-
1
-
-
0000586975
-
The preparation, purification, and amino acid sequence of a polypeptide renin substrate
-
Skeggs LT, Kahn JR, Lentz K, Shumway NP. The preparation, purification, and amino acid sequence of a polypeptide renin substrate. J Exp Med 1957;106: 439-453.
-
(1957)
J Exp Med
, vol.106
, pp. 439-453
-
-
Skeggs, L.T.1
Kahn, J.R.2
Lentz, K.3
Shumway, N.P.4
-
2
-
-
70249125414
-
Angiotensin II receptor blocker is a renoprotective remedy for metabolic syndrome
-
Sofue T, Kiyomoto H. Angiotensin II receptor blocker is a renoprotective remedy for metabolic syndrome. Hypertens Res 2009;32: 735-737.
-
(2009)
Hypertens Res
, vol.32
, pp. 735-737
-
-
Sofue, T.1
Kiyomoto, H.2
-
3
-
-
74849089254
-
Direct renin inhibition and the kidney
-
Hollenberg NK. Direct renin inhibition and the kidney. Nat Rev Nephrol 2010;6: 49-55.
-
(2010)
Nat Rev Nephrol
, vol.6
, pp. 49-55
-
-
Hollenberg, N.K.1
-
4
-
-
77957334373
-
Role of (pro)renin receptor in cardiovascular cells from the aspect of signaling
-
Hitom H, Liu G, Nishiyama A. Role of (pro)renin receptor in cardiovascular cells from the aspect of signaling. Front Biosci 2010;2: 1246-1249.
-
(2010)
Front Biosci
, vol.2
, pp. 1246-1249
-
-
Hitom, H.1
Liu, G.2
Nishiyama, A.3
-
5
-
-
33747060126
-
Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats
-
DOI 10.1038/sj.ki.5001627, PII 5001627
-
Kaneshiro Y, Ichihara A, Takemitsu T, Sakoda M, Suzuki F, Nakagawa T, Hayashi M, Inagami T. Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats. Kidney Int 2006;70: 641-646. (Pubitemid 44215337)
-
(2006)
Kidney International
, vol.70
, Issue.4
, pp. 641-646
-
-
Kaneshiro, Y.1
Ichihara, A.2
Takemitsu, T.3
Sakoda, M.4
Suzuki, F.5
Nakagawa, T.6
Hayashi, M.7
Inagami, T.8
-
6
-
-
71949102843
-
Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (Pro)renin receptor expression
-
Huang J, Siragy HM. Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (Pro)renin receptor expression. Endocrinology 2009;150: 5557-5565.
-
(2009)
Endocrinology
, vol.150
, pp. 5557-5565
-
-
Huang, J.1
Siragy, H.M.2
-
7
-
-
77649171183
-
(Pro) renin receptor contributes to diabetic nephropathy through enhancing renal inflammation
-
Matavelli LC, Huang J, Siragy HM. (Pro)renin receptor contributes to diabetic nephropathy through enhancing renal inflammation. Clin Exp Pharmacol Physiol 2009;37: 277-282.
