Viruses and breast cancer

Cancers

Volumn 2, Issue 2, 2010, Pages 752-772

  Lawson, James S ^a   Heng, Benjamin ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Bovine leukemia virus; Breast cancer; Epstein barr virus; Etiology; Human papilloma virus; Mouse mammary tumor virus; Viruses

Indexed keywords

TAMOXIFEN; TRASTUZUMAB;

BOVINE LEUKEMIA VIRUS; BREAST CANCER; BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER INCIDENCE; CANCER INHIBITION; CANCER MORTALITY; CAUSAL ATTRIBUTION; CYTOMEGALOVIRUS; EPSTEIN BARR VIRUS; FOOD INTAKE; HUMAN; INTRADUCTAL CARCINOMA; MIGRATION; MOUSE MAMMARY TUMOR ONCOVIRUS; REVIEW; RISK FACTOR; SIMIAN VIRUS 40; UTERINE CERVIX CANCER; VIRUS CARCINOGENESIS; VIRUS TRANSMISSION; WART VIRUS;

EID: 79952259307     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers2020752     Document Type: Review

References (92)

1. Kolata, G. Grant system leads cancer researchers to play it safe. New York Times, June 27, 2009. Available online at: http://www.nytimes.com/2009/06/28/health/research/28cancer.html?_r=1 (accessed on 30 April 2010, based on data from the US National Cancer Institute).
2. Lawson, J.S.; Guenzburg, W.; Whitaker. N.J. Viruses and breast cancer. Future Microb. 2006, 1, 33-51.
3. Veronesi, U.; Goldhirsch, A.; Orecchia, R.; Vlale, G.; Boyle, P. Breast cancer. Lancet 2005, 365, 1727-1741.
4. van de Vijver, M.J.; He, Y.D.; van't Veer, L.J.; Dai, H.; Hart, A.A.; Voskuil, D.W.; Schreiber, G.J.; Peterse, J.L.; Roberts, C.; Marton, M.J.; Parrish, M.; Atsma, D.; Witteveen, A.; Glas, A.; Delahaye, L.; van der Velde, T.; Bartelink, H.; Rodenhuis, S.; Rutgers, E.T.; Friend, S.H.; Bernards, R. A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med. 2002, 347, 1999-2009.
5. Land, C.E.; McGregor, D.H. Breast cancer incidence among atomic bomb survivors: implications for radiobiologic risk at low doses. J. Natl. Cancer Inst. 1979, 62, 17-21.
6. Yager, J.D.; Davidson, N.E. Estrogen carcinogenesis in breast cancer. N. Engl. J. Med. 2006, 354, 270-282.
7. Marshall, S.F.; Clarke, C.A.; Deapen, D.; Henderson, K.D.; Largent, J.; Neuhausen, S.L.; Reynolds, P.; Ursin, G.; Horn-Ross, P.L.; Stram, D.O.; Templeman, C.; Bernstein, L. Recent breast cancer incidence trends according to hormone therapy use: the California Teachers Study cohort. Breast Cancer Res. 2010, 12, R4; doi:10.1186/bcr2467.
8. Stanford, J.L.; Herrington, L.J.; Schwartz, S.M.; Weiss, N.S. Breast cancer incidence in Asian migrants to the US and their descendants. Epidemiology 1995, 6, 181-183.
9. Smith-Warner, S.A.; Spiegelman, D.; Adami, H.O.; Beeson, W.L.; van den Brandt, P.A.; Folsom, A.R.; Fraser, G.E.; Freudenheim, J.L.; Goldbohm, R.A.; Graham, S.; Kushi, L.H.; Miller, A.B.; Rohan, T.E.; Speizer, F.E.; Toniolo, P.; Willett, W.C.; Wolk, A.; Zeleniuch-Jacquotte, A.; Hunter, D.J. Types of dietary fat and breast cancer: a pooled analysis of cohort studies. Int. J. Cancer 2001, 92, 767-774.
10. Wakai, K.; Dillon, D.S.; Ohno, Y.; Prihartono, J.; Budiningsih, S.; Ramli, M.; Darwis, I.; Tjindarbumi, D.; Tjahjadi, G.; Soetrisno, E.; Roostini, E.S.; Sakamoto, G.; Herman, S.; Cornain, S. Fat intake and breast cancer risk in an area where fat intake is low: a case control study in Indonesia. Int. J. Epidemiol. 2000, 29, 20-28.
