Influence of a locomotor training approach on walking speed and distance in people with chronic spinal cord injury: A randomized clinical trial

Physical Therapy

Volumn 91, Issue 1, 2011, Pages 48-60

  Field Fote, Edelle C ^a   Roach, Kathryn E ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CHRONIC DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CONVALESCENCE; EXERCISE TEST; FEMALE; FOLLOW UP; HOSPITALIZATION; HUMAN; KINESIOTHERAPY; MALE; METHODOLOGY; MIDDLE AGED; MOTOR DYSFUNCTION; NONPARAMETRIC TEST; PHYSIOTHERAPY; RANDOMIZED CONTROLLED TRIAL; ROBOTICS; SINGLE BLIND PROCEDURE; SPINAL CORD INJURY; TREATMENT OUTCOME; WALKING; WEIGHT BEARING;

ADULT; CHRONIC DISEASE; EXERCISE TEST; EXERCISE THERAPY; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MOVEMENT DISORDERS; PHYSICAL THERAPY MODALITIES; RECOVERY OF FUNCTION; ROBOTICS; SEVERITY OF ILLNESS INDEX; SINGLE-BLIND METHOD; SPINAL CORD INJURIES; STATISTICS, NONPARAMETRIC; TREATMENT OUTCOME; WALKING; WEIGHT-BEARING; YOUNG ADULT;

EID: 79952236229     PISSN: 00319023     EISSN: 15386724     Source Type: Journal    
DOI: 10.2522/ptj.20090359     Document Type: Article

References (46)

