-
1
-
-
33749324118
-
Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade
-
Freeman GJ, Wherry EJ, Ahmed R, Sharpe AH, (2006) Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. J Exp Med 203: 2223-2227.
-
(2006)
J Exp Med
, vol.203
, pp. 2223-2227
-
-
Freeman, G.J.1
Wherry, E.J.2
Ahmed, R.3
Sharpe, A.H.4
-
2
-
-
41149109745
-
Signaling defects in anti-tumor T cells
-
Frey AB, Monu N, (2008) Signaling defects in anti-tumor T cells. Immunol Rev 222: 192-205.
-
(2008)
Immunol Rev
, vol.222
, pp. 192-205
-
-
Frey, A.B.1
Monu, N.2
-
3
-
-
0030218942
-
Altered T cell receptor ligands trigger a subset of early T cell signals
-
Rabinowitz JD, Beeson C, Wülfing C, Tate K, Allen P, et al. (1996) Altered T cell receptor ligands trigger a subset of early T cell signals. Immunity 5: 125-135.
-
(1996)
Immunity
, vol.5
, pp. 125-135
-
-
Rabinowitz, J.D.1
Beeson, C.2
Wülfing, C.3
Tate, K.4
Allen, P.5
-
4
-
-
0028829736
-
Alterations in T cell receptor and signal transduction molecules in melanoma patients
-
Zea AH, Curti BD, Longo DL, Alvord WG, Strobl SL, et al. (1995) Alterations in T cell receptor and signal transduction molecules in melanoma patients. Clin Cancer Res 1: 1327-1335.
-
(1995)
Clin Cancer Res
, vol.1
, pp. 1327-1335
-
-
Zea, A.H.1
Curti, B.D.2
Longo, D.L.3
Alvord, W.G.4
Strobl, S.L.5
-
5
-
-
32044452015
-
IL-12 reverses anergy to T cell receptor triggering in human lung tumor-associated memory T cells
-
Broderick L, Brooks SP, Takita H, Baer AN, Bernstein JM, et al. (2006) IL-12 reverses anergy to T cell receptor triggering in human lung tumor-associated memory T cells. Clin Immunol 118: 159-169.
-
(2006)
Clin Immunol
, vol.118
, pp. 159-169
-
-
Broderick, L.1
Brooks, S.P.2
Takita, H.3
Baer, A.N.4
Bernstein, J.M.5
-
6
-
-
20944434107
-
Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers
-
Bronte V, Kasic T, Gri G, Gallana K, Borsellino G, et al. (2005) Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers. J Exp Med 201: 1257-1268.
-
(2005)
J Exp Med
, vol.201
, pp. 1257-1268
-
-
Bronte, V.1
Kasic, T.2
Gri, G.3
Gallana, K.4
Borsellino, G.5
-
7
-
-
0035874949
-
Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
-
Woo EY, Chu CS, Goletz TJ, Schlienger K, Yeh H, et al. (2001) Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res 61: 4766-4772.
-
(2001)
Cancer Res
, vol.61
, pp. 4766-4772
-
-
Woo, E.Y.1
Chu, C.S.2
Goletz, T.J.3
Schlienger, K.4
Yeh, H.5
-
8
-
-
70350537020
-
Simultaneous infiltration of polyfunctional effector and suppressor T cells into renal cell carcinomas
-
Attig S, Hennenlotter J, Pawelec G, Klein G, Koch SD, et al. (2009) Simultaneous infiltration of polyfunctional effector and suppressor T cells into renal cell carcinomas. Cancer Res 69: 8412-8419.
-
(2009)
Cancer Res
, vol.69
, pp. 8412-8419
-
-
Attig, S.1
Hennenlotter, J.2
Pawelec, G.3
Klein, G.4
Koch, S.D.5
-
9
-
-
4344671644
-
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance
-
Zippelius A, Batard P, Rubio-Godoy V, Bioley G, Lienard D, et al. (2004) Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res 64: 2865-2873.
