메뉴 건너뛰기




Volumn 679, Issue , 2011, Pages 165-182

Enzyme–Nanoparticle Conjugates for Biomedical Applications

Author keywords

Antibody; Biodegradable nanoparticles; Conjugates; PLGA; Targeted delivery; Therapeutic enzymes

Indexed keywords

ENZYME; LACTIC ACID; LIPOSOME; LYSOZYME; NANOPARTICLE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; SUPEROXIDE DISMUTASE;

EID: 79952197794     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-60761-895-9_14     Document Type: Chapter
Times cited : (18)

References (86)
  • 1
    • 84913976135 scopus 로고
    • Enzyme engineering and its application in lysosomal storage disease
    • S. Mumtaz and B. K. Bachhawat, Enzyme engineering and its application in lysosomal storage disease, Pure and Applied Chemistry 64 (1992), no. 8, 1055–1060.
    • (1992) Pure and Applied Chemistry , vol.64 , Issue.8 , pp. 1055-1060
    • Mumtaz, S.1    Bachhawat, B.K.2
  • 3
    • 0029895325 scopus 로고    scopus 로고
    • Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic considerations on biodistribu-tion
    • Y. Takakura and M. Hashida, Macromolecular carrier systems for targeted drug delivery: Pharmacokinetic considerations on biodistribu-tion, Pharmaceutical Research 13 (1996), no. 6, 820–831.
    • (1996) Pharmaceutical Research , vol.13 , Issue.6 , pp. 820-831
    • Takakura, Y.1    Hashida, M.2
  • 4
    • 28744440876 scopus 로고    scopus 로고
    • Tumour-targeted drug and gene delivery: Principles and concepts
    • J. Cassidy and A. G. Schätzlein, Tumour-targeted drug and gene delivery: Principles and concepts, Expert Reviews in Molecular Medicine 6 (2004), no. 19, 1–17.
    • (2004) Expert Reviews in Molecular Medicine , vol.6 , Issue.19 , pp. 1-17
    • Cassidy, J.1    Schätzlein, A.G.2
  • 5
    • 0042242757 scopus 로고    scopus 로고
    • Chimeric TNT-3/human beta-glucuronidase fusion proteins for antibody-directed enzyme prodrug therapy (ADEPT)
    • B. H. Biela, L. A. Khawli, P. Hu and A. L. Epstein, Chimeric TNT-3/human beta-glucuronidase fusion proteins for antibody-directed enzyme prodrug therapy (ADEPT), Cancer Biotherapy & Radiopharmaceuticals 18 (2003), no. 3, 339–353.
    • (2003) Cancer Biotherapy & Radiopharmaceuticals , vol.18 , Issue.3 , pp. 339-353
    • Biela, B.H.1    Khawli, L.A.2    Hu, P.3    Epstein, A.L.4
  • 6
    • 0015147978 scopus 로고
    • Immunocolloid method for electron microscope
    • W. P. Faulk and G. M. Taylor, Immunocolloid method for electron microscope, Immunochem-istry 8 (1971), no. 11, 1081–1083.
    • (1971) Immunochem-Istry , vol.8 , Issue.11 , pp. 1081-1083
    • Faulk, W.P.1    Taylor, G.M.2
  • 7
    • 10044277018 scopus 로고    scopus 로고
    • Protein adsorption onto silica nanoparticles: Conformational changes depend on the parti-cles’ curvature and the protein stability
    • M. Lundqvist, I. Sethson and B. H. Jonsson, Protein adsorption onto silica nanoparticles: Conformational changes depend on the parti-cles’ curvature and the protein stability, Langmuir 20 (2004), no. 24, 10639–10647.
    • (2004) Langmuir , vol.20 , Issue.24 , pp. 10639-10647
    • Lundqvist, M.1    Sethson, I.2    Jonsson, B.H.3
  • 8
    • 18744381831 scopus 로고    scopus 로고
    • Functionalized gold nanoparticles for applications in bionanotechnology
    • W. R. Glomm, Functionalized gold nanoparticles for applications in bionanotechnology, Journal of Dispersion Science and Technology 26 (2005), no. 3, 389–414.
    • (2005) Journal of Dispersion Science and Technology , vol.26 , Issue.3 , pp. 389-414
    • Glomm, W.R.1
  • 10
    • 0025470458 scopus 로고
    • The adsorption of bovine serum-albumin on positively and negatively charged polystyrene lattices
    • A. V. Elgersma, R. L. J. Zsom, W. Norde and J. Lyklema, The adsorption of bovine serum-albumin on positively and negatively charged polystyrene lattices, Journal of Colloid and Interface Science 138 (1990), no. 1, 145–156.
