Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model

Journal of Clinical Biochemistry and Nutrition

Volumn 48, Issue 2, 2011, Pages 161-166

  Inoue, Motoki ^a   Tazuma, Susumu ^b   Kanno, Keishi ^b   Hyogo, Hideyuki ^a   Igarashi, Kazuhiko ^c   Chayama, Kazuaki ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Heme oxygenase 1; Nonalcoholic fatty liver disease; Oxidative stress; Peroxisome proliferator activated receptor ; Steatohepatitis

Indexed keywords

ALANINE AMINOTRANSFERASE; CHOLINE; HEME OXYGENASE 1; MALONALDEHYDE; MESSENGER RNA; METHIONINE; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TRIACYLGLYCEROL;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACH1 GENE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; FIBROGENESIS; GENE EXPRESSION; LIPID METABOLISM; LIVER INJURY; LIVER LEVEL; LIVER PROTECTION; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; REPRESSOR GENE; UPREGULATION;

MUS;

EID: 79952425249     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.09-122GFR     Document Type: Article

References (34)

1. Vuppalanchi R, Chalasani N. Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management. Hepatology 2009; 49: 306-317.
2. Farrell GC, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006; 43: S99-S112.
3. Day CP, James OF. Steatohepatitis: a tale of two "hits"? Gastroenterology 1998; 114: 842-845.
4. Nan YM, Wu WJ, Fu N, and et al. Antioxidants vitamin E and 1-aminobenzotriazole prevent experimental non-alcoholic steatohepatitis in mice. Scand J Gastroenterol 2009; 15: 1-11.
5. Ramirez-Tortosa MC, Ramirez-Tortosa CL, Mesa MD, Granados S, Gil A, Quiles JL. Curcumin ameliorates rabbits's steatohepatitis via respiratory chain, oxidative stress, and TNF-alpha. Free Radic Biol Med 2009; 47: 924-931.
6. Baumgardner JN, Shankar K, Hennings L, Albano E, Badger TM, Ronis MJ. N-acetylcysteine attenuates progression of liver pathology in a rat model of nonalcoholic steatohepatitis. J Nutr 2008; 138: 1872-1879.
7. Hirose A, Ono M, Saibara T, and et al. Angiotensin II type 1 receptor blocker inhibits fibrosis in rat nonalcoholic steatohepatitis. Hepatology 2007; 45: 1375-1381. (Pubitemid 46918321)
8. Hasegawa T, Yoneda M, Nakamura K, Makino I, Terano A. Plasma transforming growth factor-beta1 level and efficacy of alpha-tocopherol in patients with non-alcoholic steatohepatitis: a pilot study. Aliment Pharmacol Ther 2001; 15: 1667-1672. (Pubitemid 32912411)
9. Dufour JF, Oneta CM, Gonvers JJ, and et al. Swiss Association for the Study of the Liver: Randomized placebo-controlled trial of ursodeoxycholic acid with vitamin e in nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol 2006; 4: 1537-1543. (Pubitemid 44880031)
10. Harrison SA, Torgerson S, Hayashi P, Ward J, Schenker S. Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis. Am J Gastroenterol 2003; 98: 2485-2490. (Pubitemid 37448761)
11. Nakamoto K, Takayama F, Mankura M, and et al. Beneficial effects of fermented green tea extract in a rat model of non-alcoholic steatohepatitis. J Clin Biochem Nutr 2009; 44: 239-246.
12. Takahashi T, Shimizu H, Morimatsu H, and et al. Heme oxygenase-1 is an essential cytoprotective component in oxidative tissue injury induced by hemorrhagic shock. J Clin Biochem Nutr 2009; 44: 28-40.
13. Hayashi S, Omata Y, Sakamoto H, and et al. Characterization of rat heme oxygenase-3 gene. Implication of processed pseudogenes derived from heme oxygenase-2 gene. Gene 2004; 336: 241-250.
14. Malaguarnera L, Madeddu R, Palio E, Arena N, Malaguarnera M. Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients. J Hepatol 2005; 42: 585-591. (Pubitemid 40342940)
