-
1
-
-
58249088751
-
MicroRNAs: target recognition and regulatory functions
-
Bartel DP, (2009) MicroRNAs: target recognition and regulatory functions. Cell 136: 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
2
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V, (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
3
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
-
Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, et al. (2000) The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403: 901-906.
-
(2000)
Nature
, vol.403
, pp. 901-906
-
-
Reinhart, B.J.1
Slack, F.J.2
Basson, M.3
Pasquinelli, A.E.4
Bettinger, J.C.5
-
4
-
-
33645124258
-
Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs
-
Giraldez AJ, Mishima Y, Rihel J, Grocock RJ, Van Dongen S, et al. (2006) Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science 312: 75-79.
-
(2006)
Science
, vol.312
, pp. 75-79
-
-
Giraldez, A.J.1
Mishima, Y.2
Rihel, J.3
Grocock, R.J.4
Van Dongen, S.5
-
5
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435: 834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
-
6
-
-
77951474125
-
Target mRNA abundance dilutes microRNA and siRNA activity
-
Arvey A, Larsson E, Sander C, Leslie CS, Marks DS, (2010) Target mRNA abundance dilutes microRNA and siRNA activity. Mol Syst Biol 6: 363.
-
(2010)
Mol Syst Biol
, vol.6
, pp. 363
-
-
Arvey, A.1
Larsson, E.2
Sander, C.3
Leslie, C.S.4
Marks, D.S.5
-
8
-
-
38549124383
-
The microRNA.org resource: targets and expression
-
Betel D, Wilson M, Gabow A, Marks DS, Sander C, (2008) The microRNA.org resource: targets and expression. Nucleic Acids Res 36: D149-153.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Betel, D.1
Wilson, M.2
Gabow, A.3
Marks, D.S.4
Sander, C.5
-
9
-
-
20944450160
-
Combinatorial microRNA target predictions
-
Krek A, Grun D, Poy MN, Wolf R, Rosenberg L, et al. (2005) Combinatorial microRNA target predictions. Nat Genet 37: 495-500.
-
(2005)
Nat Genet
, vol.37
, pp. 495-500
-
-
Krek, A.1
Grun, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
-
10
-
-
34748821761
-
The role of site accessibility in microRNA target recognition
-
Kertesz M, Iovino N, Unnerstall U, Gaul U, Segal E, (2007) The role of site accessibility in microRNA target recognition. Nat Genet 39: 1278-1284.
-
(2007)
Nat Genet
, vol.39
, pp. 1278-1284
-
-
Kertesz, M.1
Iovino, N.2
Unnerstall, U.3
Gaul, U.4
Segal, E.5
-
11
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
Friedman RC, Farh KK, Burge CB, Bartel DP, (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19: 92-105.
-
(2009)
Genome Res
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
Bartel, D.P.4
-
12
-
-
57749206034
-
Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex
-
Wang Y, Juranek S, Li H, Sheng G, Tuschl T, et al. (2008) Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature 456: 921-926.
-
(2008)
Nature
, vol.456
, pp. 921-926
-
-
Wang, Y.1
Juranek, S.2
Li, H.3
Sheng, G.4
Tuschl, T.5
-
13
-
-
15244354492
-
Incorporating structure to predict microRNA targets
-
Robins H, Li Y, Padgett RW, (2005) Incorporating structure to predict microRNA targets. Proc Natl Acad Sci U S A 102: 4006-4009.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 4006-4009
-
-
Robins, H.1
Li, Y.2
Padgett, R.W.3
-
14
-
-
34247258888
-
Potent effect of target structure on microRNA function
-
Long D, Lee R, Williams P, Chan CY, Ambros V, et al. (2007) Potent effect of target structure on microRNA function. Nat Struct Mol Biol 14: 287-294.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 287-294
-
-
Long, D.1
Lee, R.2
Williams, P.3
Chan, C.Y.4
Ambros, V.5
-
15
-
-
34447102459
-
Molecular basis for target RNA recognition and cleavage by human RISC
-
Ameres SL, Martinez J, Schroeder R, (2007) Molecular basis for target RNA recognition and cleavage by human RISC. Cell 130: 101-112.
-
(2007)
Cell
, vol.130
, pp. 101-112
-
-
Ameres, S.L.1
Martinez, J.2
Schroeder, R.3
-
16
-
-
33646877072
-
Thermodynamics of RNA-RNA binding
-
Mückstein U, Tafer H, Hackermuller J, Bernhart SH, Stadler PF, et al. (2006) Thermodynamics of RNA-RNA binding. Bioinformatics 22: 1177-1182.
