Case 7-2011: A 52-year-old man with upper respiratory symptoms and low oxygen saturation levels

New England Journal of Medicine

Volumn 364, Issue 10, 2011, Pages 957-966

  Pallais, J Carl ^a,b   Mackool, Bonnie T ^a,b   Pitman, Martha Bishop ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DAPSONE; FLUTICASONE; FRUCTOSAMINE; HEMOGLOBIN A1C; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN; OXYGEN;

ADULT; ARTICLE; CASE REPORT; COUGHING; DERMATITIS HERPETIFORMIS; DIABETES MELLITUS; FATIGUE; FEVER; GLYCEMIC CONTROL; HEADACHE; HEMOLYSIS; HUMAN; HYPERBILIRUBINEMIA; HYPOXEMIA; MALE; MEASUREMENT ERROR; METHEMOGLOBINEMIA; NOSE CONGESTION; OXYGEN SATURATION; PNEUMONIA; PRIORITY JOURNAL; PULSE OXIMETRY; RESPIRATORY DISTRESS; RESPIRATORY TRACT DISEASE; RETICULOCYTOSIS; SINUS CONGESTION; SORE THROAT; UPPER RESPIRATORY SYMPTOM; BLOOD; CELIAC DISEASE; CHEMICALLY INDUCED DISORDER; CLINICAL OBSERVATION; CLINICAL STUDY; DIAGNOSIS; DIFFERENTIAL DIAGNOSIS; DUODENUM; INSULIN DEPENDENT DIABETES MELLITUS; MIDDLE AGED; OXIMETRY; PATHOLOGY; SKIN;

CELIAC DISEASE; COUGH; DAPSONE; DERMATITIS HERPETIFORMIS; DIABETES MELLITUS, TYPE 1; DIAGNOSIS, DIFFERENTIAL; DUODENUM; HEMOGLOBIN A, GLYCOSYLATED; HEMOLYSIS; HUMANS; MALE; METHEMOGLOBINEMIA; MIDDLE AGED; OXIMETRY; OXYGEN; SKIN;

EID: 79952397807     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcpc1013923     Document Type: Article

References (57)