11. Goldin, B.R.; Adlercreutz, H.; Gorbach, S.L.; Woods, M.N.; Dwyer, J.T.; Conlon, T.; Bohn, E.; Gershoff, S.N. The relationship between estrogen levels and diets of Caucasian American and Oriental immigrant women. Am. J. Clin. Nutr. 1986, 44, 945-953.
12. Anderson, A.S.; Bush, H.; Lean, M.; Bradby, H.; Williams, R.; Lea, E. Evolution of atherogenic diets in South Asian and Italian women after migration to a higher risk region. J. Hum. Nutr. Diet.2005, 18, 33-43.
13. International Agency for Research on Cancer. CancerMondial. Globocan 2002 database (2005) Available online at: http://www-dep.iarc.fr (accessed on 1 March 2010)
14. Apparent Food Consumption per Capita as Calories and Total Fats for Year 2002; Food and Agriculture Organization: Rome, Italy, 2005.
15. Yasui, Y.; Potter, J.D.; Stanford, J.L.; Rossing, M.A.; Winget, M.D.; Bronner, M.; Daling, J. Breast cancer risk and "delayed" primary Epstein-Barr virus infection. Cancer Epidemiol. Biomarkers Prev. 2001, 10, 9-16.
16. Stewart, T.H.; Sage, R.D.; Stewart, A.F.; Cameron, D.W. Breast cancer incidence highest in the range of one species of house mouse, Mus domesticus. Br. J. Cancer 2000, 82, 446-451.
17. Weigelt, B.; Reis-Filho, J.S. Histological and molecular types of breast cancer: is there a unifying taxonomy? Nat. Rev. Clin. Oncol. 2009, 6, 718-730.
18. Lawson, J.S.; Glenn, W.K.; Heng, B.; Ye, Y.; Tran, B.; Lutze-Mann, L.; Whitaker, N.J. Koilocytes indicate a role for human papilloma virus in breast cancer. Br. J. Cancer 2009, 101, 1351-1356.
19. Lawson, J.S.; Glenn, W.K.; Salmons, B.; Ye, Y.; Heng, B.; Moody, P.; Johal, H.; Rawlinson, W.D.; Delprado, W.; Lutze-Mann, L.; Whitaker, N.J. Mouse mammary tumor virus-like sequences in human breast cancer. Cancer Res. 2010, doi 10.1158/0008-5472.
20. Lawson, J.S.; Field, A.S.; Champion, S.; Tran, D.; Ishikura, H.; Trichopoulos, D. Low oestrogen receptor alpha expression in normal breast tissue underlies low breast cancer incidence in Japan. Lancet 1999, 354, 1787-1788.
21. Lawson, J.S.; Field, A.S.; Tran, D.D.; Killeen, J.; Maskarenic, G.; Ishikura, H.; Trichopoulos, D. Breast cancer incidence and oestrogen receptors in normal mammary tissue. An epidemiological study among Japanese women in Japan and Hawaii. Int. J. Cancer 2002, 97, 685-687.
22. Lawson, J.S.; Field, A.S.; Tran, D.D.; Houssami, N. Hormone replacement therapy use dramatically increases breast oestrogen receptor expression in obese postmenopausal women. Breast Cancer Res. 2001, 3, 342-345.
23. Russo, J.; Ao, X.; Grill, C.; Russo, I.H. Pattern of distribution of cells positive for estrogen receptor alpha and progesterone receptor in relation to proliferating cells in the mammary gland. Breast Cancer Res. Treat. 1999, 53, 217-227.
24. Khan, S.A.; Rogers, M.A.; Khurana, K.; Meguid, M.M.; Numann, P.J. Estrogen receptor expression in benign breast epithelium and breast cancer risk. J. Natl. Cancer Inst. 1998, 90, 37-42.
25. Liehr, J.G. Genotoxicity of the steroidal oestrogens oestrone and oestradiol: possible mechanism of uterine and mammary cancer development. Hum. Reprod. Update 2001, 7, 272-281.
26. Greendale, G.A.; Reboussin, B.A.; Sie, A.; Singh, H.R.; Olson, L.K.; Gatewood, O.; Bassett, L.W.; Wasilauskas, C.; Bush, T.; Barrett-Connor, E. Effect of estrogen and estrogen-progestin on mammographic parenchymal density. Postmenopausal Estrogen/Progestin Interventions (PEPI) Investigators. Ann. Intern. Med. 1999, 130, 262-269.
