Characterization of a novel human mast cell line that responds to stem cell factor and expresses functional FcεRI

Journal of Allergy and Clinical Immunology

Volumn 127, Issue 3, 2011, Pages 815-822.e5

  Laidlaw, Tanya M ^a,b   Steinke, John W ^c,d   Tiñana, Adrienne M ^d   Feng, Chunli ^a,b   Xing, Wei ^a,b   Lam, Bing K ^a,b   Paruchuri, Sailaja ^a,b   Boyce, Joshua A ^a,b   Borish, Larry ^c,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d UNIVERSITY OF VIRGINIA   (United States)

Author keywords

c kit; carboxypeptidase A3; Fc RI; Mast cell; stem cell factor; tryptase

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE; CARBOXYPEPTIDASE A; CATHEPSIN G; CD32 ANTIGEN; CD34 ANTIGEN; CD64 ANTIGEN; FC RECEPTOR; GROWTH FACTOR; HISTIDINE DECARBOXYLASE; IMATINIB; IMMUNOGLOBULIN E; INTERLEUKIN 3; INTERLEUKIN 6; LIPOCORTIN 5; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PEPTIDOLEUKOTRIENE; PROSTAGLANDIN D2; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; THROMBOXANE A2; TRYPTASE;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL GRANULE; CELL IMMORTALIZATION; CELL LINE; CELL PROLIFERATION; CELL STRAIN; CELL STRAIN LAD2; CELL STRAIN LUVA; CELL SURVIVAL; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; MAST CELL; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

EID: 79952310638     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.12.1101     Document Type: Article

References (34)

