Depletion of intracellular CA2+ stores or lowering extracellular calcium alters intracellular Ca2+ changes during cerebral energy deprivation

Brain Research

Volumn 796, Issue 1-2, 1998, Pages 125-131

  Grøndahl, Tor Ø ^a   Hablitz, John J ^b   Langmoen, Iver A ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Calcium; Cerebral ischemia anoxia; CLSM; Fluo 3 Fura Red; Hippocampus; Thapsigargin

Indexed keywords

CALCIUM ION; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; THAPSIGARGIN; ANILINE DERIVATIVE; BENZOFURAN DERIVATIVE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; FLUO 3; FLUORESCENT DYE; FURA RED; IMIDAZOLE DERIVATIVE; XANTHENE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN METABOLISM; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CONFOCAL LASER MICROSCOPY; ENERGY METABOLISM; EXTRACELLULAR CALCIUM; EXTRACELLULAR SPACE; HIPPOCAMPUS; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR OCCUPANCY; ANIMAL; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECT; IN VITRO STUDY; INTRACELLULAR MEMBRANE; METABOLISM; OSMOLARITY; PHYSIOLOGY; PYRAMIDAL NERVE CELL; WISTAR RAT;

ANILINE COMPOUNDS; ANIMALS; BENZOFURANS; CALCIUM; CALCIUM CHANNEL BLOCKERS; ENERGY METABOLISM; EXTRACELLULAR SPACE; FLUORESCENT DYES; HIPPOCAMPUS; IMIDAZOLES; INTRACELLULAR MEMBRANES; MICROSCOPY, CONFOCAL; OSMOLAR CONCENTRATION; PYRAMIDAL CELLS; RATS; RATS, WISTAR; THAPSIGARGIN; XANTHENES;

EID: 0032525435     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(98)00279-0     Document Type: Article

References (43)

