Microfluidic bioassay to characterize parasitic nematode phenotype and anthelmintic resistance

Parasitology

Volumn 138, Issue 1, 2011, Pages 80-88

  Chen, Baozhen ^a   Deutmeyer, Alex ^a   Carr, John ^a   Robertson, Alan P ^b   Martin, Richard J ^b   Pandey, Santosh ^a  

^a Iowa State University   (United States)

^b IOWA STATE UNIVERSITY   (United States)

Author keywords

bioassay; levamisole resistance; microfluidics; Oesophagostomum dentatum; phenotype

Indexed keywords

LEVAMISOLE; ANTINEMATODAL AGENT;

ARTICLE; LOCOMOTION; MICROFLUIDIC ANALYSIS; NEMATODE; NONHUMAN; OESOPHAGOSTOMUM DENTATUM; OSCILLATION; PARASITE MIGRATION; PRIORITY JOURNAL; VELOCITY; ANIMAL; DRUG EFFECT; DRUG RESISTANCE; EVALUATION; HOST PARASITE INTERACTION; LARVA; METHODOLOGY; PARASITOLOGY; PHENOTYPE; PHYSIOLOGY; STRONGYLOIDEA; SWINE; SWINE DISEASE;

ANIMALIA; OESOPHAGOSTOMUM DENTATUM;

ANIMALS; ANTINEMATODAL AGENTS; DRUG RESISTANCE; HOST-PARASITE INTERACTIONS; LARVA; LEVAMISOLE; LOCOMOTION; MICROFLUIDIC ANALYTICAL TECHNIQUES; OESOPHAGOSTOMUM; PHENOTYPE; SWINE; SWINE DISEASES;

EID: 79952277616     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182010001010     Document Type: Article

References (33)