-
(2009)
Clin Exp Pharmacol Physiol
, vol.37
, pp. 277-282
-
-
Matavelli, L.C.1
Huang, J.2
Siragy, H.M.3
-
9
-
-
0037591344
-
Human prorenin has "gate and handle" regions for its non-proteolytic activation
-
DOI 10.1074/jbc.M302579200
-
Suzuki F, Hayakawa M, Nakagawa T, Nasir UM, Ebihara A, Iwasawa A, Ishida Y, Nakamura Y, Murakami K. Human prorenin has 'gate and handle' regions for its non-proteolytic activation. J Biol Chem 2003;278: 22217-22222. (Pubitemid 36830267)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.25
, pp. 22217-22222
-
-
Suzuki, F.1
Hayakawa, M.2
Nakagawa, T.3
Nasir, U.M.4
Ebihara, A.5
Iwasawa, A.6
Ishida, Y.7
Nakamura, Y.8
Murakami, K.9
-
10
-
-
15144347939
-
Determinants of interindividual variation of renin and prorenin concentrations: Evidence for a sexual dimorphism of (pro)renin levels in humans
-
DOI 10.1097/00004872-199816060-00017
-
Danser AH, Derkx FH, Schalekamp MA, Hense HW, Riegger GA, Schunkert H. Determinants of interindividual variation of renin and prorenin concentrations: evidence for a sexual dimorphism of (pro)renin levels in humans. J Hypertens 1998;16: 853-862. (Pubitemid 28247969)
-
(1998)
Journal of Hypertension
, vol.16
, Issue.6
, pp. 853-862
-
-
Jan Danser, A.H.1
Derkx, F.H.M.2
Schalekamp, M.A.D.H.3
Hense, H.-W.4
Riegger, G.A.J.5
Schunkert, H.6
-
11
-
-
0020351976
-
Changes in active and inactive renin throughout normal pregnancy
-
Sealey JE, Wilson M, Morganti AA, Zervoudakis I, Laragh JH. Changes in active and inactive renin throughout normal pregnancy. Clin Exp Hypertens A 1982;4: 2373-2384. (Pubitemid 13190873)
-
(1982)
Clinical and Experimental Hypertension - Part A Theory and Practice
, vol.4
, Issue.11-12
, pp. 2373-2384
-
-
Sealey, J.E.1
Wilson, M.2
Morganti, A.A.3
-
12
-
-
0032787740
-
Increase in serum prorenin precedes onset of microalbuminuria in patients with insulin-dependent diabetes mellitus
-
DOI 10.1007/s001250051260
-
Deinum J, Ronn B, Mathiesen E, Derkx FH, Hop WC, Schalekamp MA. Increase in serum prorenin precedes onset of microalbuminuria in patients with insulindependent diabetes mellitus. Diabetologia 1999;42: 1006-1010. (Pubitemid 29369610)
-
(1999)
Diabetologia
, vol.42
, Issue.8
, pp. 1006-1010
-
-
Deinum, J.1
Ronn, B.2
Mathiesen, E.3
Derkx, F.H.M.4
Hop, W.C.J.5
Schalekamp, M.A.D.H.6
-
13
-
-
0036266596
-
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
-
DOI 10.1172/JCI200214276
-
Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer J-D. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002;109: 1417-1427. (Pubitemid 34596167)
-
(2002)
Journal of Clinical Investigation
, vol.109
, Issue.11
, pp. 1417-1427
-
-
Nguyen, G.1
Delarue, F.2
Burckle, C.3
Bouzhir, L.4
Giller, T.5
Sraer, J.-D.6
-
14
-
-
9644283069
-
Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin
-
DOI 10.1172/JCI200421398
-
Ichihara A, Hayashi M, Kaneshiro Y, Suzuki F, Nakagawa T, Tada Y, Koura Y, Nishiyama A, Okada H, Uddin MN, Nabi AH, Ishida Y, Inagami T, Saruta T. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the 'handle' region for nonproteolytic activation of prorenin. J Clin Invest 2004;114: 1128-1135. (Pubitemid 39578702)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.8
