Validation of individual quantitative methods for determination of cytochrome P450 probe substrates in human dried blood spots with HPLC-MS/MS

Bioanalysis

Volumn 2, Issue 11, 2010, Pages 1849-1861

  Lad, Rakesh ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CYTOCHROME P450; FLURBIPROFEN; METHANOL; MIDAZOLAM; OMEPRAZOLE; ROSIGLITAZONE;

ACCURACY; ANALYTICAL EQUIPMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRIED BLOOD SPOT SAMPLING; DRUG STABILITY; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; MASS SPECTROMETRY; PHYSICAL CHEMISTRY; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS; BLOOD ANALYSIS; DESICCATION; ENZYME SPECIFICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; METHODOLOGY; STATISTICAL MODEL; VALIDATION STUDY;

BLOOD CHEMICAL ANALYSIS; BLOOD SPECIMEN COLLECTION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DESICCATION; DRUG STABILITY; HUMANS; LINEAR MODELS; SUBSTRATE SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 79952511858     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.10.155     Document Type: Article

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