메뉴 건너뛰기




Volumn 57, Issue 4, 2011, Pages 546-554

A new quantitative PCR assay for the detection of hepatotoxigenic cyanobacteria

Author keywords

Cyanobacteria; Harmful algal bloom; Melt curve analysis; Microcystin; Nodularin; Quantitative PCR

Indexed keywords

MICROCYSTIN; NODULARIN;

EID: 79952359319     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2010.12.018     Document Type: Article
Times cited : (51)

References (46)
  • 1
    • 57649222535 scopus 로고    scopus 로고
    • Phenotypic and toxicological characterization of toxic Nodularia spumigena from a freshwater lake in Turkey
    • Akcaalan R., Marzur-Marzec H., Zalewska A., Albay M. Phenotypic and toxicological characterization of toxic Nodularia spumigena from a freshwater lake in Turkey. Harmful Algae 2009, 8:273-278.
    • (2009) Harmful Algae , vol.8 , pp. 273-278
    • Akcaalan, R.1    Marzur-Marzec, H.2    Zalewska, A.3    Albay, M.4
  • 2
    • 0028560013 scopus 로고
    • Use of a colorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins
    • An J., Carmichael W.W. Use of a colorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins. Toxicon 1994, 32:1495-1507.
    • (1994) Toxicon , vol.32 , pp. 1495-1507
    • An, J.1    Carmichael, W.W.2
  • 3
    • 0036946724 scopus 로고    scopus 로고
    • Monitoring changing toxigenicity of a cyanobacterial bloom by molecular methods
    • Baker J.A., Entsch B., Neilan B.A., McKay D.B. Monitoring changing toxigenicity of a cyanobacterial bloom by molecular methods. Appl. Environ. Microbiol. 2002, 68:6070-6076.
    • (2002) Appl. Environ. Microbiol. , vol.68 , pp. 6070-6076
    • Baker, J.A.1    Entsch, B.2    Neilan, B.A.3    McKay, D.B.4
  • 4
    • 0033754285 scopus 로고    scopus 로고
    • PCR bias in ecological analysis: a case study for quantitative Taq nuclease assays in analyses of microbial communities
    • Becker S., Boger P., Oehlmann R., Ernst A. PCR bias in ecological analysis: a case study for quantitative Taq nuclease assays in analyses of microbial communities. Appl. Environ. Microbiol. 2000, 66:4945-4953.
    • (2000) Appl. Environ. Microbiol. , vol.66 , pp. 4945-4953
    • Becker, S.1    Boger, P.2    Oehlmann, R.3    Ernst, A.4
  • 5
    • 0032891849 scopus 로고    scopus 로고
    • Genetic, morphological, and toxicological variation among globally distributed strains of Nodularia (cyanobacteria)
    • Bolch C.J.S., Orr P.T., Jones G., Blackburn S.I. Genetic, morphological, and toxicological variation among globally distributed strains of Nodularia (cyanobacteria). J. Phycol 1999, 35:339-355.
    • (1999) J. Phycol , vol.35 , pp. 339-355
    • Bolch, C.J.S.1    Orr, P.T.2    Jones, G.3    Blackburn, S.I.4
  • 6
    • 33644860874 scopus 로고    scopus 로고
    • Transposons inactivate biosynthesis of the nonribosomal peptide microcystin in naturally occurring Planktothrix spp
    • Christiansen G., Kurmayer R., Liu Q., Borner T. Transposons inactivate biosynthesis of the nonribosomal peptide microcystin in naturally occurring Planktothrix spp. Appl. Environ. Microbiol. 2006, 72:117-123.
    • (2006) Appl. Environ. Microbiol. , vol.72 , pp. 117-123
    • Christiansen, G.1    Kurmayer, R.2    Liu, Q.3    Borner, T.4
  • 7
    • 0037226538 scopus 로고    scopus 로고
    • Microcystin biosynthesis in planktothrix: genes, evolution, and manipulation
    • Christiansen G., Fastner J., Erhard M., Borner T., Dittmann E. Microcystin biosynthesis in planktothrix: genes, evolution, and manipulation. J. Bacteriol. 2003, 185:564-572.
