Iron load and liver enzymes in 10- and 13-year-olds

Journal of Pediatric Gastroenterology and Nutrition

Volumn 52, Issue 3, 2011, Pages 333-338

  Okuda, Masayuki ^a   Sasaki, Satoshi ^b   Kunitsugu, Ichiro ^c   Sakurai, Ryuta ^c   Yoshitake, Norikazu ^c   Hobara, Tatsuya ^c  

^a YAMAGUCHI UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

cross sectional study; ferritin; insulin resistance; iron; transaminase

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; FERRITIN; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; IRON; LIPID;

ADOLESCENT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD ANALYSIS; BODY MASS; CHILD; CLINICAL ASSESSMENT; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GENDER; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN RESISTANCE; IRON BLOOD LEVEL; IRON INTAKE; IRON STORAGE; JAPANESE; LIPID BLOOD LEVEL; MALE; NORMAL HUMAN; PASSIVE SMOKING; PHYSICAL ACTIVITY; PRIORITY JOURNAL; SCHOOL CHILD; SMOKING;

ADOLESCENT; ALANINE TRANSAMINASE; CHILD; FEMALE; FERRITINS; GAMMA-GLUTAMYLTRANSFERASE; HUMANS; INSULIN RESISTANCE; IRON, DIETARY; JAPAN; LIVER; MALE; ODDS RATIO; TRANSAMINASES;

NICOTIANA TABACUM;

EID: 79952316328     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e318201aecc     Document Type: Article

References (47)

