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Volumn 71, Issue 5, 2011, Pages 1816-1824

Discovery of DNA repair inhibitors by combinatorial library profiling

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; LIGAND; NUCLEAR PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE; SYNTHETIC PEPTIDE;

EID: 79952205259     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-2361     Document Type: Article
Times cited : (5)

References (29)
  • 2
    • 0026648941 scopus 로고
    • Genetic alterations in the adenoma-carcinoma sequence
    • Cho KR, Vogelstein B. Genetic alterations in the adenoma-carcinoma sequence. Cancer 1992;70:1727-31.
    • (1992) Cancer , vol.70 , pp. 1727-1731
    • Cho, K.R.1    Vogelstein, B.2
  • 5
    • 84954358647 scopus 로고    scopus 로고
    • A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity
    • Amst
    • Lord CJ, McDonald S, Swift S, Turner NC, Ashworth A. A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity. DNA Repair (Amst) 2008;7:2010-9.
    • (2008) DNA Repair , vol.7 , pp. 2010-2019
    • Lord, C.J.1    McDonald, S.2    Swift, S.3    Turner, N.C.4    Ashworth, A.5
  • 6
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 1983;11:1475-89.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3
  • 7
    • 33744727981 scopus 로고    scopus 로고
    • Analysis of DNA repair and chromatin assembly in vitro using immobilized damaged DNA substrates
    • Mello JA, Moggs JG, Almouzni G. Analysis of DNA repair and chromatin assembly in vitro using immobilized damaged DNA substrates. Methods Mol Biol 2006;314:477-87.
    • (2006) Methods Mol Biol , vol.314 , pp. 477-487
    • Mello, J.A.1    Moggs, J.G.2    Almouzni, G.3
  • 8
    • 0036250827 scopus 로고    scopus 로고
    • Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway
    • DOI 10.1093/embo-reports/kvf068
    • Mello JA, Sillje HH, Roche DM, Kirschner DB, Nigg EA, Almouzni G. Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. EMBO Rep 2002;3:329-34. (Pubitemid 34467602)
    • (2002) EMBO Reports , vol.3 , Issue.4 , pp. 329-334
    • Mello, J.A.1    Sillje, H.H.W.2    Roche, D.M.J.3    Kirschner, D.B.4    Nigg, E.A.5    Almouzni, G.6
  • 11
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • DOI 10.1126/science.279.5349.377
    • Arap W, Pasqualini R, Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 1998;279:377-80. (Pubitemid 28063372)
    • (1998) Science , vol.279 , Issue.5349 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 12
    • 79952240275 scopus 로고    scopus 로고
    • Available from cited 2009 Apr 15
    • Available from: http://www.ingenuity.com/ [cited 2009 Apr 15].
  • 13
    • 79952205745 scopus 로고    scopus 로고
    • Available from cited 2009 Apr 13
    • Available from: http://string.embl.de/ [cited 2009 Apr 13].
  • 14
    • 0029819596 scopus 로고    scopus 로고
    • The domains of mammalian base excision repair enzyme N-methylpurine-DNA glycosylase. Interaction, conformational change, and role in DNA binding and damage recognition
    • Roy R, Kumar A, Lee JC, Mitra S. The domains of mammalian base excision repair enzyme N-methylpurine-DNA glycosylase. Interaction, conformational change, and role in DNA binding and damage recognition. J Biol Chem 1996;271:23690-7.
    • (1996) J Biol Chem , vol.271 , pp. 23690-23697
    • Roy, R.1    Kumar, A.2    Lee, J.C.3    Mitra, S.4
  • 16
    • 0030630924 scopus 로고    scopus 로고
    • NCI's anticancer drug screening program may not be selecting for clinically active compounds
    • Brown JM. NCI's anticancer drug screening program may not be selecting for clinically active compounds. Oncol Res 1997;9:213-5.
    • (1997) Oncol Res , vol.9 , pp. 213-215
    • Brown, J.M.1
  • 17
    • 0031742958 scopus 로고    scopus 로고
    • The role of DNA single- and double-strand breaks in cell killing by ionizing radiation
    • Olive PL. The role of DNA single- and double-strand breaks in cell killing by ionizing radiation. Radiat Res 1998;150:S42-51.
    • (1998) Radiat Res , vol.150