    • (2003) J. Bacteriol. , vol.185 , pp. 564-572
    • Christiansen, G.1    Fastner, J.2    Erhard, M.3    Borner, T.4    Dittmann, E.5
  • 8
    • 0030723581 scopus 로고    scopus 로고
    • Insertional mutagenesis of a peptide synthetase gene that is responsible for hepatotoxin production in the cyanobacterium Microcystis aeruginosa PCC 7806
    • Dittmann E., Neilan B.A., Erhard M., von Dohren H., Borner T. Insertional mutagenesis of a peptide synthetase gene that is responsible for hepatotoxin production in the cyanobacterium Microcystis aeruginosa PCC 7806. Mol. Microbiol. 1997, 26:779-787.
    • (1997) Mol. Microbiol. , vol.26 , pp. 779-787
    • Dittmann, E.1    Neilan, B.A.2    Erhard, M.3    von Dohren, H.4    Borner, T.5
  • 11
    • 0031106797 scopus 로고    scopus 로고
    • Isolation and toxicity of Cylindrospermopsis raciborskii from an ornamental lake
    • Hawkins P.R., Chandrasena N.R., Jones G.J., Humpage A.R., Falconer I.R. Isolation and toxicity of Cylindrospermopsis raciborskii from an ornamental lake. Toxicon 1997, 35:341-346.
    • (1997) Toxicon , vol.35 , pp. 341-346
    • Hawkins, P.R.1    Chandrasena, N.R.2    Jones, G.J.3    Humpage, A.R.4    Falconer, I.R.5
  • 12
    • 45549083918 scopus 로고    scopus 로고
    • Toxin types, toxicokinetics and toxicodynamics
    • Humpage A. Toxin types, toxicokinetics and toxicodynamics. Adv. Exp. Med. Biol. 2008, 619:383-415.
    • (2008) Adv. Exp. Med. Biol. , vol.619 , pp. 383-415
    • Humpage, A.1
  • 13
  • 14
    • 32344445955 scopus 로고    scopus 로고
    • Molecular identification and evolution of the cyclic peptide hepatotoxins, microcystin and nodularin, synthetase genes in three orders of cyanobacteria
    • Jungblut A.D., Neilan B.A. Molecular identification and evolution of the cyclic peptide hepatotoxins, microcystin and nodularin, synthetase genes in three orders of cyanobacteria. Arch. Microbiol. 2006, 185:107-114.
    • (2006) Arch. Microbiol. , vol.185 , pp. 107-114
    • Jungblut, A.D.1    Neilan, B.A.2
  • 16
    • 37049080007 scopus 로고
    • Extraction and high-performance liquid chromatographic method for the determination of microcystins in raw and treated waters
    • Lawton L.A., Edwards C., Codd G.A. Extraction and high-performance liquid chromatographic method for the determination of microcystins in raw and treated waters. Analyst 1994, 119:1525-1530.
    • (1994) Analyst , vol.119 , pp. 1525-1530
    • Lawton, L.A.1    Edwards, C.2    Codd, G.A.3
  • 17
    • 0035298795 scopus 로고    scopus 로고
    • Radioreceptor assays for sensitive detection and quantitation of saxitoxin and its analogues from strains of the freshwater cyanobacterium, Anabaena circinalis
    • Llewellyn L.E., Negri A.P., Doyle J., Baker P.D., Beltran E.C., Neilan B.A. Radioreceptor assays for sensitive detection and quantitation of saxitoxin and its analogues from strains of the freshwater cyanobacterium, Anabaena circinalis. Environ. Sci. Technol. 2001, 35:1445-1451.
    • (2001) Environ. Sci. Technol. , vol.35 , pp. 1445-1451
    • Llewellyn, L.E.1    Negri, A.P.2    Doyle, J.3    Baker, P.D.4    Beltran, E.C.5    Neilan, B.A.6
  • 19
    • 0025635610 scopus 로고
    • Tautomycin from the bacterium Streptomyces verticitlatus: another potent and specific inhibitor of protein phosphatases 1 and 2A
    • MacKintosh C., Klumpp S. Tautomycin from the bacterium Streptomyces verticitlatus: another potent and specific inhibitor of protein phosphatases 1 and 2A. FEBS Lett. 1990, 277:137-140.