1. Murata M. Secular trends in growth and changes in eating patterns of Japanese children. Am J Clin Nutr 2000;72(suppl):1379S-83S.
2. Inokuchi M, Matsuo N, Takayama JI, et al. Official Japanese reports significantly underestimate prevalence of overweight in school children: inappropriate definition of standard weight and calculation of excess weight. Ann Hum Biol 2009;36:139-45.
3. Di Bonito P, Sanguigno E, Di Fraia T, et al. Association of elevated serum alanine aminotransferase with metabolic factors in obese children: sex-related analysis. Metabolism 2009;58:368-72.
4. González-Gil EM, Bueno-Lozano G, Bueno-Lozano O, et al. Serum transaminases concentrations in obese children and adolescents. J Physiol Biochem 2009;65:51-60.
5. Tominaga K, Fujimoto E, Suzuki K, et al. Prevalence of non-alcoholic fatty liver disease in children and relationship to metabolic syndrome, insulin resistance, and waist circumference. Env Health Prev Med 2009;14:142-9.
6. Fu C-C, Chen M-C, Li Y-M, et al. The risk factors for ultrasound-diagnosed non-alcoholic fatty liver disease among adolescents. Ann Acad Med Singapore 2009;38:15-21.
7. Tazawa Y, Noguchi H, Nishinomiya F, et al. Serum alanine aminotransferase activity in obese children. Acta Paediatr 1997;86:238-41. (Pubitemid 27135267)
8. Sartorio A, Del Col A, Agosti F, et al. Predictors of non-alcoholic fatty liver disease in obese children. Eur J Clin Nutr 2007;61:877-83. (Pubitemid 47040311)
9. Quirós-Tejeira R, Rivera CA, Ziba TT, et al. Risk for nonalcoholic fatty liver disease in Hispanic youth with BMI ≥95th percentile. J Pediatr Gastroenterol Nutr 2007;44:228-36. (Pubitemid 46175078)
10. Strauss RS, Barlow SE, Dietz W. Prevalence of abnormal serum aminotransferase values in overweight and obese adolescents. J Pediatr 2000;136:727-33. (Pubitemid 30415644)
11. Fraser A, Longnecker MP, Lawlor DA. Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999-2004. Gastroenterology 2007;133:1814-20.
12. Park HS, Han JH, Choi KM, et al. Relation between elevated serum alanine aminotransferase and metabolic syndrome in Korean adolescents. Am J Clin Nutr 2005;82:1046-51. (Pubitemid 43779763)
13. Guzzaloni G, Grugni G, Minocci A, et al. Liver steatosis in juvenile obesity: correlations with lipid profile, hepatic biochemical parameters and glycemic and insulinemic responses to an oral glucose tolerance test. Int J Obes 2000;24:772-6. (Pubitemid 30339276)
14. Lee D-H, Steffen LM, Jacobs DRJ. Association between serum (-glutamyltransferase and dietary factors: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Am J Clin Nutr 2004;79:600-5. (Pubitemid 41103903)
15. Strauss RS. Comparison of serum concentrations of alpha-tocopherol and beta-carotene in a cross-sectional sample of obese and nonobese children (NHANES III). J Pediatr 1999;134:160-5. (Pubitemid 29089038)
16. de Souza FI, Amancio OMS, Sarni ROS, et al. Non-alcoholic fatty liver disease in overweight children and its relationship with retinol serum levels. Int J Vitam Nutr Res 2008;78:27-32.
17. Aigner E, Hinz C, Steiner K, et al. Iron stores, liver transaminase levels and metabolic risk in healthy teenagers. Eur J Clin Invest 2010;40:155-63.
18. Suzuki K, Osaki Y, Wada K, et al. Decrease in Japanese adolescent drinking in 1996, 2000 and 2004 national surveys of Japanese junior and senior high school students. Jpn J Alcohol Drug Depend 2007;42:138-51.
19. Okuda M, Sugiyama S, Kunitsugu I, et al. Use of body mass index and percentage overweight cutoffs to screen Japanese children and adolescents for obesity-related risk factors. J Epidemiol 2010;20:46-53.
20. Okuda M, Kunitsugu I, Yoshitake N, et al. Variance in the transaminase levels over the body mass index spectrum in 10- and 13-year-olds. Pediatr Int 2010;52:813-9.
21. Cole TJ, Green PJ. Smoothing centile curves: the LMS method and penalized likelihood. Stat Med 1992;11:1305-19.
22. Inokuchi M, Hasegawa T, Anzo M, et al. Standardized centile curves of body mass index for Japanese children and adolescents based on the 1978-1981 national survey data. Ann Hum Biol 2006;33:444-53.
23. Study Group of Values in Children. Reference Values of Clinical Laboratory Data in Japanese Children. Tokyo: Japan Public Health Association; 1996.
24. Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and b-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28:412-9. (Pubitemid 15018832)
25. Sasaki S, Yanagibori R, Amano K. Self-administered diet history questionnaire developed for health education: a relative validation of the test-version by comparison with 3-day diet record in women. J Epidemiol 1998;8:203-15. (Pubitemid 128788430)
26. Okuda M, Sasaki S, Bando N, et al. Carotenoid, tocopherol, and fatty acid biomarkers and dietary intake estimated by using a brief self-administered diet history questionnaire for older Japanese children and adolescents. J Nutr Sci Vitaminol 2009;55:231-41.
27. Irwig MS, El-Sohemy A, Baylin A, et al. Frequent intake of tropical fruits that are rich in beta-cryptoxanthin is associated with higher plasma beta-cryptoxanthin concentrations in Costa Rican adolescents. J Nutr 2002;132:3161-7.
28. Neuhouser ML, Rock CL, Eldridge AL, et al. Serum concentrations of retinol, α-tocopherol and the carotenoids are influenced by diet, race and obesity in a sample of healthy adolescents. J Nutr 2001;131:2184-91. (Pubitemid 32720650)
29. Moilanen T, Räsänen L, Viikari J, et al. Correlation of serum fatty acid composition with dietary intake data in children and young adults. Ann Med 1992;24:67-70.
30. Tsuruta G, Tanaka N, Hongo M, et al. Nonalcoholic fatty liver disease in Japanese junior high school students: its prevalence and relationship to lifestyle habits. J Gastroenterol 2010;45:666-72.
31. Schwimmer JB, Dunn W, Norman GJ, et al. SAFETY Study: alanine aminotransoferase cutoff values are set too high for reliable detection of pediatric chronic liver disease. Gastroenterology 2010;138:1357-64.
32. Prati D, Taiolli E, Zanella A, et al. Updated definitions of healthy ranges for serum alanine aminotransferase levels. Ann Intern Med 2002;137:1-9. (Pubitemid 34705370)
33. World Health Organization. Iron Deficiency Anaemia Assessment, Prevention and Control: A Guide for Programme Managers. Geneva: World Health Organization; 2001.
34. de Benoist B, McLean E, Egli I, et al.Worldwide prevalence of anaemia 1993-2005: WHO global database on anaemia. In: WHO Library Cataloguing-in- Publication Data. Geneva: WHO Press; 2008.
35. Asakura K, Sasaki S, Murakami K, et al. Iron intake does not significantly correlate with iron deficiency among young Japanese women: a cross-sectional study. Public Health Nutr 2009;12:1373-83.
36. Papanikolaou G, Pantopoulos K. Iron metabolism and toxicity. Toxicol Appl Pharmacol 2005;202:199-211. (Pubitemid 40040559)
37. Tappel A. Heme of consumed red meat can act as a catalyst of oxidative damage and could initiate colon, breast and prostate cancers, heart disease and other diseases. Med Hypotheses 2007;68:562-4. (Pubitemid 46037986)
38. Kallianpur AR, Lee SA, Gao YT, et al. Dietary animal-derived iron and fat intake and breast cancer risk in the Shanghai Breast Cancer Study. Breast Cancer Res Treat 2008;107:123-32. (Pubitemid 350179598)
39. Bae Y-J, Yeon J-Y, Sung C-J, et al. Dietary intake and serum levels of iron in relation to oxidative stress in breast cancer patients. J Clin Biochem Nutr 2009;45:355-60.
40. Wu T, Sempos CT, Freudenheim JL, et al. Serum Iron, copper and zinc concentrations and risk of cancer mortality in US adults. Ann Epidemiol 2004;14:195-201. (Pubitemid 38249333)
41. Tuomainen T-P, Punnonen K, Nyyssönen K, et al. Association between body iron stores and the risk of acute myocardial infarction in men. Circulation 1998;97:1461-6. (Pubitemid 28191301)
42. Day CP, James OFW. Steatohepatitis: a tale of two "hits"? Gastroenterology 1998;114:842-5.
43. Farrel G, Larter CZ. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 2006;43:S99-112.
44. Chitturi S, George J. Interaction of iron, insulin resistance, and nonalcoholic steatohepatitis. Curr Gastroenterol Rep 2003;5:18-25. (Pubitemid 38899267)
45. Masini A, Ceccarelli D, Giovannini F, et al. Iron-induced oxidant stress leads to irreversible mitochondrial dysfunctions and fibrosis in the liver of chronic iron-dosed gerbis. The effect of silybin. J Bioenerg Biomembr 2000;32:175-82. (Pubitemid 30602304)
46. Imeryuz N, Tahan V, Sonsuz A, et al. Iron preloading aggravates nutritional steatohepatitis in rats by increasing apoptotic cell death. J Hepatol 2007;47:851-9. (Pubitemid 350051114)
47. Yamamoto M, Iwasa M, Iwata K, et al. Restriction of dietary calories, fat and iron improves non-alcoholic fatty liver disease. J Gastroenterol Hepatol 2007;22:498-503. (Pubitemid 46434977)