Renal anemia: A nephrologist's view

Hippokratia

Volumn 15, Issue SUPPL. 1, 2011, Pages 39-43

  Tsagalis, G ^a  

^a ALEXANDRA HOSPITAL   (Greece)

Author keywords

Anemiaprevalence; Chronic kidney disease; Erythropoietin receptors; Ferritin; Transferrin saturation

Indexed keywords

CYANOCOBALAMIN; ERYTHROPOIETIN; FERRITIN; FOLIC ACID; IRON; TRANSFERRIN; UREMIC TOXIN;

ADULT; ANEMIA; BLOOD CELL COUNT; BONE MARROW; CHRONIC KIDNEY DISEASE; DIABETES MELLITUS; ERYTHROCYTE LIFESPAN; ERYTHROID PRECURSOR CELL; ERYTHROPOIESIS; FERRITIN BLOOD LEVEL; FETUS; GLOMERULUS FILTRATION RATE; HORMONE SYNTHESIS; HUMAN; HYPERSPLENISM; HYPOTHYROIDISM; HYPOXIA; INFECTION; INFLAMMATION; KIDNEY CELL; KIDNEY FAILURE; LIVER CELL; NEPHROLOGIST; PERITUBULAR CELL; PREVALENCE; RETICULOCYTE; REVIEW; VITAMIN BLOOD LEVEL;

EID: 79952424010     PISSN: 11084189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (28)

1. Astor BC, Muntner P, Levin A, Eustace JA, Coresh J. Association of kidney function with anemia: the Third National Health and Nutrition Examination Survey (1988-1994). Arch Intern Med 2002; 162: 1401-1408.
2. Hsu CY, McCulloch CE, Curhan GC. Epidemiology of anemia associated with chronic renal insufficiency among adults in the United States: results from the Third National Health and Nutrition Examination Survey. J Am Soc Nephrol 2002; 13: 504-510.
3. El-Achkar TM, Ohmit SE, McCullough PA, et al. Higher prevalence of anemia with diabetes mellitus in moderate kidney insufficiency: The Kidney Early Evaluation Program. Kidney Int 2005; 67: 1483-1488.
4. US Renal Data System: USRDS 2004 Annual Data Report. Bethesda, MD, The National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, 2004.
5. Levin A, Thompson CR, Ethier J, et al: Left Ventricular mass index increase in early renal disease: impact of decline in haemoglobin. Am J Kidney Dis 1999; 34: 125-134.
6. Lappin TR, Maxwell AP, Johnston PG. EPO's alter ego: erythropoietin has multiple actions. Stem Cells 2002; 20: 485-492.
7. Maxwell AP. Novel erythropoiesis-stimulating protein in the management of the anemia of chronic renal failure. Kidney Int 2002; 62: 720-729.
8. Erslev AJ, Gabuzda TG. Pathophysiology of Blood, third edition. Philadelphia: WB Saunders, 1985: 28-134.
9. Lenga I, Donnelly S. Angiotensin II stimulates erythropoietin production in humans [abstract]. J Am Soc Nephrol 2000; 11: 45A. Abstract A0246.
10. Chappey O, Wautier-Pepin MP, Wautier JL. Adhesion of erythrocytes to endothelium in pathological situations: a review article. Nouv Rev Fr Hematol 1994; 36: 281-288.
11. Perros P, Singh RK, Ludlam CA, Frier BM. Prevalence of pernicious anaemia in patients with type 1 diabetes mellitus and autoimmune thyroid disease. Diabet Med 2000; 17: 749-751.
12. Silverberg D, Wexler D, Iauna A. The importance of anemia and its correction in the management of severe congestive heart failure. Eur J Heart Fail 2002; 4: 681-686.
13. Muñoz Gómez M, Campos Garríguez A, García Erce JA, Ramírez Ramírez G. [Fisiopathology of iron metabolism: diagnostic and therapeutic implications]. Nefrologia. 2005; 25: 9-19
14. Andrews NC. Disorders of iron metabolism. N Engl J Med 1999; 341: 1986-1995.
15. Siah CW, Ombiga J, Adams LA, Trinder D, Olynyk JK. Normal iron metabolism and the pathophysiology of iron overload disorders. Clin Biochem Rev 2006; 27: 5-16.
16. Nemeth E, Ganz T. Hepcidin and iron-loading anemias. Haematologica 2006; 91: 727-732.
17. Ponka P. Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells. Blood 1997; 89: 1-25.
18. Zak O, Trinder D, Aisen P. Primary receptor-recognition site of human transferrin is in the C-terminal lobe. J Biol Chem 1994; 269: 7110-7114.
19. Van Renswoude J, Bridges KR, Harford JB, Klausner RD. Receptor- mediated endocytosis and the uptake of iron in K562 cells: Identification of a non-lysosomal acidic compartment. Proc Natl Acad Sci USA 1982; 79: 6186-6190.
20. Klausner RD, van Renswoude J, Ashwell G, Kempf C, Schechter AM, Dean A, Bridges KR. Receptor-mediated endocytosis of transferrin in K562 cells. J Biol Chem 1983; 258: 4715-4724.
21. Dautry-Varsat A, Ciechanover A, Lodish HF. pH and the recycling of transferrin during receptor-mediated endocytosis. PNAS 1983; 80: 2258-2262.
22. Harford JB, Rouault TA, Huebers HA, Klausner RD. Molecular mechanisms of iron metabolism. In The Molecular Basis of Blood Diseases, G. Stamatoyannopoulos, A. W. Nienhuis, P. W. Majerus and H. Varmus, eds. (Philadelphia: W.B. Saunders Co.), 1994; pp. 351-378.
23. Crichton RR, Danielsson BG, Geisser P. Iron metabolism: biologic and molecular aspects. In: Crichton RR, Danielsson BG, Geisser P, editors. Iron therapy with special emphasis on intravenous administration. 4th ed. Bremen: UNI-Med Verlag AG; 2008; pp. 14-24.
24. Rambod M, Kovesdy CP, Kalantar-Zadeh K. Combined high serum ferritin and low iron saturation in hemodialysis patients: the role of inflammation. Clin J Am Soc Nephrol 2008; 6: 1691-1701.
25. Coyne DW, Kapoian T, Suki W, Singh AK, Moran JE, Dahl NV, Rizkala AR. Ferric Gluconate Is Highly Efficacious in Anemic Hemodialysis Patients with High Serum Ferritin and Low Transferrin Saturation: Results of the Dialysis Patients' Response to IV Iron with Elevated Ferritin (DRIVE) Study. J Am Soc Nephrol 2007; 3: 975-984.
26. Singh AK, Coyne DW, Shapiro W, Rizkala AR. Predictors of the response to treatment in anemic hemodialysis patients with high serum ferritin and low transferrin saturation. Kidney Int 2007; 11: 1163-1171.
27. Fishbane S, Kowalski EA, Imbriano LJ, Maesaka JK. The evaluation of iron status in hemodialysis patients. J Am Soc Nephrol 1996; 7: 265-407.
28. Kalantar-Zadeh K, Hoffken B, Wünsch H, Fink H, Kleiner M, Luft FC. Diagnosis of iron deficiency anemia in renal failure patients during the post-erythropoietin era. Am J Kidney Dis 1995; 26: 292-299.