, pp. 1128-1135
-
-
Ichihara, A.1
Hayashi, M.2
Kaneshiro, Y.3
Suzuki, F.4
Nakagawa, T.5
Tada, Y.6
Koura, Y.7
Nishiyama, A.8
Okada, H.9
Uddin, M.N.10
Nabi, A.H.M.N.11
Ishida, Y.12
Inagami, T.13
Saruta, T.14
-
15
-
-
34447272037
-
Regression of nephropathy developed in diabetes by (pro)renin receptor blockade
-
DOI 10.1681/ASN.2006080820
-
Takahashi H, Ichihara A, Kaneshiro Y, Inomata K, Sakoda M, Takemitsu T, Nishiyama A, Itoh H. Regression of nephropathy developed in diabetes by (Pro)renin receptor blockade. J Am Soc Nephrol 2007;18: 2054-2061. (Pubitemid 47041071)
-
(2007)
Journal of the American Society of Nephrology
, vol.18
, Issue.7
, pp. 2054-2061
-
-
Takahashi, H.1
Ichihara, A.2
Kaneshiro, Y.3
Inomata, K.4
Sakoda, M.5
Takemitsu, T.6
Nishiyama, A.7
Itoh, H.8
-
16
-
-
33745824649
-
Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice
-
DOI 10.1681/ASN.2006010029
-
Ichihara A, Suzuki F, Nakagawa T, Kaneshiro Y, Takemitsu T, Sakoda M, Nabi AH, Nishiyama A, Sugaya T, Hayashi M, Inagami T. Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice. J Am Soc Nephrol 2006;17: 1950-1961. (Pubitemid 44036179)
-
(2006)
Journal of the American Society of Nephrology
, vol.17
, Issue.7
, pp. 1950-1961
-
-
Ichihara, A.1
Suzuki, F.2
Nakagawa, T.3
Kaneshiro, Y.4
Takemitsu, T.5
Sakoda, M.6
Nurun Nabi, A.H.M.7
Nishiyama, A.8
Sugaya, T.9
Hayashi, M.10
Inagami, T.11
-
17
-
-
0036145348
-
Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: Effects of ACEI and ARB
-
DOI 10.1046/j.1523-1755.2002.00123.x
-
Onozato ML, Tojo A, Goto A, Fujita T, Wilcox CS. Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: effects of ACEI and ARB. Kidney Int 2002;61: 186-194. (Pubitemid 34075146)
-
(2002)
Kidney International
, vol.61
, Issue.1
, pp. 186-194
-
-
Onozato, M.L.1
Tojo, A.2
Goto, A.3
Fujita, T.4
Wilcox, C.S.5
-
18
-
-
44849114597
-
Aliskiren combined with losartan in type 2 diabetes and nephropathy
-
DOI 10.1056/NEJMoa0708379
-
Parving HH, Persson F, Lewis JB, Lewis EJ, Hollenberg NK. Aliskiren combined with losartan in type 2 diabetes and nephropathy. N Engl J Med 2008;358: 2433-2446. (Pubitemid 351793017)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.23
, pp. 2433-2446
-
-
Parving, H.-H.1
Persson, F.2
Lewis, J.B.3
Lewis, E.J.4
Hollenberg, N.K.5
-
19
-
-
39749088803
-
(Pro)renin receptor peptide inhibitor "Handle-region" peptide does not affect hypertensive nephrosclerosis in Goldblatt rats
-
DOI 10.1161/HYPERTENSIONAHA.107.101493
-
Muller DN, Klanke B, Feldt S, Cordasic N, Hartner A, Schmieder RE, Luft FC, Hilgers KF. (Pro)renin receptor peptide inhibitor 'handle-region' peptide does not affect hypertensive nephrosclerosis in Goldblatt rats. Hypertension 2008;51: 676-681. (Pubitemid 351301520)
-
(2008)
Hypertension
, vol.51
, Issue.3
, pp. 676-681
-
-
Muller, D.N.1
Klanke, B.2
Feldt, S.3
Cordasic, N.4
Hartner, A.5
Schmieder, R.E.6
Luft, F.C.7
Hilgers, K.F.8
-
20
-
-
42249089770
-
The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling
-
Feldt S, Maschke U, Dechend R, Luft FC, Muller DN. The putative (pro)renin receptor blocker HRP fails to prevent (pro)renin signaling. J Am Soc Nephrol 2008;19: 743-748.
