Rheology, granule growth and granule strength: Application to the wet granulation of lactose-MCC mixtures

Powder Technology

Volumn 208, Issue 2, 2011, Pages 441-453

  Chitu, T M ^a   Oulahna, D ^a   Hemati, M ^b  

^a ECOLE DES MINES D ALBI CARMAUX   (France)

^b LABORATOIRE DE GÉNIE CHIMIQUE   (France)

Author keywords

Granule strength; Lactose; Microcrystalline cellulose; Rheology; Wet granulation

Indexed keywords

BINARY MIXTURES; CELLULOSE; CRYSTALLINE MATERIALS; ELASTICITY; GROWTH KINETICS; MIXERS (MACHINERY); RHEOLOGY; SUGARS;

GRANULATION PROCESS; GRANULE SIZE DISTRIBUTION; GRANULE STRENGTHS; LACTOSE; MICRO-CRYSTALLINE CELLULOSE; MOISTURE SORPTION ISOTHERMS; NUCLEATION AND GROWTH; WET GRANULATION;

GRANULATION;

ALPHA LACTOSE; MICROCRYSTALLINE CELLULOSE;

ARTICLE; CHEMICAL COMPOSITION; CHEMICAL PROCEDURES; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRY MASS; EQUIPMENT DESIGN; FLOW KINETICS; GROWTH RATE; IMPELLER; ISOTHERM; MOLECULAR WEIGHT; PARTICLE SIZE; PROCESS OPTIMIZATION; SCALE UP; SHEAR STRENGTH; TORQUE; WET GRANULATION;

EID: 79952441778     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2010.08.041     Document Type: Article

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