Reduced glutathione concentrations are not decreased in red blood cells of patients with long term type 1-diabetes

Scandinavian Journal of Clinical and Laboratory Investigation

Volumn 71, Issue 2, 2011, Pages 108-111

  Sakhi, Amrit K ^a   Berg, Tore J ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

diabetes; erythrocytes; Glutathione; methylglyoxal derived hydroimidazolone MG H1

Indexed keywords

CREATININE; GLUCOSE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HEMOGLOBIN A1C; IMIDAZOLE DERIVATIVE; INSULIN; METHYLGLYOXAL; METHYLGLYOXAL DERIVED HYDROIMIDAZOLONE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; CROSS-SECTIONAL STUDY; DISEASE DURATION; ERYTHROCYTE; FEMALE; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY FUNCTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADULT; DIABETES MELLITUS, TYPE 1; ERYTHROCYTES; FEMALE; GLUTATHIONE; HUMANS; MALE; PYRUVALDEHYDE; TIME FACTORS;

EID: 79952391693     PISSN: 00365513     EISSN: 15027686     Source Type: Journal    
DOI: 10.3109/00365513.2010.536851     Document Type: Article

References (22)

1. West IC. Radicals and oxidative stress in diabetes. Diabet Med 2000;17:171-80. (Pubitemid 30212288)
2. Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I, Brownlee M. Normalizing mitochondrial super-oxide production blocks three pathways of hyperglycaemic damage. Nature 2000;404:787-90. (Pubitemid 30212409)
3. Franco R, Schoneveld OJ, Pappa A, Panayiotidis MI. The central role of glutathione in the pathophysiology of human diseases. Arch Physiol Biochem 2007;113:234-58.
4. Darmaun D, Smith SD, Sweeten S, Sager BK, Welch S, Mauras N. Evidence for accelerated rates of glutathione utili-zation and glutathione depletion in adolescents with poorly controlled type 1 diabetes. Diabetes 2005;54:190-6. (Pubitemid 40105112)
5. Jain SK, McVie R, Smith T. Vitamin E supplementation restores glutathione and malondialdehyde to normal concen-trations in erythrocytes of type 1 diabetic children. Diabetes Care 2000;23:1389-94.
6. Dominguez C, Ruiz E, Gussinye M, Carrascosa A. Oxidative stress at onset and in early stages of type 1 diabetes in children and adolescents. Diabetes Care 1998;21:1736-42. (Pubitemid 28449817)
7. McLellan AC, Thornalley PJ, Benn J, Sonksen PH. Glyox-alase system in clinical diabetes mellitus and correlation with diabetic complications. Clin Sci (Lond) 1994;87:21-9. (Pubitemid 24220267)
8. Jain SK, McVie R. Effect of glycemic control, race (white versus black), and duration of diabetes on reduced glutathi-one content in erythrocytes of diabetic patients. Metabolism 1994;43:306-9. (Pubitemid 24100499)
9. Hernandez-Marco R, Codoner-Franch P, Pons MS, Del C, V, Boix GL, Valls B, V. Oxidant/antioxidant status and hyper-filtration in young patients with type 1 diabetes mellitus. Pediatr Nephrol 2009;24:121-7.
10. Varvarovska J, Racek J, Stozicky F, Soucek J, Trefil L, Pomahacova R. Parameters of oxidative stress in children with Type 1 diabetes mellitus and their relatives. J Diabetes Complications 2003;17:7-10. (Pubitemid 36042785)
11. Cimbaljevic B, Vasilijevic A, Cimbaljevic S, Buzadzic B, Korac A, Petrovic V, Jankovic A, Korac B. Interrelationship of antioxidative status, lipid peroxidation, and lipid profile in insulin-dependent and non-insulin-dependent diabetic patients. Can J Physiol Pharmacol 2007;85:997-1003.
12. Hagglof B, Holmgren G, Falkmer S. Blood glutathione in various phases of insulin-dependent diabetes mellitus in children. Ups J Med Sci 1981;86:93-7. (Pubitemid 11092361)
13. Telci A, Cakatay U, Salman S, Satman I, Sivas A. Oxidative protein damage in early stage Type 1 diabetic patients. Diabetes Res Clin Pract 2000;50:213-23.
14. Stahlberg MR, Hietanen E. Glutathione and glutathione-metabolizing enzymes in the erythrocytes of healthy children and in children with insulin-dependent diabetes mellitus, juve-nile rheumatoid arthritis, coeliac disease and acute lympho-blastic leukaemia. Scand J Clin Lab Invest 1991;51:125-30.
15. Sakhi AK, Russnes KM, Smeland S, Blomhoff R, Gundersen TE. Simultaneous quantification of reduced and oxidized glu-tathione in plasma using a two-dimensional chromatographic system with parallel porous graphitized carbon columns cou-pled with fluorescence and coulometric electrochemical detec-tion. J Chromatogr A 2006;1104:179-89. (Pubitemid 43099890)
16. Kilhovd BK, Giardino I, Torjesen PA, Birkeland KI, Berg TJ, Thornalley PJ, Brownlee M, Hanssen KF. Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes. Metabolism 2003;52:163-7. (Pubitemid 36388837)
17. Santini SA, Marra G, Giardina B, Cotroneo P, Mordente A, Martorana GE, Manto A, Ghirlanda G. Defective plasma anti-oxidant defenses and enhanced susceptibility to lipid peroxida-tion in uncomplicated IDDM. Diabetes 1997;46:1853-8. (Pubitemid 27456421)
18. Leoncini G, Maresca M, Buzzi E. Inhibition of the glycolytic pathway by methylglyoxal in human platelets. Cell Biochem Funct 1989;7:65-70. (Pubitemid 19017832)
19. Kalapos MP, Garzo T, Antoni F, Mandl J. Accumulation of S-D-lactoylglutathione and transient decrease of glutathione level caused by methylglyoxal load in isolated hepatocytes. Biochim Biophys Acta 1992;1135:159-64.
20. Wild AC, Mulcahy RT. Regulation of gamma-glutamyl-cysteine synthetase subunit gene expression: insights into transcriptional control of antioxidant defenses. Free Radic Res 2000;32:281-301. (Pubitemid 30167475)
21. Eeg-Olofsson K, Cederholm J, Nilsson PM, Gudbjornsdottir S, Eliasson B. Glycemic and risk factor control in type 1 diabetes: results from 13,612 patients in a national diabetes register. Diabetes Care 2007;30:496-502. (Pubitemid 46354324)
22. Kim SK, Woodcroft KJ, Novak RF. Insulin and glucagon regu-lation of glutathione S-transferase expression in primary cul tured rat hepatocytes. J Pharmacol Exp Ther 2003;305:353-61. (Pubitemid 36373871)