Synthesis of new series of 1-Aryl-1,4-dihydro-4-oxo-6-methyl pyridazine-3-carboxylic acid as potential antibacterial agents

European Journal of Medicinal Chemistry

Volumn 40, Issue 12, 2005, Pages 1325-1330

  Nagawade, Rahul R ^a   Khanna, Vijay V ^b   Bhagwat, Sachin S ^c   Shinde, Devanand B ^a  

^a DR BABASAHEB AMBEDKAR MARATHWADA UNIVERSITY   (India)

^b AHMEDNAGAR COLLEGE   (India)

^c BARKATULLAH UNIVERSITY   (India)

Author keywords

Antibacterial activity; Gram positive and Gram negative bacteria; Minimum inhibitory concentration ( g ml); Pharmacophore; Pyridazine 3 carboxylic acids; Quinolone antibiotic analogues

Indexed keywords

1 (2,4 DIFLUOROPHENYL) 1,4 DIHYDRO 4 OXO 6 METHYLPYRIDAZINE 3 CARBOXYLIC ACID; 1 (3 FLUOROPHENYL) 1,4 DIHYDRO 4 OXO 6 METHYLPYRIDAZINE 3 CARBOXYLIC ACID; 1 (3,4 DIFLUOROPHENYL) 1,4 DIHYDRO 4 OXO 6 METHYLPYRIDAZINE 3 CARBOXYLIC ACID; 1 (3,5 DIFLUOROPHENYL) 1,4 DIHYDRO 4 OXO 6 METHYLPYRIDAZINE 3 CARBOXYLIC ACID; 1 (4 CARBAMOYLPHENYL) 1,4 DIHYDRO 4 OXO 6 METHYLPYRIDAZINE 3 CARBOXYLIC ACID; 1 (4 CARBOXYPHENYL) 1,4 DIHYDRO 4 OXO 6 METHYLPYRIDAZINE 3 CARBOXYLIC ACID; 1 (4 CYANOPHENYL) 1,4 DIHYDRO 4 OXO 6 METHYLPYRIDAZINE 3 CARBOXYLIC ACID; 1 (4 FLUOROPHENYL) 1,4 DIHYDRO 4 OXO 6 METHYLPYRIDAZINE 3 CARBOXYLIC ACID; 1 (4 TRIFLUOROMETHYLPHENYL) 1,4 DIHYDRO 4 OXO 6 METHYLPYRIDAZINE 3 CARBOXYLIC ACID; ANTIINFECTIVE AGENT; CARBOXYLIC ACID DERIVATIVE; CIPROFLOXACIN; PYRIDAZINE DERIVATIVE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN; TROVAFLOXACIN; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; CARBOXYLIC ACIDS; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PYRIDAZINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 27744559331     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2005.05.012     Document Type: Article

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