Corticosteroids modulate angiogenic soluble factors in ulcerative colitis patients

Digestive Diseases and Sciences

Volumn 56, Issue 3, 2011, Pages 871-879

  Pousa, Inés D ^a,b   Algaba, Alicia ^c   Linares, Pablo M ^a,b   Sanz Cameno, Paloma ^a,b   Maté, José ^a,b   Moreno Otero, Ricardo ^a,b   Bermejo, Fernando ^c   Gisbert, Javier P ^a,b,d  

^a HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL UNIVERSITARIO DE FUENLABRADA   (Spain)

^d NONE   (Spain)

Author keywords

Angiogenesis; Angiogenic factors; Ulcerative colitis; Vascular endothelial growth factor

Indexed keywords

AMINOSALICYLIC ACID; ANGIOGENIC FACTOR; ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; CORTICOSTEROID; PLACENTAL GROWTH FACTOR; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1;

ADULT; ANTIANGIOGENIC ACTIVITY; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE EXACERBATION; DISEASE SEVERITY; DOWN REGULATION; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FOLLOW UP; HUMAN; MALE; NEOVASCULARIZATION (PATHOLOGY); PREDICTION; PRIORITY JOURNAL; PROCTITIS; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; REMISSION; ULCERATIVE COLITIS;

ADRENAL CORTEX HORMONES; ADULT; ANGIOGENESIS INDUCING AGENTS; COLITIS, ULCERATIVE; FEMALE; HUMANS; MALE; MIDDLE AGED; PREGNANCY PROTEINS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79952442544     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-010-1327-x     Document Type: Article

References (45)

