Cytoprotective effect of mangiferin on benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice

Basic and Clinical Pharmacology and Toxicology

Volumn 103, Issue 2, 2008, Pages 137-142

  Rajendran, Peramaiyan ^a   Ekambaram, Ganapathy ^a   Sakthisekaran, Dhanapal ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BENZO[A]PYRENE; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MANGIFERIN; POLYPHENOL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; LUNG CARCINOGENESIS; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TREATMENT RESPONSE;

ANIMALS; ANTICARCINOGENIC AGENTS; BENZO(A)PYRENE; LIVER; LUNG; LUNG NEOPLASMS; MALE; MICE; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; XANTHONES;

ANIMALIA; MUS;

EID: 47649130056     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2008.00254.x     Document Type: Article

References (46)

1. Georgiou E, Valeri R, Tzimagiorgis G, Anzel J, Krikelis D, Tsilikas C et al. Aberrant p16 promoter methylation among Greek lung cancer patients and smokers: correlation with smoking. Eur J Cancer Prev 2007 16 : 396 402.
2. Travis WD, Travis LB, Devesa SS. Lung cancer. Cancer 1995 75 : 191 202.
3. Yang J, Lam EWN, Hammad HM, Oberley TD, Oberley LW. Antioxidant enzyme levels in oral squamous cell carcinoma and normal human oral epithelium. J Oral Pathol Med 2002 31 : 71 7.
4. Mantovani G, Maccio A, Madeddu C, Mura L, Gramignano G, Lusso MR. Quantitative evaluation of oxidative stress, chronic inflammatory indices and leptin in cancer patients: correlation with stage and performance status. Int J Cancer 2002 98 : 84 91.
5. Bakan N, Taysi S, Yilmaz O, Bakan E, Kuşkay S, Uzun N et al. Glutathione peroxidase, glutathione reductase, Cu-Zn superoxide dismutase activities, glutathione, nitric oxide, and malondialdehyde concentrations in serum of patients with chronic lymphocytic leukaemia. Clin Chem Acta 2003 338 : 143 9.
6. Mantovani G, Maccio A, Lai P, Massa E, Ghiani M, Santona MC. Cytokine activity in cancer-related anorexia/cachexia: role of megestrol acetate and medroxyprogesterone acetate. Semin Oncol 1998 25 : 45 52.
7. Gul M, Kutay FZ, Temocin S, Hanninen O. Cellular and clinical implications of glutathione. Indian J Exp Biol 2000 38 : 625 34.
8. Taysi S, Polat F, Gul M, Sari RA, Bakan E. Lipid peroxidation, some extracellular antioxidants, and antioxidant enzymes in serum of patients with rheumatoid arthritis. Rheumatol Int 2002 21 : 200 4.
9. Polat MF, Taysi S, Gul M, Cikman O, Yilmaz I, Bakan E et al. Oxidant/antioxidant status in blood of patients with malignant breast tumor and benign breast disease. Cell Biochem Funct 2002 20 : 327 31.
10. Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 2000 408 : 239 47.
11. Hockenhery DM, Oltavai ZN, Korsmeyer SJ. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993 75 : 241 51.
12. Johnson IT, Williamson G, Musk SR. Anticarcinogenic factors in plant foods: a new class of nutrients. Nut Rev 1994 7 : 175 204.
13. Dragsted LO, Strube M, Larsen JC. Cancer-protective factors in fruits and vegetables: biochemical and biological background. Pharmacol Toxicol 1993 72 : 116 35.
14. Yoshimi N, Matsunaga K, Katayama M, Yamada Y, Kuno T, Qiao Z et al. The inhibitory effects of mangiferin, a naturally occurring glucosylxanthone, in bowel carcinogenesis of male F344 rats. Cancer Lett 2001 163 : 163 70.
15. Quisumbing E. Medicinal Plants of the Philippines. Katha Publishing Co & JMC Press, Quezon, Philippines, 1978 538 41.
16. Nunez-Selles AJ, Velez Castro HT, Aguero-Aguero J, Gonzalez-Gonzalez J, Naddeo F, De Simone F et al. Isolation and quantitative analysis of phenolic antioxidants, free sugars, and polyols from mango (Mangifera indica L.) stem bark aqueous decoction used in Cuba as a nutritional supplement. J Agric Food Chem 2002 50 : 762 6.
17. Bhattacharya SK, Sanyal AK, Ghosal S. Monoamine oxidase-inhibiting activity of mangiferin isolated from canscora decussata. Naturwissenschaften 1972 59 : 651.
18. Guha S, Ghosal S, Chattopadhyay U. Antitumor, immunomodulatory and anti-HIV effect of mangiferin, a naturally occurring glucosylxanthone. Chemotherapy 1996 42 : 443 51.
