Mangiferin: A possible strategy for periodontal disease to therapy

Medical Hypotheses

Volumn 76, Issue 4, 2011, Pages 486-488

  Duang, Xing yu ^a   Wang, Qian ^a   Zhou, Xue dong ^b   Huang, Ding ming ^b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDIABETIC AGENT; ANTIOXIDANT; CATALASE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GAMMA INTERFERON; GLYCOSIDASE; IMMUNOMODULATING AGENT; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1 ANTIBODY; INTERLEUKIN 1; INTERLEUKIN 6; LIPOXIN A; MANGIFERIN; NITRIC OXIDE SYNTHASE; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHOLIPASE; PROSTAGLANDIN SYNTHASE; SUCRASE; SUCRASE ISOMALTASE; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; XANTHINE OXIDASE;

ALVEOLAR BONE LOSS; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BACTERIAL INFECTION; DRUG ACTIVITY; DRUG INHIBITION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; GLUCOSE BLOOD LEVEL; HUMAN; IMMUNOMODULATION; INHIBITION KINETICS; NONHUMAN; OXIDATIVE STRESS; PERIODONTITIS; PROTEIN EXPRESSION; TOOTH;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIOXIDANTS; HUMANS; PERIODONTITIS; RATS; XANTHONES;

BACTERIA (MICROORGANISMS); RATTUS;

EID: 79952317747     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2010.11.029     Document Type: Article

References (29)