    • (1990) FEBS Lett. , vol.277 , pp. 137-140
    • MacKintosh, C.1    Klumpp, S.2
  • 20
    • 0035189249 scopus 로고    scopus 로고
    • A time-resolved fluoroimmunometric assay for the detection of microcystins, cyanobacterial peptide hepatotoxins
    • Mehto P., Ankelo M., Hinkkanen A., Mikhailov A., Eriksson J.E., Spoof L., Meriluoto J. A time-resolved fluoroimmunometric assay for the detection of microcystins, cyanobacterial peptide hepatotoxins. Toxicon 2001, 39:831-836.
    • (2001) Toxicon , vol.39 , pp. 831-836
    • Mehto, P.1    Ankelo, M.2    Hinkkanen, A.3    Mikhailov, A.4    Eriksson, J.E.5    Spoof, L.6    Meriluoto, J.7
  • 21
    • 8744313964 scopus 로고    scopus 로고
    • Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins
    • Moffitt M.C., Neilan B.A. Characterization of the nodularin synthetase gene cluster and proposed theory of the evolution of cyanobacterial hepatotoxins. Appl. Environ. Microbiol. 2004, 70:6353-6362.
    • (2004) Appl. Environ. Microbiol. , vol.70 , pp. 6353-6362
    • Moffitt, M.C.1    Neilan, B.A.2
  • 22
    • 0035868628 scopus 로고    scopus 로고
    • On the presence of peptide synthetase and polyketide synthase genes in the cyanobacterial genus Nodularia
    • Moffitt M.C., Neilan B.A. On the presence of peptide synthetase and polyketide synthase genes in the cyanobacterial genus Nodularia. FEMS Microbiol. Lett. 2001, 196:207-214.
    • (2001) FEMS Microbiol. Lett. , vol.196 , pp. 207-214
    • Moffitt, M.C.1    Neilan, B.A.2
  • 23
    • 0036146824 scopus 로고    scopus 로고
    • Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set
    • Nadkarni M.A., Martin F.E., Jacques N.A., Hunter N. Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set. Microbiology 2002, 148:257-266.
    • (2002) Microbiology , vol.148 , pp. 257-266
    • Nadkarni, M.A.1    Martin, F.E.2    Jacques, N.A.3    Hunter, N.4
  • 24
    • 0029050366 scopus 로고
    • Identification and phylogenetic analysis of toxigenic cyanobacteria by multiplex randomly amplified polymorphic DNA PCR
    • Neilan B.A. Identification and phylogenetic analysis of toxigenic cyanobacteria by multiplex randomly amplified polymorphic DNA PCR. Appl. Environ. Microbiol. 1995, 61:2286-2291.
    • (1995) Appl. Environ. Microbiol. , vol.61 , pp. 2286-2291
    • Neilan, B.A.1
  • 26
    • 0028871685 scopus 로고
    • Genetic diversity and phylogeny of toxic cyanobacteria determined by DNA polymorphisms within the phycocyanin locus
    • Neilan B.A., Jacobs D., Goodman A.E. Genetic diversity and phylogeny of toxic cyanobacteria determined by DNA polymorphisms within the phycocyanin locus. Appl. Environ. Microbiol. 1995, 61:3875-3883.
    • (1995) Appl. Environ. Microbiol. , vol.61 , pp. 3875-3883
    • Neilan, B.A.1    Jacobs, D.2    Goodman, A.E.3
  • 27
    • 0036191886 scopus 로고    scopus 로고
    • A PCR-based test to assess the potential for microcystin occurrence in channel catfish production ponds
    • Nonneman D., Zimba P.V. A PCR-based test to assess the potential for microcystin occurrence in channel catfish production ponds. J. Phycol 2002, 38:230-233.