27. Bittner, J.J. Some possible effects of nursing on the mammary gland tumor incidence in mice. Science 1936, 84, 162.
28. Di Lonardo, A.; Venuti, A.; Marcante, M.L. Human papillomavirus in breast cancer. Breast Cancer Res. Treat. 1992, 21, 95-100.
29. Horiuchi, K.; Mishima, K.; Ohsawa, M.; Aozasa, K. Carcinoma of stomach and breast with lymphoid stroma: localisation of Epstein-Barr virus. J. Clin. Pathol. 1994, 47, 538-540.
30. Wang, Y.; Holland, J.F.; Bleiweiss, I.J.; Melana, S.; Liu, X.; Pelisson, I.; Cantarella, A.; Stellrecht, K.; Mani, S.; Pogo, B.G. Detection of mammary tumor virus env gene-like sequences in human breast cancer. Cancer Res. 1995, 55, 5173-5179.
31. Indraccolo, S.; Günzburg, W.H.; Leib-Mösch, C.; Erfle, V.;Salmons, B. Identification of three human sequences with viral superantigen-specific primers. Mamm. Genome 1995, 6, 339-344.
32. Buehring, G.C.; Kramme, P.K.; Schultz, R.D. Evidence for bovine leukemia virus in the mammary epithelial cells of infected cows. Lab. Invest. 1994, 71, 359-365.
33. Buehring, G.C.; Philpott, S.M.; Choi, K.Y. Humans have antibodies reactive with Bovine leukemia virus. AIDS Res. Hum. Retrovir. 2003, 19, 1105-1113.
34. Buehring, G.C.; Shen, H.M.; Jensen, H.M.; Block, G. Bovine leukemia virus infection is significantly associated with risk of breast cancer. Proc. Amer. Assoc. Cancer Res. 2007, 48, 1747.
35. Amarante, K.A.; Watanabe, M.A.E. The possible involvement of virus in breast cancer. J. Cancer Res. Clin. Oncol. 2009, 135, 329-337.
36. Heng, B.; Glenn, W.K.; Ye, Y.; Tran, D.; Delprado, W.; Lutze-Mann, L.; Whitaker, N.J.; Lawson, J.S. Human papilloma virus is associated with breast cancer. Br. J. Cancer 2009, 101, 1345-1350.
37. Gumus, M.; Yumuk, P.F.; Salepci, T.; Aliustaoglu, M.; Dane, F.; Ekenel, M.; Basaran, G.; Kaya, H.; Barisik, N.; Turhal, N.S. HPV DNA frequency and subset analysis in human breast cancer patients' normal and tumoral tissue samples. J. Exp. Clin. Cancer Res. 2006, 25, 515-521.
38. Hennig, E.M.; Suo, Z.; Thoresen, S.; Holm, R.; Kvinnsland, S.; Nesland, J.M. Human papillomavirus 16 in breast cancer of women treated for high grade cervical intraepithelial neoplasia (CIN III). Breast Cancer Res. Treat. 1999, 53, 121-135.
39. Widschwendter, A.; Brunhuber, T.; Wiedemair, A.; Mueller-Holzner, E.; Marth, C. Detection of human papillomavirus DNA in breast cancer of patients with cervical cancer history. J. Clin. Virol. 2004, 31, 292-297.
40. Khan, N.A.; Castillo, A.; Koriyama, C.; Kijima, Y.; Umekita, Y.; Ohi, Y.; Higashi, M.; Sagara, Y.; Yoshinaka, H.; Tsuji, T.; Natsugoe, S.; Douchi, T.; Eizuru, Y.; Akiba, S. Human papillomavirus detected in female breast carcinomas in Japan. Br. J. Cancer 2008, 99, 408-414.
41. Thomison, J.; Thomas, L.K.; Shroyer, K.R. Human papillomavirus: molecular and cytologic/histologic aspects related to cervical intraepithelial neoplasia and carcinoma. Hum. Pathol. 2008, 39, 154-166.
42. Webster, K.; Taylor, A.; Gaston, K. Oestrogen and progesterone increase the levels of apoptosis induced by the human papillomavirus type 16 E2 and E7 proteins. J. Gen. Virol. 2001, 82, 201-213.