1. H. Ochi, W.M. Hirani, Q. Yuan, D.S. Friend, K.F. Austen, and J.A. Boyce T helper cell type 2 cytokine-mediated comitogenic responses and CCR3 expression during differentiation of human mast cells in vitro J Exp Med 190 1999 267 280 (Pubitemid 29354919)
2. H. Saito, M. Ebisawa, H. Tachimoto, M. Shichijo, K. Fukagawa, and K. Matsumoto Selective growth of human mast cells induced by Steel factor, IL-6, and prostaglandin E2 from cord blood mononuclear cells J Immunol 157 1996 343 350 (Pubitemid 26190566)
3. A.S. Kirshenbaum, J.P. Goff, T. Semere, B. Foster, L.M. Scott, and D.D. Metcalfe Demonstration that human mast cells arise from a progenitor cell population that is CD34(+), c-kit(+), and expresses aminopeptidase N (CD13) Blood 94 1999 2333 2342 (Pubitemid 29467681)
4. J.H. Butterfield, D. Weiler, G. Dewald, and G.J. Gleich Establishment of an immature mast cell line from a patient with mast cell leukemia Leuk Res 12 1988 345 355
5. A.S. Kirshenbaum, C. Akin, Y. Wu, M. Rottem, J.P. Goff, and M.A. Beaven Characterization of novel stem cell factor responsive human mast cell lines LAD 1 and 2 established from a patient with mast cell sarcoma/leukemia; activation following aggregation of FcepsilonRI or FcgammaRI Leuk Res 27 2003 677 682 (Pubitemid 36683255)
6. S. Guhl, M. Babina, A. Neou, T. Zuberbier, and M. Artuc Mast cell lines HMC-1 and LAD2 in comparison with mature human skin mast cells - drastically reduced levels of tryptase and chymase in mast cell lines Exp Dermatol 19 2010 845 847
7. F.H. Hsieh, B.K. Lam, J.F. Penrose, K.F. Austen, and J.A. Boyce T helper cell type 2 cytokines coordinately regulate immunoglobulin E-dependent cysteinyl leukotriene production by human cord blood-derived mast cells: profound induction of leukotriene C(4) synthase expression by interleukin 4 J Exp Med 193 2001 123 133 (Pubitemid 32060703)
8. B.K. Lam, J.F. Penrose, G.J. Freeman, and K.F. Austen Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4 Proc Natl Acad Sci U S A 91 1994 7663 7667 (Pubitemid 24238245)
9. J.A. Boyce, B.K. Lam, J.F. Penrose, D.S. Friend, S. Parsons, and W.F. Owen Expression of LTC4 synthase during the development of eosinophils in vitro from cord blood progenitors Blood 88 1996 4338 4347 (Pubitemid 26399182)
10. K. Hartmann, E. Wardelmann, Y. Ma, S. Merkelbach-Bruse, L.M. Preussner, and C. Woolery Novel germline mutation of KIT associated with familial gastrointestinal stromal tumors and mastocytosis Gastroenterology 129 2005 1042 1046 (Pubitemid 41242694)
11. T. Furitsu, T. Tsujimura, T. Tono, H. Ikeda, H. Kitayama, and U. Koshimizu Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product J Clin Invest 92 1993 1736 1744 (Pubitemid 23304537)
12. S. Hirota, K. Isozaki, Y. Moriyama, K. Hashimoto, T. Nishida, and S. Ishiguro Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors Science 279 1998 577 580 (Pubitemid 28067289)
13. M. Nakahara, K. Isozaki, S. Hirota, J. Miyagawa, N. Hase-Sawada, and M. Taniguchi A novel gain-of-function mutation of c-kit gene in gastrointestinal stromal tumors Gastroenterology 115 1998 1090 1095 (Pubitemid 28485599)
14. H. Nagata, A.S. Worobec, C.K. Oh, B.A. Chowdhury, S. Tannenbaum, and Y. Suzuki Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder Proc Natl Acad Sci U S A 92 1995 10560 10564
15. B.J. Longley Jr., D.D. Metcalfe, M. Tharp, X. Wang, L. Tyrrell, and S.Z. Lu Activating and dominant inactivating c-KIT catalytic domain mutations in distinct clinical forms of human mastocytosis Proc Natl Acad Sci U S A 96 1999 1609 1614 (Pubitemid 29098499)
16. H. Toru, C. Ra, S. Nonoyama, K. Suzuki, J. Yata, and T. Nakahata Induction of the high-affinity IgE receptor (Fc epsilon RI) on human mast cells by IL-4 Int Immunol 8 1996 1367 1373 (Pubitemid 26293886)
17. M. Yamaguchi, C.S. Lantz, H.C. Oettgen, I.M. Katona, T. Fleming, and I. Miyajima IgE enhances mouse mast cell Fc(epsilon)RI expression in vitro and in vivo: evidence for a novel amplification mechanism in IgE-dependent reactions J Exp Med 185 1997 663 672 (Pubitemid 27098151)
18. K. Furuichi, J. Rivera, and C. Isersky The receptor for immunoglobulin E on rat basophilic leukemia cells: effect of ligand binding on receptor expression Proc Natl Acad Sci U S A 82 1985 1522 1525 (Pubitemid 15120575)
19. H. Ochi, N.H. De Jesus, F.H. Hsieh, K.F. Austen, and J.A. Boyce IL-4 and -5 prime human mast cells for different profiles of IgE-dependent cytokine production Proc Natl Acad Sci U S A 97 2000 10509 10513
20. H.W. Wang, N. Tedla, A.R. Lloyd, D. Wakefield, and P.H. McNeil Mast cell activation and migration to lymph nodes during induction of an immune response in mice J Clin Invest 102 1998 1617 1626 (Pubitemid 28492230)
21. F. Thienemann, B.M. Henz, and M. Babina Regulation of mast cell characteristics by cytokines: divergent effects of interleukin-4 on immature mast cell lines versus mature human skin mast cells Arch Dermatol Res 296 2004 134 138 (Pubitemid 39150300)
22. D.E. Humphries, C.F. Nicodemus, V. Schiller, and R.L. Stevens The human serglycin gene. Nucleotide sequence and methylation pattern in human promyelocytic leukemia HL-60 cells and T-lymphoblast Molt-4 cells J Biol Chem 267 1992 13558 13563
23. L.B. Schwartz, R.A. Lewis, and K.F. Austen Tryptase from human pulmonary mast cells. Purification and characterization J Biol Chem 256 1981 11939 11943
24. A.M. Irani, S.M. Goldstein, B.U. Wintroub, T. Bradford, and L.B. Schwartz Human mast cell carboxypeptidase. Selective localization to MCTC cells J Immunol 147 1991 247 253
25. N.M. Schechter, A.M. Irani, J.L. Sprows, J. Abernethy, B. Wintroub, and L.B. Schwartz Identification of a cathepsin G-like proteinase in the MCTC type of human mast cell J Immunol 145 1990 2652 2661 (Pubitemid 20374592)
26. M.L. Fajt, S.E. Wenzel, and S. Balzar Altered levels and phenotype of intraepithelial mast cells in severe asthma J Allergy Clin Immunol 123 2009 S214
27. P.G. Woodruff, B. Modrek, D.F. Choy, G. Jia, A.R. Abbas, and A. Ellwanger T-helper type 2-driven inflammation defines major subphenotypes of asthma Am J Respir Crit Care Med 180 2009 388 395
28. R.H. Dougherty, S.S. Sidhu, K. Raman, M. Solon, O.D. Solberg, and G.H. Caughey Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma J Allergy Clin Immunol 125 2010 1046 1053 e8
29. Y. Okayama, A.S. Kirshenbaum, and D.D. Metcalfe Expression of a functional high-affinity IgG receptor, Fc gamma RI, on human mast cells: Up-regulation by IFN-gamma J Immunol 164 2000 4332 4339 (Pubitemid 30215096)
30. C. Akin, L.M. Scott, C.N. Kocabas, N. Kushnir-Sukhov, E. Brittain, and P. Noel Demonstration of an aberrant mast-cell population with clonal markers in a subset of patients with "idiopathic" anaphylaxis Blood 110 2007 2331 2333 (Pubitemid 47523152)
31. A. Tanaka, M. Konno, S. Muto, N. Kambe, E. Morii, and T. Nakahata A novel NF-kappaB inhibitor, IMD-0354, suppresses neoplastic proliferation of human mast cells with constitutively activated c-kit receptors Blood 105 2005 2324 2331 (Pubitemid 40387026)
32. W.L. Wang, M.E. Healy, M. Sattler, S. Verma, J. Lin, and G. Maulik Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571 Oncogene 19 2000 3521 3528 (Pubitemid 30487449)
33. L. Escribano, A. Orfao, B. Diaz-Agustin, J. Villarrubia, C. Cervero, and A. Lopez Indolent systemic mast cell disease in adults: immunophenotypic characterization of bone marrow mast cells and its diagnostic implications Blood 91 1998 2731 2736 (Pubitemid 28227522)
34. G.H. Schernthaner, A.W. Hauswirth, M. Baghestanian, H. Agis, M. Ghannadan, and C. Worda Detection of differentiation- and activation-linked cell surface antigens on cultured mast cell progenitors Allergy 60 2005 1248 1255 (Pubitemid 41297520)