    • (2002) J. Phycol , vol.38 , pp. 230-233
    • Nonneman, D.1    Zimba, P.V.2
  • 28
    • 77649233502 scopus 로고    scopus 로고
    • Detection of various freshwater cyanobacterial toxins using ultra-performance liquid chromatography tandem mass spectrometry
    • Oehrle S.A., Southwell B., Westrick J. Detection of various freshwater cyanobacterial toxins using ultra-performance liquid chromatography tandem mass spectrometry. Toxicon 2010, 55:965-972.
    • (2010) Toxicon , vol.55 , pp. 965-972
    • Oehrle, S.A.1    Southwell, B.2    Westrick, J.3
  • 29
    • 71349085371 scopus 로고    scopus 로고
    • Typing of toxinogenic Microcystis from environmental samples by multiplex PCR
    • Ouahid Y., Del Campo F.F. Typing of toxinogenic Microcystis from environmental samples by multiplex PCR. Appl. Microbiol. Biotech. 2009, 85:405-412.
    • (2009) Appl. Microbiol. Biotech. , vol.85 , pp. 405-412
    • Ouahid, Y.1    Del Campo, F.F.2
  • 30
    • 33646344739 scopus 로고    scopus 로고
    • Toxic Microcystis is widespread in Lake Erie: PCR detection of toxin genes and molecular characterization of associated cyanobacterial communities
    • Ouellette A.J.A., Handy S.M., Wilhelm S.W. Toxic Microcystis is widespread in Lake Erie: PCR detection of toxin genes and molecular characterization of associated cyanobacterial communities. Microb. Ecol. 2006, 51:154-165.
    • (2006) Microb. Ecol. , vol.51 , pp. 154-165
    • Ouellette, A.J.A.1    Handy, S.M.2    Wilhelm, S.W.3
  • 31
    • 0036430051 scopus 로고    scopus 로고
    • Detection of hepatotoxic Microcystis strains by PCR with intact cells from both culture and environmental samples
    • Pan H., Song L., Liu Y., Borner T. Detection of hepatotoxic Microcystis strains by PCR with intact cells from both culture and environmental samples. Arch. Microbiol. 2002, 178:421-427.
    • (2002) Arch. Microbiol. , vol.178 , pp. 421-427
    • Pan, H.1    Song, L.2    Liu, Y.3    Borner, T.4
  • 32
    • 46549087651 scopus 로고    scopus 로고
    • The molecular genetics of cyanobacterial toxicity as a basis for monitoring water quality and public health risk
    • Pearson L.A., Neilan B.A. The molecular genetics of cyanobacterial toxicity as a basis for monitoring water quality and public health risk. Cur. Opin. Biotech. 2008, 19:281-288.
    • (2008) Cur. Opin. Biotech. , vol.19 , pp. 281-288
    • Pearson, L.A.1    Neilan, B.A.2
  • 35
    • 33748762738 scopus 로고    scopus 로고
    • Detection of microcystin-producing cyanobacteria in Finnish lakes with genus-specific microcystin synthetase gene E (mcyE) PCR and associations with environmental factors
    • Rantala A., Rajaniemi-Wacklin P., Lyra C., Lepisto L., Rintala J., Mankiewicz-Boczek J., Sivonen K. Detection of microcystin-producing cyanobacteria in Finnish lakes with genus-specific microcystin synthetase gene E (mcyE) PCR and associations with environmental factors. Appl. Environ. Microbiol. 2006, 72:6101-6110.
    • (2006) Appl. Environ. Microbiol. , vol.72 , pp. 6101-6110
    • Rantala, A.1    Rajaniemi-Wacklin, P.2    Lyra, C.3    Lepisto, L.4    Rintala, J.5    Mankiewicz-Boczek, J.6    Sivonen, K.7
  • 38
    • 0018409915 scopus 로고
    • Generic assignments, strain histories and properties of pure cultures of cyanobacteria
    • Rippka R., Deruelles J., Waterbury J., Herdman M., Stanier R. Generic assignments, strain histories and properties of pure cultures of cyanobacteria. J. Gen. Microbiol. 1979, 111:1-61.
