Cadherin-dependent adhesion of human U373MG glioblastoma cells promotes neurite outgrowth and increases migratory capacity: Laboratory investigation

Journal of Neurosurgery

Volumn 114, Issue 3, 2011, Pages 663-669

  Cifarelli, Christopher P ^a   Titus, Brian ^a   Yeoh, Hian Kwang ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Adhesion; Cadherin; Glioblastoma; Migration; Neurite; U373MG cell

Indexed keywords

BOVINE SERUM ALBUMIN; CADHERIN; COLLAGEN TYPE 4; IMMOBILIZED PROTEIN; VITRONECTIN;

ARTICLE; CADHERIN BASED ADHESION SYSTEM; CANCER INVASION; CELL ADHESION; CELL ASSAY; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME SUBSTRATE; GLIOBLASTOMA; HUMAN; HUMAN CELL; NERVE ELONGATION; NERVE FIBER GROWTH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; TUMOR CELL; TUMOR CELL CULTURE; TUMOR CELL LINE; TUMOR GROWTH; U373MG GLIOBLASTOMA CELL;

BRAIN NEOPLASMS; CADHERINS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELLS, IMMOBILIZED; EXTRACELLULAR MATRIX; GLIOBLASTOMA; HUMANS; NEOPLASM INVASIVENESS; NEURITES; RECOMBINANT PROTEINS;

EID: 79952273665     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2010.3.JNS091451     Document Type: Article

References (38)