43. Khan, M.A.; Canhoto, A.J.; Housley, P.R.; Creek, K.E.; Pirisi, L. Glucocorticoids stimulate growth of human papillomavirus type 16 (HPV16)-immortalized human keratinocytes and support HPV16-mediated immortalization without affecting the levels of HPV16 E6/E7 mRNA. Exp. Cell Res. 1997, 236, 304-310.
44. Dimri, G.; Band, H.; Band, V. Mammary epithelial cell transformation: insights from cell culture and mouse models. Breast Cancer Res. 2005, 7, 171-179.
45. Strickler, H.D.; Schiffman, M.H.; Shah, K.V.; Rabkin, C.S.; Schiller, J.T., Wacholder S.; Clayman, B.; Viscidi, R.P. A survey of human papillomavirus 16 antibodies in patients with epithelial cancers. Eur. J. Cancer Prev. 1998, 305-313.
46. Bryan, J.T.; Brown, D.R. Transmission of human papillomavirus type 11 infection by desquamated cornified cells. Virology 2001, 281, 35-42.
47. Pao, C.C.; Lin, S.S.; Lin, C.Y.; Maa, J.S.; Lai, C.H.; Hsieh, T.T. Identification of human papillomavirus DNA sequences in peripheral blood mononuclear cells. Am. J. Clin. Pathol. 1991, 95, 540-546.
48. Chen, A.C.; Keleher, A.; Kedda, M.A.; Spurdle, A.B.; McMillan, N.A.; Antonsson, A. Human papillomavirus DNA detected in peripheral blood samples from healthy Australian male blood donors. J. Med. Virol. 2009, 81, 1792-1796.
49. D'Souza, G.; Agrawal, Y.; Halpern, J.; Bodison, S.; Gillison, M.L. Oral sexual behaviors associated with prevalent oral human papillomavirus infection. J. Infect. Dis. 2009, 199, 1263-1269.
50. Rintala, M.A.; Grénman, S.E.; Järvenkylä, M.E.; Syrjänen, K.J.; Syrjänen, S.M. High-risk types of human papillomavirus (HPV) DNA in oral and genital mucosa of infants during their first 3 years of life: experience from the Finnish HPV Family Study. Clin. Infect. Dis. 2005, 41, 1728-1733.
51. Salmons, B.; Gunzburg, W.H. Current perspectives in the biology of mouse mammary tumor virus. Virus Res. 1987, 8, 81-102.
52. Teo, I.A.; Shaunak, S. Polymerase chain reaction in situ: an appraisal of an emerging technique. Histochem. J. 1995, 27, 647-659.
53. Ford, C.E., Faedo, M., Rawlinson, W.D. Mouse mammary tumor virus-like RNA transcripts and DNA are found in affected cells of human breast cancer. Clin. Cancer Res. 2004, 10, 7284-7289.
54. Melana, S.M.; Nepomnaschy, I.; Sakalian, M.; Abbott, A.; Hasa, J.; Holland, J.F., Pogo, B.G. Characterization of viral particles isolated from primary cultures of human breast cancer cells. Cancer Res. 2007, 67, 8960-8965.
55. Etkind, P.R.; Stewart, A.F.; Wiernik, P.H. Mouse mammary tumor virus (MMTV)-like DNA sequences in the breast tumors of father, mother, and daughter. Infect. Agent Cancer 2008, 3, 2, doi: 10.1186/1750-9378-3-2.
56. Indik, S.; Günzburg, W.H.; Salmons, B.; Rouault, F. Mouse mammary tumor virus infects human cells. Cancer Res. 2005, 65, 6651-6659.
57. Indik, S.; Günzburg, W.H.; Kulich, P.; Salmons, B.; Rouault, F. Rapid spread of mouse mammary tumor virus in cultured human breast cells. Retrovirology 2007, 4, 73-88.
58. Faschinger, A.; Rouault, F.; Sollner, J.; Lukas, A.; Salmons, B.; Gunzburg, W.H.; Indik, S. Mouse mammary tumor virus integration site selection in human and mouse genomes. J. Virol. 2008, 82, 1360-1367.
59. Callahan, R.; Smith, G.H. MMTV-induced mammary tumorigenesis: gene discovery, progression to malignancy and cellular pathways. Oncogene 2000, 19, 992-1001.