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 743-748
-
-
Feldt, S.1
Maschke, U.2
Dechend, R.3
Luft, F.C.4
Muller, D.N.5
-
21
-
-
54049106595
-
Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet
-
Susic D, Zhou X, Frohlich ED, Lippton H, Knight M. Cardiovascular effects of prorenin blockade in genetically spontaneously hypertensive rats on normal and high-salt diet. Am J Physiol Heart Circ Physiol 2008;295: H1117-H1121.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Susic, D.1
Zhou, X.2
Frohlich, E.D.3
Lippton, H.4
Knight, M.5
-
22
-
-
79952382489
-
Involvement of activated prorenin in the pathogenesis of slowly progressive nephropathy in the non-clipped kidney of two kidneys, one-clip hypertension
-
Ryuzaki M, Ichihara A, Oshima Y, Sakoda M, Kurauchi- Mito A, Narita T, Kinouchi K, Murohashi-Bokuda K, Nishiyama A, Itoh H. Involvement of activated prorenin in the pathogenesis of slowly progressive nephropathy in the non-clipped kidney of two kidneys, one-clip hypertension. Hypertens Res 2011;34: 301-307.
-
(2011)
Hypertens Res
, vol.34
, pp. 301-307
-
-
Ryuzaki, M.1
Ichihara, A.2
Oshima, Y.3
Sakoda, M.4
Kurauchi- Mito, A.5
Narita, T.6
Kinouchi, K.7
Murohashi-Bokuda, K.8
Nishiyama, A.9
Itoh, H.10
-
23
-
-
36849049298
-
Hypoxia and the HIF system in kidney disease
-
DOI 10.1007/s00109-007-0278-y, Special Issue (Ed. G. Semenza): Hypoxia and Human Disease
-
Nangaku M, Eckardt KU. Hypoxia and the HIF system in kidney disease. J Mol Med 2007;85: 1325-1330. (Pubitemid 50004091)
-
(2007)
Journal of Molecular Medicine
, vol.85
, Issue.12
, pp. 1325-1330
-
-
Nangaku, M.1
Eckardt, K.-U.2
-
24
-
-
77957695178
-
Aliskiren binds to renin and prorenin bound to (pro)renin receptor in vitro
-
Biswas KB, Nabi AH, Arai Y, Nakagawa T, Ebihara A, Ichihara A, Watanabe T, Inagami T, Suzuki F. Aliskiren binds to renin and prorenin bound to (pro)renin receptor in vitro. Hypertens Res 2010;33: 1053-1059.
-
(2010)
Hypertens Res
, vol.33
, pp. 1053-1059
-
-
Biswas, K.B.1
Nabi, A.H.2
Arai, Y.3
Nakagawa, T.4
Ebihara, A.5
Ichihara, A.6
Watanabe, T.7
Inagami, T.8
Suzuki, F.9
-
25
-
-
42349086752
-
Renin inhibition by aliskiren prevents atherosclerosis progression: Comparison with irbesartan, atenolol, and amlodipine
-
DOI 10.1161/HYPERTENSIONAHA.108.110932, PII 0000426820080500000012
-
Nussberger J, Aubert JF, Bouzourene K, Pellegrin M, Hayoz D, Mazzolai L. Renin inhibition by aliskiren prevents atherosclerosis progression: comparison with irbesartan, atenolol, and amlodipine. Hypertension 2008;51: 1306-1311. (Pubitemid 351555942)
-
(2008)
Hypertension
, vol.51
, Issue.5
, pp. 1306-1311
-
-
Nussberger, J.1
Aubert, J.-F.2
Bouzourene, K.3
Pellegrin, M.4
Hayoz, D.5
Mazzolai, L.6
-
26
-
-
77951104782
-
Aliskiren inhibits intracellular angiotensin II levels without affecting (pro)renin receptor signals in human podocytes
-
Sakoda M, Ichihara A, Kurauchi-Mito A, Narita T, Kinouchi K, Murohashi-Bokuda K, Saleem MA, Nishiyama A, Suzuki F, Itoh H. Aliskiren inhibits intracellular angiotensin II levels without affecting (pro)renin receptor signals in human podocytes. Am J Hypertens 2010;23: 575-580.
