Cytotoxicity of red fluorescent protein DsRed is associated with the suppression of Bcl-xL translation

FEBS Letters

Volumn 585, Issue 5, 2011, Pages 821-827

  Zhou, Jun ^a,b   Lin, Jian ^b,c   Zhou, Cuihong ^a,b   Deng, Xiaoyan ^a,b   Xia, Bin ^b,c  

^a BEIHANG UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

^c PEKING UNIVERSITY   (China)

Author keywords

Bcl xL; Cytotoxicity; DsRed; DsRed Express2; Red fluorescent protein; Turbo RFP

Indexed keywords

PROTEIN BCL 2; PROTEIN BCL XL; RED FLUORESCENT PROTEIN;

ARTICLE; CONTROLLED STUDY; CORAL; CYTOTOXICITY; DISCOSOMA; DOWN REGULATION; ENTACMAEA QUADRICOLOR; HELA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPECIES DIFFERENCE; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

BCL-X PROTEIN; CELL DEATH; DOWN-REGULATION; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; LUMINESCENT PROTEINS; MICROSCOPY, FLUORESCENCE; PROTEIN BIOSYNTHESIS; PROTEIN ISOFORMS;

ENTACMAEA QUADRICOLOR;

EID: 79952314024     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.02.013     Document Type: Article

References (21)

1. H. Mizuno, A. Sawano, P. Eli, H. Hama, and A. Miyawaki Red fluorescent protein from Discosoma as a fusion tag and a partner for fluorescence resonance energy transfer Biochemistry 40 2001 2502 2510 (Pubitemid 32171724)
2. M.V. Matz, A.F. Fradkov, Y.A. Labas, A.P. Savitsky, A.G. Zaraisky, M.L. Markelov, and S.A. Lukyanov Fluorescent proteins from nonbioluminescent Anthozoa species Nat. Biotechnol. 17 1999 969 973 (Pubitemid 29474851)
3. M.A. Wall, M. Socolich, and R. Ranganathan The structural basis for red fluorescence in the tetrameric GFP homolog DsRed Nat. Struct. Biol. 7 2000 1133 1138
4. G.S. Baird, D.A. Zacharias, and R.Y. Tsien Biochemistry, mutagenesis, and oligomerization of DsRed, a red fluorescent protein from coral Proc. Natl Acad. Sci. USA 97 2000 11984 11989
5. D.E. Strongin, B. Bevis, N. Khuong, M.E. Downing, R.L. Strack, K. Sundaram, B.S. Glick, and R.J. Keenan Structural rearrangements near the chromophore influence the maturation speed and brightness of DsRed variants Protein Eng. Des. Sel. 20 2007 525 534 (Pubitemid 350173522)
6. B.J. Bevis, and B.S. Glick Rapidly maturing variants of the Discosoma red fluorescent protein (DsRed) Nat. Biotechnol. 20 2002 83 87 (Pubitemid 34044920)
7. Y.G. Yanushevich, D.B. Staroverov, A.P. Savitsky, A.F. Fradkov, N.G. Gurskaya, M.E. Bulina, K.A. Lukyanov, and S.A. Lukyanov A strategy for the generation of non-aggregating mutants of Anthozoa fluorescent proteins FEBS Lett. 511 2002 11 14 (Pubitemid 34127814)
8. A.K. Hadjantonakis, S. Macmaster, and A. Nagy Embryonic stem cells and mice expressing different GFP variants for multiple non-invasive reporter usage within a single animal BMC Biotechnol. 2 2002 11
9. A.P. Xiang, F.F. Mao, W.Q. Li, D. Park, B.F. Ma, T. Wang, T.W. Vallender, E.J. Vallender, L. Zhang, J. Lee, J.A. Waters, X.M. Zhang, X.B. Yu, S.N. Li, and B.T. Lahn Extensive contribution of embryonic stem cells to the development of an evolutionarily divergent host Hum. Mol. Genetics 17 2008 27 37
10. R.L. Strack, D.E. Strongin, D. Bhattacharyya, W. Tao, A. Berman, H.E. Broxmeyer, R.J. Keenan, and B.S. Glick A non cytotoxic DsRed variant for whole-cell labeling Nat. Methods 5 2008 955 957
11. M. Fischer, I. Haase, E. Simmeth, G. Gerisch, and A. Muller-Taubenberger A brilliant monomeric red fluorescent protein to visualize cytoskeleton dynamics in Dictyostelium FEBS Lett. 577 2004 227 232 (Pubitemid 39452389)
12. D. Hockenbery, G. Nuñez, C. Milliman, R.D. Schreiber, and S.J. Korsmeyer Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death Nature 348 6299 1990 334 336 (Pubitemid 120029101)
13. G. Mercenne, S. Bernacchi, D. Richer, G. Bec, S. Henriet, J.C. Paillart, and R. Marquet HIV-1 Vif binds to APOBEC3G mRNA and inhibits its translation Nucleic Acids Res. 38 2010 633 646
14. J.M. Adams, and S. Cory The Bcl-2 protein family: arbiters of cell survival Science 281 1998 1322 1326 (Pubitemid 28406819)
15. B. Leber, J. Lin, and D.W. Andrews Still embedded together binding to membranes regulates Bcl-2 protein interactions Oncogene. 29 38 2010 5221 5230
16. T. Oltersdorf, S.W. Elmore, A.R. Shoemaker, R.C. Armstrong, D.J. Augeri, B.A. Belli, M. Bruncko, T.L. Deckwerth, J. Dinges, P.J. Hajduk, M.K. Joseph, S. Kitada, S.J. Korsmeyer, A.R. Kunzer, A. Letai, C. Li, M.J. Mitten, D.G. Nettesheim, S. Ng, P.M. Nimmer, J.M. O'Connor, A. Oleksijew, A.M. Petros, J.C. Reed, W. Shen, S.K. Tahir, C.B. Thompson, K.J. Tomaselli, B. Wang, M.D. Wendt, H. Zhang, S.W. Fesik, and S.H. Rosenberg An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature 435 2005 677 681 (Pubitemid 40825512)
17. J. Lin, Z. Zheng, Y. Li, W. Yu, W. Zhong, S. Tian, F. Zhao, X. Ren, J. Xiao, N. Wang, S. Liu, L. Wang, F. Sheng, Y. Chen, C. Jin, S. Li, and B. Xia A novel Bcl-XL inhibitor Z36 that induces autophagic cell death in Hela cells Autophagy 5 2009 314 320
18. E.M. Merzlyak, J. Goedhart, D. Shcherbo, M.E. Bulina, A.S. Shcheglov, A.F. Fradkov, A. Gaintzeva, K.A. Lukyanov, S. Lukyanov, T.W. Gadella, and D.M. Chudakov Bright monomeric red fluorescent protein with an extended fluorescence lifetime Nat. Methods 4 2007 555 557 (Pubitemid 47214772)
19. R.L. Strack, B. Hein, D. Bhattacharyya, S.W. Hell, R.J. Keenan, and B.S. Glick A rapidly maturing far-red derivative of DsRed-Express2 for whole-cell labeling Biochemistry 48 2009 8279 8281
20. R.L. Strack, D. Bhattacharyya, B.S. Glick, and R.J. Keenan Noncytotoxic orange and red/green derivatives of DsRed-Express2 for whole-cell labeling BMC Biol. 3 9 2009 32
21. H. Ai, S.G. Olenych, P. Wong, M.W. Davidson, and R.E. Campbell Hue-shifted monomeric variants of Clavularia cyan fluorescent protein: identification of the molecular determinants of color and applications in fluorescence imaging BMC Biol. 6 6 2008 13