60. Highman, B.; Norvell, M.J.; Shellenberger, T.E. Pathological changes in female C3H mice continuously fed diets containing diethylstilboestrol or 17-estradiol. J. Environ. Pathol. Toxicol.1978, 1, 1-30
61. Svec, J.; Links, J. MMTV production stimulated by hormones and polyamines in cells grown in semi-synthetic in vitro conditions. Int. J. Cancer 1977, 19, 249-257.
62. Peters, G.; Lee, A.E.; Dickson, C. Activation of cellular gene by mouse mammary tumour virus may occur early in mammary tumour development. Nature 1984, 309, 273-275.
63. Wang, Y.; Melana, S.M.; Baker, B.; Bleiweiss, I.; Fernandez-Cobo, M.; Mandeli, J.F.; Holland, J.F.; Pogo, B.G.T. High prevalence of MMTV-like env gene sequences in gestational breast cancer. Med. Oncol. 2003, 20, 233-236.
64. Lushnikova, A.A.; Kryukova, I.N.; Rotin, D,L.; Lubchenko, L.N. Detection of the env MMTVhomologous sequences in mammary carcinoma patient intestine lymphoid tissue. Dokl. Biol. Sci.2004, 39, 9423-9426.
65. Ford, C.E. Mouse mammary tumor virus and breast cancer. Ph.D. Thesis, University of New South Wales, 2004.
66. Johal, H. Mouse mammary tumor virus identified in human milk. Personal communication. 2010.
67. Wang, Y.; Jiang, J.D.; Xu, D.; Li, Y.; Qu. C.; Holland, J.F.; Pogo, B.G. A mouse mammary tumor virus-like long terminal repeat superantigen in human breast cancer. Cancer Res. 2004, 64, 4105-4111.
68. Katz, E.; Lareef, M.H.; Rassa, J.C.; Grande, S.M.; King, L.B.; Russo, J.; Ross, S.R.; Monroe, J.G. MMTV Env encodes an ITAM responsible for transformation of mammary epithelial cells in three-dimensional culture. J. Exper. Med. 2005, 201, 431-439.
69. Ross, S.R.; Schmidt, J.W.; Katz. E.; Cappelli, L.; Hultine, S.; Gimotty, P.; Monroe, J.G. Animmunoreceptor tyrosine activation motif in the mouse mammary tumor virus envelope protein plays a role in virus-induced mammary tumors. J. Virol. 2006, 80, 9000-9008.
70. Beral, V.; Bull, D.; Doll, D.; Peto, R.; Reeves, G. Breast cancer and breastfeeding: collaborative reanalysis of individual data from 47 epidemiological studies in 30 countries, including 50 302 women with breast cancer and 96 973 women without the disease. Lancet 2002, 360, 187-195.
71. Lawson, J.S.; Heads, J.; Glenn, W.K.; Whitaker, N.J. Breastfeeding, breast milk and viruses. BMC Women's Health 2007, 7, 17-20.
72. Moore, D.H.; Long, C.A.; Vaidya, A.A.; Sheffield, J.B.; Dion, A.S.; Lasfargues, E.Y. Mammary tumor viruses. Adv. Cancer Res. 1979, 29, 347-414.
73. Coovadia HM, Rollins NC, Bland RM, Little K, Coutsoudis A, Bennish ML, Newell M-L: Mother-to-child transmission of HIV-1 infection during exclusive breastfeeding in the first 6 months of life: an intervention cohort study. Lancet 2007, 369, 1107-1116.
74. Dendy, D.A.V.; Dobraszczyk, B.J. Infestation by invertebrates. In Cereals and Cereal Products; Aspen: Gaithersburg, MD, USA, 2001; p. 40.
75. th ed.; Arnold: London, UK, 1998.
76. Tyan, Y.S.; Liu, S.T.; Ong, W.R.; Chen, M.L.; Shu, C.H.; Chang, Y.S. Detection of Epstein-Barr virus and human papillomavirus in head and neck tumors. J. Clin. Microbiol. 1993, 31, 53-56.
77. Rassekh, C.H.; Rady, P.L.; Arany, I.; Tyring, S.K.; Knudsen, S.; Calhoun, K.H.; Seikaly, H.; Bailey, B.J. Combined Epstein-Barr virus and human papillomavirus infection in nasopharyngeal carcinoma. Laryngoscope 1998, 108, 362-367.