-
(2004)
Cancer Res
, vol.64
, pp. 2865-2873
-
-
Zippelius, A.1
Batard, P.2
Rubio-Godoy, V.3
Bioley, G.4
Lienard, D.5
-
10
-
-
70349569569
-
Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
-
Ahmadzadeh M, Johnson LA, Heemskerk B, Wunderlich JR, Dudley ME, et al. (2009) Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired. Blood 114: 1537-1544.
-
(2009)
Blood
, vol.114
, pp. 1537-1544
-
-
Ahmadzadeh, M.1
Johnson, L.A.2
Heemskerk, B.3
Wunderlich, J.R.4
Dudley, M.E.5
-
11
-
-
77957664158
-
Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer
-
Zhang Y, Huang S, Gong D, Qin Y, Shen Q, (2010) Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer. Cell Mol Immunol 7: 389-395.
-
(2010)
Cell Mol Immunol
, vol.7
, pp. 389-395
-
-
Zhang, Y.1
Huang, S.2
Gong, D.3
Qin, Y.4
Shen, Q.5
-
12
-
-
33747762302
-
Membrane-associated TGF-beta1 inhibits human memory T cell signaling in malignant and nonmalignant inflammatory microenvironments
-
Broderick L, Bankert RB, (2006) Membrane-associated TGF-beta1 inhibits human memory T cell signaling in malignant and nonmalignant inflammatory microenvironments. J Immunol 177: 3082-3088.
-
(2006)
J Immunol
, vol.177
, pp. 3082-3088
-
-
Broderick, L.1
Bankert, R.B.2
-
13
-
-
70149115741
-
CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway
-
Gollmer K, Asperti-Boursin F, Tanaka Y, Okkenhaug K, Vanhaesebroeck B, et al. (2009) CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway. Blood 114: 580-588.
-
(2009)
Blood
, vol.114
, pp. 580-588
-
-
Gollmer, K.1
Asperti-Boursin, F.2
Tanaka, Y.3
Okkenhaug, K.4
Vanhaesebroeck, B.5
-
14
-
-
0037191792
-
Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
-
Stefanova II, Dorfman JR, Germain RN, (2002) Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes. Nature 420: 429-434.
-
(2002)
Nature
, vol.420
, pp. 429-434
-
-
Stefanova, I.I.1
Dorfman, J.R.2
Germain, R.N.3
-
15
-
-
3142688997
-
SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation
-
Chemnitz JM, Parry RV, Nichols KE, June CH, Riley JL, (2004) SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation. J Immunol 173: 945-954.
-
(2004)
J Immunol
, vol.173
, pp. 945-954
-
-
Chemnitz, J.M.1
Parry, R.V.2
Nichols, K.E.3
June, C.H.4
Riley, J.L.5
-
16
-
-
0030497720
-
Sequential involvement of Lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation
-
Binstadt BA, Brumbaugh KM, Dick CJ, Scharenberg AM, Williams BL, et al. (1996) Sequential involvement of Lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation. Immunity 5: 629-638.
-
(1996)
Immunity
, vol.5
, pp. 629-638
-
-
Binstadt, B.A.1
Brumbaugh, K.M.2
Dick, C.J.3
Scharenberg, A.M.4
Williams, B.L.5
-
17
-
-
55249094151
-
Two opposite signaling outputs are driven by the KIR2DL1 receptor in human CD4+ T cells
-
Fourmentraux-Neves E, Jalil A, Da Rocha S, Pichon C, Chouaib S, et al. (2008) Two opposite signaling outputs are driven by the KIR2DL1 receptor in human CD4+ T cells. Blood 112: 2381-2389.
-
(2008)
Blood
, vol.112
, pp. 2381-2389
-
-
Fourmentraux-Neves, E.1
Jalil, A.2
Da Rocha, S.3
Pichon, C.4
Chouaib, S.5
-
18
-
-
33847393154
-
Immunoregulatory role of B7-H1 in chronicity of inflammatory responses
-
Dong H, Chen X, (2006) Immunoregulatory role of B7-H1 in chronicity of inflammatory responses. Cell Mol Immunol 3: 179-187.