1. Tremper KK, Barker SJ. Pulse oximetry. Anesthesiology 1989;70:98-108. (Pubitemid 19042771)
2. Case Records of the Massachusetts General Hospital (Case 23-2004). N Engl J Med 2004;351:380-7.
3. Pierson DJ. Pathophysiology and clinical effects of chronic hypoxia. Respir Care 2000;45:39-51.
4. Haymond S, Cariappa R, Eby CS, Scott MG. Laboratory assessment of oxygenation in methemoglobinemia. Clin Chem 2005;51:434-44. (Pubitemid 40175815)
5. Zur B, Hornung A, Breuer J, et al. A novel hemoglobin, Bonn, causes falsely decreased oxygen saturation measurements in pulse oximetry. Clin Chem 2008;54:594-6. (Pubitemid 351348167)
6. Ash-Bernal R, Wise R, Wright SM. Acquired methemoglobinemia: a retrospective series of 138 cases at 2 teaching hospitals. Medicine (Baltimore) 2004;83:265-73. (Pubitemid 39258412)
7. Jollow DJ, Bradshaw TP, McMillan DC. Dapsone-induced hemolytic anemia. Drug Metab Rev 1995;27:107-24.
8. Barker SJ, Tremper KK, Hyatt J. Effects of methemoglobinemia on pulse oximetry and mixed venous oximetry. Anesthesiology 1989;70:112-7. (Pubitemid 19042773)
9. Wright RO, Lewander WJ, Woolf AD. Methemoglobinemia: etiology, pharmacology, and clinical management. Ann Emerg Med 1999;34:646-56. (Pubitemid 29510918)
10. Guay J. Methemoglobinemia related to local anesthetics: a summary of 242 episodes. Anesth Analg 2009;108:837-45.
11. Armbruster DA. Fructosamine: structure, analysis, and clinical usefulness. Clin Chem 1987;33:2153-63.
12. Bunn HF, Haney DN, Kamin S, Gabbay KH, Gallop PM. The biosynthesis of human hemoglobin A1c: slow glycosylation of hemoglobin in vivo. J Clin Invest 1976;57:1652-9.
13. Staley MJ. Fructosamine and protein concentrations in serum. Clin Chem 1987;33:2326-7.
14. Nathan DM, Kuenen J, Borg R, Zheng H, Schoenfeld D, Heine RJ. Translating the A1C assay into estimated average glucose values. Diabetes Care 2008;31:1473-8. [Erratum, Diabetes Care 2009;32:207.]
15. International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes. Diabetes Care 2009;32:1327-34.
16. Standards of medical care in diabetes - 2010. Diabetes Care 2010;33:Suppl 1:S11-S61.
17. Mendlovic DB, Whitehouse FW, Foreback CC. The why and wherefore of fructosamine. Henry Ford Hosp Med J 1992;40:149-51.
18. Tahara Y, Shima K. Kinetics of HbA1c, glycated albumin, and fructosamine and analysis of their weight functions against preceding plasma glucose level. Diabetes Care 1995;18:440-7.
19. Bloomgarden ZT. A1C: recommendations, debates, and questions. Diabetes Care 2009;32(12):e141-e147.
20. Factors that interfere with GHB (HbA1c) test results. NGSP 2010. (http:// www.ngsp.org/factors.asp.)
21. Saudek CD, Derr RL, Kalyani RR. Assessing glycemia in diabetes using self-monitoring blood glucose and hemoglobin A1c. JAMA 2006;295:1688-97.
22. Saudek CD, Herman WH, Sacks DB, Bergenstal RM, Edelman D, Davidson MB. A new look at screening and diagnosing diabetes mellitus. J Clin Endocrinol Metab 2008;93:2447-53. (Pubitemid 352008502)
23. Cohen RM, Smith EP. Frequency of HbA1c discordance in estimating blood glucose control. Curr Opin Clin Nutr Metab Care 2008;11:512-7.
24. Albright ES, Ovalle F, Bell DS. Artificially low hemoglobin A1c caused by use of dapsone. Endocr Pract 2002;8:370-2.
25. Bertholon M, Mayer A, Francina A, Thivolet CH. Interference of dapsone in HbA1c monitoring of a type I diabetic patient with necrobiosis lipoidica. Diabetes Care 1994;17:1364. (Pubitemid 24324988)
26. Serratrice J, Granel B, Swiader L, et al. Interference of dapsone in HbA1c monitoring of a diabetic patient with polychondritis. Diabetes Metab 2002;28:508-9. (Pubitemid 36077155)
27. Tack CJ, Wetzels JF. Decreased HbA1c levels due to sulfonamide-induced hemolysis in two IDDM patients. Diabetes Care 1996;19:775-6.
28. Froud T, Faradji RN, Gorn L, et al. Dapsone-induced artifactual a1c reduction in islet transplant recipients. Transplantation 2007;83:824-5. (Pubitemid 46569204)
29. Duhring L. Dermatitis herpetiformis. JAMA 1884;3:225.
30. Fry L, Keir P, McMinn RM, Cowan JD, Hoffbrand AV. Small-intestinal structure and function and haematological changes in dermatitis herpetiformis. Lancet 1967;2:729-33.