78. Mirzamani, N.; Salehian, P.; Farhadi, M.; Tehran, E.A. Detection of EBV and HPV in nasopharyngeal carcinoma by in situ hybridization. Exp. Mol. Pathol. 2006, 81, 231-234
79. Kalkan, A.; Ozdarendeli, A.; Bulut, Y.; Yekeler, H.; Cobanoglu, B.; Doymaz, M.Z. Investigation of Epstein-Barr virus DNA in formalin-fixed and paraffin- embedded breast cancer tissues. Med. Princ. Pract. 2005, 14, 268-271
80. Fina, F.; Romain, S.; Ouafik, L.; Palmari, J.; Ben Ayed, F.; Benharkat, S., Bonnier, P.; Spyratos, F.; Foekens, J.A.; Rose, C.; Buisson, M.; Gérard, H.; Reymond, M.O.; Seigneurin, J.M.; Martin, P.M. Frequency and genome load of Epstein-Barr virus in 509 breast cancers from different geographical areas. Br. J. Cancer 2002, 84, 783-790.
81. Bonnet, M.; Guinebretiere, J.M.; Kremmer, E.; Grunewald, V.; Benhamou, E.; Contesso, G.; Joab, I. Detection of Epstein-Barr virus in invasive breast cancer. J. Natl. Cancer Inst. 1999, 91, 1376-1381.
82. Hennard, C.; Pfuhl, C.; Buettner, M.; Becker, K-F.; Knofel, T.; Middeldorp, J.; Kremmer, E.; Niedobitek, G.; Grasser, F.A. The antibody 2B4 directed against the Epstein-Barr virus (EBV)- encoded nuclear antigen 1 (EBNA1) detects MAGE-4: implications for studies on the EBV association of human cancers. J. Pathol. 2006, 209, 430-435.
83. Junker, A.K.; Thomas, E.E.; Radcliffe, A.; Forsyth, R.B.; Davidson, A.G.F.; Rymao, L. Epstein- Barr virus shedding in breast milk. Am. J. Med. Sci. 1991, 302, 220-223.
84. Xue, S.A.; Lampert, I.A.; Haldane, J.S.; Bridger, J.E.; Griffin, B.E. Epstein-Barr virus gene expression in human breast cancer: protagonist or passenger. Br. J. Cancer 2003, 89, 113-119.
85. Speck, P.; Longnecker, R. Infection of breast epithelial cells with Epstein-Barr virus via cell-tocell contact. J. Nat. Cancer Inst. 2000, 92, 1849-1851.
86. Schneider, F.; Neugebauer, J.; Griese, J.; Liefold, N.; Kutz, H.; Briseño, C.; Kieser, A. The viral oncoprotein LMP1 exploits TRADD for signaling by masking its apoptotic activity. PLoS Biol.2008, 6, e8
87. Wei, M.X.; Turenne-Tessier, M.; Decaussin, G.; Benet, G.; Ooka, T. Establishment of a monkey kidney epithelial cell line with the BARF1 open reading frame from Epstein-Barr virus. Oncogene 1997, 14, 3073-3081.
88. Nishikawa, J.; Imai, S.; Oda, T.; Kojima, T.; Okita, K.; Takada, K. Epstein-Barr virus promotes epithelial cell growth in the absence of EBNA2 and LMP1 expression. J. Virol. 1999, 73, 1286-1292.
89. Küppers, R.; Hansmann, M.L. The Hodgkin and Reed/Sternberg cell. Int. J. Biochem. Cell Biol.2005, 37, 511-517.
90. Strum, S.B.; Park, J.K.; Rappaport, H. Observation of cells resembling Sternberg-Reed cells in conditions other than Hodgkin's disease. Cancer 1970, 26, 176-190.
91. Brooks, S.A.; Leathem, A.J. Expression of the CD15 antigen (Lewis x) in breast cancer. Histochem. J. 1995, 27, 689-693.
92. Lawson, J,S.; Tran, D.D.; Carpenter, E.; Ford, C.E.; Rawlinson, W.D.; Whitaker, N.J.; Delprado, W. Presence of mouse mammary tumor-like virus gene sequences may be associated with specific human breast cancer morphology. J. Clin. Pathol. 2006, 59, 1287-1292.