    • (1979) J. Gen. Microbiol. , vol.111 , pp. 1-61
    • Rippka, R.1    Deruelles, J.2    Waterbury, J.3    Herdman, M.4    Stanier, R.5
  • 39
    • 0026476023 scopus 로고
    • Two methyl ester derivatives of microcystins, cyclic heptapeptide hepatotoxins, isolated from Anabaena flos-aquae CYA 83/1
    • Sivonen K., Skulberg O.M., Namikoshi M., Evans W.R., Carmichael W.W., Rinehart K.L. Two methyl ester derivatives of microcystins, cyclic heptapeptide hepatotoxins, isolated from Anabaena flos-aquae CYA 83/1. Toxicon 1992, 30:1465-1471.
    • (1992) Toxicon , vol.30 , pp. 1465-1471
    • Sivonen, K.1    Skulberg, O.M.2    Namikoshi, M.3    Evans, W.R.4    Carmichael, W.W.5    Rinehart, K.L.6
  • 42
    • 0033780306 scopus 로고    scopus 로고
    • Structural organization of microcystin biosynthesis in Microcystis aeruginosa PCC7806: an integrated peptide-polyketide synthetase system
    • Tillett D., Dittmann E., Erhard M., von Dohren H., Borner T., Neilan B.A. Structural organization of microcystin biosynthesis in Microcystis aeruginosa PCC7806: an integrated peptide-polyketide synthetase system. Chem. Biol. 2000, 7:753-764.
    • (2000) Chem. Biol. , vol.7 , pp. 753-764
    • Tillett, D.1    Dittmann, E.2    Erhard, M.3    von Dohren, H.4    Borner, T.5    Neilan, B.A.6
  • 43
    • 2142860222 scopus 로고    scopus 로고
    • Quantitative real-time PCR for determination of microcystin synthetase E copy numbers for Microcystis and Anabaena in lakes
    • Vaitomaa J., Rantala A., Halinen K., Rouhiainen L., Tallberg P., Mokelke L., Sivonen K. Quantitative real-time PCR for determination of microcystin synthetase E copy numbers for Microcystis and Anabaena in lakes. Appl. Environ. Microbiol. 2003, 69:7289-7297.
    • (2003) Appl. Environ. Microbiol. , vol.69 , pp. 7289-7297
    • Vaitomaa, J.1    Rantala, A.2    Halinen, K.3    Rouhiainen, L.4    Tallberg, P.5    Mokelke, L.6    Sivonen, K.7
  • 44
    • 77954377976 scopus 로고    scopus 로고
    • Multiplex PCR for detection of microcystin-producing cyanobacteria from freshwater samples
    • Valério E., Chambel L., Paulino S., Faria N., Pereira P., Tenreiro R. Multiplex PCR for detection of microcystin-producing cyanobacteria from freshwater samples. Environ. Toxicol. 2010, 25:251-260.
    • (2010) Environ. Toxicol. , vol.25 , pp. 251-260
    • Valério, E.1    Chambel, L.2    Paulino, S.3    Faria, N.4    Pereira, P.5    Tenreiro, R.6
  • 45
    • 0024244213 scopus 로고
    • Toxins contained in Microcystis species of cyanobacteria (blue-green algae)
    • Watanabe M.F., Oishi S., Harda K.I., Matsuura K., Kawai H., Suzuki M. Toxins contained in Microcystis species of cyanobacteria (blue-green algae). Toxicon 1988, 26:1017-1025.
    • (1988) Toxicon , vol.26 , pp. 1017-1025
    • Watanabe, M.F.1    Oishi, S.2    Harda, K.I.3    Matsuura, K.4    Kawai, H.5    Suzuki, M.6
  • 46
    • 33744965454 scopus 로고    scopus 로고
    • Cyanobacterial peptides - nature's own combinatorial biosynthesis
    • Welker M., von Dohren H. Cyanobacterial peptides - nature's own combinatorial biosynthesis. FEMS Microbiol. Rev. 2006, 30:530-563.
    • (2006) FEMS Microbiol. Rev. , vol.30 , pp. 530-563
    • Welker, M.1    von Dohren, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.