Breeding of high-pyruvate-producing Torulopsis glabrata with acquired reduced pyruvate decarboxylase

Journal of Bioscience and Bioengineering

Volumn 88, Issue 2, 1999, Pages 173-177

  Miyata, Reiko ^a   Yonehara, Tetsu ^a  

^a TORAY INDUSTRIES INC   (Japan)

Author keywords

Acetate leaky auxotroph; Pyruvate decarboxylase (PDC); Pyruvic acid fermentation; Torulopsis glabrata

Indexed keywords

ACETALDEHYDE; ACETIC ACID; GLUCOSE; PYRUVATE DECARBOXYLASE; PYRUVIC ACID;

AMINO ACID SYNTHESIS; ANIMAL CELL; ARTICLE; BREEDING; CONTROLLED STUDY; ENZYME ACTIVITY; FERMENTATION; FUNGUS GROWTH; MUTAGENESIS; NONHUMAN; TORULOPSIS GLABRATA;

ANIMALIA; CANDIDA GLABRATA; FUNGI; TORULOPSIS; TORULOPSIS GLABRATA;

EID: 0032825966     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1389-1723(99)80197-2     Document Type: Article

References (9)

1. 1. Yonehara, T. and Miyata, R.: Pyruvic acid production from glucose by Torulopsis glabrata. J. Ferment. Bioeng., 78, 155-159 (1994).
2. 2. Miyata, R. and Yonehara, T.: Improvement of fermentative production of pyruvate from glucose by Torulopsis glabrata IFO 0005. J. Ferment. Bioeng., 82, 475-479 (1996).
3. 3. O'Connor, M. L. and Quayle, J. R.: Mutants of Hansenula polymorpha and Candida boidinii impaired in their ability to grow on methanol. J. Gen. Microbiol., 113, 203-208 (1979).
4. 4. Holzer, H. and Goedde, W. H.: Zwei wege von Pyruvate zu acetyl-Coenzyme A in Hefe. Biochem. Z., 329, 175-191 (1957).
5. 5. Plolakis, E. S. and Bartley, W.: Changes in the enzyme activities of Saccharomyces cerevisiae during aerobic growth of yeast on different carbon sources. Biochem. J., 97, 284-297 (1965).
6. 6. Sharma S. and Tauro, P.: Control of ethanol production by yeast: role of pyruvate decarboxylase and alcohol dehydrogenase. Biotechnol. Lett., 8, 735-738 (1986).
7. 7. Peter, G. S., Klaus, B., and Cornelis, P. H.: pdcl° mutants of Saccharomyces cerevisiae give evidence for an additional structural PDC gene: cloning of PDC5, a gene homologous to PDC1. J. Bacteriol., 172(2), 678-685 (1990).
8. 8. Marcel, T. F., Linda, V. D. Z., Wouter, et al.: Pyruvate decarboxylase: an indispensable enzyme for growth of Saccharomyces cerevisiae on glucose. Yeast, 12, 247-257 (1996).
9. 9. Ping, L., Brian, P. D., and Thomas, W. J.: Cloning and characterization of two pyruvate decarboxylase genes from Pichia stipitis CBS 6054. Appl. Environ. Microbiol., 63, 3399-3404 (1997).