1. National Spinal Cord Injury Information Network. Spinal cord injury facts and figures at a glance. National Spinal Cord Injury Statistical Center. Available at: https://www.nscisc.uab.edu/public-content/pdf/FactsApr09.pdf. Published April 2009. Accessed September 16, 2010.
2. Tator CH, Duncan EG, Edmonds VE, et al. Changes in epidemiology of acute spinal cord injury from 1947 to 1981. Surg Neurol. 1993;40:207-215. (Pubitemid 23237535)
3. Barbeau H, Blunt R. A novel interactive locomotor approach using body weight support to retrain gait in spastic paretic subjects. In: Wernig A, ed. Plasticity of Motoneuronal Connections. Amsterdam, the Netherlands: Elsevier Science Publishers; 1991:461-474.
4. Bouyer LJ. Animal models for studying potential training strategies in persons with spinal cord injury. J Neurol Phys Ther. 2005;29:117-125.
5. Hiebert GW, Whelan PJ, Prochazka A, Pearson KG. Contribution of hind limb flexor muscle afferents to the timing of phase transitions in the cat step cycle. J Neurophysiol. 1996;75:1126-1137. (Pubitemid 26087479)
6. Emken JL, Benitez R, Reinkensmeyer DJ. Human-robot cooperative movement training: learning a novel sensory motor transformation during walking with robotic assistance-as-needed. J Neuroeng Rehabil. 2007; 4:8.
7. Cai LL, Fong AJ, Otoshi CK, et al. Implications of assist-as-needed robotic step training after a complete spinal cord injury on intrinsic strategies of motor learning. J Neurosci. 2006;26:10564-10568. (Pubitemid 44564608)
8. Wolpert DM, Miall RC. Forward models for physiological motor control. Neural Netw. 1996;9:1265-1279. (Pubitemid 26413051)
9. Field-Fote E, Tepavac D. Combined use of body weight support, functional electric stimulation, and treadmill training to improve walking ability in individuals with chronic incomplete spinal cord injury. Arch Phys Med Rehabil. 2001;82:818-824. (Pubitemid 32520794)
10. Bussel B. Late flexion reflex in paraplegic patients: evidence for a spinal stepping generator. Brain Res Bull. 1989;22:53-56.
11. Bussel B, Roby-Brami A, Néris OR, Yakovleff A. Evidence for a spinal stepping generator in man: electrophysiological study. Acta Neurobiol Exp (Wars). 1996;56:465-468. (Pubitemid 26126165)
12. Jankowska E, Jukes MG, Lund S, Lundberg A. The effect of DOPA on the spinal cord. 6. Half-centre organization of interneurones transmitting effects from the flexor reflex afferents. Acta Physiol Scand. 1967; 70:389-402.
13. Berkowitz A, Yosten GL, Ballard RM. Somato-dendritic morphology predicts physiology for neurons that contribute to several kinds of limb movements. J Neurophysiol. 2006;95:2821-2831.
14. Mehrholz J, Kugler J, Pohl M. Locomotor training for walking after spinal cord injury. Cochrane Database Syst Rev. 2008; 2:CD006676.
15. Dobkin B, Apple D, Barbeau H, et al. Weightsupported treadmill vs over-ground training for walking after acute incomplete SCI. Neurology. 2006;66:484-493.
16. Field-Fote EC, Lindley SD, Sherman AL. Locomotor training approaches for individuals with spinal cord injury: a preliminary report of walking-related outcomes. J Neurol Phys Ther. 2005;29:127-137.
17. American Spinal Injury Association/International Spinal Cord Society. Standards for Neurological Classification of Spinal Cord Injury. Chicago, IL: American Spinal Injury Association; 2006.
18. Finch L. Influence of body weight support on normal human gait: development of a gait retraining strategy. Phys Ther. 1991; 71:842-855.
19. Behrman AL, Harkema SJ. Locomotor training after human spinal cord injury: a series of case studies. Phys Ther. 2000;80:688-700. (Pubitemid 30441698)
20. HornbyTG,ZemonDH,CampbellD.Roboticassisted, body-weight-supported treadmill training in individuals following motor incomplete spinal cord injury. Phys Ther. 2005;85:52-66. (Pubitemid 40041547)
21. Nooijen CF, Ter Hoeve N, Field-Fote EC. Gait quality is improved by locomotor training in individuals with SCI regardless of training approach. J Neuroeng Rehabil. 2009;6:36.
22. Musselman KE. Clinical significance testing in rehabilitation research: what, why, and how? Phys Ther Rev. 2007;12:287-296.
23. Perera S, Mody SH, Woodman RC, Studenski SA. Meaningful change and responsiveness in common physical performance measures in older adults. J Am Geriatr Soc. 2006;54:743-749. (Pubitemid 44030194)
24. Rossier P, Wade DT. Validity and reliability comparison of 4 mobility measures in patients presenting with neurologic impairment. Arch Phys Med Rehabil. 2001;82: 9-13. (Pubitemid 32057612)
25. Waters RL, Adkins R, Yakura J, Vigil D. Prediction of ambulatory performance based on motor scores derived from standards of the American Spinal Injury Association. Arch Phys Med Rehabil. 1994;75: 756-760. (Pubitemid 24222070)
26. Zörner B, Blanckenhorn WU, Dietz V, et al. Clinical algorithm for improved prediction of ambulation and patient stratification after incomplete spinal cord injury. J Neurotrauma. 2010;27:241-252.
27. Kim CM, Eng JJ, Whittaker MW. Level walking and ambulatory capacity in persons with incomplete spinal cord injury: relationship with muscle strength. Spinal Cord. 2004;42:156-162. (Pubitemid 38406572)
28. Eng JJ, Chu KS, Dawson AS, et al. Functional walk tests in individuals with stroke: relation to perceived exertion and myocardial Exertion. Stroke. 2002;33:756-761. (Pubitemid 34204003)
29. Grillner S, Ekeberg O , El Manira A, et al. Intrinsic function of a neuronal network: a vertebrate central pattern generator. Brain Res Brain Res Rev. 1998;26:184-197. (Pubitemid 28318075)
30. Gerasimenko YP, Makarovskii AN, Nikitin OA. Control of locomotor activity in humans and animals in the absence of supraspinal influences. Neurosci Behav Physiol. 2002; 32:417-423.
31. Shik ML, Orlovsky GN. Neurophysiology of locomotor automatism. Physiol Rev. 1976;56:465-501.
32. Edgerton VR, Leon RD, Harkema SJ, et al. Retraining the injured spinal cord. J Physiol. 2001;533:15-22. (Pubitemid 32499352)
33. Chang HA, Chuang TY, Lee SJ, et al. Temporal differences in relative phasing of gait initiation and first step length in patients with cervical and lumbosacral spinal cord injuries. Spinal Cord. 2004;42:281-289. (Pubitemid 38903490)
34. Musselman KE, Fouad K, Misiaszek JE, Yang JF. Training of walking skills overground and on the treadmill: case series on individuals with incomplete spinal cord injury. Phys Ther. 2009;89:601-611.
35. Hicks AL, Adams MM, Martin GK, et al. Long-term body-weight-supported treadmill training and subsequent follow-up in persons with chronic SCI: effects on functional walking ability and measures of subjective well-being. Spinal Cord. 2005;43: 291-298. (Pubitemid 40704991)
36. Kleim JA, Jones TA. Principles of experiencedependent neural plasticity: implications for rehabilitation after brain damage. J Speech Lang Hear Res. 2008;51:S225-S239. (Pubitemid 351206588)
37. Forrester LW, Hanley DF, Macko RF. Effects of treadmill exercise on transcranial magnetic stimulation-induced excitability to quadriceps after stroke. Arch Phys Med Rehabil. 2006;87:229-234. (Pubitemid 43151298)
38. Mastos M, Miller K, Eliasson AC, Imms C. Goal-directed training: linking theories of treatment to clinical practice for improved functional activities in daily life. Clin Rehabil. 2007;21:47-55. (Pubitemid 46165306)
39. Dean CM, Ada L, Bampton J, et al. Treadmill walking with body weight support in subacute non-ambulatory stroke improves walking capacity more than overground walking: a randomised trial. J Physiother. 2010;56:97-103.
40. Lee SJ, Hidler J. Biomechanics of overground vs. treadmill walking in healthy individuals. J Appl Physiol. 2008;104:747-755. (Pubitemid 351468804)
41. Reisman DS, Wityk R, Silver K, Bastian AJ. Split-belt treadmill adaptation transfers to overground walking in persons poststroke. Neurorehabil Neural Repair. 2009;23: 735-744.
42. Emken J, Reinkensmeyer D. Robot-enhanced motor learning: accelerating internal model formation during locomotion by transient dynamic amplification. IEEE Trans Neural Syst Rehabil Eng. 2005;13:33-39. (Pubitemid 40469220)
43. Jezernik S, Schärer R, Colombo G, Morari M. Adaptive robotic rehabilitation of locomotion: a clinical study in spinally injured individuals. Spinal Cord. 2003;41:657-666. (Pubitemid 37533127)
44. Lewek MD, Cruz TH, Moore JL, et al. Allowing intralimb kinematic variability during locomotor training poststroke improves kinematic consistency: a subgroup analysis from a randomized clinical trial. Phys Ther. 2009;89:829-839.
45. Jones TA, Chu CJ, Grande LA, Gregory AD. Motor skills training enhances lesioninduced structural plasticity in the motor cortex of adult rats. J Neurosci. 1999;19: 10153-10163. (Pubitemid 30226687)
46. Pohl M, Mehrholz J, Ritschel C, Ruckriem S. Speed-dependent treadmill training in ambulatory hemiparetic stroke patients: a randomized controlled trial. Stroke. 2002; 33:553-558. (Pubitemid 34123405)