1. Blatter L.A., Wier W.G. Intracellular diffusion, binding, and compartmentalization of the fluorescent calcium indicators Indo-1 and Fura-2. Biophys. J. 58:1990;1491-1499.
2. Burgoyne R.D., Cheek T.R. Locating intracellular calcium stores. Trends Biochem. Sci. 16:1991;319-320. [Review].
3. Choi D.W. Glutamate neurotoxicity in cortical cell culture is calcium dependent. Neurosci. Lett. 58:1985;293-297.
4. Dubinsky J.M., Rothman S.M. Intracellular calcium concentrations during 'chemical hypoxia' and excitotoxic neuronal injury. J. Neurosci. 11:1991;2545-2551.
5. Edwards F.A., Konnerth A., Sakmann B., Takahashi T. A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Pflüg. Arch. 414:1989;600-612.
6. 2+-release channels. TiPS. 15:1994;145-149.
7. Ferris C.D., Snyder S.H. Inositol 1,4,5-trisphosphate-activated calcium channels. Annu. Rev. Physiol. 54:1992;469-488.
8. Frandsen A., Schousboe A. Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neurons. Proc. Natl. Acad. Sci. USA. 89:1992;2590-2594.
9. o. J. Neurosci. 13:1993;63-72.
10. Gericke M., Droogmans G., Nilius B. Thapsigargin discharges intracellular calcium stores and induces transmembrane currents in human endothelial cells. Pflug. Arch. 422:1993;552-557.
11. 2+ solutions. J. Neurosci. 6:1986;3144-3151.
12. Greenberg J.H., Uematsu D., Araki N. Cytosolic free calcium during focal cerebral ischemia and the effects of nimodipine on calcium and histologic damage. Stroke. 21(Suppl. 4):1990;72-77.
13. ++ released from intracellular stores during cerebral energy deprivation. Neurol. Res. 18:1996;499-504.
14. ++ changes in hippocampal CA 1 neurons during energy deprivation. Brain. Res. 785:1998;58-65.
15. Hansen A.J., Zeuthen T. Extracellular ion concentrations during spreading depression and ischemia in the rat brain cortex. Acta Physiol. Scand. 113:1981;437-445.
16. Harkins A.B., Kurebayashi N., Baylor S.M. Resting myoplasmic free calcium in frog skeletal muscle fibers estimated with Fluo-3. Biophys. J. 65:1993;865-881.
17. Harris R.J., Symon L., Branston N.M., Bayhan M. Changes in extracellular calcium activity in cerebral ischemia. J. Cereb. Blood Flow Metab. 1:1981;203-209.
18. Harvey J., Collingridge G.L. Thapsigargin blocks the induction of long-term potentiation in rat hippocampal slices. Neurosci. Lett. 139:1992;197-200.
19. Haas H.L., Schaerer B., Vosmansky M. A simple perfusion chamber for the study of nervous tissue slices in vitro. J. Neurosci. Met. 1:1979;323-325.
20. 2+ without generation of inositol phosphates in NG115-401L neuronal cells. Biochem. J. 253:1988;81-86.
21. Kass I.S., Lipton P. Mechanisms involved in irreversible anoxic damage to the in vitro rat hippocampal slice. J. Physiol. 332:1982;459-472.
22. Kass I.S., Lipton P. Calcium and long-term transmission damage following anoxia in dentate gyrus and CA 1 regions of the rat hippocampal slice. J. Physiol. 378:1986;313-334.
23. Kirino T., Robinson H.P., Miwa A., Tamura A., Kawai N. Disturbance of membrane function preceding ischemic delayed neuronal death in the gerbil hippocampus. J. Cereb. Blood Flow Metab. 12:1992;408-417.
24. Kurebayashi N., Harkins A.B., Baylor S.M. Use of Fura Red as an intracellular calcium indicator in frog skeletal muscle fibers. Biophys. J. 64:1993;1934-1960.
25. I.A. Langmoen, P. Andersen, The hippocampal slice in vitro: a description of the technique and some examples of the opportunities it offers, in: G.A. Kerkut, H.V. Wheal (Eds.), Electrophysiology of Isolated Mammalian CNS Preparations, Academic Press, London, 1981, pp. 51-105.
26. 2+ prevents neurotoxicity. Brain Res. 598:1992;196-202.
27. Lynch G., Larson J., Kelso S., Barrionuevo G., Schottler F. Intracellular injections of EGTA block induction of hippocampal long-term potentiation. Nature. 305:1983;719-721.
28. 2+ in mammalian neurons. Trends Pharmacol. Sci. 11:1990;254-260.
29. i. Biophys. J. 65:1993;561-562.
30. Opitz T., Reymann K.G. Blockade of metabotropic glutamate receptors protects rat CA1 neurons from hypoxic injury. Neuroreport. 2:1991;455-457.
31. Roberts E.L.J., Sick T.J. Calcium-sensitive recovery of extracellular potassium and synaptic transmission in rat hippocampal slices exposed to brief anoxia. Brain Res. 456:1988;113-119.
32. Ross W.N. Calcium on the level. Biophys. J. 64:1993;1655-1656.
33. Rotnes J.S., Iversen J.G. Thapsigargin reveals evidence for fMLP-insensitive calcium pools in human leukocytes. Cell Calcium. 13:1992;487-500.
34. Schoepp D., Bockaert J., Sladeczek F. Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors. Trends Pharmacol. Sci. 11:1990;508-515.
35. Siesjö B.K., Bengtsson F. Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis. J. Cereb. Blood Flow Metab. 9:1989;127-140.
36. 2+] in hypoxia and ischemia in rat brain in vivo. J. Gen. Physiol. 95:1990;837-866.
37. +] in the hippocampus during recovery from short-term, transient ischemia. J. Cerebral Blood Flow Metab. 12:1992;759-772.
38. Skrede K.K., Westgård R.H. The transverse hippocampal slice: a well-defined cortical structure maintained in vitro. Brain Res. 35:1971;589-593.
39. Takemura H., Hughes A.R., Thastrup O., Putney J.J. Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells: evidence that an intracellular calcium pool and not an inositol phosphate regulates calcium fluxes at the plasma membrane. J. Biol. Chem. 264:1989;12266-12271.
40. i increase activates sodium influx in human platelets. Biochim. Biophys. Acta. 1220:1994;248-252.
41. 2+-ATPase. Proc. Natl. Acad. Sci. USA. 87:1990;2466-2470.
42. Thastrup O., Linnebjerg H., Bjerrum P.J., Knudsen J.B., Christensen S.B. The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations. Biochim. Biophys. Acta. 927:1987;65-73.
43. Verma A., Hirsch D.J., Hanley M.R., Thastrup O., Christensen S.B.et al. Inositol trisphosphate and thapsigargin discriminate endoplasmic reticulum stores of calcium in rat brain. Biochem. Biophys. Res. Commun. 172:1990;811-816.