19. Yoosook C, Bunyapraphatsara N, Boonyakiat Y, Kantasuk C. Anti-herpes simplex virus activities of crude water extracts of Thai medicinal plants. Phytomedicine 2000 6 : 411 9.
20. Li H, Miyahara T, Tezuka Y, Namba T, Nemoto N, Tonami S et al. The effect of kampo formulae on bone resorption in vitro and in vivo. I. Active constituents of Tsu-kan-gan. Biol Pharm Bull 1998 21 : 1322 6.
21. Moreira RR, Carlos IZ, Vilega W. Release of intermediate reactive Hydrogen peroxide by macrophage cells activated by natural products. Biol Pharm Bull 2001 24 : 201 4.
22. Sanchez GM, Re L, Giuliani A, Nuońez-Selles AJ, Davison GP, Leon-Fernandez OS. Protective effects of Mangifera indica L. extract, mangiferin and selected antioxidants against TPA-induced biomolecules oxidation and peritoneal macrophage activation in mice. Pharmacol Res 2000 42 : 565 73.
23. Leiro JM, A lvarez E, Arranz JA, Siso IG, Orallo F. In vitro effects of mangiferin on superoxide concentrations and expression of the inducible nitric oxide synthase, tumour necrosis factor-α and transforming growth factor-β genes. Biochem Pharmacol 2003 65 : 1361 71.
24. Mustafa M, Hacker AD, Husain MZ, Ospital JJ, Lee SD. Biochemical Effect of Environmental Pollutants in Animal Lungs. Ann Arbor Science, Ann Arbor, MI, 1977 59 96.
25. Johnson D, Lardy H. Isolation of liver and kidney mitochodria. Meth Enzymol 1967 10 : 94 6.
26. Rotruck JT, Pope AL, Ganther HE. Selenium: biochemical role as a component of glutathione peroxidase purification and assay. Science 1973 179 : 588 90.
27. Marklund S, Marklund G. Involvement of superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974 47 : 469 74.
28. Sinha AK. Colorimetric assay of catalase. Anal Biochem 1972 47 : 389 94.
29. Staal GEJ, Visser J, Veeger C. Purification and properties of glutathione reductase of human erythrocytes. Biochim Biophys Acta 1969 185 : 39 48.
30. Moron MS, DePierre JW, Manerwik KB. Levels of glutathione, glutathione reductase and glutathione-S-transferase activities in rat lung and liver. Biochim Biophys Acta 1979 582 : 67 8.
31. Nishikimi M, Appaji N, Yagi K. The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochem Biophys Res Commun 1972 46 : 849 54.
32. Wolf SP. Ferrous ion oxidation in presence of ferric ion indicator xylenol orange for measurement of hydroperoxides. Meth Enzymol 1994 23 : 180 9.
33. Gutteridge JM. Thiobarbituric acid-reactivity following iron-dependent free-radical damage to amino acids and carbohydrates. FEBS Lett 1981 128 : 343 6.
34. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951 193 : 265 75.
35. Watternberg LW. Chemoprevention of cancer. Cancer Res 1985 45 : 1 8.
36. Guner G, Islekel H, Oto O, Hazan E, Acikel U. Evaluation of some antioxidant enzymes in lung carcinoma tissue. Cancer Lett 1996 103 : 233 9.
37. Ravid A, Rocker D, Machlenkin A, Rotem C, Hochman A, Kessler-Icekson G et al. 1,25-Dihydroxyvitamin D3 enhances the susceptibility of breast cancer cells to doxorubicin-induced oxidative damage. Cancer Res 1999 59 : 862 7.
38. Masotti L, Casali E, Galeotti T. Lipid peroxidation in tumour cells. Free Radic Biol Med 1988 4 : 377 386.
39. Sun Y. Free radicals, antioxidant enzymes, and carcinogenesis. Free Radic Biol Med 1990 8 : 583 99.
40. Meister A, Anderson ME. Glutathione. Annu Rev Biochem 1983 52 : 711 60.
41. Amazzal L, Lapotre A, Quignon F, Bagrel D. Mangiferin protects against 1-methyl-4-phenylpyridinium toxicity mediated by oxidative stress in N2A cells. Neurosci Lett 2007 418 : 159 64.
42. Jones GM, Sanford KK, Parshad R, Gantt R, Price FM, Tarone RE. Influence of added catalase on chromosome stability and neoplastic transformation of mouse cells in culture. Br J Cancer 1985 52 : 583 90.
43. May JM. Is ascorbic acid an antioxidant for the plasma membrane? FASEB J 1999 13 : 995 1006.
44. Langemann H, Torhorst J, Kabiersch A, Krenger W, Honegger CG. Quantitative determination of water- and lipid-soluble antioxidants in neoplastic and non-neoplastic human breast tissue. Int J Cancer 1989 43 : 1169 73.
45. Das U. A radical approach to cancer. Med Sci Monit 2002 8 : RA79 92.
46. Galati G, Sabzevari O, Wilson JX, O'Brien PJ. Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics. Toxicology 2002 177 : 91 104.