-
(2006)
Bioinformatics
, vol.22
, pp. 1177-1182
-
-
Mückstein, U.1
Tafer, H.2
Hackermuller, J.3
Bernhart, S.H.4
Stadler, P.F.5
-
17
-
-
66749109861
-
Transcriptome-wide prediction of miRNA targets in human and mouse using FASTH
-
Ragan C, Cloonan N, Grimmond SM, Zuker M, Ragan MA, (2009) Transcriptome-wide prediction of miRNA targets in human and mouse using FASTH. PLoS One 4: e5745.
-
(2009)
PLoS One
, vol.4
-
-
Ragan, C.1
Cloonan, N.2
Grimmond, S.M.3
Zuker, M.4
Ragan, M.A.5
-
18
-
-
84934438960
-
UNAFold: software for nucleic acid folding and hybridization
-
Markham NR, Zuker M, (2008) UNAFold: software for nucleic acid folding and hybridization. Methods Mol Biol 453: 3-31.
-
(2008)
Methods Mol Biol
, vol.453
, pp. 3-31
-
-
Markham, N.R.1
Zuker, M.2
-
19
-
-
0033591465
-
Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
-
Mathews DH, Sabina J, Zuker M, Turner DH, (1999) Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J Mol Biol 288: 911-940.
-
(1999)
J Mol Biol
, vol.288
, pp. 911-940
-
-
Mathews, D.H.1
Sabina, J.2
Zuker, M.3
Turner, D.H.4
-
20
-
-
45249120816
-
Modelling and measuring single cell RNA expression levels find considerable transcriptional differences among phenotypically identical cells
-
Subkhankulova T, Gilchrist MJ, Livesey FJ, (2008) Modelling and measuring single cell RNA expression levels find considerable transcriptional differences among phenotypically identical cells. BMC Genomics 9: 268.
-
(2008)
BMC Genomics
, vol.9
, pp. 268
-
-
Subkhankulova, T.1
Gilchrist, M.J.2
Livesey, F.J.3
-
21
-
-
34347376692
-
Characterization of microRNA expression profiles in normal human tissues
-
Liang Y, Ridzon D, Wong L, Chen C, (2007) Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 8: 166.
-
(2007)
BMC Genomics
, vol.8
, pp. 166
-
-
Liang, Y.1
Ridzon, D.2
Wong, L.3
Chen, C.4
-
22
-
-
0842321501
-
MicroRNA targets in Drosophila
-
Enright AJ, John B, Gaul U, Tuschl T, Sander C, et al. (2003) MicroRNA targets in Drosophila. Genome Biol 5: R1.
-
(2003)
Genome Biol
, vol.5
-
-
Enright, A.J.1
John, B.2
Gaul, U.3
Tuschl, T.4
Sander, C.5
-
23
-
-
27344456287
-
microRNA target predictions across seven Drosophila species and comparison to mammalian targets
-
Grun D, Wang YL, Langenberger D, Gunsalus KC, Rajewsky N, (2005) microRNA target predictions across seven Drosophila species and comparison to mammalian targets. PLoS Comput Biol 1: e13.
-
(2005)
PLoS Comput Biol
, vol.1
-
-
Grun, D.1
Wang, Y.L.2
Langenberger, D.3
Gunsalus, K.C.4
Rajewsky, N.5
-
25
-
-
54249136806
-
MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
-
Papagiannakopoulos T, Shapiro A, Kosik KS, (2008) MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res 68: 8164-8172.
-
(2008)
Cancer Res
, vol.68
, pp. 8164-8172
-
-
Papagiannakopoulos, T.1
Shapiro, A.2
Kosik, K.S.3
-
26
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, et al. (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A 103: 2257-2261.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
-
27
-
-
70349741005
-
A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis
-
Sætrom P, Biesinger J, Li SM, Smith D, Thomas LF, et al. (2009) A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis. Cancer Res 69: 7459-7465.
-
(2009)
Cancer Res
, vol.69
, pp. 7459-7465
-
-
Sætrom, P.1
Biesinger, J.2
Li, S.M.3
Smith, D.4
Thomas, L.F.5
-
28
-
-
49949116902
-
The impact of microRNAs on protein output
-
Baek D, Villen J, Shin C, Camargo FD, Gygi SP, et al. (2008) The impact of microRNAs on protein output. Nature 455: 64-71.
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villen, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
-
29
-
-
49949117302
-
Widespread changes in protein synthesis induced by microRNAs
-
Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, et al. (2008) Widespread changes in protein synthesis induced by microRNAs. Nature 455: 58-63.
