Geranylated flavanone tomentodiplacone B inhibits proliferation of human monocytic leukaemia (THP-1) cells

British Journal of Pharmacology

Volumn 162, Issue 7, 2011, Pages 1534-1541

  Kollár, Peter ^a   Bárta, Tomáš ^b,c   Závalová, Veronika ^a   Šmejkal, Karel ^a   Hampl, Aleš ^b,c  

^a UNIVERSITY OF VETERINARY AND PHARMACEUTICAL SCIENCES   (Czech Republic)

^b MASARYK UNIVERSITY   (Czech Republic)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

antiproliferative effect; CDK2; cell cycle regulators; cyclins; flavonoids

Indexed keywords

4',5,7 TRIHYDROXY 3' METHOXY 6 [7 HYDROXY 3,7 DIMETHYL 2,5 OCTADIENYL]FLAVANONE; CYCLIN A2; CYCLIN DEPENDENT KINASE 2; CYCLIN E; CYCLIN E1; FLAVANONE DERIVATIVE; HISTONE H2AX; PROTEIN P21; PROTEIN P53; TOMENTODIPLACONE B; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL GROWTH; CELL PROLIFERATION; CELL STRESS; CELL VIABILITY; CONTROLLED STUDY; CYTOSTASIS; DNA DAMAGE; DOSE RESPONSE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MONOCYTIC LEUKEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANTICARCINOGENIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D; CYCLIN-DEPENDENT KINASE 2; CYCLINS; DOWN-REGULATION; FLAVANONES; G1 PHASE; HUMANS; LEUKEMIA, MONOCYTIC, ACUTE; MONOCYTES; MONOTERPENES; SIGNAL TRANSDUCTION;

EID: 79952370528     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01171.x     Document Type: Article

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