Synthesis and biological activity of 2-(bis((1,3,4-oxadiazolyl/1,3,4- thiadiazolyl)methylthio)methylene)malononitriles

European Journal of Medicinal Chemistry

Volumn 46, Issue 4, 2011, Pages 1367-1373

  Padmavathi, V ^a   Dinneswara Reddy, G ^a   Nagi Reddy, S ^a   Mahesh, K ^a  

^a SRI VENKATESWARA UNIVERSITY   (India)

Author keywords

1,3,4 Oxadiazole; 1,3,4 Thiadiazole; Antimicrobial activity; Antioxidant property; Dithioacetals; Malononitrile; Sodium ethoxide

Indexed keywords

2 [BIS[(5 4 TOLYL 1,3,4 OXADIAZOL 2 YL)METHYLTHIO]METHYLENE]MALONONITRILE; 2 [BIS[(5 4 TOLYL 1,3,4 THIADIAZOL 2 YL)METHYLTHIO]METHYLENE]MALONONITRILE; 2 [BIS[(5 ARYL 1,3,4 OXADIAZOL 2 YL)METHYLTHIO]METHYLENE]MALONONITRILE DERIVATIVE; 2 [BIS[(5 ARYL 1,3,4 THIADIAZOL 2 YL)METHYLTHIO]METHYLENE]MALONONITRILE DERIVATIVE; 2 [BIS[(5 PHENYL 1,3,4 OXADIAZOL 2 YL)METHYLTHIO]METHYLENE]MALONONITRILE; 2 [BIS[(5 PHENYL 1,3,4 THIADIAZOL 2 YL)METHYLTHIO]METHYLENE]MALONONITRILE; 2 [BIS[[5 (4 CHLOROPHENYL) 1,3,4 OXADIAZOL 2 YL]METHYLTHIO]METHYLENE]MALONONITRILE; 2 [BIS[[5 (4 CHLOROPHENYL) 1,3,4 THIADIAZOL 2 YL]METHYLTHIO]METHYLENE]MALONONITRILE; 2 CYANO 3,3 BIS[(ETHOXYCARBONYL)METHYLTHIO]ACRYLNITRILE; 5 (4 CHLOROPHENYL) 2 (CHLOROMETHYL) 1,3,4 OXADIAZOLE; 5 (4 CHLOROPHENYL) 2 (CHLOROMETHYL) 1,3,4 THIADIAZOLE; 5 4 TOLYL 2 (CHLOROMETHYL) 1,3,4 OXADIAZOLE; 5 4 TOLYL 2 (CHLOROMETHYL) 1,3,4 THIADIAZOLE; 5 ARYL 2 (CHLOROMETHYL) 1,3,4 THIADIAZOLE DERIVATIVE; 5 PHENYL 2 (CHLOROMETHYL) 1,3,4 OXADIAZOLE; 5 PHENYL 2 (CHLOROMETHYL) 1,3,4 THIADIAZOLE; ANTIFUNGAL AGENT; ASCORBIC ACID; CHLORAMPHENICOL; ETHYL 3 AMINO 4 CYANO 5 [(ETHOXYCARBONYL)METHYLTHIO]THIOPHENE 2 CARBOXYLATE; KETOCONAZOLE; MALONONITRILE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DETERMINATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STAPHYLOCOCCUS AUREUS;

ANTI-INFECTIVE AGENTS; BACTERIA; BIPHENYL COMPOUNDS; FREE RADICAL SCAVENGERS; FUNGI; MICROBIAL SENSITIVITY TESTS; NITRILES; PICRATES;

EID: 79952283462     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.01.063     Document Type: Article

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