-
1
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
DOI 10.1126/science.1140321
-
Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER III, Hurov KE, Luo J, et al. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 2007;316:1160-6. (Pubitemid 46877472)
-
(2007)
Science
, vol.316
, Issue.5828
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald III, E.R.4
Hurov, K.E.5
Luo, J.6
Bakalarski, C.E.7
Zhao, Z.8
Solimini, N.9
Lerenthal, Y.10
Shiloh, Y.11
Gygi, S.P.12
Elledge, S.J.13
-
2
-
-
0026648941
-
Genetic alterations in the adenoma-carcinoma sequence
-
Cho KR, Vogelstein B. Genetic alterations in the adenoma-carcinoma sequence. Cancer 1992;70:1727-31.
-
(1992)
Cancer
, vol.70
, pp. 1727-1731
-
-
Cho, K.R.1
Vogelstein, B.2
-
3
-
-
39749166975
-
DNA repair pathways as targets for cancer therapy
-
DOI 10.1038/nrc2342, PII NRC2342
-
Helleday T, Petermann E, Lundin C, Hodgson B, Sharma RA. DNA repair pathways as targets for cancer therapy. Nat Rev Cancer 2008;8:193-204. (Pubitemid 351301852)
-
(2008)
Nature Reviews Cancer
, vol.8
, Issue.3
, pp. 193-204
-
-
Helleday, T.1
Petermann, E.2
Lundin, C.3
Hodgson, B.4
Sharma, R.A.5
-
4
-
-
34248184445
-
Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated
-
DOI 10.1172/JCI31245
-
Kennedy RD, Chen CC, Stuckert P, Archila EM, De la Vega MA, Moreau LA, et al. Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J Clin Invest 2007;117:1440-9. (Pubitemid 46718432)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.5
, pp. 1440-1449
-
-
Kennedy, R.D.1
Chen, C.C.2
Stuckert, P.3
Archila, E.M.4
De, L.V.M.A.5
Moreau, L.A.6
Shimamura, A.7
D'Andrea, A.D.8
-
5
-
-
84954358647
-
A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity
-
Amst
-
Lord CJ, McDonald S, Swift S, Turner NC, Ashworth A. A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity. DNA Repair (Amst) 2008;7:2010-9.
-
(2008)
DNA Repair
, vol.7
, pp. 2010-2019
-
-
Lord, C.J.1
McDonald, S.2
Swift, S.3
Turner, N.C.4
Ashworth, A.5
-
6
-
-
0021100690
-
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
-
Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983;11:1475-89.
-
(1983)
Nucleic Acids Res
, vol.11
, pp. 1475-1489
-
-
Dignam, J.D.1
Lebovitz, R.M.2
Roeder, R.G.3
-
7
-
-
33744727981
-
Analysis of DNA repair and chromatin assembly in vitro using immobilized damaged DNA substrates
-
Mello JA, Moggs JG, Almouzni G. Analysis of DNA repair and chromatin assembly in vitro using immobilized damaged DNA substrates. Methods Mol Biol 2006;314:477-87.