-
(2006)
Cell Mol Immunol
, vol.3
, pp. 179-187
-
-
Dong, H.1
Chen, X.2
-
19
-
-
33645736792
-
Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
-
Thompson RH, Kuntz SM, Leibovich BC, Dong H, Lohse CM, et al. (2006) Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up. Cancer Res 66: 3381-3385.
-
(2006)
Cancer Res
, vol.66
, pp. 3381-3385
-
-
Thompson, R.H.1
Kuntz, S.M.2
Leibovich, B.C.3
Dong, H.4
Lohse, C.M.5
-
20
-
-
77952343328
-
Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer
-
Matsuzaki J, Gnjatic S, Mhawech-Fauceglia P, Beck A, Miller A, et al. (2010) Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer. Proc Natl Acad Sci U S A 107: 7875-7880.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 7875-7880
-
-
Matsuzaki, J.1
Gnjatic, S.2
Mhawech-Fauceglia, P.3
Beck, A.4
Miller, A.5
-
21
-
-
36849015543
-
The sound of silence: modulating anergy in T lymphocytes
-
Saibil SD, Deenick EK, Ohashi PS, (2007) The sound of silence: modulating anergy in T lymphocytes. Curr Opin Immunol 19: 658-664.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 658-664
-
-
Saibil, S.D.1
Deenick, E.K.2
Ohashi, P.S.3
-
22
-
-
34248586083
-
Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers
-
Nakanishi J, Wada Y, Matsumoto K, Azuma M, Kikuchi K, et al. (2007) Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers. Cancer Immunol Immunother 56: 1173-1182.
-
(2007)
Cancer Immunol Immunother
, vol.56
, pp. 1173-1182
-
-
Nakanishi, J.1
Wada, Y.2
Matsumoto, K.3
Azuma, M.4
Kikuchi, K.5
-
23
-
-
34250177269
-
PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma
-
Thompson RH, Dong H, Lohse CM, Leibovich BC, Blute ML, et al. (2007) PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma. Clin Cancer Res 13: 1757-1761.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1757-1761
-
-
Thompson, R.H.1
Dong, H.2
Lohse, C.M.3
Leibovich, B.C.4
Blute, M.L.5
-
24
-
-
40249098634
-
Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes
-
Demotte N, Stroobant V, Courtoy PJ, Van Der Smissen P, Colau D, et al. (2008) Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes. Immunity 28: 414-424.
-
(2008)
Immunity
, vol.28
, pp. 414-424
-
-
Demotte, N.1
Stroobant, V.2
Courtoy, P.J.3
van der Smissen, P.4
Colau, D.5
-
25
-
-
2142646426
-
TGF-beta signaling and the fibrotic response
-
Leask A, Abraham DJ, (2004) TGF-beta signaling and the fibrotic response. FASEB J 18: 816-827.
-
(2004)
FASEB J
, vol.18
, pp. 816-827
-
-
Leask, A.1
Abraham, D.J.2
-
26
-
-
0035884996
-
Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines
-
Pathak MK, Yi T, (2001) Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines. J Immunol 167: 3391-3397.
-
(2001)
J Immunol
, vol.167
, pp. 3391-3397
-
-
Pathak, M.K.1
Yi, T.2
-
27
-
-
0037077135
-
Transcriptional mechanisms underlying lymphocyte tolerance
-
Macian F, Garcia-Cozar F, Im SH, Horton HF, Byrne MC, et al. (2002) Transcriptional mechanisms underlying lymphocyte tolerance. Cell 109: 719-731.
-
(2002)
Cell
, vol.109
, pp. 719-731
-
-
Macian, F.1
Garcia-Cozar, F.2
Im, S.H.3
Horton, H.F.4
Byrne, M.C.5
-
28
-
-
32044440789
-
Adaptive tolerance and clonal anergy are distinct biochemical states
-
Chiodetti L, Choi S, Barber DL, Schwartz RH, (2006) Adaptive tolerance and clonal anergy are distinct biochemical states. J Immunol 176: 2279-2291.
