A practical synthesis of 2-aroylindoles from N-(2-formylphenyl)trifluoro- acetamides in PEG-400

Synthesis

Volumn , Issue 6, 2011, Pages 873-880

  Zhao, Yu ^a   Li, Deyao ^a   Zhao, Liwen ^a   Zhang, Jiancun ^a,b  

^a GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

2 aroylindoles; cyclization; heterocycles; N (2 formylphenyl)trifluoro acetamides; PEG 400

Indexed keywords

2-AROYLINDOLES; ENVIRONMENTALLY BENIGN; FUNCTIONALIZED; GOOD YIELD; HETEROCYCLES; N -(2-FORMYLPHENYL)TRIFLUORO-ACETAMIDES; ONE POT; PEG-400; TRIFLUOROACETAMIDES;

SYNTHESIS (CHEMICAL);

CYCLIZATION;

(1H INDOL 2 YL) (2 METHOXYPHENYL)METHANONE; (1H INDOL 2 YL) (3 METHOXYPHENYL)METHANONE; (1H INDOL 2 YL) (4 METHYLPHENYL)METHANONE; (1H INDOL 2 YL) (4 NITROPHENYL)METHANONE; (1H INDOL 2 YL) (NAPHTHALENE 2 YL)METHANONE; (1H INDOL 2 YL)(PHENYL)METHANONE; (1H INDOL 2 YL)(THIOPHEN 2 YL)METHANONE; (2 BROMOPHENYL) (1H INDOL 2 YL)METHANONE; (4 CHLOROPHENYL) (1H INDOL 2 YL)METHANONE; (4 FLUOROPHENYL) (1H INDOL 2 YL)METHANONE; (5,6 DIMETHOXY 1H INDOL 2 YL)(PHENYL)METHANONE; (6 CHLORO 1H INDOL 2 YL)(PHENYL)METHANONE; (FURAN 2 YL) (1H INDOL 2 YL)METHANONE; 2 ACETYLINDOLE; 2 AROYLINDOLE DERIVATIVE; 2,2,2 TRIFLUORO N (2 FORMYL 4,5 DIMETHOXYPHENYL)ACETAMIDE; 2,2,2 TRIFLUORO N (2 FORMYLPHENYL)ACETAMIDE; 2,2,2 TRIFLUORO N (6 FORMYLBENZO[D] [1,3]DIOXOL 5 YL)ACETAMIDE; 4 BROMOPHENACYL BROMIDE; [5 (BENZYLOXY) 1H INDOL 2 YL](PHENYL)METHANONE; [5H [1,3]DIOXOLO [4,5 F]INDO 6 YL](PHENYL)METHANONE; INDOLE DERIVATIVE; MACROGOL 400; METHYL 2 (PHENYLCARBONYL) 1H INDOLE 6 CARBOXYLATE; METHYL 4 FORMYL 3 (2,2,2 TRIFLUOROACETAMIDO)BENZOATE; N (2 FORMYLPHENYL)TRIFLUOROACETAMIDE DERIVATIVE; N (5 CHLORO 2 FORMYLPHENYL) 2,2,2 TRIFLUOROACETAMIDE; N [4 (BENZYLOXY) 2 FORMYLPHENYL] 2,2,2 TRIFLUOROACETAMIDE; TRIFLUOROACETAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; CYCLIZATION; FEASIBILITY STUDY; ONE POT SYNTHESIS; PROCESS OPTIMIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION TIME; TEMPERATURE;

EID: 79952450496     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0030-1258445     Document Type: Article

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