-
(2006)
Methods Mol Biol
, vol.314
, pp. 477-487
-
-
Mello, J.A.1
Moggs, J.G.2
Almouzni, G.3
-
8
-
-
0036250827
-
Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway
-
DOI 10.1093/embo-reports/kvf068
-
Mello JA, Sillje HH, Roche DM, Kirschner DB, Nigg EA, Almouzni G. Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. EMBO Rep 2002;3:329-34. (Pubitemid 34467602)
-
(2002)
EMBO Reports
, vol.3
, Issue.4
, pp. 329-334
-
-
Mello, J.A.1
Sillje, H.H.W.2
Roche, D.M.J.3
Kirschner, D.B.4
Nigg, E.A.5
Almouzni, G.6
-
9
-
-
0033980133
-
A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage
-
DOI 10.1128/MCB.20.4.1206-1218.2000
-
Moggs JG, Grandi P, Quivy JP, Jonsson ZO, Hubscher U, Becker PB, et al. A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage. Mol Cell Biol 2000;20:1206-18. (Pubitemid 30069241)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.4
, pp. 1206-1218
-
-
Moggs, J.G.1
Grandi, P.2
Quivy, J.-P.3
Jonsson, Z.O.4
Hubscher, U.5
Becker, P.B.6
Almouzni, G.7
-
10
-
-
0035160267
-
Biopanning and rapid analysis of selective interactive ligands
-
DOI 10.1038/nm1101-1249
-
Giordano RJ, Cardo-Vila M, Lahdenranta J, Pasqualini R, Arap W. Biopanning and rapid analysis of selective interactive ligands. Nat Med 2001;7:1249-53. (Pubitemid 33063782)
-
(2001)
Nature Medicine
, vol.7
, Issue.11
, pp. 1249-1253
-
-
Giordano, R.J.1
Cardo-Vila, M.2
Lahdenranta, J.3
Pasqualini, R.4
Arap, W.5
-
11
-
-
0032535999
-
Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
-
DOI 10.1126/science.279.5349.377
-
Arap W, Pasqualini R, Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 1998;279:377-80. (Pubitemid 28063372)
-
(1998)
Science
, vol.279
, Issue.5349
, pp. 377-380
-
-
Arap, W.1
Pasqualini, R.2
Ruoslahti, E.3
-
12
-
-
79952240275
-
-
Available from cited 2009 Apr 15
-
Available from: http://www.ingenuity.com/ [cited 2009 Apr 15].
-
-
-
-
13
-
-
79952205745
-
-
Available from cited 2009 Apr 13
-
Available from: http://string.embl.de/ [cited 2009 Apr 13].
-
-
-
-
14
-
-
0029819596
-
The domains of mammalian base excision repair enzyme N-methylpurine-DNA glycosylase. Interaction, conformational change, and role in DNA binding and damage recognition
-
Roy R, Kumar A, Lee JC, Mitra S. The domains of mammalian base excision repair enzyme N-methylpurine-DNA glycosylase. Interaction, conformational change, and role in DNA binding and damage recognition. J Biol Chem 1996;271:23690-7.
-
(1996)
J Biol Chem
, vol.271
, pp. 23690-23697
-
-
Roy, R.1
Kumar, A.2
Lee, J.C.3
Mitra, S.4
-
16
-
-
0030630924
-
NCI's anticancer drug screening program may not be selecting for clinically active compounds
-
Brown JM. NCI's anticancer drug screening program may not be selecting for clinically active compounds. Oncol Res 1997;9:213-5.
-
(1997)
Oncol Res
, vol.9
, pp. 213-215
-
-
Brown, J.M.1
-
17
-
-
0031742958
-
The role of DNA single- and double-strand breaks in cell killing by ionizing radiation
-
Olive PL. The role of DNA single- and double-strand breaks in cell killing by ionizing radiation. Radiat Res 1998;150:S42-51.
-
(1998)
Radiat Res
, vol.150
-
-
Olive, P.L.1
-
18
-
-
79952225289
-
-
Available from cited 2009 Apr 9
-
Available from: http://www.ncbi.nlm.nih.gov/blast/ [cited 2009 Apr 9].
-
-
-
-
19
-
-
0030925492
-
KARP-1: A novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity
-
Myung K, He DM, Lee SE, Hendrickson EA. KARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity. EMBO J 1997;16:3172-84.
-
(1997)
EMBO J
, vol.16
, pp. 3172-3184
-
-
Myung, K.1
He, D.M.2
Lee, S.E.3
Hendrickson, E.A.4
-
20
-
-
0029156599
-
DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
-
Hartley KO, Gell D, Smith GC, Zhang H, Divecha N, Connelly MA, et al. DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell 1995;82:849-56.
-
(1995)
Cell
, vol.82
, pp. 849-856
-
-
Hartley, K.O.1
Gell, D.2
Smith, G.C.3
Zhang, H.4
Divecha, N.5
Connelly, M.A.6
-
21
-
-
0028953951
-
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
-
Kirchgessner CU, Patil CK, Evans JW, Cuomo CA, Fried LM, Carter T, et al. DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect. Science 1995;267:1178-83.
