Effect of alcohol consumption on whole-body protein turnover in healthy adults

Isotopes in Environmental and Health Studies

Volumn 47, Issue 1, 2011, Pages 26-33

  Wutzke, Klaus D ^a   Krentz, Helga ^a   Bruns, Gerrit ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

15N labelled yeast protein; Alcohol; Health; Human; Isotope application in medicine; Liver function; Nitrogen 15; Whole body protein turnover

Indexed keywords

ALCOHOL; DIAGNOSTIC AGENT; NITROGEN; PROTEIN;

ADULT; DIET; FOOD CONSUMPTION; HEALTH STATUS; ISOTOPIC RATIO; MASS SPECTROMETRY; PROTEIN;

ADULT; ARTICLE; DRINKING BEHAVIOR; DRUG EFFECT; FEMALE; GERMANY; HUMAN; MALE; MASS SPECTROMETRY; METABOLISM; OXIDATIVE STRESS; SACCHAROMYCES CEREVISIAE; WINE;

ADULT; ALCOHOL DRINKING; ETHANOL; FEMALE; GERMANY; HUMANS; MALE; MASS SPECTROMETRY; NITROGEN ISOTOPES; OXIDATIVE STRESS; PROTEINS; SACCHAROMYCES CEREVISIAE; WINE; YOUNG ADULT;

EID: 79952527127     PISSN: 10256016     EISSN: 14772639     Source Type: Journal    
DOI: 10.1080/10256016.2011.557724     Document Type: Article

References (37)

