Crystal structure of the dynein motor domain

Science

Volumn 331, Issue 6021, 2011, Pages 1159-1165

  Carter, Andrew P ^a,b   Cho, Carol ^a   Jin, Lan ^a   Vale, Ronald D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; DIMER; DYNEIN ADENOSINE TRIPHOSPHATASE; PROTEIN INTERACTING WITH PROTEIN KINASE C;

CRYSTAL STRUCTURE; CYTOLOGY; CYTOPLASM; ENZYME ACTIVITY; MOLECULAR ANALYSIS; PROTEIN;

ARTICLE; COILED BODY; CRYSTAL STRUCTURE; MICROTUBULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; YEAST;

ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYTOPLASMIC DYNEINS; METHIONINE; MICROTUBULES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 79952254224     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1202393     Document Type: Article

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40. We thank N. Zhang (UCSF), J. Holton (Advanced Light Source), H. Schmidt (MRC), E. Gleave (MRC), and M. Sirajuddin (UCSF) for their assistance and helpful discussions. This work was supported by the NIH (R.D.V.), Jane Coffin Child Foundation (A.P.C.), Lymphoma and Leukemia Foundation (A.P.C.), American Heart Association (C.C.), and Genentech Graduate Student Fellowship (C.C.). The PDB accession number for this dynein dimer structure is 3QMZ.