    • (1990) Journal of Colloid and Interface Science , vol.138 , Issue.1 , pp. 145-156
    • Elgersma, A.V.1    Zsom, R.L.J.2    Norde, W.3    Lyklema, J.4
  • 13
    • 0141868926 scopus 로고    scopus 로고
    • Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins
    • J. M. Nam, C. S. Thaxton and C. A. Mirkin, Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins, Science 301 (2003), no. 5641, 1884–1886.
    • (2003) Science , vol.301 , Issue.5641 , pp. 1884-1886
    • Nam, J.M.1    Thaxton, C.S.2    Mirkin, C.A.3
  • 14
    • 0035915124 scopus 로고    scopus 로고
    • Nanoparticles, proteins, and nucleic acids: Biotechnology meets materials science
    • C. M. Niemeyer, Nanoparticles, proteins, and nucleic acids: Biotechnology meets materials science, Angewandte Chemie – International Edition 40 (2001), no. 22, 4128–4158.
    • (2001) Angewandte Chemie – International Edition , vol.40 , Issue.22 , pp. 4128-4158
    • Niemeyer, C.M.1
  • 15
    • 0034975227 scopus 로고    scopus 로고
    • Mechanisms of enhanced osteoblast adhesion on nanophase alumina involve vit-ronectin
    • T. J. Webster, L. S. Schadler, R. W. Siegel and R. Bizios, Mechanisms of enhanced osteoblast adhesion on nanophase alumina involve vit-ronectin, Tissue Engineering 7 (2001), no. 3, 291–301.
    • (2001) Tissue Engineering , vol.7 , Issue.3 , pp. 291-301
    • Webster, T.J.1    Schadler, L.S.2    Siegel, R.W.3    Bizios, R.4
  • 16
    • 0033527089 scopus 로고    scopus 로고
    • Activity losses among T4 lysozyme charge variants after adsorption to colloidal silica
    • C. K. Bower, S. Sananikone, M. K. Bothwell and J. McGuire, Activity losses among T4 lysozyme charge variants after adsorption to colloidal silica, Biotechnology and Bioengineering 64 (1999), no. 3, 373–376.
    • (1999) Biotechnology and Bioengineering , vol.64 , Issue.3 , pp. 373-376
    • Bower, C.K.1    Sananikone, S.2    Bothwell, M.K.3    McGuire, J.4
  • 17
    • 0035862841 scopus 로고    scopus 로고
    • Effect of temperature on the conformation of lysozyme adsorbed to silica particles
    • C. Czeslik and R. Winter, Effect of temperature on the conformation of lysozyme adsorbed to silica particles, Physical Chemistry Chemical Physics 3 (2001), no. 2, 235–239.
    • (2001) Physical Chemistry Chemical Physics , vol.3 , Issue.2 , pp. 235-239
    • Czeslik, C.1    Winter, R.2
  • 18
    • 0027273014 scopus 로고
    • Kinetic and circular-dichroism studies of enzymes adsorbed on ultrafine silica particles
    • A. Kondo, F. Murakami, M. Kawagoe and K. Higashitani, Kinetic and circular-dichroism studies of enzymes adsorbed on ultrafine silica particles, Applied Microbiology and Biotechnology 39 (1993), no. 6, 726–731.
    • (1993) Applied Microbiology and Biotechnology , vol.39 , Issue.6 , pp. 726-731
    • Kondo, A.1    Murakami, F.2    Kawagoe, M.3    Higashitani, K.4
  • 19
    • 44049111617 scopus 로고
    • Adsorption, desorption and readsorption of proteins on solid-surfaces
    • W. Norde and A. C. I. Anusiem, Adsorption, desorption and readsorption of proteins on solid-surfaces, Colloids and Surfaces 66 (1992), no. 1, 73–80.
    • (1992) Colloids and Surfaces , vol.66 , Issue.1 , pp. 73-80
    • Norde, W.1    Anusiem, A.C.I.2
  • 22
    • 27844518415 scopus 로고    scopus 로고
    • Nanostructures for enzyme stabilization
    • J. Kim, J. W. Grate and P. Wang, Nanostructures for enzyme stabilization, Chemical Engineering Science 61 (2006), no. 3, 1017–1026.
