The effect of regular exercise on development of sarcoma tumor and oxidative damage in mice liver

Journal of Sports Science and Medicine

Volumn 10, Issue 1, 2011, Pages 93-96

  Sasvari, Maria ^a   Taylor, Albert W ^b   Gaal, Dezso ^c   Radak, Zsolt ^a  

^a UNIVERSITY OF PHYSICAL EDUCATION   (Hungary)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c NATIONAL INSTITUTE OF ONCOLOGY   (Hungary)

Author keywords

Cancer; DNA damage; Exercise; Oxidative stress; Reactive carbonyl derivatives

Indexed keywords

EID: 79952472749     PISSN: None     EISSN: 13032968     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Daneryd, P., Aberg, F., Dallner, G., Ernster, L., Schersten, T. and Soussi, B. (1995a) Coenzymes Q9 and Q10 in skeletal and cardiac muscle in tumour-bearing exercising rats. European Journal of Cancer 31A, 760-765.
2. Daneryd, P., Hafstrom, L., Svanberg, E. and Karlberg, I. (1995b) Insulin sensitivity, hormonal levels and skeletal muscle protein metabolism in tumour-bearing exercising rats. European Journal of Cancer 31A, 97-103.
3. Davies, K.J., Quintanilha, A.T., Brooks, G.A. and Packer, L. (1982) Free radicals and tissue damage produced by exercise. Biochemical Biophysical Researcg Communication 107, 1198-1205.
4. Fairey, A.S., Courneya, K.S., Field, C.J. and Mackey, J.R. (2002) Physical exercise and immune system function in cancer survivors: a comprehensive review and future directions. Cancer 94, 539-551.
5. Finlay, C. A., Hinds, P. W. and Levine, A. J. (1989) The p53 protooncogene can act as a suppressor of transformation. Cell 57, 1083-1093.
6. Foster, B.A., Coffey, H.A., Morin, M.J. and Rastinejad, F. (1999) Pharmacological rescue of mutant p53 conformation and function. Science 286, 2507-2510.
7. Gerber, M. (2000) Oxidative stress, antioxidants and cancer. In: Handbook of Oxidants and Antioxidants in Exercise. Eds: Sen, C.K, L. Packer, L. and Hanninen, O. Amsterdam: Elsevier Sci. 927-949.
8. Hill, M.J. (1999) Diet, physical activity and cancer risk. Public Health Nutrition 2, 397-401.
9. Inger, T. and Eiliv, L. (1997) Exercise and breast cancer. New England Journal of Medicine 337, 708-709.
10. Ji, L.L. (1999) Antioxidants and oxidative stress in exercise. Proceeding Society Experimental Biology and Medicine 222, 283-292.
11. Ji, L.L. and Hollander, J. (2000) Antioxidant enzyme defense: effects of aging and exercise. In: Free Radicals in Exercise and Aging. Ed: Radak, Z. Champaign, IL.: Human Kinetics. 35-72.
12. Kaelin, W.G., Jr. (1999) The p53 gene family. Oncogene 18, 7701-7705.
13. Kiningham, R.B. (1998) Physical activity and the primary prevention of cancer. Primary Care 25, 515-536.
14. Kritchevsky, D. (2001) Caloric restriction and cancer. Journal of Nutrition Science and Vitaminology (Tokyo) 47, 13-19.
15. Lane, D.P. and Benchimol, S. (1990) p53: oncogene or anti-oncogene? Genes Dev 4, 1-8.
16. Murphy, K.L., Dennis, A.P. and Rosen, J.M. (2000) A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53-null mammary epithelial cell model. FASEB Journal 14, 2291-2302.
17. Oren, M. (1992) p53: the ultimate tumor suppressor gene? FASEB Journal 6, 3169-3176.
18. Radak, Z., Asano, K., Lee, K. C., Ohno, H., Nakamura, A., Nakamoto, H. and Goto, S. (1997) High altitude training increases reactive carbonyl derivatives but not lipid peroxidation in skeletal muscle of rats. Free Radical Biology and Medicine 22, 1109-1114.
19. Radak, Z. and Goto, S. (2000) Oxidative modification of proteins and DNA. In: Free Radicals in Exercise and Aging. Ed: Radak, Z. Champaign, IL.: Human Kinetics. 177-210.
20. Radak, Z., Kaneko, T., Tahara, S., Nakamoto, H., Ohno, H., Sasvari, M., Nyakas, C. and Goto, S. (1999) The effect of exercise training on oxidative damage of lipids, proteins, and DNA in rat skeletal muscle: evidence for beneficial outcomes. Free Radical Biology and Medicine 27, 69-74.
21. Radak, Z., Taylor, A. W., Sasvari, M., Ohno, H., Horkay, B., Furesz, J., Gaal, D. and Kanel, T. (2001) Telomerase activity is not altered by regular strenuous exercise in skeletal muscle or by sarcoma in liver of rats. Redox Report 6, 99-103.
22. Shephard, R.J. and Futcher, R. (1997) Physical activity and cancer: how may protection be maximized? Critcal Review of Oncogolgy 8, 219-272.
23. Thompson, H.J. (1994) Effect of exercise intensity and duration on the induction of mammary carcinogenesis. Cancer Research 54, 1960s-1963s.
24. Thompson, H.J., Westerlind, K. C., Snedden, J., Briggs, S. and Singh, M. (1995) Exercise intensity dependent inhibition of 1-methyl-1-nitrosourea induced mammary carcinogenesis in female F- 344 rats. Carcinogenesis 16, 1783-1786.
25. Tomayko, M.M. and Reynolds, C.P. (1989) Determination of subcutaneous tumor size in athymic (nude) mice. Cancer Chemotherapy and Pharmacology 24, 148-154.
26. Wiedmann, M.W. and Caca, K. (2005) Molecularly targeted therapy for gastrointestinal cancer. Current Cancer Drug Targets 5, 171-193.
27. Wiedmann, M.W. and Mossner, J. (2010) Molecular targeted therapy of biliary tract cancer--results of the first clinical studies. Current Cancer Drug Targets 11, 834-850.
28. Zhang, Z., Li, J., Lantry, L.E., Wang, Y., Wiseman, R.W., Lubet, R.A. and You, M. (2002) p53 transgenic mice are highly susceptible to 1, 2-dimethylhydrazine-induced uterine sarcomas. Cancer Research 62, 3024-3029.