Kisspeptin-evoked calcium signals in isolated primary rat gonadotropin-releasing hormone neurones

Neuroendocrinology

Volumn 93, Issue 2, 2011, Pages 114-120

  Kroll, Heike ^a   Bolsover, Stephen ^a   Hsu, Judith ^a   Kim, Soo Hyun ^b   Bouloux, Pierre Marc ^c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Calcium; Kisspeptin; Metastin; Signal transduction

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; CALCIUM; DYE; FURA RED; GONADORELIN; KISSPEPTIN; KISSPEPTIN 10; TETRODOTOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ISOLATION; CONTROLLED STUDY; CYTOSOL; EVOKED RESPONSE; EXTRACELLULAR MATRIX; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

AGE FACTORS; ANIMALS; CALCIUM SIGNALING; CELL CULTURE TECHNIQUES; CYTOSOL; GONADOTROPIN-RELEASING HORMONE; GREEN FLUORESCENT PROTEINS; IMIDAZOLES; NEURONS; RATS; RATS, TRANSGENIC; RATS, WISTAR; SIGNAL TRANSDUCTION; TETRODOTOXIN; TUMOR SUPPRESSOR PROTEINS;

EID: 79952575515     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000321678     Document Type: Article

References (39)

1. Krsmanovic LZ, et al: Calcium signaling and episodic secretion of gonadotropin-releasing hormone in hypothalamic neurons. Proc Natl Acad Sci USA 1992; 89: 8462-8466.
2. Nunemaker CS, et al: Gonadotropin-releasing hormone neurons generate interacting rhythms in multiple time domains. Endocrinology 2003; 144: 823-831. (Pubitemid 36262849)
3. Van Goor F, et al: Control of action potential-driven calcium influx in GT1 neurons by the activation status of sodium and calcium channels. Mol Endocrinol 1999; 13:587-603. (Pubitemid 30636426)
4. Watanobe H: Leptin directly acts within the hypothalamus to stimulate gonadotropin-releasing hormone secretion in vivo in rats. J Physiol 2002; 545: 255-268.
5. Smith JT, et al: KiSS-1 neurones are direct targets for leptin in the ob/ob mouse. J Neuroendocrinol 2006; 18: 298-303. (Pubitemid 43323951)
6. Grattan DR, et al: Prolactin regulation of gonadotropin-releasing hormone neurons to suppress luteinizing hormone secretion in mice. Endocrinology 2007; 148: 4344-4351. (Pubitemid 47295691)
7. Gottsch ML, et al: A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology 2004; 145: 4073-4077. (Pubitemid 39120554)
8. Kuohung W, Kaiser UB: GPR54 and KiSS-1: role in the regulation of puberty and reproduction. Rev Endocr Metab Disord 2006; 7:257-263. (Pubitemid 46399311)
9. Kotani M, et al: The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem 2001; 276: 34631-34636.
10. Irwig MS, et al: Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat. Neuroendocrinology 2004; 80: 264-272. (Pubitemid 40187012)
11. Han SK, et al: Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty. J Neurosci 2005; 25: 11349-11356.
12. Herbison AE, et al: Distribution and postnatal development of Gpr54 gene expression in mouse brain and gonadotropin-releasing hormone neurons. Endocrinology 2010; 151:312-321.
13. Ohtaki T, et al: Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. Nature 2001; 411: 613-617. (Pubitemid 32531412)
14. Messager S, et al: Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proc Natl Acad Sci USA 2005; 102: 1761-1766. (Pubitemid 40209241)
15. de Roux N, et al: Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc Natl Acad Sci USA 2003; 100: 10972-10976.
16. Seminara SB, et al: The GPR54 gene as a regulator of puberty. N Engl J Med 2003; 349:1614-1627. (Pubitemid 37303886)
17. d'Anglemont de Tassigny X, et al: Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. Proc Natl Acad Sci USA 2007; 104: 10714-10719.