1. P Carmeliet 2003 Angiogenesis in health and disease Nat Med 9 653 660 1:CAS:528:DC%2BD3sXktFOntbY%3D 10.1038/nm0603-653 12778163 (Pubitemid 36749213)
2. P Carmeliet 2005 Angiogenesis in life, disease and medicine Nature 438 932 936 1:CAS:528:DC%2BD2MXhtlSksrjF 10.1038/nature04478 16355210 (Pubitemid 43093958)
3. J Folkman 1995 Angiogenesis in cancer, vascular, rheumatoid and other disease Nat Med 1 27 31 1:CAS:528:DyaK2MXjs1KnsLk%3D 10.1038/nm0195-27 7584949
4. L Deban C Correale S Vetrano, et al. 2008 Multiple pathogenic roles of microvasculature in inflammatory bowel disease: a jack of all trades Am J Pathol 172 1457 1466 1:CAS:528:DC%2BD1cXnslGqur4%3D 10.2353/ajpath.2008.070593 18458096 (Pubitemid 351793339)
5. ID Pousa JP Gisbert J Mate 2006 Vascular development in inflammatory bowel disease Gastroenterol Hepatol 29 414 421 10.1157/13091466 16938258 (Pubitemid 44386357)
6. ID Pousa J Mate JP Gisbert 2008 Angiogenesis in inflammatory bowel disease Eur J Clin Invest 38 73 81 1:CAS:528:DC%2BD1cXjsVeqs7Y%3D 10.1111/j.1365-2362.2007.01914.x 18226040 (Pubitemid 351143416)
7. J Medina L Garcia-Buey R Moreno-Otero 2003 Review article: immunopathogenetic and therapeutic aspects of autoimmune hepatitis Aliment Pharmacol Ther 17 1 16 1:STN:280:DC%2BD38jjtVSlsw%3D%3D 10.1046/j.1365-2036. 2003.01389.x 12492728
8. J Medina P Sanz-Cameno L Garcia-Buey, et al. 2005 Evidence of angiogenesis in primary biliary cirrhosis: an immunohistochemical descriptive study J Hepatol 42 124 131 1:CAS:528:DC%2BD2MXksVOg 10.1016/j.jhep.2004.09.024 15629517 (Pubitemid 40038910)
9. X Salcedo J Medina P Sanz-Cameno, et al. 2005 Review article: angiogenesis soluble factors as liver disease markers Aliment Pharmacol Ther 22 23 30 1:CAS:528:DC%2BD2MXnt1ymsr8%3D 10.1111/j.1365-2036.2005.02532.x 15963076 (Pubitemid 40943871)
10. X Salcedo J Medina P Sanz-Cameno, et al. 2005 The potential of angiogenesis soluble markers in chronic hepatitis C Hepatology 42 696 701 1:CAS:528:DC%2BD2MXhtVemt73O 10.1002/hep.20828 16104024 (Pubitemid 41233664)
11. C Medina MW Radomski 2006 Role of matrix metalloproteinases in intestinal inflammation J Pharmacol Exp Ther 318 933 938 1:CAS:528:DC%2BD28XovFygs7k%3D 10.1124/jpet.106.103465 16644899 (Pubitemid 44268297)
12. BA Imhof M Aurrand-Lions 2006 Angiogenesis and inflammation face off Nat Med 12 171 172 1:CAS:528:DC%2BD28XhtFWqtLw%3D 10.1038/nm0206-171 16462798 (Pubitemid 43214741)
13. DM Noonan A De Lerma Barbaro N Vannini, et al. 2008 Inflammation, inflammatory cells and angiogenesis: decisions and indecisions Cancer Metastasis Rev 27 31 40 10.1007/s10555-007-9108-5 18087678
14. R Benelli G Lorusso A Albini DM Noonan 2006 Cytokines and chemokines as regulators of angiogenesis in health and disease Curr Pharm Des 12 3101 3115 1:CAS:528:DC%2BD28Xotlalt7o%3D 10.2174/138161206777947461 16918437 (Pubitemid 44227572)
15. C Nathan 2002 Points of control in inflammation Nature 420 846 852 1:CAS:528:DC%2BD38XpsFygtLY%3D 10.1038/nature01320 12490957 (Pubitemid 36019637)
16. DG Binion P Rafiee 2009 Is inflammatory bowel disease a vascular disease? Targeting angiogenesis improves chronic inflammation in inflammatory bowel disease Gastroenterology 136 400 403 10.1053/j.gastro.2008.12.029 19111728
17. N Ferrara HP Gerber J LeCouter 2003 The biology of VEGF and its receptors Nat Med 9 669 676 1:CAS:528:DC%2BD3sXktFOnur4%3D 10.1038/nm0603-669 12778165 (Pubitemid 36749215)
18. M Autiero J Waltenberger D Communi, et al. 2003 Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1 Nat Med 9 936 943 1:CAS:528:DC%2BD3sXkvFOjsrc%3D 10.1038/nm884 12796773 (Pubitemid 36889938)
19. P Carmeliet L Moons A Luttun, et al. 2001 Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions Nat Med 7 575 583 1:CAS:528:DC%2BD3MXjsVakurc%3D 10.1038/87904 11329059 (Pubitemid 32448325)
20. AW Griffioen G Molema 2000 Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation Pharmacol Rev 52 237 268 1:CAS:528:DC%2BD3cXks1SksLw%3D 10835101 (Pubitemid 30368433)
21. ZL Zhang ZS Liu Q Sun 2006 Expression of angiopoietins, Tie2 and vascular endothelial growth factor in angiogenesis and progression of hepatocellular carcinoma World J Gastroenterol 12 4241 4245 1:CAS:528:DC%2BD28XhtVyis7rE 16830384 (Pubitemid 44376912)
22. JH Chidlow Jr.W Langston JJ Greer, et al. 2006 Differential angiogenic regulation of experimental colitis Am J Pathol 169 2014 2030 1:CAS:528:DC%2BD2sXhvV2htQ%3D%3D 10.2353/ajpath.2006.051021 17148665 (Pubitemid 351181962)
23. S Danese M Sans DM Spencer, et al. 2007 Angiogenesis blockade as a new therapeutic approach to experimental colitis Gut 56 855 862 1:CAS:528: DC%2BD2sXoslKisbo%3D 10.1136/gut.2006.114314 17170016 (Pubitemid 46854204)
24. IE Koutroubakis G Tsiolakidou K Karmiris EA Kouroumalis 2006 Role of angiogenesis in inflammatory bowel disease Inflamm Bowel Dis 12 515 523 10.1097/00054725-200606000-00012 16775497
25. S Kanazawa T Tsunoda E Onuma, et al. 2001 VEGF, basic-FGF, and TGF-beta in Crohn's disease and ulcerative colitis: a novel mechanism of chronic intestinal inflammation Am J Gastroenterol 96 822 828 1:CAS:528: DC%2BD3MXivFCnt7g%3D 11280558 (Pubitemid 32240738)