-
(1995)
Science
, vol.267
, pp. 1178-1183
-
-
Kirchgessner, C.U.1
Patil, C.K.2
Evans, J.W.3
Cuomo, C.A.4
Fried, L.M.5
Carter, T.6
-
22
-
-
0030009738
-
The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit
-
DOI 10.1074/jbc.271.15.8936
-
Chan DW, Lees-Miller SP. The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit. J Biol Chem 1996;271:8936-41. (Pubitemid 26123320)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.15
, pp. 8936-8941
-
-
Chan, D.W.1
Lees-Miller, S.P.2
-
23
-
-
33646714595
-
Three-Dimensional Structure of the Human DNA-PKcs/Ku70/Ku80 Complex Assembled on DNA and Its Implications for DNA DSB Repair
-
DOI 10.1016/j.molcel.2006.04.013, PII S1097276506002619
-
Spagnolo L, Rivera-Calzada A, Pearl LH, Llorca O. Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair. Mol Cell 2006;22:511-9. (Pubitemid 43740469)
-
(2006)
Molecular Cell
, vol.22
, Issue.4
, pp. 511-519
-
-
Spagnolo, L.1
Rivera-Calzada, A.2
Pearl, L.H.3
Llorca, O.4
-
24
-
-
4544295689
-
Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends
-
DOI 10.1074/jbc.M406432200
-
Reddy Y, Ding Q, Lees-Miller S, Meek K, Ramsden D. Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation- dependent rearrangement at DNA ends. J Biol Chem 2004;279:39408-13. (Pubitemid 39258205)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.38
, pp. 39408-39413
-
-
Reddy, Y.V.R.1
Ding, Q.2
Lees-Miller, S.P.3
Meek, K.4
Ramsden, D.A.5
-
25
-
-
0031984072
-
Trojan peptides: The penetratin system for intracellular delivery
-
DOI 10.1016/S0962-8924(97)01214-2
-
Derossi D, Chassaing G, Prochiantz A. Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol 1998;8:84-7. (Pubitemid 28056816)
-
(1998)
Trends in Cell Biology
, vol.8
, Issue.2
, pp. 84-87
-
-
Derossi, D.1
Chassaing, G.2
Prochiantz, A.3
-
26
-
-
33645229532
-
Alternative pathways for the repair of RAG-induced DNA breaks
-
Weinstock DM, Jasin M. Alternative pathways for the repair of RAG-induced DNA breaks. Mol Cell Biol 2006;26:131-9.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 131-139
-
-
Weinstock, D.M.1
Jasin, M.2
-
27
-
-
39849097680
-
Resistance to therapy caused by intragenic deletion in BRCA2
-
DOI 10.1038/nature06548, PII NATURE06548
-
Edwards SL, Brough R, Lord CJ, Natrajan R, Vatcheva R, Levine DA, et al. Resistance to therapy caused by intragenic deletion in BRCA2. Nature 2008;451:1111-5. (Pubitemid 351317441)
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1111-1115
-
-
Edwards, S.L.1
Brough, R.2
Lord, C.J.3
Natrajan, R.4
Vatcheva, R.5
Levine, D.A.6
Boyd, J.7
Reis-Filho, J.S.8
Ashworth, A.9
-
28
-
-
67650471685
-
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
-
Fong PC, Boss DS, Yap TA, Tutt A, Wu P, Mergui-Roelvink M, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009;361:123-34.
-
(2009)
N Engl J Med
, vol.361
, pp. 123-134
-
-
Fong, P.C.1
Boss, D.S.2
Yap, T.A.3
Tutt, A.4
Wu, P.5
Mergui-Roelvink, M.6
-
29
-
-
67649327114
-
Targeting cancer-specific synthetic lethality in double-strand DNA break repair
-
Moeller BJ, Pasqualini R, Arap W. Targeting cancer-specific synthetic lethality in double-strand DNA break repair. Cell Cycle 2009;8:1872-6.
-
(2009)
Cell Cycle
, vol.8
, pp. 1872-1876
-
-
Moeller, B.J.1
Pasqualini, R.2
Arap, W.3
|