-
(2010)
Am J Hypertens
, vol.23
, pp. 575-580
-
-
Sakoda, M.1
Ichihara, A.2
Kurauchi-Mito, A.3
Narita, T.4
Kinouchi, K.5
Murohashi-Bokuda, K.6
Saleem, M.A.7
Nishiyama, A.8
Suzuki, F.9
Itoh, H.10
-
27
-
-
78649929199
-
Impact of baseline renal function on the efficacy and safety of aliskiren added to losartan in patients withtype 2 diabetes and nephropathy
-
Persson F, Lewis JB, Lewis EJ, Rossing P, Hollenberg NK, Parving HH. Impact of baseline renal function on the efficacy and safety of aliskiren added to losartan in patients withtype 2 diabetes and nephropathy. Diabetes Care 2010;33: 2304-2309.
-
(2010)
Diabetes Care
, vol.33
, pp. 2304-2309
-
-
Persson, F.1
Lewis, J.B.2
Lewis, E.J.3
Rossing, P.4
Hollenberg, N.K.5
Parving, H.H.6
-
28
-
-
0032079560
-
Identification and characterization of a novel 9.2-kDa membrane sector- associated protein of vacuolar proton-ATPase from chromaffin granules
-
DOI 10.1074/jbc.273.18.10939
-
Ludwig J, Kerscher S, Brandt U, Pfeiffer K, Getlawi F, Apps DK, Schägger H. Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules. J Biol Chem 1998;273: 10939-10947. (Pubitemid 28204933)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.18
, pp. 10939-10947
-
-
Ludwig, J.1
Kerscher, S.2
Brandt, U.3
Pfeiffer, K.4
Getlawi, F.5
Apps, D.K.6
Schagger, H.7
-
29
-
-
77954756914
-
Physiology of the (pro) renin receptor: Wnt of change?
-
Sihn G, Rousselle A, Vilianovitch L, Burckle C, Bader M. Physiology of the (pro)renin receptor: Wnt of change? Kidney Int 2010;78: 246-256.
-
(2010)
Kidney Int
, vol.78
, pp. 246-256
-
-
Sihn, G.1
Rousselle, A.2
Vilianovitch, L.3
Burckle, C.4
Bader, M.5
-
30
-
-
75649120756
-
Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling
-
Cruciat CM, Ohkawara B, Acebron SP, Karaulanov E, Reinhard C, Ingelfinger D, Boutros M, Niehrs C. Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling. Science 2010;327: 459-463.
-
(2010)
Science
, vol.327
, pp. 459-463
-
-
Cruciat, C.M.1
Ohkawara, B.2
Acebron, S.P.3
Karaulanov, E.4
Reinhard, C.5
Ingelfinger, D.6
Boutros, M.7
Niehrs, C.8
-
31
-
-
4444220604
-
Identification of 315 genes essential for early zebrafish development
-
DOI 10.1073/pnas.0403929101
-
Amsterdam A, Nissen RM, Sun Z, Swindell EC, Farrington S, Hopkins N. Identification of 315 genes essential for early zebrafish development. Proc Natl Acad Sci USA 2004;101: 12792-12797. (Pubitemid 39167537)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.35
, pp. 12792-12797
-
-
Amsterdam, A.1
Nissen, R.M.2
Sun, Z.3
Swindell, E.C.4
Farrington, S.5
Hopkins, N.6
-
32
-
-
77954762963
-
The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes
-
Kinouchi K, Ichihara A, Sano M, Sun-Wada GH, Wada Y, Kurauchi-Mito A, Bokuda K, Narita T, Oshima Y, Sakoda M, Tamai Y, Sato H, Fukuda K, Itoh H. The (pro)renin receptor/ATP6AP2 is essential for vacuolar H+-ATPase assembly in murine cardiomyocytes. Circ Res 2010;107: 30-34.
-
(2010)
Circ Res
, vol.107
, pp. 30-34
-
-
Kinouchi, K.1
Ichihara, A.2
Sano, M.3
Sun-Wada, G.H.4
Wada, Y.5
Kurauchi-Mito, A.6
Bokuda, K.7
Narita, T.8
Oshima, Y.9
Sakoda, M.10
Tamai, Y.11
Sato, H.12
Fukuda, K.13
Itoh, H.14
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