    • (2006) Chemical Engineering Science , vol.61 , Issue.3 , pp. 1017-1026
    • Kim, J.1    Grate, J.W.2    Wang, P.3
  • 23
    • 4043075579 scopus 로고    scopus 로고
    • Silica nanoparticle size influences the structure and enzymatic activity of adsorbed lysozyme
    • A. A. Vertegel, R. W. Siegel and J. S. Dordick, Silica nanoparticle size influences the structure and enzymatic activity of adsorbed lysozyme, Langmuir 20 (2004), no. 16, 6800–6807.
    • (2004) Langmuir , vol.20 , Issue.16 , pp. 6800-6807
    • Vertegel, A.A.1    Siegel, R.W.2    Dordick, J.S.3
  • 26
    • 57649243749 scopus 로고    scopus 로고
    • Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro
    • E. J. Park and K. Park, Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro, Toxicology Letters 184 (2009), no. 1, 18–25.
    • (2009) Toxicology Letters , vol.184 , Issue.1 , pp. 18-25
    • Park, E.J.1    Park, K.2
  • 27
    • 58149107469 scopus 로고    scopus 로고
    • Impact of oxidative stress on lung diseases
    • H. S. Park, S. R. Kim and Y. C. Lee, Impact of oxidative stress on lung diseases, Respirology 14 (2009), no. 1, 27–38.
    • (2009) Respirology , vol.14 , Issue.1 , pp. 27-38
    • Park, H.S.1    Kim, S.R.2    Lee, Y.C.3
  • 28
    • 0142169940 scopus 로고    scopus 로고
    • Oxidative stress and gene transcription in asthma and chronic obstructive pulmonary disease: Antioxidant therapeutic targets
    • I. Rahman, Oxidative stress and gene transcription in asthma and chronic obstructive pulmonary disease: Antioxidant therapeutic targets, Current Drug Targets. Inflammation and Allergy 1 (2002), no. 3, 291–315.
    • (2002) Current Drug Targets. Inflammation and Allergy , vol.1 , Issue.3 , pp. 291-315
    • Rahman, I.1
  • 30
    • 0344299171 scopus 로고    scopus 로고
    • NADPH oxidase is functionally assembled in specific granules during activation of human neutrophils
    • C. Vaissiere, V. Le Cabec and I. Maridonneau-Parini, NADPH oxidase is functionally assembled in specific granules during activation of human neutrophils, Journal of Leukocyte Biology 65 (1999), no. 5, 629–634.
    • (1999) Journal of Leukocyte Biology , vol.65 , Issue.5 , pp. 629-634
    • Vaissiere, C.1    Le Cabec, V.2    Maridonneau-Parini, I.3
  • 31
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase – role in cardiovascular biology and disease
    • K. K. Griendling, D. Sorescu and M. Ushio-Fukai, NAD(P)H oxidase – role in cardiovascular biology and disease, Circulation Research 86 (2000), no. 5, 494–501.
    • (2000) Circulation Research , vol.86 , Issue.5 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 32
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: New discoveries and insights
    • A. S. Baldwin, The NF-kappa B and I kappa B proteins: New discoveries and insights, Annual Review of Immunology 14 (1996), 649–683.
    • (1996) Annual Review of Immunology , vol.14 , pp. 649-683
    • Baldwin, A.S.1
  • 35
    • 34347242634 scopus 로고    scopus 로고
    • Therapeutic potential of superoxide dismutase (SOD) for resolution of inflammation
    • K. Yasui and A. Baba, Therapeutic potential of superoxide dismutase (SOD) for resolution of inflammation, Inflammation Research 55 (2006), no. 9, 359–363.
    • (2006) Inflammation Research , vol.55 , Issue.9 , pp. 359-363
    • Yasui, K.1    Baba, A.2
  • 36
    • 0035897870 scopus 로고    scopus 로고
    • Oxidative stress and human disease: Current knowledge and perspectives for prevention
    • M. P. Lehucker-Michel, J. F. Lesgards, O. Delubac, P. Stocker, P. Durand and M. Prost, Oxidative stress and human disease: Current knowledge and perspectives for prevention, Presse Médicale 30 (2001), no. 21, 1076–1081.
    • (2001) Presse Médicale , vol.30 , Issue.21 , pp. 1076-1081
    • Lehucker-Michel, M.P.1    Lesgards, J.F.2    Delubac, O.3    Stocker, P.4    Durand, P.5    Prost, M.6
  • 37
    • 0029740875 scopus 로고    scopus 로고
    • Role of oxidants/ antioxidants in smoking-induced lung diseases
    • I. Rahman and W. MacNee, Role of oxidants/ antioxidants in smoking-induced lung diseases, Free Radical Biology and Medicine 21 (1996), no. 5, 669–681.
