Validated LC-MS/MS method for the determination of maackiain and its sulfate and glucuronide in blood: Application to pharmacokinetic and disposition studies

Journal of Pharmaceutical and Biomedical Analysis

Volumn 55, Issue 2, 2011, Pages 288-293

  Gao, Song ^a   Yang, Zhen ^a   Yin, Taijun ^a   You, Ming ^b   Hu, Ming ^a  

^a UNIVERSITY OF HOUSTON   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Maackiain; Maackiain 7 glucuronide; Maackiain 7 sulfate; Pharmacokinetics; UPLC MS MS

Indexed keywords

ACETONITRILE; FLAVONOID; MAACKIAIN; MAACKIAIN 7 GLUCURONIDE; MAACKIAIN 7 SULFATE; METHANOL; UNCLASSIFIED DRUG; WATER;

ACCURACY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG DETERMINATION; DRUG DISPOSITION; DRUG EXCRETION; DRUG GLUCURONIDATION; DRUG METABOLISM; DRUG PENETRATION; DRUG STRUCTURE; DRUG SULFATION; DRUG TRANSPORT; ELECTROSPRAY MASS SPECTROMETRY; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; VALIDATION PROCESS;

ANIMALS; CACO-2 CELLS; CALIBRATION; CHROMATOGRAPHY, LIQUID; GLUCURONIDES; HUMANS; MALE; MICE; PTEROCARPANS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 79952249980     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2011.01.015     Document Type: Article

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