Ultrasound active nanoscaled lipid formulations for thrombus lysis

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 77, Issue 3, 2011, Pages 424-429

  Becker, Andreas ^a   Marxer, Elena ^a   Brüßler, Jana ^a   Hoormann, Anne Sophia ^a   Kuhnt, Daniela ^a   Bakowsky, Udo ^a   Nimsky, Christopher ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Contrast agent; Microbubbles; Nanomedicine; Thrombolysis; Ultrasonography

Indexed keywords

SONOVUE;

ARTERIAL PRESSURE; ARTICLE; BLOOD CLOT LYSIS; BLOOD CLOT RETRACTION; BRAIN ISCHEMIA; CONTROLLED STUDY; DIAGNOSTIC IMAGING; HUMAN; NANOANALYSIS; PHYSICOCHEMICAL MODEL; ULTRASOUND; WEIGHT REDUCTION;

EQUIPMENT DESIGN; FIBRINOLYSIS; FIBRINOLYTIC AGENTS; HUMANS; INTRACRANIAL THROMBOSIS; MICROBUBBLES; MICROSCOPY, ATOMIC FORCE; MODELS, BIOLOGICAL; NANOSTRUCTURES; PHOSPHOLIPIDS; SULFUR HEXAFLUORIDE; SURFACE PROPERTIES; THROMBOLYTIC THERAPY; ULTRASONIC THERAPY; ULTRASONICS;

EID: 79952315518     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.12.003     Document Type: Article

References (29)