-
(2008)
Nature
, vol.455
, pp. 58-63
-
-
Selbach, M.1
Schwanhausser, B.2
Thierfelder, N.3
Fang, Z.4
Khanin, R.5
-
30
-
-
77950920903
-
Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP
-
Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, et al. (2010) Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell 141: 129-141.
-
(2010)
Cell
, vol.141
, pp. 129-141
-
-
Hafner, M.1
Landthaler, M.2
Burger, L.3
Khorshid, M.4
Hausser, J.5
-
31
-
-
34250805982
-
MicroRNA targeting specificity in mammals: determinants beyond seed pairing
-
Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, et al. (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 27: 91-105.
-
(2007)
Mol Cell
, vol.27
, pp. 91-105
-
-
Grimson, A.1
Farh, K.K.2
Johnston, W.K.3
Garrett-Engele, P.4
Lim, L.P.5
-
32
-
-
34249856066
-
Distance constraints between microRNA target sites dictate efficacy and cooperativity
-
Sætrom P, Heale BS, Snøve O Jr, Aagaard L, Alluin J, et al. (2007) Distance constraints between microRNA target sites dictate efficacy and cooperativity. Nucleic Acids Res 35: 2333-2342.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 2333-2342
-
-
Sætrom, P.1
Heale, B.S.2
Snøve Jr., O.3
Aagaard, L.4
Alluin, J.5
-
33
-
-
67149115119
-
Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
-
Khan AA, Betel D, Miller ML, Sander C, Leslie CS, et al. (2009) Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. Nat Biotechnol 27: 549-555.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 549-555
-
-
Khan, A.A.1
Betel, D.2
Miller, M.L.3
Sander, C.4
Leslie, C.S.5
-
34
-
-
76749129681
-
Self-complementary sequence context in mature miRNAs
-
Maiti M, Nauwelaerts K, Lescrinier E, Schuit FC, Herdewijn P, (2010) Self-complementary sequence context in mature miRNAs. Biochem Biophys Res Commun 392: 572-576.
-
(2010)
Biochem Biophys Res Commun
, vol.392
, pp. 572-576
-
-
Maiti, M.1
Nauwelaerts, K.2
Lescrinier, E.3
Schuit, F.C.4
Herdewijn, P.5
-
35
-
-
27944473306
-
Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency
-
Patzel V, Rutz S, Dietrich I, Koberle C, Scheffold A, et al. (2005) Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency. Nat Biotechnol 23: 1440-1444.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1440-1444
-
-
Patzel, V.1
Rutz, S.2
Dietrich, I.3
Koberle, C.4
Scheffold, A.5
-
36
-
-
36849060584
-
Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state
-
Brown BD, Gentner B, Cantore A, Colleoni S, Amendola M, et al. (2007) Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state. Nat Biotechnol 25: 1457-1467.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 1457-1467
-
-
Brown, B.D.1
Gentner, B.2
Cantore, A.3
Colleoni, S.4
Amendola, M.5
-
37
-
-
33644750115
-
miRBase: microRNA sequences, targets and gene nomenclature
-
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ, (2006) miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 34: D140-144.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Griffiths-Jones, S.1
Grocock, R.J.2
van Dongen, S.3
Bateman, A.4
Enright, A.J.5
-
38
-
-
3042735602
-
Prediction of hybridization and melting for double-stranded nucleic acids
-
Dimitrov RA, Zuker M, (2004) Prediction of hybridization and melting for double-stranded nucleic acids. Biophys J 87: 215-226.
-
(2004)
Biophys J
, vol.87
, pp. 215-226
-
-
Dimitrov, R.A.1
Zuker, M.2
-
39
-
-
13344279384
-
Evaluation of the suitability of free-energy minimization using nearest-neighbor energy parameters for RNA secondary structure prediction
-
Doshi KJ, Cannone JJ, Cobaugh CW, Gutell RR, (2004) Evaluation of the suitability of free-energy minimization using nearest-neighbor energy parameters for RNA secondary structure prediction. BMC Bioinformatics 5: 105.
-
(2004)
BMC Bioinformatics
, vol.5
, pp. 105
-
-
Doshi, K.J.1
Cannone, J.J.2
Cobaugh, C.W.3
Gutell, R.R.4
-
40
-
-
39149106448
-
Efficient siRNA selection using hybridization thermodynamics
-
Lu ZJ, Mathews DH, (2008) Efficient siRNA selection using hybridization thermodynamics. Nucl Acids Res 36: 640-647.
-
(2008)
Nucl Acids Res
, vol.36
, pp. 640-647
-
-
Lu, Z.J.1
Mathews, D.H.2
|