18. Lapatto R, et al: Kiss1-/- mice exhibit more variable hypogonadism than Gpr54-/- mice. Endocrinology 2007; 148: 4927-4936. (Pubitemid 47481551)
19. Muir AI, et al: AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1. J Biol Chem 2001; 276: 28969-28975.
20. Zhang C, et al: Kisspeptin depolarizes gonadotropin-releasing hormone neurons through activation of TRPC-like cationic channels. J Neurosci 2008; 28: 4423-4434.
21. Pielecka-Fortuna J, Chu Z, Moenter SM: Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol. Endocrinology 2008; 149: 1979-1986. (Pubitemid 351468349)
22. Liu X, Lee K, Herbison AE: Kisspeptin excites gonadotropin-releasing hormone (GnRH) neurons through a phospholipase C/calcium-dependent pathway regulating multiple ion channels. Endocrinology 2008; 149: 4605-4614.
23. Constantin S, et al: Kisspeptin-10 facilitates a plasma membrane-driven calcium oscillator in gonadotropin-releasing hormone-1 neurons. Endocrinology 2009; 150: 1400-1412.
24. Fujioka H, et al: Generation of transgenic rats expressing enhanced green fluorescent protein in gonadotropin-releasing hormone neurons. J Reprod Dev 2003; 49: 523-529.
25. 2+ /phosphatidylserine-binding region of the C2 domain in the translocation of protein kinase C alpha to the plasma membrane. J Biol Chem 2003; 278: 10282-10290.
26. Charles AC, Hales TG: Mechanisms of spontaneous calcium oscillations and action potentials in immortalized hypothalamic (GT1-7) neurons. J Neurophysiol 1995; 73: 56-64.
27. Jasoni CL, et al: Cell type-specific expression of a genetically encoded calcium indicator reveals intrinsic calcium oscillations in adult gonadotropin-releasing hormone neurons. J Neurosci 2007; 27: 860-867. (Pubitemid 46174506)
28. Quaynor S, et al: Expression of a functional g protein-coupled receptor 54-kisspeptin autoregulatory system in hypothalamic gonadotropin-releasing hormone neurons. Mol Endocrinol 2007; 21: 3062-3070. (Pubitemid 350223515)
29. Merritt JE, et al: SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. Biochem J 1990; 271: 515-522. (Pubitemid 20344770)
30. d'Anglemont de Tassigny X, et al: Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals. Endocrinology 2008; 149: 3926-3932.
31. Putney JW Jr: A model for receptor-regulated calcium entry. Cell Calcium 1986; 7: 1-12.
32. Van Goor F, et al: Coordinate regulation of gonadotropin-releasing hormone neuronal firing patterns by cytosolic calcium and store depletion. Proc Natl Acad Sci USA 1999; 96: 4101-4106. (Pubitemid 29169043)
33. Nilius B, Voets T: TRP channels: a TR(I)P through a world of multifunctional cation channels. Pflügers Arch 2005; 451: 1-10.
34. Lalo U, Kostyuk P: Developmental changes in purinergic calcium signalling in rat neocortical neurones. Brain Res Dev Brain Res 1998; 111: 43-50. (Pubitemid 28520244)
35. 2+ changes during cerebral energy deprivation. Brain Res 1998; 796: 125-131.
36. Ramsey IS, Delling M, Clapham DE: An introduction to TRP channels. Ann Rev Physiol 2006; 68: 619-647.
37. Talavera K, Nilius B, Voets T: Neuronal TRP channels: thermometers, pathfinders and life-savers. Trends Neurosci 2008; 31: 287-295.
38. Sabatier N, Shibuya I, Dayanithi G: Intracellular calcium increase and somatodendritic vasopressin release by vasopressin receptor agonists in the rat supraoptic nucleus: involvement of multiple intracellular transduction signals. J Neuroendocrinol 2004; 16: 221-236. (Pubitemid 38425796)
39. Lu X, Ellis-Davies GC, Levitan ES: Calcium requirements for exocytosis do not delimit the releasable neuropeptide pool. Cell Calcium 2003; 33: 267-271. (Pubitemid 36348151)