    • (1996) Free Radical Biology and Medicine , vol.21 , Issue.5 , pp. 669-681
    • Rahman, I.1    Macnee, W.2
  • 38
    • 0029823184 scopus 로고    scopus 로고
    • Role of superoxide anions in airway hyperresponsiveness induced by cigarette smoke in conscious guinea pigs
    • M. Nishikawa, M. Kudo, N. Kakemizu, H. Ikeda and T. Okubo, Role of superoxide anions in airway hyperresponsiveness induced by cigarette smoke in conscious guinea pigs, Lung 174 (1996), no. 5, 279–289.
    • (1996) Lung , vol.174 , Issue.5 , pp. 279-289
    • Nishikawa, M.1    Kudo, M.2    Kakemizu, N.3    Ikeda, H.4    Okubo, T.5
  • 39
    • 0026437385 scopus 로고
    • Superoxide formed from cigarette-smoke impairs polymorphonu-clear leukocyte active oxygen generation activity
    • M. Tsuchiya, D. F. T. Thompson, Y. J. Suzuki, C. E. Cross and L. Packer, Superoxide formed from cigarette-smoke impairs polymorphonu-clear leukocyte active oxygen generation activity, Archives of Biochemistry and Biophysics 299 (1992), no. 1, 30–37.
    • (1992) Archives of Biochemistry and Biophysics , vol.299 , Issue.1 , pp. 30-37
    • Tsuchiya, M.1    Thompson, D.F.T.2    Suzuki, Y.J.3    Cross, C.E.4    Packer, L.5
  • 40
    • 58249099942 scopus 로고    scopus 로고
    • COPD as a disease of accelerated lung aging
    • K. Ito and P. J. Barnes, COPD as a disease of accelerated lung aging, Chest 135 (2009), no. 1, 173–180.
    • (2009) Chest , vol.135 , Issue.1 , pp. 173-180
    • Ito, K.1    Barnes, P.J.2
  • 41
    • 0023196326 scopus 로고
    • Cigarette smoke and the involvement of free radical reactions in chemical car-cinogenesis
    • W. A. Pryor, Cigarette smoke and the involvement of free radical reactions in chemical car-cinogenesis, British Journal of Cancer. Supplement 55 (1987), no. VIII, 19–23.
    • (1987) British Journal of Cancer. Supplement , vol.55
    • Pryor, W.A.1
  • 42
    • 0022272160 scopus 로고
    • Free-radical chemistry of cigarette-smoke and its toxicological implications
    • D. F. Church and W. A. Pryor, Free-radical chemistry of cigarette-smoke and its toxicological implications, Environmental Health Perspectives 64 (1985), 111–126.
    • (1985) Environmental Health Perspectives , vol.64 , pp. 111-126
    • Church, D.F.1    Pryor, W.A.2
  • 43
    • 0025980451 scopus 로고
    • Oxidative stress status – an introduction
    • W. A. Pryor and S. S. Godber, Oxidative stress status – an introduction, Free Radical Biology and Medicine 10 (1991), no. 3–4, 173–173.
    • (1991) Free Radical Biology and Medicine , vol.10 , Issue.3-4 , pp. 173-173
    • Pryor, W.A.1    Godber, S.S.2
  • 44
    • 0024351881 scopus 로고
    • Quantitative-analysis of the hydrogen-peroxide formed in aqueous cigarette tar extracts
    • T. Nakayama, D. F. Church and W. A. Pryor, Quantitative-analysis of the hydrogen-peroxide formed in aqueous cigarette tar extracts, Free Radical Biology and Medicine 7 (1989), no. 1, 9–15.
    • (1989) Free Radical Biology and Medicine , vol.7 , Issue.1 , pp. 9-15
    • Nakayama, T.1    Church, D.F.2    Pryor, W.A.3
  • 45
    • 0021345443 scopus 로고
    • Generation of hydrogen-peroxide and superoxide anion radical from cigarette-smoke
    • T. Nakayama, M. Kodama and C. Nagata, Generation of hydrogen-peroxide and superoxide anion radical from cigarette-smoke, Gann 75 (1984), no. 2, 95–98.
    • (1984) Gann , vol.75 , Issue.2 , pp. 95-98
    • Nakayama, T.1    Kodama, M.2    Nagata, C.3
  • 46
    • 0033071046 scopus 로고    scopus 로고
    • Superoxide mediates cigarette smoke-induced infiltration of neutrophils into the airways through nuclear factor-kappa b activation and IL-8 mRNA expression in guinea pigs in vivo
    • M. Nishikawa, N. Kakemizu, T. Ito, M. Kudo, T. Kaneko, M. Suzuki, N. Udaka, H. Ikeda and T. Okubo, Superoxide mediates cigarette smoke-induced infiltration of neutrophils into the airways through nuclear factor-kappa b activation and IL-8 mRNA expression in guinea pigs in vivo, American Journal of Respiratory Cell and Molecular Biology 20 (1999), no. 2, 189–198.
