In situ photodegradation of incorporated polyanion does not alter prion infectivity

PLoS Pathogens

Volumn 7, Issue 2, 2011, Pages

  Piro, Justin R ^a   Harris, Brent T ^a,b   Supattapone, Surachai ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEASE; POLYANION; PRION PROTEIN; POLYANIONS; POLYMER; POLYTHYMIDYLIC ACID;

ANIMAL TISSUE; ARTICLE; BIOASSAY; BRAIN HOMOGENATE; CONTROLLED STUDY; HAMSTER; IN VITRO STUDY; LIGHT; NEUROPATHOLOGY; NEUROTROPISM; NONHUMAN; PHOTODEGRADATION; PHOTOLYSIS; PRION; PRION DISEASE; PROTEIN FOLDING; ULTRAVIOLET RADIATION; WESTERN BLOTTING; ANIMAL; BIOLOGICAL MODEL; BRAIN STEM; CHEMISTRY; EVALUATION; FEMALE; HIPPOCAMPUS; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PATHOLOGY; RADIATION EXPOSURE; SCRAPIE; SYRIAN HAMSTER; VIRULENCE;

CRICETINAE;

ANIMALS; BASE SEQUENCE; BRAIN STEM; CRICETINAE; FEMALE; HIPPOCAMPUS; LIGHT; MESOCRICETUS; MODELS, BIOLOGICAL; PHOTOLYSIS; POLY T; POLYMERS; PRIONS; PROTEIN FOLDING; SCRAPIE; VIRULENCE;

EID: 79952213489     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002001     Document Type: Article

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