-
(2006)
J Immunol
, vol.176
, pp. 2279-2291
-
-
Chiodetti, L.1
Choi, S.2
Barber, D.L.3
Schwartz, R.H.4
-
29
-
-
70449727114
-
Reviving function in CD4+ T cells adapted to persistent systemic antigen
-
Rivas MN, Weatherly K, Hazzan M, Vokaer B, Dremier S, et al. (2009) Reviving function in CD4+ T cells adapted to persistent systemic antigen. J Immunol 183: 4284-4291.
-
(2009)
J Immunol
, vol.183
, pp. 4284-4291
-
-
Rivas, M.N.1
Weatherly, K.2
Hazzan, M.3
Vokaer, B.4
Dremier, S.5
-
30
-
-
77952557954
-
PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells
-
Good-Jacobson KL, Szumilas CG, Chen L, Sharpe AH, Tomayko MM, et al. (2010) PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells. Nat Immunol 11: 535-542.
-
(2010)
Nat Immunol
, vol.11
, pp. 535-542
-
-
Good-Jacobson, K.L.1
Szumilas, C.G.2
Chen, L.3
Sharpe, A.H.4
Tomayko, M.M.5
-
31
-
-
34848900497
-
Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs
-
Wong RM, Scotland RR, Lau RL, Wang C, Korman AJ, et al. (2007) Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs. Int Immunol 19: 1223-1234.
-
(2007)
Int Immunol
, vol.19
, pp. 1223-1234
-
-
Wong, R.M.1
Scotland, R.R.2
Lau, R.L.3
Wang, C.4
Korman, A.J.5
-
32
-
-
66949111877
-
PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients
-
Fourcade J, Kudela P, Sun Z, Shen H, Land SR, et al. (2009) PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients. J Immunol 182: 5240-5249.
-
(2009)
J Immunol
, vol.182
, pp. 5240-5249
-
-
Fourcade, J.1
Kudela, P.2
Sun, Z.3
Shen, H.4
Land, S.R.5
-
33
-
-
0036919858
-
Advances in the treatment of leishmaniasis
-
Sundar S, Rai M, (2002) Advances in the treatment of leishmaniasis. Curr Opin Infect Dis 15: 593-598.
-
(2002)
Curr Opin Infect Dis
, vol.15
, pp. 593-598
-
-
Sundar, S.1
Rai, M.2
-
34
-
-
74949125667
-
BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination
-
Derre L, Rivals JP, Jandus C, Pastor S, Rimoldi D, et al. (2010) BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination. J Clin Invest 120: 157-167.
-
(2010)
J Clin Invest
, vol.120
, pp. 157-167
-
-
Derre, L.1
Rivals, J.P.2
Jandus, C.3
Pastor, S.4
Rimoldi, D.5
-
35
-
-
0031936042
-
Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response
-
Delon J, Bercovici N, Liblau R, Trautmann A, (1998) Imaging antigen recognition by naive CD4+ T cells: compulsory cytoskeletal alterations for the triggering of an intracellular calcium response. Eur J Immunol 28: 716-729.
-
(1998)
Eur J Immunol
, vol.28
, pp. 716-729
-
-
Delon, J.1
Bercovici, N.2
Liblau, R.3
Trautmann, A.4
-
36
-
-
34249085248
-
CCR7 ligands control basal T cell motility within lymph node slices in a phosphoinositide 3-kinase- independent manner
-
Asperti-Boursin F, Real E, Bismuth G, Trautmann A, Donnadieu E, (2007) CCR7 ligands control basal T cell motility within lymph node slices in a phosphoinositide 3-kinase- independent manner. J Exp Med 204: 1167-1179.
-
(2007)
J Exp Med
, vol.204
, pp. 1167-1179
-
-
Asperti-Boursin, F.1
Real, E.2
Bismuth, G.3
Trautmann, A.4
Donnadieu, E.5
|