Regulating the quorum sensing signalling circuit to control bacterial virulence: In silico analysis

IET Systems Biology

Volumn 5, Issue 2, 2011, Pages 103-109

  Karafyllidis, I G ^a  

^a DEMOCRITUS UNIVERSITY OF THRACE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL DRUG; AUTOINDUCERS; BACTERIAL INFECTIONS; CELL DENSITY; COMMUNICATION MECHANISMS; CONFINED SPACE; IN-SILICO; NUMERICAL EXPERIMENTS; PATHOGENIC BACTERIUM; QUORUM-SENSING; SIMULATION TOOL; STATE TRANSITION GRAPHS; VIRULENCE FACTORS;

BACTERIA; COMPUTER SIMULATION; TOOLS;

BACTERIOLOGY;

ARTICLE; BACTERIAL PHENOMENA AND FUNCTIONS; BACTERIUM; BIOLOGICAL MODEL; COMPUTER SIMULATION; METHODOLOGY; PATHOGENICITY; PHYSIOLOGY; QUORUM SENSING; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY; VIRULENCE;

BACTERIA; BACTERIAL PHYSIOLOGICAL PHENOMENA; COMPUTER SIMULATION; MODELS, BIOLOGICAL; QUORUM SENSING; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY; VIRULENCE;

BACTERIA (MICROORGANISMS);

EID: 79952582416     PISSN: 17518849     EISSN: None     Source Type: Journal    
DOI: 10.1049/iet-syb.2010.0018     Document Type: Article

References (36)

