, P.G.7
  • 45
    • 76549122902 scopus 로고    scopus 로고
    • Stable breathing through deeper sleeping
    • Saboisky, J., Eckert, D. and Malhotra, A. (2010) Stable breathing through deeper sleeping. Thorax 65, 95-96
    • (2010) Thorax , vol.65 , pp. 95-96
    • Saboisky, J.1    Eckert, D.2    Malhotra, A.3
  • 46
    • 34247642595 scopus 로고    scopus 로고
    • Pentobarbital sedation increases genioglossus respiratory activity in sleeping rats
    • Younes, M., Park, E. and Horner, R. L. (2007) Pentobarbital sedation increases genioglossus respiratory activity in sleeping rats. Sleep 30, 478-488
    • (2007) Sleep , vol.30 , pp. 478-488
    • Younes, M.1    Park, E.2    Horner, R.L.3
  • 48
    • 77953165855 scopus 로고    scopus 로고
    • The effect of short sleep duration on coronary heart disease risk is greatest among those with sleep disturbance: A prospective study from the White hall II cohort
    • Chandola, T., Ferrie, J. E., Perski, A., Akbaraly, T. and Marmot, M. G. (2010) The effect of short sleep duration on coronary heart disease risk is greatest among those with sleep disturbance: a prospective study from the White hall II cohort. Sleep 33, 739-744
    • (2010) Sleep , vol.33 , pp. 739-744
    • Chandola, T.1    Ferrie, J.E.2    Perski, A.3    Akbaraly, T.4    Marmot, M.G.5
  • 49
    • 0031031348 scopus 로고    scopus 로고
    • Heart-lung interactions: Applications in the critically ill
    • Fessler, H. E. (1997) Heart-lung interactions: applications in the critically ill. Eur. Respir. J. 10, 226-237
    • (1997) Eur. Respir. J. , vol.10 , pp. 226-237
    • Fessler, H.E.1
  • 50
    • 0023866998 scopus 로고
    • Effects of left ventricular loading by negative intrathoracic pressure in dogs
    • Hausknecht, M. J., Brin, K. P., Weisfeldt, M. L., Permutt, S. and Yin, F. C. (1988) Effects of left ventricular loading by negative intrathoracic pressure in dogs. Circ. Res. 62, 620-631
    • (1988) Circ. Res. , vol.62 , pp. 620-631
    • Hausknecht, M.J.1    Brin, K.P.2    Weisfeldt, M.L.3    Permutt, S.4    Yin, F.C.5


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