1. K.D. Wutzke, A. Forberger, and M. Wigger, Effect of Alcohol Consumption on the Liver Detoxication Capacity as Measured by [13C]Methacetin- and [Methyl-13C]Methionine-Breath Tests, Isot. Environ. Health Stud. 44, 219 (2008).
2. K.D. Wutzke and M. Wigger, Effect of Alcohol Consumption on the Liver Detoxication Capacity as Measured by [13C2]Aminopyrine and l-[1-13C]Phenylalanine Breath Tests, Isot. Environ. Health Stud. 45, 185 (2009).
3. F. Mion, P.E. Queneau, M. Rousseau, J.L. Brazier, P. Paliard, andY. Minaire,Aminopyrine Breath Test: Development of a 13C-Breath Test for Quantitative Assessment of Liver Function in Humans, Hepatogastroenterology 42, 931 (1995).
4. S. Lara Baruque, M. Razquin, I. Jimenez, A. Vazquez, J.P. Gisbert, and J.M. Pajares, 13C-Phenylalanine and 13CMethacetin Breath Test to Evaluate Functional Capacity of Hepatocyte in Chronic Liver Disease, Dig. Liver Dis. 32, 226 (2000).
5. C. Di Campli, G. Angelini, A. Armuzzi, B. Nardo, M.A. Zocco, M. Candelli, A. Santoliquido, A. Cavallari, M. Bernardi, and A. Gasbarrini, Quantitative Evaluation of Liver Function by the Methionine and Aminopyrine Breath Tests in the Early Stages of Liver Transplantation, Eur. J. Gastroenterol. Hepatol. 15, 727 (2003).
6. M. Candelli, I.A. Cazzato, M.A. Zocco, E.C. Nista, L. Fini, A. Armuzzi, V. Camise, M. Santoro, L. Miele, A. Grieco, G. Gasbarrini, and A. Gasbarrini, 13C-Breath Tests in the Study of Mitochondrial Liver Function, Eur. Rev. Med. Pharmacol. Sci. 8, 23 (2004).
7. E.C. Nista, L. Fini, A. Armuzzi, M. Candelli, M.A. Zocco, I.A. Cazzato, G. Merra, R. Finizio, L. Miele, A. Grieco, G. Gasbarrini, and A. Gasbarrini, 13C-Breath Tests in the Study of Microsomal Liver Function, Eur. Rev. Med. Pharmacol. Sci. 8, 33 (2004).
8. D. Festi, S. Capodicasa, L. Sandri, L. Colaiocco-Ferrante, T. Staniscia, E. Vitacolonna, A. Vestito, P. Simoni, G. Mazzella, P. Portincasa, E. Roda, and A. Colecchia, Measurement of Hepatic Functional Mass by Means of 13CMethacetin and 13C-Phenylalanine Breath Tests in Chronic Liver Disease: Comparison with Child-Pugh Score and Serum Bile Acid Levels, World J. Gastroenterol. 11, 142 (2005).
9. W. Heine, I. Richter, C. Plath, K. Wutzke, F. Oswald, S. Oswald, and J. Töwe, Evaluation of Different 15N-Tracer Substances for Calculation of Whole Body Protein Parameters in Infants, J. Pediatr. Gastroenterol. Nutr. 2, 599 (1983).
10. K. Wutzke, W. Heine, U. Drescher, I. Richter, and C. Plath, 15N-Labelled Yeast Protein - A Valid Tracer for Calculating Whole-Body Protein Parameters in Infants: A Comparison Between [15N]-Yeast Protein and [15N]- Glycine, Hum. Nutr. Clin. Nutr. 37, 317 (1983).
11. K.D. Wutzke, W. Heine, T. Völker, F. Kreyenbrink, and K. Krawielitzki, Präparative Darstellung von hochangereichertem 15N-markiertem Hefeprotein, Isotopenpraxis 20, 90 (1984).
12. K.D. Wutzke, W. Heine, C. Plath, M. Müller, and M. Uhlemann, Whole-Body Protein Parameters in Premature Infants: A Comparison of Different 15N Tracer Substances and Different Methods, Pediatr. Res. 31, 95 (1992).
13. C.W. Crane and A. Neuberger, The Digestion and Absorption of Protein by Normal Man, Biochem. J. 74, 313 (1960).
14. C.W. Crane and A. Neuberger, Absorption and Elimination of 15N after Administration of Isotopically Labelled Yeast Protein andYeast Protein Hydrolysate to Adult Patients with Coeliac Disease. 2. Elimination of Isotope in the Urine and Faeces, Br. Med. J. 2, 888 (1960).
15. K.D. Wutzke, M. Lotz, and C. Zipprich, The Effect of Pre- and Probiotics on the Colonic Ammonia Metabolism in Humans as Measured by Lactose-[15N2]Ureide, Eur. J. Clin. Nutr. 64, 1215 (2010).
16. A. Barrie, J.E. Davies, A.J. Park, and C.T. Workmann, Continuous-Flow Stable Isotope Analysis for Biologists, Spectroscopy 4, 42 (1989).
17. K.D. Wutzke, W.E. Heine, D. Köster, J. Muscheites, M. Mix, C. Mohr, K. Popp, and M. Wigger, Metabolic Effects of HAY's Diet, Isot. Environ. Health Stud. 37, 227 (2001).