    • Olive, P.L.1
  • 18
    • 79952225289 scopus 로고    scopus 로고
    • Available from cited 2009 Apr 9
    • Available from: http://www.ncbi.nlm.nih.gov/blast/ [cited 2009 Apr 9].
  • 19
    • 0030925492 scopus 로고    scopus 로고
    • KARP-1: A novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity
    • Myung K, He DM, Lee SE, Hendrickson EA. KARP-1: a novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity. EMBO J 1997;16:3172-84.
    • (1997) EMBO J , vol.16 , pp. 3172-3184
    • Myung, K.1    He, D.M.2    Lee, S.E.3    Hendrickson, E.A.4
  • 20
    • 0029156599 scopus 로고
    • DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
    • Hartley KO, Gell D, Smith GC, Zhang H, Divecha N, Connelly MA, et al. DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell 1995;82:849-56.
    • (1995) Cell , vol.82 , pp. 849-856
    • Hartley, K.O.1    Gell, D.2    Smith, G.C.3    Zhang, H.4    Divecha, N.5    Connelly, M.A.6
  • 22
    • 0030009738 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit
    • DOI 10.1074/jbc.271.15.8936
    • Chan DW, Lees-Miller SP. The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit. J Biol Chem 1996;271:8936-41. (Pubitemid 26123320)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.15 , pp. 8936-8941
    • Chan, D.W.1    Lees-Miller, S.P.2
  • 23
    • 33646714595 scopus 로고    scopus 로고
    • Three-Dimensional Structure of the Human DNA-PKcs/Ku70/Ku80 Complex Assembled on DNA and Its Implications for DNA DSB Repair
    • DOI 10.1016/j.molcel.2006.04.013, PII S1097276506002619
    • Spagnolo L, Rivera-Calzada A, Pearl LH, Llorca O. Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair. Mol Cell 2006;22:511-9. (Pubitemid 43740469)
    • (2006) Molecular Cell , vol.22 , Issue.4 , pp. 511-519
    • Spagnolo, L.1    Rivera-Calzada, A.2    Pearl, L.H.3    Llorca, O.4
  • 24
    • 4544295689 scopus 로고    scopus 로고
    • Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation-dependent rearrangement at DNA ends
    • DOI 10.1074/jbc.M406432200
    • Reddy Y, Ding Q, Lees-Miller S, Meek K, Ramsden D. Non-homologous end joining requires that the DNA-PK complex undergo an autophosphorylation- dependent rearrangement at DNA ends. J Biol Chem 2004;279:39408-13. (Pubitemid 39258205)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.38 , pp. 39408-39413
    • Reddy, Y.V.R.1    Ding, Q.2    Lees-Miller, S.P.3    Meek, K.4    Ramsden, D.A.5
  • 25
    • 0031984072 scopus 로고    scopus 로고
    • Trojan peptides: The penetratin system for intracellular delivery
    • DOI 10.1016/S0962-8924(97)01214-2
    • Derossi D, Chassaing G, Prochiantz A. Trojan peptides: the penetratin system for intracellular delivery. Trends Cell Biol 1998;8:84-7. (Pubitemid 28056816)
    • (1998) Trends in Cell Biology , vol.8 , Issue.2 , pp. 84-87
    • Derossi, D.1    Chassaing, G.2    Prochiantz, A.3
  • 26
    • 33645229532 scopus 로고    scopus 로고
    • Alternative pathways for the repair of RAG-induced DNA breaks
    • Weinstock DM, Jasin M. Alternative pathways for the repair of RAG-induced DNA breaks. Mol Cell Biol 2006;26:131-9.
    • (2006) Mol Cell Biol , vol.26 , pp. 131-139
    • Weinstock, D.M.1    Jasin, M.2
  • 28
    • 67650471685 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
    • Fong PC, Boss DS, Yap TA, Tutt A, Wu P, Mergui-Roelvink M, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med 2009;361:123-34.
    • (2009) N Engl J Med , vol.361 , pp. 123-134
    • Fong, P.C.1    Boss, D.S.2    Yap, T.A.3    Tutt, A.4    Wu, P.5    Mergui-Roelvink, M.6
  • 29
    • 67649327114 scopus 로고    scopus 로고
    • Targeting cancer-specific synthetic lethality in double-strand DNA break repair
    • Moeller BJ, Pasqualini R, Arap W. Targeting cancer-specific synthetic lethality in double-strand DNA break repair. Cell Cycle 2009;8:1872-6.
    • (2009) Cell Cycle , vol.8 , pp. 1872-1876
    • Moeller, B.J.1    Pasqualini, R.2    Arap, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.