15. Liu LG, Yan H, Zhang W, and et al. Induction of heme oxygenase-1 in human hepatocytes to protect them from ethanol-induced cytotoxicity. Biomed Environ Sci 2004; 17: 315-326. (Pubitemid 39486798)
16. Yao P, Li K, Song F, and et al. Heme oxygenase-1 upregulated by Ginkgo biloba extract: potential protection against ethanol-induced oxidative liver damage. Food Chem Toxicol 2007; 45: 1333-1342. (Pubitemid 47033946)
17. McNally SJ, Harrison EM, Ross JA, Garden OJ, Wigmore SJ. Curcumin induces heme oxygenase-1 in hepatocytes and is protective in simulated cold preservation and warm reperfusion injury. Transplantation 2006; 81: 623-626.
18. Sun J, Hoshino H, Takaku K, and et al. Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene. EMBO J 2002; 21: 5216-5224.
19. Iida A, Inagaki K, Miyazaki A, Yonemori F, Ito E, Igarashi K. Bach1 deficiency ameliorates hepatic injury in a mouse model. Tohoku J Exp Med 2009; 217: 223-229.
20. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37: 911-917.
21. Yano Y, Ozono R, Oishi Y, and et al. Genetic ablation of the transcription repressor Bach1 leads to myocardial protection against ischemia/reperfusion in mice. Genes Cells 2006; 11: 791-803. (Pubitemid 43923350)
22. Yoshida T, Kikuchi G. Reaction of the microsomal heme oxygenase with cobaltic protoporphyrin IX, and extremely poor substrate. J Biol Chem 1978; 253: 8479-8482. (Pubitemid 9082553)
23. Nabeshima Y, Tazuma S, Kanno K, Hyogo H, Chayama K. Deletion of angiotensin II type I receptor reduces hepatic steatosis. J Hepatol 2009; 50: 1226-1235.
24. Hintze KJ, Katoh Y, Igarashi K, Theil EC. Bach1 repression of ferritin and thioredoxin reductase1 is heme-sensitive in cells and in vitro and coordinates expression with heme oxygenase1, beta-globin, and NADP(H) quinone (oxido) reductase1. J Biol Chem 2007; 282: 34365-34371. (Pubitemid 350159431)
25. Farombi EO, Surh YJ. Heme oxygenase-1 as a potential therapeutic target for hepatoprotection. J Biochem Mol Biol 2006; 39: 479-491. (Pubitemid 44714527)
26. Wang F, Duan ZJ, Sun YJ. Influence of heme oxygenase-1 expression on immune liver fibrosis induced by cobalt protoporphyrin in rats. World J Gastroenterol 2009; 15: 3009-3014.
27. Schmidt R, Tritschler E, Hoetzel A, and et al. Heme oxygenase-1 induction by the clinically used anesthetic isoflurane protects rat livers from ischemia/reperfusion injury. Ann Surg 2007; 245: 931-942. (Pubitemid 46809295)
28. de Lima VM, de Oliveira CP, Sawada LY, and et al. Yo jyo hen shi ko, a novel Chinese herbal, prevents nonalcoholic steatohepatitis in ob/ob mice fed a high fat or methionine-choline-deficient diet. Liver Int 2007; 27: 227-234. (Pubitemid 46680727)
29. Stefano JT, de Oliveira CP, Corrêa-Giannella ML, and et al. Nonalcoholic steatohepatitis (NASH) in ob/ob mice treated with yo jyo hen shi ko (YHK): effects on peroxisome proliferator-activated receptors (PPARs) and microsomal triglyceride transfer protein (MTP). Dig Dis Sci 2007; 52: 3448-3454.
30. Mantena SK, Vaughn DP, Andringa KK, and et al. High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo. Biochem J 2009; 417: 183-193.
31. Hensley K, Kotake Y, Sang H, and et al. Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria. Carcinogenesis 2000; 21: 983-989.
32. Li L, Grenard P, Nhieu JT, and et al. Heme oxygenase-1 is an antifibrogenic protein in human hepatic myofibroblasts. Gastroenterology 2003; 125: 460-469.
33. Collins S, Martin TL, Surwit RS, Robidoux J. Genetic vulnerability to diet-induced obesity in the C57BL/6J mouse: physiological and molecular characteristics. Physiol Behav 2004; 81: 243-248. (Pubitemid 38670090)
34. Takayama F, Egashira T, Kawasaki H, and et al. A novel animal model of nonalcoholic steatohepatitis (NASH): hypoxemia enhances the development of NASH. J Clin Biochem Nutr 2009; 45: 335-340.