18. K.D. Wutzke and H. Lorenz, The Effect of l-Carnitine on Fat Oxidation, Protein turnover and Body Composition in Slightly Overweight Subjects, Metabolism 53, 1002 (2004).
19. M. Wigger and K.D. Wutzke, Whole-Body Protein Turnover in Nephrotic Subjects: A Comparison Between Different Degrees of Proteinuria, Isot. Environ. Health Stud. 40, 155 (2004).
20. D. Picou and T. Taylor-Roberts, The Measurement of Total Protein Synthesis and Catabolism and Nitrogen Turnover in Infants in Different Nutritional States and Receiving Different Amounts of Dietary Protein, Clin. Sci. 36, 283 (1969).
21. J.C. Waterlow, M.H.N. Golden, and P.J. Garlick, Protein Turnover in Man Measured with 15N: Comparison of End Products and Dose Regimes, Am. J. Physiol. 235, E165 (1978).
22. J.C. Waterlow and A.A. Jackson, Nutrition and Protein Turnover in Man, Br. Med. Bull. 37, 5 (1981).
23. M.H.N. Golden and A.A. Jackson, Assumptions and Errors in the Use of 15N-Excretion Data to Estimate Whole- Body Protein Turnover, in Nitrogen Metabolism in Man, edited by J.C. Waterlow and J.M.L. Stephen (Applied Science Publishers, London, 1981), pp. 323-344.
24. E.B. Fern, P.J. Garlick, and J.C. Waterlow, Apparent Compartmentation of Body Nitrogen in One Human Subject: Its Consequences in Measuring the Rate of Whole-Body Protein Synthesis with 15N, Clin. Sci. 68, 271 (1985).
25. D.M. Bier V.R. Young, Assessment of Whole-Body Protein-Nitrogen Kinetics in the Human Infant, in Energy and Protein Needs During Infancy, edited by S.J. Fomon and W.C. Heird (Academic Press, Orlando, FL, 1986), pp. 107-125.
26. V.R. Young, A.E. El-Khoury, M. Sanchez, and L. Castillo, The Biochemistry and Physiology of Protein and Amino Acid Metabolism, with Reference to Protein Nutrition, in Protein Metabolism During Infancy, edited by N.C.R. Räihä (Nestlé NutritionWorkshop Series, Nestec, Raven Press, NewYork, NY, 1994), Vol. 33, pp. 1-28.
27. D.E. Matthews, J.M. Conway, V.R. Young, and D.M. Bier, Glycine Nitrogen Metabolism in Man, Metabolism 30, 886 (1981).
28. A.A. Jackson, The Glycine Story, Eur. J. Clin. Nutr. 45, 59 (1991).
29. K.D. Wutzke, D.E. Matthews, W. Heine, 15N-Markierung von Plasmaaminosäuren nach oraler Applikation von [15N]Glycin, [15N]Leucin und [15N]Hefeprotein-Thermitase Hydrolysat, Isotopenpraxis 28, 36 (1992).
30. P.J. Garlick, G.A. Clugston, and J.C. Waterlow, Influence of Low-Energy Diets on Whole-Body Protein Turnover in Obese Subjects, Am. J. Physiol. 238, E235 (1980).
31. M.H.N. Golden, J.C. Waterlow, and D. Picou, Metabolism of 15N Nucleic Acids in Children, in Nitrogen Metabolism in Man, edited by J.C.Waterlow and J.M.L. Stephen (Applied Science Publishers, London, 1981), pp. 269-273.
32. 15N]-Wheat, Hum. Nutr. Clin. Nutr. 37, 91 (1983).
33. 15N]-Yeast Protein Thermitase Hydrolysate: Development of a New 15N-Tracer Substance, in Recent Advances in Infant Feeding, edited by B. Koletzko, A. Okken, J. Rey, B. Salle, and J.P. Van Biervliet (Georg Thieme, Stuttgart, NewYork, NY, 1992), pp. 123-132.
34. P.J. Pacy, V.R. Preedy, T.J. Peters, M. Read, and D. Halliday, The Effect of Chronic Alcohol Ingestion on Whole Body and Muscle Protein Synthesis -A Stable Isotope Study, Alcohol Alcohol. 26, 505 (1991).
35. W.L. Morrison, I.A. Bouchier, J.N. Gibson, and M.J. Rennie, Skeletal Muscle and Whole-Body Protein Turnover in Cirrhosis, Clin. Sci. 78, 613 (1990).
36. I.M. Nakshabendi, S. Downie, R.I. Russell, and M.J. Rennie, Small-Intestinal Mucosal Protein Synthesis and Whole- Body Protein Turnover in Alcoholic Liver Disease, Clin. Sci. 97, 633 (1999).
37. J.B. Dichi, I. Dichi, R. Maio, C.R. Correa, A.Y. Angeleli, M.H. Bicudo, T.A. Rezende, and R.C. Burini, Whole-body Protein Turnover in Malnourished Patients with Child Class B and C Cirrhosis on Diets Low to High in Protein Energy, Nutrition 17, 239 (2001).