26. A Kapsoritakis A Sfiridaki E Maltezos, et al. 2003 Vascular endothelial growth factor in inflammatory bowel disease Int J Colorectal Dis 18 418 422 10.1007/s00384-003-0495-y 12761641 (Pubitemid 37062733)
27. GR Pinheiro CA Andrade CR Gayer, et al. 2001 Serum vascular endothelial growth factor in late rheumatoid arthritis Clin Exp Rheumatol 19 721 723 1:STN:280:DC%2BD38%2Fmslejtw%3D%3D 11791646 (Pubitemid 34026838)
28. J Strunk E Bundke U Lange 2006 Anti-TNF-alpha antibody Infliximab and glucocorticoids reduce serum vascular endothelial growth factor levels in patients with rheumatoid arthritis: a pilot study Rheumatol Int 26 252 256 1:CAS:528:DC%2BD2MXhtlekurvN 10.1007/s00296-005-0619-5 15999273 (Pubitemid 41830984)
29. SC Truelove LJ Witts 1955 Cortisone in ulcerative colitis; final report on a therapeutic trial Br Med J 2 1041 1048 1:STN:280:DyaG28%2Fht1Gksg%3D%3D 10.1136/bmj.2.4947.1041 13260656
30. de Dombal FT. Measuring and quantifying the status of patients with inflammatory bowel disease. In: de Dombal FT, Myren J, Bouchier IAD, Watkinson G, eds. Inflammatory Bowel Disease. Some International and Data Reflections. Oxford: Oxford University Press; 1986:267-285.
31. ID Pousa J Mate X Salcedo-Mora, et al. 2008 Role of vascular endothelial growth factor and angiopoietin systems in serum of Crohn's disease patients Inflamm Bowel Dis 14 61 67 10.1002/ibd.20269 17879276 (Pubitemid 351196870)
32. S Danese M Sans C de la Motte, et al. 2006 Angiogenesis as a novel component of inflammatory bowel disease pathogenesis Gastroenterology 130 2060 2073 1:CAS:528:DC%2BD28XntVWitrk%3D 10.1053/j.gastro.2006.03.054 16762629 (Pubitemid 43816964)
33. F Bach FJ Uddin D Burke 2007 Angiopoietins in malignancy Eur J Surg Oncol 33 7 15 1:STN:280:DC%2BD2s%2FltF2jsA%3D%3D 16962282 (Pubitemid 46156618)
34. T Griga A Tromm J Spranger B May 1998 Increased serum levels of vascular endothelial growth factor in patients with inflammatory bowel disease Scand J Gastroenterol 33 504 508 1:STN:280:DyaK1czhtFehtg%3D%3D 10.1080/ 00365529850172070 9648990 (Pubitemid 28277250)
35. Scaldaferri F, Vetrano S, Sans M, et al. VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis. Gastroenterology. 2009;136:585-595, e5.
36. F Magro F Araujo P Pereira, et al. 2004 Soluble selectins, sICAM, sVCAM, and angiogenic proteins in different activity groups of patients with inflammatory bowel disease Dig Dis Sci 49 1265 1274 1:CAS:528: DC%2BD2cXms1Cgt78%3D 10.1023/B:DDAS.0000037822.55717.31 15387356 (Pubitemid 39178099)
37. S Konno M Iizuka M Yukawa, et al. 2004 Altered expression of angiogenic factors in the VEGF-Ets-1 cascades in inflammatory bowel disease J Gastroenterol 39 931 939 1:CAS:528:DC%2BD2cXpt1ehsro%3D 10.1007/s00535-004-1423-9 15549445 (Pubitemid 39490169)
38. IE Koutroubakis C Xidakis K Karmiris, et al. 2006 Potential role of soluble angiopoietin-2 and Tie-2 in patients with inflammatory bowel disease Eur J Clin Invest 36 127 132 1:STN:280:DC%2BD28%2FltVGlsA%3D%3D 10.1111/j.1365-2362.2006.01602.x 16436095
39. WS Shim IA Ho PE Wong 2007 Angiopoietin: a TIE(d) balance in tumor angiogenesis Mol Cancer Res 5 655 665 1:CAS:528:DC%2BD2sXnvVCht7Y%3D 10.1158/1541-7786.MCR-07-0072 17634421 (Pubitemid 47105484)
40. U Fiedler Y Reiss M Scharpfenecker, et al. 2006 Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation Nat Med 12 235 239 1:CAS:528:DC%2BD28XhtFWqu74%3D 10.1038/nm1351 16462802 (Pubitemid 43214752)
41. D Pfaff U Fiedler HG Augustin 2006 Emerging roles of the angiopoietin-Tie and the ephrin-Eph systems as regulators of cell trafficking J Leukoc Biol 80 719 726 1:CAS:528:DC%2BD28XhtV2hsLzI 10.1189/jlb.1105652 16864601 (Pubitemid 44835887)
42. N Hanabata Y Sasaki M Tanaka, et al. 2005 Vascular endothelial growth factor expression and microvessel parameters of colonic mucosa correlate with sensitivity to steroid in patients with ulcerative colitis Scand J Gastroenterol 40 188 193 1:CAS:528:DC%2BD2MXnt1eksw%3D%3D 10.1080/00365520410010580 15764150 (Pubitemid 40188999)
43. N Bandi UB Kompella 2001 Budesonide reduces vascular endothelial growth factor secretion and expression in airway (Calu-1) and alveolar (A549) epithelial cells Eur J Pharmacol 425 109 116 1:CAS:528:DC%2BD3MXlvFWrsb0%3D 10.1016/S0014-2999(01)01192-X 11502275 (Pubitemid 32739155)
44. UB Kompella N Bandi SP Ayalasomayajula 2003 Subconjunctival nano- and microparticles sustain retinal delivery of budesonide, a corticosteroid capable of inhibiting VEGF expression Invest Ophthalmol Vis Sci 44 1192 1201 10.1167/iovs.02-0791 12601049 (Pubitemid 36297840)
45. HA Kader VT Tchernev E Satyaraj, et al. 2005 Protein microarray analysis of disease activity in pediatric inflammatory bowel disease demonstrates elevated serum PLGF, IL-7, TGF-beta1, and IL-12p40 levels in Crohn's disease and ulcerative colitis patients in remission versus active disease Am J Gastroenterol 100 414 423 1:CAS:528:DC%2BD2MXisVeitLY%3D 10.1111/j.1572-0241. 2005.40819.x 15667502 (Pubitemid 40314529)