1. Kinane D.F., Marshall G.J. Periodontal manifestations of systemic disease. Aust Dent J 2001, 46(1):2-12.
2. Kiran M., Arpak N., Unsal E., Erdogan M.F. The effect of improved periodontal health on metabolic control in type 2 diabetes mellitus. J Clin Periodontol 2005, 32(3):266-272.
3. Holmlund A., Holm G., Lind L. Severity of periodontal disease and number of remaining teeth are related to the prevalence of myocardial infarction and hypertension in a study based on 4,254 subjects. J Periodontol 2006, 77(7):1173-1178.
4. Salvi G.E., Lang N.P. Host response modulation in the management of periodontal diseases. J Clin Periodontol 2005, 32(Suppl. 6):108-129.
5. Sanchez G.M., Re L., Giuliani A., Nunez-Selles A.J., Davison G.P., Leon-Fernandez O.S., et al. Protective extract, mangiferin and selected antioxidants against TPA-induced biomolecules oxidation and peritoneal macrophage activation in mice. Pharmacol Res 2000, 42(6):565-573.
6. Ojewole J.A. Antiinflammatory, analgesic and hypoglycemic effects of Mangifera indica Linn. (Anacardiaceae) stem-bark aqueous extract. Methods Find Exp Clin Pharmacol 2005, 27(8):547-554.
7. Dar A., Faizi S., Naqvi S., et al. Analgesic and antioxidant activity of mangiferin and its derivatives: the structure activity relationship. Biol Pharm Bull 2005, 28(4):596-600.
8. Ichiki H., Miura T., Kubo M., et al. New antidiabetic compounds, mangiferin and its glucoside. Biol Pharm Bull 1998, 21(12):1389-1390.
9. Guha S., Ghosal S., Chattopadhyay U. Antitumor, immunomodulatory and anti-HIV effect of mangiferin, a naturally occurring glucosylxanthone. Chemotherapy 1996, 42(6):443-451.
10. Mahanonda R., Pichyangkul S. Toll-like receptors and their role in periodontal health and disease. Periodontology 2000 2007, 43:41-55.
11. Matthews J.B., Wright H.J., Roberts A., Ling-Mountford N., Cooper P.R., Chapple I.L. Neutrophil hyper-responsiveness in periodontitis. J Dent Res 2007, 86(8):718-722.
12. Gazivoda D., Dzopalic T., Bozic B., Tatomirovic Z., Brkic Z., Colic M. Production of proinflammatory and immunoregulatory cytokines by inflammatory cells from periapical lesions in culture. J Oral Pathol Med 2009, 38(7):605-611.
13. 2+-citrate-induced lipoperoxidation in isolated rat liver mitochondria. Pharmacol Res 2005, 51(5):427-435.
14. Andreu G.L., Delgado R., Velho J.A., Curti C., Vercesi A.E. Mangiferin, a natural occurring glucosyl xanthone, increases susceptibility of rat liver mitochondria to calcium-induced permeability transition. Arch Biochem Biophys 2005, 439(2):184-193.
15. Leiro J.M., Alvarez E., Arranz J.A., Siso I.G., Orallo F. In vitro effects of mangiferin on superoxide concentrations and expression of the inducible nitric oxide synthase, tumor necrosis factor-α and transforming growth factor-β genes. Biochem Pharmacol 2003, 65(8):1361-1371.
16. Gottlieb M., Leal-Campanario R., Campos-Esparza M.R. Neuroprotection by two polyphenols following excitotoxicity and experimental ischemia. Neurobiol Dis 2006, 23(2):374-386.
17. Atlante A., Calissano P., Bobba A., Giannattasio S., Marra E., Passarella S. Glutamate neurotoxicity, oxidative stress and mitochondria. FEBS Lett 2001, 497(1):1-5.
18. Rajendran P., Ekambaram G., Sakthisekaran D. Cytoprotective effect of mangiferin on benzo(a)pyrene-induced lung carcinogenesis in swiss albino mice. Basic Clin Pharmacol Toxicol 2008, 103(2):137-142.
19. Muruganandan S., Gupta S., Kataria M., Lal J., Gupta P.K. Mangiferin protects the streptozotocin-induced oxidative damage to cardiac and renal tissues in rats. Toxicology 2002, 176(3):165-174.
20. Garrido G., Blanco-Molina M., Sancho R., Macho A., Delgado R., Munoz E. An aqueous stem bark extract of Mangifera indica (Vimang) inhibits T cell proliferation and TNF-induced activation of nuclear transcription factor NF-kappa B. Phytother Res 2005, 19(3):211-215.
21. Sarkar A., Sreenivasan Y., Ramesh G.T., Manna S.K. Beta-d-glucoside suppresses tumor necrosis factor-induced activation of nuclear transcription factor kappa B but potentiates apoptosis. J Biol Chem 2004, 279(32):33768-33781.
22. Moon Y., Pestka J.J. Vomitoxin-induced cyclooxygenase-2 gene expression in macrophages mediated by activation of ERK and p38 but not JNK mitogen-activated protein kinases. Toxicol Sci 2002, 69(2):373-382.
23. Lohinai Z., Stachlewitz R., Szekely A.D., Feher E., Dezsi L., Szabo C. Evidence for the expression of cyclooxygenase-2 enzyme in periodontitis. Life Sci 2001, 70(3):279-290.
24. Beltran A.E., Nunez N., Naranjo L., et al. VIMANG® y mangiferina inhiben la expresión de ICAM-1 en células endoteliales estimuladas con citocinas proinflamatorias. Rev Cubana Invest Bioméd 2003, 22(3):164-172.
25. Carvalho R.R., Pellizzon C.H., Justulin L., et al. Effect of mangiferin on the development of periodontal disease: involvement of lipoxin A4, anti-chemotaxic action in leukocyte rolling. Chem Biol Interact 2009, 179(2-3):344-350.
26. Bage T., Lindberg J., Lundeberg J., Modeer T., Yucel-Lindberg T. Signal pathways JNK and NF-kappa B, identified by global gene expression profiling, are involved in regulation of TNF alpha-induced mPGES-1 and COX-2 expression in gingival fibroblasts. BMC Genomics 2010, 11:241.
27. Yoshikawa M., Nishida N., Shimoda H., Takada M., Kawahara Y., Matsuda H. Polyphenol constituents from salacia species: quantitative analysis of mangiferin with glucosidase and aldose reductase inhibitory activities. Yakugaku Zasshi 2001, 121(5):371-378.
28. Muruganandan S., Srinivasan K., Gupta S., Gupta P.K., Lal J. Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats. J Ethnopharmacol 2005, 97(3):497-500.
29. Bairy I., Reeja S., Siddharth, Rao P.S., Bhat M., Shivananda P.G. Evaluation of antibacterial activity of Mangifera indica on anaerobic dental microglora based on in vivo studies. Indian J Pathol Microbiol 2002, 45(3):307-310.