31. Gawkrodger DJ, Blackwell JN, Gilmour HM, Rifkind EA, Heading RC, Barnetson RS. Dermatitis herpetiformis: diagnosis, diet and demography. Gut 1984;25:151-7.
32. Alonso-Llamazares J, Gibson LE, Rogers RS III. Clinical, pathologic, and immunopathologic features of dermatitis herpetiformis: review of the Mayo Clinic experience. Int J Dermatol 2007;46:910-9. (Pubitemid 47382275)
33. Caproni M, Antiga E, Melani L, Fabbri P. Guidelines for the diagnosis and treatment of dermatitis herpetiformis. J Eur Acad Dermatol Venereol 2009;23:633-8.
34. Fry L, Seah PP. Dermatitis herpetiformis: an evaluation of diagnostic criteria. Br J Dermatol 1974;90:137-46.
35. Fry L, Seah PP, McMinn RM, Hoffbrand AV. Lymphocytic infiltration of epithelium in diagnosis of gluten-sensitive enteropathy. BMJ 1972;3:371-4.
36. Galvez L, Falchuk ZM. Dermatitis herpetiformis: gastrointestinal association. Clin Dermatol 1991;9:325-33.
37. Fry L, McMinn RM, Cowan JD, Hoffbrand AV. Effect of gluten-free diet on dermatological, intestinal, and haematological manifestations of dermatitis herpetiformis. Lancet 1968;1:557-61.
38. Idem. Gluten-free diet and reintroduction of gluten in dermatitis herpetiformis. Arch Dermatol 1969;100:129-35.
39. Pink IJ, Creamer B. Response to a gluten-free diet of patients with the coeliac syndrome. Lancet 1967;1:300-4.
40. Hardman CM, Garioch JJ, Leonard JN, et al. Absence of toxicity of oats in patients with dermatitis herpetiformis. N Engl J Med 1997;337:1884-7. (Pubitemid 28053028)
41. Garioch JJ, Lewis HM, Sargent SA, Leonard JN, Fry L. 25 Years' experience of a gluten-free diet in the treatment of dermatitis herpetiformis. Br J Dermatol 1994;131:541-5. (Pubitemid 24315424)
42. Katz SI, Hall RP III, Lawley TJ, Strober W. Dermatitis herpetiformis: the skin and the gut. Ann Intern Med 1980;93:857-74. (Pubitemid 11197795)
43. Leonard JN, Fry L. Treatment and management of dermatitis herpetiformis. Clin Dermatol 1991;9:403-8.
44. Coleman MD. Dapsone: modes of action, toxicity and possible strategies for increasing patient tolerance. Br J Dermatol 1993;129:507-13. (Pubitemid 23336444)
45. Paniker U, Levine N. Dapsone and sulfapyridine. Dermatol Clin 2001;19:79-86. (Pubitemid 32038047)
46. Lewis HM, Renaula TL, Garioch JJ, et al. Protective effect of gluten-free diet against development of lymphoma in dermatitis herpetiformis. Br J Dermatol 1996;135:363-7. (Pubitemid 26297828)
47. Chorzelski TP, Jablonska S. IgA linear dermatosis of childhood (chronic bullous disease of childhood). Br J Dermatol 1979;101:535-42. (Pubitemid 10132178)
48. Dieterich W, Ehnis T, Bauer M, et al. Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med 1997;3:797-801. (Pubitemid 27298728)
49. Marietta EV, Camilleri MJ, Castro LA, Krause PK, Pittelkow MR, Murray JA. Transglutaminase autoantibodies in dermatitis herpetiformis and celiac sprue. J Invest Dermatol 2008;128:332-5.
50. Sárdy M, Kárpáti S, Merkl B, Paulsson M, Smyth N. Epidermal transglutaminase (TGase 3) is the autoantigen of dermatitis herpetiformis. J Exp Med 2002;195:747-57. (Pubitemid 34259719)
51. Egan CA, O'Loughlin S, Gormally S, Powell FC. Dermatitis herpetiformis: a review of fifty-four patients. Ir J Med Sci 1997;166:241-4. (Pubitemid 27500869)
52. Gawkrodger DJ, Vestey JP, O'Mahony S, Marks JM. Dermatitis herpetiformis and established coeliac disease. Br J Dermatol 1993;129:694-5. (Pubitemid 24003555)
53. Mäki M, Mustalahti K, Kokkonen J, et al. Prevalence of celiac disease among children in Finland. N Engl J Med 2003;348:2517-24. (Pubitemid 36706539)
54. Hunt KA, Zhernakova A, Turner G, et al. Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet 2008;40:395-402. (Pubitemid 351450876)
55. Cooper JD, Smyth DJ, Smiles AM, et al. Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. Nat Genet 2008;40:1399-401.
56. Todd JA, Walker NM, Cooper JD, et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 2007;39:857-64. (Pubitemid 47018195)
57. Smyth DJ, Plagnol V, Walker NM, et al. Shared and distinct genetic variants in type 1 diabetes and celiac disease. N Engl J Med 2008;359:2767-77.