1. Albonico, M., Wright, V., Ramsan, M., Haji, H. J., Taylor, M., Savioli, L. and Bickle, Q. (2005). Development of the egg hatch assay for detection of anthelmintic resistance in human hookworms. International Journal for Parasitology 35, 803-811. (Pubitemid 40733619)
2. Chronis, N., Zimmer, M. and Bargmann, C. I. (2007). Microfluidics for in vivo imaging of neuronal and behavioral activity in Caenorhabditis elegans. Nature Methods 4, 727-731. (Pubitemid 47338167)
3. Cronin, C. J., Mendel, J. E., Mukhtar, S., Kim, Y. M., Stirbl, R. C., Bruck, J. and Sternberg, P.W. (2005). An automated system for measuring parameters of nematode sinusoidal movement. BMC Genetics 6, 1-6.
4. De Baere, S., Cherlet, M., Croubels, S., Baert, K. and De Backer, P. (2003). Liquid chromatographic determination of levamisole in animal plasma: Ultraviolet versus tandem mass spectrometric detection. Analytical Chimica Acta 483, 214-224.
5. Diawara, A., Drake, L. J., Suswillo, R. R., Kihara, J., Bundy, D. A. P., Scott, M. E., Halpenny, C., Stothart, J. R. and Pritchard, R. K. (2009). Assays to detect beta-tubulin codon 200 polymorphism in Trichuris trichiura and Ascaris lumbricoides. PLoS Neglected Tropical Diseases 3, e397.
6. Feng, Z., Cronin, C. J., Wittig, J. H., Sternberg, P.W. and Schafer, W. R. (2004). An imaging system for standardized quantitative analysis of C. elegans behavior. BMC Bioinformatics 5, 115.
7. Guest, M., Bull, K., Walker, R. J., Amliwala, K., O'Connor, V., Harder, A., Holden-dye, L. and Hopper, N. A. (2007). The calcium-activated channel, SLO-1, is required for the action of the novel cyclo-octadepsipeptide anthelmintic, emodepside, in Caenorhabditis elegans. International Journal for Parasitology 37, 1577-1588. (Pubitemid 47542465)
8. Gray, J. (1953). Undulatory propulsion. Quarterly Journal of Microscopical Science 94, 551-578.
9. Gray, J. and Lissmann, H.W. (1964). The locomotion of nematodes. Journal of Experimental Biology 41, 135-154.
10. Gray, J. M., Hill, J. J. and Bargmann, C. I. (2005). A circuit for navigation in Caenorhabditis elegans. Proceedings of the National Academy of Sciences, USA 102, 3184-3191. (Pubitemid 40328020)
11. Gray, J. M., Karow, D. S., Lu, H., Chang, A. J., Chang, J. S., Ellis, R. E., Marletta, M. A. and Bargmann, C. I. (2004). Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature, London 430, 317-322. (Pubitemid 38937733)
12. Heng, X., Erickson, D., Baugh, L. R., Yaqoob, Z., Sternberg, P.W., Psaltis, D. and Yang, C. (2006). Optofluidic microscopy-a method for implementing a high resolution optical microscope on a chip. Lab Chip 6, 1274-1276. (Pubitemid 44744291)
13. Hu, S., Ren, X., Bachman, M., Sims, C. E., Li, G. P. and Allbritton, N. (2002). Surface modification of poly (dimethylsiloxane) microfluidic devices by ultraviolet polymer grafting. Analytical Chemistry 74, 4117-4123. (Pubitemid 34912912)
14. Hulme, S. E., Shevkoplyas, S. S., Apfeld, J., Fontana, W. and Whitesides, G. M. (2007). A microfabricated array of clamps for immobilizing and imaging C. elegans. Lab Chip 7, 1515-1523. (Pubitemid 350013190)
15. Johnson, N. M., Behm, C. A. and Trowell, S. C. (2005). Heritable and inducible gene knockdown in C. elegans using Wormgate and the ORFeome. Gene 359, 26-34. (Pubitemid 41338708)
16. Kaplan, R. M. (2004). Drug resistance in nematodes of veterinary importance: A status report. Trends in Parasitology 20, 477-481. (Pubitemid 39195057)
17. Kerr, R., Lev-Ram, V., Baird, G., Vincent, P., Tsien, R. Y. and Schafer, W. R. (2000). Optical imaging of calcium transients in neurons and pharyngeal muscle of C. elegans. Neuron 26, 583-594.
18. Kotze, A. C., Clifford, S., O'Grady, J., Behnke, J. M. and McCarthy, J. S. (2004). An in vitro larval motility assay to determine anthelmintic sensitivity for human hookworm and Strongyloides species. American Journal of Tropical Medicine and Hygiene 71, 608-616. (Pubitemid 39601160)
19. Lockery, S. R., Lawton, K. J., Doll, J. C., Faumont, S. and Coulthard, S. M. (2008). Artificial dirt: Microfluidic substrates for nematode neurobiology and behavior. Journal of Neurophysiology 99, 3136-3143.
20. Martin, R. J. (1982). Electrophysiological effects of piperazine and diethylcarbamazine on Ascaris suum somatic muscle. British Journal of Pharmacology 77, 255-265. (Pubitemid 12032132)
21. Martin, R. J. (1997). Modes of action of anthelmintic drugs. Veterinary Journal 154, 11-34. (Pubitemid 27371230)
22. Martin, R. J., Bai, G., Clark, C. L. and Robertson, A. L. (2003). Methyridine (2-[2-methoxyethyl]-pyridine]) and levamisole activate different ACh receptor subtypes in nematode parasites: A new lead for levamisole-resistance. British Journal of Pharmacology 140, 1068-1076. (Pubitemid 37475973)
23. McNeal, R. (2002). Locomotion. The Biology of Nematodes (ed. Lee, D. L.), pp. 345-352. Taylor and Francis, London, UK. 345.
24. Nagel, G., Brauner, M., Liewald, J. F., Adeishvili, N., Bamberg, E. and Gottschalk, A. (2005). Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses. Current Biology 15, 2279-2284. (Pubitemid 41790623)
25. Pierce-Shimomura, J. T., Morse, T. M. and Lockery, S. R. (1999). The fundamental role of pirouettes in Caenorhabditis elegans chemotaxis. Journal of Neuroscience 19, 9557-9569. (Pubitemid 30228107)
26. Qin, J. and Wheeler, A. R. (2007). Maze exploration and learning in C. elegans. Lab Chip 7, 186-192. (Pubitemid 46238541)
27. Rohde, C. B., Zeng, F., Gonzalez-Rubio, R., Angel, M. and Yanik, M. F. (2007). Microfluidic system for on-chip high-throughput whole-animal sorting and screening at subcellular resolution. Proceedings of the National Academy of Sciences, USA 104, 13891-13895. (Pubitemid 350003307)
28. Ryu, W. S. and Samuel, A. D. (2002). Thermotaxis in Caenorhabditis elegans analyzed by measuring responses to defined thermal stimuli. Journal of Neuroscience 22, 5727-5733. (Pubitemid 35386495)
29. Sia, S. K. and Whitesides, G. M. (2003). Microfluidic devices fabricated in poly(dimethylsiloxane) for biological studies. Electrophoresis 24, 3563-3576. (Pubitemid 38089159)
30. Schwenkenbecher, J. M., Albonico, M., Bickle, Q. and Kaplan, R. M. (2007). Characterization of beta-tubulin genes in hookworms and investigation of resistance-associated mutations using real-time PCR. Molecular and Biochemical Parasitology 156, 167-174. (Pubitemid 47600369)
31. Whitesides, G. M. (2006). The origins and future of microfluidics. Nature, London 442, 368-373.
32. Wolstenholme, A. J. and Rogers, A. T. (2005). Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics. Parasitology 131, S85-S95.
33. Zhang, Y., Lu, H. and Bargmann, C. I. (2005). Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans. Nature, London 438, 179-184. (Pubitemid 41599864)