1. Diggle, S.P., Crusz, S.A., and Cámara, M.: 'Quorum sensing', Curr. Biol., 2007, 17, p. R907-R91010.1016/j.cub.2007.08.045
2. Bassler, B.L.: 'How bacteria talk to each other: regulation of gene expression by quorum sensing', Curr. Opin. Microbiol., 1999, 2, p. 582-58710.1016/S1369-5274(99)00025-9
3. Bassler, B.L., and Losick, R.: 'Bacterially speaking', Cell, 2006, 125, p. 237-24610.1016/j.cell.2006.04.001
4. Diggle, S.P., Gardner, A., West, S.A., and Griffin, A.S.: 'Evolutionary theory of bacterial quorum sensing: when is a signal not a signal?', Philos. Trans. R. Soc. B, 2007, 362, p. 1241-124910.1098/rstb.2007.2049
5. Nealson, K.H., Platt, T., and Hastings, J.W.: 'Cellular control of the synthesis and activity of the bacterial luminescent system', J. Bacteriol., 1970, 104, p. 313-322
6. Nealson, K.H., and Hastings, J.W.: 'Bacterial bioluminescence: its control and ecological significance', Microbiol. Rev., 1979, 43, p. 496-518
7. Xavier, K.B., and Bassler, B.L.: 'LuxS quorum sensing: more than just a numbers game', Curr. Opin. Microbiol., 2003, 6, p. 191-19710.1016/S1369-5274(03)00028-6
8. Hammer, B.K., and Bassler, B.L.: 'Quorum sensing controls biofilm formation in Vibrio cholerae', Mol. Microbiol., 2003, 50, p. 101-11410.1046/j.1365-2958.2003.03688.x
9. Juhas, M., Eberl, L., and Tümmler, B.: 'Quorum sensing: the power of cooperation in the world of Pseudomonas', Environ. Microbiol., 2005, 7, p. 459-47110.1111/j.1462-2920.2005.00769.x
10. Rasmussen, T.B., and Givskov, M.: 'Quorum sensing inhibitors: a bargain of effects', Microbiology, 2006, 152, p. 895-90410.1099/mic.0.28601-0
11. Haseltine, E.L., and Arnold, F.H.: 'Implications of rewiring bacterial quorum sensing', Appl. Environ. Microbiol., 2008, 74, p. 437-44510.1128/AEM.01688-07
12. Hentzer, M., Wu, H., and Andersen, J.B.: et al. 'Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors', EMBO J., 2003, 22, p. 3803-381510.1093/emboj/cdg366
13. Rasmussen, T.B., Bjarnsholt, T., and Skindersoe, M.E., et al.: 'Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector', J. Bacteriol., 2005, 187, p. 1799-181410.1128/JB.187.5.1799-1814.2005
14. Redfield, R.J.: 'Is quorum sensing a side effect of diffusion sensing?', Trends Microbiol., 2002, 10, p. 365-37010.1016/S0966-842X(02)02400-9
15. Fuqua, W.C., Winans, S.C., and Greenberg, E.P.: 'Quorum sensing in bacteria: the LuxR-LuxI family of cell density-responsive transcriptional regulators', J. Bacteriol., 1994, 176, p. 269-275
16. Sitnikov, D.M., Schineller, J.B., and Baldwin, T.O.: 'Transcriptional regulation of bioluminescence genes from Vibrio fisheri', Mol. Microbiol., 1995, 17, p. 801-81210.1111/j.1365-2958.1995.mmi_17050801.x
17. Diggle, S.P., Griffin, A.S., Campbell, G.S., and West, S.A.: 'Cooperation and conflict in quorum sensing bacterial populations', Nature, 2007, 450, p. 411-41410.1038/nature06279 0028-0836
18. Rumbaugh, K.P., Griswold, J.A., Iglewski, B.H., and Hamood, A.N.: 'Contribution of quorum sensing to the virulence of Pseudomonas aeruginosa in burn wound infections', Infect. Immun., 1999, 67, p. 5854-5862
19. Tinsley, M.R., Taylor, A.F., Huang, Z., and Showalter, K.: 'Emergence of collective behaviour in groups of excitable catalyst-loaded particles: spatiotemporal dynamical quorum sensing', Phys. Rev. Lett., 2009, 102, p. 158301-1-158301-410.1103/PhysRevLett.102.158301 0031-9007
20. Ward, J.P., King, J.R., Koerber, A.J., Williams, P., Croft, J.M., and Sockett, R.E.: 'Mathematical modelling of quorum sensing in bacteria', IMA J. Math. Appl. Med. Biol., 2001, 18, p. 263-29210.1093/imammb/18.3.263
21. Chopp, D.L., Kirisits, M.J., Moran, B., and Parsek, M.R.: 'A mathematical model of quorum sensing in a growing bacterial biofilm', J. Ind. Microbiol. Biotechnol., 2002, 29, p. 339-34610.1038/sj.jim.7000316
22. Klapper, I.: 'Effect of heterogeneous structure in mechanically unstressed biofilms on overall growth', Bull. Math. Biol., 2004, 66, p. 809-82410.1016/j.bulm.2003.11.008 0092-8240
23. Dockery, J., and Klapper, I.: 'Finger formation in biofilm layers', SIAM J. Appl. Math., 2001, 62, p. 853-8690036-1399
24. Chopp, D.L., Kirisits, M.J., Moran, B., and Parsek, M.R.: 'The dependence of quorum sensing on the depth of a growing biofilm', Bull. Math. Biol., 2003, 65, p. 1053-107910.1016/S0092-8240(03)00057-0 0092-8240
25. Kirisits, M.J., Margolis, J.J., and Purevdorj-Gage, B.L.: et al. 'Influence of the hydrodynamic environment on quorum sensing in Pseudomonas aeruginosa biofilms', J. Bacteriol., 2007, 189, p. 8357-836010.1128/JB.01040-07
26. Shrout, J.D., Chopp, D.L., Just, C.L., Hentzer, M., Givskov, M., and Parsek, M.R.: 'The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional', Mol. Microbiol., 2006, 62, p. 1264-127710.1111/j.1365-2958.2006.05421.x
27. Klapper, I., and Dockery, J.: 'Role of cohesion in the material description of biofilms', Phys. Rev. E, 2006, 74, p. 03190210.1103/PhysRevE.74.031902
28. Lamma, E., Mello, P., Nanetti, A., Riguzzi, F., Storari, S., and Valastro, G.: 'Artificial intelligence techniques for monitoring dangerous infections', IEEE Trans. Inf. Technol. Biomed., 2006, 10, p. 143-15510.1109/TITB.2005.855537 1089-7771
29. Hense, B.A., Kuttler, C., Müller, J., Rothballer, M., Hartmann, A., and Kreft, J.U.: 'Does efficiency sensing unify diffusion and quorum sensing?', Nat. Rev. Microbiol., 2007, 5, p. 230-23910.1038/nrmicro1600
30. Sneddon, I.N.: 'Elements of partial differential equations', (Dover Publications, London 2006)
31. Ames, W.F.: 'Numerical methods for partial differential equations', (Academic Press, Boston 1992)
32. Elowitz, M.B., Levine, A.J., and Siggia, E.D.: 'Stochastic gene expression in a single cell', Science, 2002, 297, p. 1183-118610.1126/science.1070919 0036-8075
33. Long, T., Tu, C.K., and Wang, Y.: et al. 'Quantifying the integration of quorum-sensing signals with single cell resolution', PloS Biol., 2009, 7, p. 0640-0649
34. Fisher, J., and Henzinger, T.A.: 'Executable cell biology', Nat. Biotechnol., 2007, 25, p. 1239-124910.1038/nbt1356
35. Fisher, J., Piterman, N., Hubbard, E.J.A., Stern, M.J., and Harel, D.: 'Computational insights into Caenorhabditis elegans vulval development', Proc. Natl. Acad. Sci., 2005, 102, p. 1951-195610.1073/pnas.0409433102
36. Givskov, M., Denys, R., and Manefield, E.: et al. 'Eukaryotic interference with homoserine lactone-mediated prokaryotic signaling', J. Bacteriol., 1996, 178, p. 6618-6622