1. P. Cintas, F. Nguyen, B. Boneu, V. Larrue, Enhancement of enzymatic fibrinolysis with 2-MHz ultrasound and microbubbles, J. Thromb. Haemost. 2 (7) (2004) 1163-1166.
2. V. Larrue, C. Viguier, Transcranial ultrasound combined with intravenous microbubbles and tissue plasminogen activator for acute ischemic stroke: a randomized controlled study, Stroke (2007) 472 (38).
3. E.C. Everbach, C.W. Francis, Cavitational mechanisms in ultrasound-accelerated thrombolysis at 1 MHz, Ultrasound Med. Biol. 26 (7) (2000) 1153-1160.
4. K.E. Morgan, J.S. Allen, P.A. Dayton, J.E. Chomas, A.L. Klibaov, K.W. Ferrara, Experimental and theoretical evaluation of microbubble behavior: effect of transmitted phase and bubble size, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 47 (6) (2000) 1494-1509. (Pubitemid 32076218)
5. M.W. Miller, D.L. Miller, A.A. Brayman, A review of in vitro bioeffects of inertial ultrasonic cavitation from a mechanistic perspective, Ultrasound. Med. Biol. 22 (9) (1996) 1131-1154. (Pubitemid 27024654)
6. S. Datta, C.C. Coussios, L.E. McAdory, J. Tan, T. Porter, G. De Courten-Myers, et al., Correlation of cavitation with ultrasound enhancement of thrombolysis, Ultrasound. Med. Biol. 32 (8) (2006) 1257-1267. (Pubitemid 44093792)
7. C.E. Brennen, Cavitation and Bubble Dynamics, Oxford University Press, 1995.
8. N. de Jong, L. Hoff, Ultrasound scattering properties of Albunex microspheres, Ultrasonics 31 (3) (1993) 175-181.
9. C.C. Church, The effects of an elastic solid surface layer on the radial pulsation of gas bubbles, J. Acoust. Soc. Am. (97) (1995) 1510.
10. A.A. Doinikov, P.A. Dayton, Spatio-temporal dynamics of an encapsulated gas bubble in an ultrasound field, J. Acoust. Soc. Am. 120 (2) (2006) 661-669. (Pubitemid 44213678)
11. S. Anabousi, M. Laue, C.M. Lehr, U. Bakowsky, C. Ehrhardt, Assessing transferrin modification of liposomes by atomic force microscopy and transmission electron microscopy, Eur. J. Pharm. Biopharm. 60 (2) (2005) 295-303. (Pubitemid 40804569)
12. H. Bakowsky, T. Richter, C. Kneuer, D. Hoekstra, U. Rothe, G. Bendas, et al., Adhesion characteristics and stability assessment of lectin-modified liposomes for site-specific drug delivery, Biochim. Biophys. Acta 1778 (1) (2008) 242-249.
13. V. Oberle, U. Bakowsky, I.S. Zuhorn, D. Hoekstra, Lipoplex formation under equilibrium conditions reveals a three-step mechanism, Biophys. J 79 (3) (2000) 1447-1454.
14. C. Kneuer, C. Ehrhardt, H. Bakowsky, M.N. Kumar, V. Oberle, C.M. Lehr, et al., The influence of physicochemical parameters on the efficacy of non-viral DNA transfection complexes: a comparative study, J. Nanosci. Nanotechnol. 6 (9-10) (2006) 2776-2782.
15. C. Kollmann, R.A. Bezemer, K.E. Fredfeldt, U.G. Schaarschmidt, C.J. Teirlinck, A test object for quality control of the instrument for doppler (duplex) ultrasonography, based on the draft IEC 61685 standard, Ultraschall. Med. 20 (6) (1999) 248-257. (Pubitemid 30066788)
16. C.W. Francis, S. Totterman, Magnetic resonance imaging of deep vein thrombi correlates with response to thrombolytic therapy, J. Thromb. Haemost. 73 (3) (1995) 386-391.
17. M. Loren, L.J. Garcia Frade, M.C. Torrado, J.L. Navarro, Thrombus age and tissue plasminogen activator mediated thrombolysis in rats, Thromb. Res. 56 (1) (1989) 67-75.
18. A.V. Alexandrov, R. Mikulik, M. Ribo, V.K. Sharma, A.Y. Lao, G. Tsivgoulis, et al., A pilot randomized clinical safety study of sonothrombolysis augmentation with ultrasound-activated perflutren-lipid microspheres for acute ischemic stroke, Stroke 39 (5) (2008) 1464-1469.
19. C.A. Molina, M. Ribo, M. Rubiera, J. Montaner, E. Santamarina, R. Delgado-Mederos, et al., Microbubble administration accelerates clot lysis during continuous 2-MHz ultrasound monitoring in stroke patients treated with intravenous tissue plasminogen activator, Stroke 37 (2) (2006) 425-429. (Pubitemid 43731999)
20. J. Pagola, M. Ribo, J. Alvarez-Sabin, M. Lange, M. Rubiera, C.A. Molina, Timing of recanalization after microbubble-enhanced intravenous thrombolysis in basilar artery occlusion, Stroke 38 (11) (2007) 2931-2934. (Pubitemid 350035685)
21. F. Perren, J. Loulidi, D. Poglia, T. Landis, R. Sztajzel, Microbubble potentiated transcranial duplex ultrasound enhances IV thrombolysis in acute stroke, J. Thromb. Thrombolysis 25 (2) (2008) 219-223. (Pubitemid 351583671)
22. A.F. Prokop, A. Soltani, R.A. Roy, Cavitational mechanisms in ultrasound-accelerated fibrinolysis, Ultrasound. Med. Biol. 33 (6) (2007) 924-933. (Pubitemid 46809775)
23. K. Mizushige, I. Kondo, K. Ohmori, K. Hirao, H. Matsuo, Enhancement of ultrasound-accelerated thrombolysis by echo contrast agents: dependence on microbubble structure, Ultrasound. Med. Biol. 25 (9) (1999) 1431-1437.
24. W.C. Culp, T.R. Porter, J. Lowery, F. Xie, P.K. Roberson, L. Marky, Intracranial clot lysis with intravenous microbubbles and transcranial ultrasound in swine, Stroke 35 (10) (2004) 2407-2411. (Pubitemid 39311272)
25. B. Krasovitski, E. Kimmel, Stability of an encapsulated bubble shell, Ultrasonics 44 (2) (2006) 216-220. (Pubitemid 43199482)
26. M.A. Borden, G. Pu, G.J. Runner, M.L. Longo, Surface phase behavior and microstructure of lipid/PEG-emulsifier monolayer-coated microbubbles, Colloids Surf. B: Biointerfaces 35 (3-4) (2004) 209-223.
27. D.H. Kim, M.J. Costello, P.B. Duncan, D. Needham, Mechanical properties and microstructure of polycrystalline phospholipid monolayer shells: novel solid microparticles, Langmuir 19 (20) (2003) 8455-8466.
28. D.B. Tata, F. Dunn, Thermodynamic method of B/A analysis of liposome suspensions: prediction via single relaxation theory, J. Ultrasound Med. 11 (8) (1992) 441-447. (Pubitemid 23049749)
29. A. Schroeder, Y. Avnir, S. Weisman, Y. Najajreh, A. Gabizon, Y. Talmon, et al., Controlling liposomal drug release with low frequency ultrasound: mechanism and feasibility, Langmuir 23 (7) (2007) 4019-4025. (Pubitemid 46581936)