Overexpression of alpha-ketoglutarate dehydrogenase in Yarrowia lipolytica and its effect on production of organic acids

Applied Microbiology and Biotechnology

Volumn 89, Issue 5, 2011, Pages 1519-1526

  Holz, Martina ^a   Otto, Christina ^a   Kretzschmar, Anne ^a,d   Yovkova, Venelina ^a   Aurich, Andreas ^b   Pötter, Markus ^c   Marx, Achim ^c   Barth, Gerold ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

^c EVONIK DEGUSSA GMBH   (Germany)

^d Wisplinghoff Medical Laboratories   (Germany)

Author keywords

Alpha ketoglutarate dehydrogenase; Alpha ketoglutaric acid; Citric acid; Isocitric acid; Pyruvic acid; Yarrowia lipolytica

Indexed keywords

ALPHA-KETOGLUTARIC ACID; ISOCITRIC ACID; KETOGLUTARATE; PYRUVIC ACID; YARROWIA LIPOLYTICA;

CITRIC ACID; GENES; YEAST;

ORGANIC ACIDS;

2 OXOGLUTARIC ACID; CARBON; CARBOXYLIC ACID; CITRIC ACID; DIHYDROLIPOAMIDE ACETYLTRANSFERASE; DIHYDROLIPOAMIDE DEHYDROGENASE; FUNGAL ENZYME; ISOCITRIC ACID; OXOGLUTARATE DEHYDROGENASE; PROTEIN SUBUNIT; PYRUVIC ACID;

BIOTECHNOLOGY; CITRIC ACID; ENZYME ACTIVITY; YEAST;

ACID SECRETION; ARTICLE; CARBON SOURCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SYNTHESIS; FUNGAL GENE; FUNGAL STRAIN; FUNGUS GROWTH; GENE DOSAGE; GENE EXPRESSION; GENE OVEREXPRESSION; NONHUMAN; SACCHAROMYCES CEREVISIAE; WILD TYPE; YARROWIA LIPOLYTICA;

CARBOXYLIC ACIDS; GENE EXPRESSION; KETOGLUTARATE DEHYDROGENASE COMPLEX; RECOMBINANT PROTEINS; YARROWIA;

SACCHAROMYCES CEREVISIAE; YARROWIA LIPOLYTICA;

EID: 79952574205     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-010-2957-9     Document Type: Article

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