1. Abramoff MD, Magelhaes PJ, Ram SJ: Image processing with ImageJ. Biophotonics Int 11:36-42, 2004
2. American Cancer Society: Cancer Facts & Figures 2008. (http://www.cancer.org/docroot/stt/content/stt-1x-cancer-facts-and-figures-2008. asp) [Accessed March 25, 2010]
3. Asano K, Duntsch CD, Zhou Q, Weimar JD, Bordelon D, Robertson JH, et al: Correlation of N-cadherin expression in high grade gliomas with tissue invasion. J Neurooncol 70:3-15, 2004 (Pubitemid 39193992)
4. Baumgart E, Cohen MS, Silva Neto B, Jacobs MA, Wotkowicz C, Rieger-Christ KM, et al: Identification and prognostic significance of an epithelial-mesenchymal transition expression profile in human bladder tumors. Clin Cancer Res 13:1685-1694, 2007 (Pubitemid 46952933)
5. Boggon TJ, Murray J, Chappuis-Flament S, Wong E, Gumbiner BM, Shapiro L: C-cadherin ectodomain structure and implications for cell adhesion mechanisms. Science 296:1308-1313, 2002 (Pubitemid 34522784)
6. Burden-Gulley SM, Payne HR, Lemmon V: Growth cones are actively influenced by substrate-bound adhesion molecules. J Neurosci 15:4370-4381, 1995
7. Central Brain Tumor Registry of the United States: CBTRUS Statistical Report: Primary Brain Tumors in the United States, 2000-2004. Central Brain Tumor Registry of the United States, 2008
8. Chappuis-Flament S, Wong E, Hicks LD, Kay CM, Gumbiner BM: Multiple cadherin extracellular repeats mediate homophilic binding and adhesion. J Cell Biol 154:231-243, 2001 (Pubitemid 34289291)
9. Couldwell WT, de Tribolet N, Antel JP, Gauthier T, Kuppner MC: Adhesion molecules and malignant gliomas: implications for tumorigenesis. J Neurosurg 76:782-791, 1992
10. de Groot J, Milano V: Improving the prognosis for patients with glioblastoma: the rationale for targeting Src. J Neurooncol 95:151-163, 2009
11. Gadducci A, Ferdeghini M, Cosio S, Annicchiarico C, Ciampi B, Bianchi R, et al: Preoperative serum E-cadherin assay in patients with ovarian carcinoma. Anticancer Res 19 (1B): 769-772, 1999 (Pubitemid 29168330)
12. Giese A, Bjerkvig R, Berens ME, Westphal M: Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol 21:1624-1636, 2003 (Pubitemid 46594118)
13. Giese A, Kucinski T, Knopp U, Goldbrunner R, Hamel W, Mehdorn HM, et al: Pattern of recurrence following local chemotherapy with biodegradable carmustine (BCNU) implants in patients with glioblastoma. J Neurooncol 66:351-360, 2004 (Pubitemid 38258351)
14. Hazan RB, Phillips GR, Qiao RF, Norton L, Aaronson SA: Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol 148:779-790, 2000
15. Hirohashi S: Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. Am J Pathol 153:333-339, 1998
16. Kashibuchi K, Tomita K, Schalken JA, Kume H, Takeuchi T, Kitamura T: The prognostic value of E-cadherin, alpha-, betaand gamma-catenin in bladder cancer patients who underwent radical cystectomy. Int J Urol 14:789-794, 2007 (Pubitemid 47313274)
17. Kleinman HK, Jacob K: Invasion assays. Curr Protoc Cell Biol Chapter 12:Unit 12.2, 2001
18. Lagenaur C, Lemmon V: An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension. Proc Natl Acad Sci U S A 84:7753-7757, 1987
19. Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, Ahkavan D, et al: Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Res 69:6889-6898, 2009
20. Maretzky T, Reiss K, Ludwig A, Buchholz J, Scholz F, Proksch E, et al: ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation. Proc Natl Acad Sci U S A 102:9182-9187, 2005 (Pubitemid 40923538)
21. Mohammadizadeh F, Ghasemibasir H, Rajabi P, Naimi A, Eftekhari A, Mesbah A: Correlation of E-cadherin expression and routine immunohistochemistry panel in breast invasive ductal carcinoma. Cancer Biomark 5:1-8, 2009
22. Nakada M, Anderson EM, Demuth T, Nakada S, Reavie LB, Drake KL, et al: The phosphorylation of ephrin-B2 ligand promotes glioma cell migration and invasion. Int J Cancer 126:1155-1165, 2010
23. Paradies NE, Grunwald GB: Purification and characterization of NCAD90, a soluble endogenous form of N-cadherin, which is generated by proteolysis during retinal development and retains adhesive and neurite-promoting function. J Neurosci Res 36:33-45, 1993 (Pubitemid 23260460)
24. Perego C, Vanoni C, Massari S, Raimondi A, Pola S, Cattaneo MG, et al: Invasive behaviour of glioblastoma cell lines is associated with altered organisation of the cadherin-catenin adhesion system. J Cell Sci 115:3331-3340, 2002 (Pubitemid 34960185)
25. Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G: A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392:190-193, 1998 (Pubitemid 28162793)
26. Reiss K, Maretzky T, Ludwig A, Tousseyn T, de Strooper B, Hartmann D, et al: ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling. EMBO J 24:742-752, 2005 (Pubitemid 40396104)
27. Riehl R, Johnson K, Bradley R, Grunwald GB, Cornel E, Lilienbaum A, et al: Cadherin function is required for axon outgrowth in retinal ganglion cells in vivo. Neuron 17:837-848, 1996 (Pubitemid 26424012)
28. Rønn LC, Ralets I, Hartz BP, Bech M, Berezin A, Berezin V, et al: A simple procedure for quantification of neurite outgrowth based on stereological principles. J Neurosci Methods 100:25-32, 2000
29. Shapiro L, Love J, Colman DR: Adhesion molecules in the nervous system: structural insights into function and diversity. Annu Rev Neurosci 30:451-474, 2007 (Pubitemid 47218764)
30. Shinoura N, Paradies NE, Warnick RE, Chen H, Larson JJ, Tew JJ, et al: Expression of N-cadherin and alpha-catenin in astrocytomas and glioblastomas. Br J Cancer 72:627-633, 1995
31. Stupp R, Hegi ME, Gilbert MR, Chakravarti A: Chemoradiotherapy in malignant glioma: standard of care and future directions. J Clin Oncol 25:4127-4136, 2007 (Pubitemid 47492957)
32. Stupp R, Hegi ME, van den Bent MJ, Mason WP, Weller M, Mirimanoff RO, et al: Changing paradigms - an update on the multidisciplinary management of malignant glioma. Oncologist 11:165-180, 2006 (Pubitemid 43261763)
33. Takeichi M: The cadherin superfamily in neuronal connections and interactions. Nat Rev Neurosci 8:11-20, 2007
34. Tysnes BB, Mahesparan R: Biological mechanisms of glioma invasion and potential therapeutic targets. J Neurooncol 53:129-147, 2001 (Pubitemid 33036822)
35. Uemura K, Kihara T, Kuzuya A, Okawa K, Nishimoto T, Ninomiya H, et al: Characterization of sequential N-cadherin cleavage by ADAM10 and PS1. Neurosci Lett 402:278-283, 2006 (Pubitemid 43850164)
36. Wang LF, Fokas E, Juricko J, You A, Rose F, Pagenstecher A, et al: Increased expression of EphA7 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients. BMC Cancer 8:79, 2008
37. Wanner IB, Guerra NK, Mahoney J, Kumar A, Wood PM, Mirsky R, et al: Role of N-cadherin in Schwann cell precursors of growing nerves. Glia 54:439-459, 2006 (Pubitemid 44422944)
38. Wanner IB, Wood PM: N-cadherin mediates axon-aligned process growth and cell-cell interaction in rat Schwann cells. J Neurosci 22:4066-4079, 2002 (Pubitemid 37465715)