    • (1999) American Journal of Respiratory Cell and Molecular Biology , vol.20 , Issue.2 , pp. 189-198
    • Nishikawa, M.1    Kakemizu, N.2    Ito, T.3    Kudo, M.4    Kaneko, T.5    Suzuki, M.6    Udaka, N.7    Ikeda, H.8    Okubo, T.9
  • 48
    • 0345517291 scopus 로고    scopus 로고
    • Effect of superoxide dismutase from bovine erythrocytes on different activity parameters in adjuvant-induced arthritis
    • A. Garcia-Gonzalez, J. Herrera-Abarca and J. L. Ochoa, Effect of superoxide dismutase from bovine erythrocytes on different activity parameters in adjuvant-induced arthritis, Archives of Medical Research 30 (1999), no. 2, 132–137.
    • (1999) Archives of Medical Research , vol.30 , Issue.2 , pp. 132-137
    • Garcia-Gonzalez, A.1    Herrera-Abarca, J.2    Ochoa, J.L.3
  • 49
    • 15444380718 scopus 로고    scopus 로고
    • Superoxide dismutase failed to attenuate allergen-induced nasal congestion in ragweed-sensitized dogs
    • N. Skorohod and D. B. Yeates, Superoxide dismutase failed to attenuate allergen-induced nasal congestion in ragweed-sensitized dogs, Journal of Applied Physiology 98 (2005), no. 4, 1478–1486.
    • (2005) Journal of Applied Physiology , vol.98 , Issue.4 , pp. 1478-1486
    • Skorohod, N.1    Yeates, D.B.2
  • 51
    • 0033044372 scopus 로고    scopus 로고
    • Improved pulmonary distribution of recombinant human Cu/Zn superoxide dismutase, using a modified ultrasonic nebulizer
    • E. G. Langenback, J. M. Davis, C. Robbins, N. Sahgal, R. J. Perry and S. R. Simon, Improved pulmonary distribution of recombinant human Cu/Zn superoxide dismutase, using a modified ultrasonic nebulizer, Pediatric Pulmonology 27 (1999), no. 2, 124–129.
    • (1999) Pediatric Pulmonology , vol.27 , Issue.2 , pp. 124-129
    • Langenback, E.G.1    Davis, J.M.2    Robbins, C.3    Sahgal, N.4    Perry, R.J.5    Simon, S.R.6
  • 52
    • 33644789549 scopus 로고    scopus 로고
    • Biodegradable microspheres as carriers for native superoxide dismutase and catalase delivery
    • S. Giovagnoli, P. Blasi, M. Ricci and C. Rossi, Biodegradable microspheres as carriers for native superoxide dismutase and catalase delivery, AAPS Pharmscitech 5 (2004), no. 4, e51.
    • (2004) AAPS Pharmscitech , vol.5 , Issue.4 , pp. e51
    • Giovagnoli, S.1    Blasi, P.2    Ricci, M.3    Rossi, C.4
  • 53
    • 24344495365 scopus 로고    scopus 로고
    • Long-term delivery of superoxide dismutase and catalase entrapped in poly(lactide-co-glycolide) microspheres: In vitro effects on isolated neonatal porcine pancreatic cell clusters
    • S. Giovagnoli, G. Luca, I. Casaburi, P. Blasi, G. Macchiarulo, M. Ricci, M. Calvitti, G. Basta, R. Calafiore and C. Rossi, Long-term delivery of superoxide dismutase and catalase entrapped in poly(lactide-co-glycolide) microspheres: In vitro effects on isolated neonatal porcine pancreatic cell clusters, Journal of Controlled Release 107 (2005), no. 1, 65–77.
    • (2005) Journal of Controlled Release , vol.107 , Issue.1 , pp. 65-77
    • Giovagnoli, S.1    Luca, G.2    Casaburi, I.3    Blasi, P.4    Macchiarulo, G.5    Ricci, M.6    Calvitti, M.7    Basta, G.8    Calafiore, R.9    Rossi, C.10
  • 55
    • 33846456612 scopus 로고    scopus 로고
    • Polyketal microparticles: A new delivery vehicle for superoxide dismutase
    • S. Lee, S. C. Yang, M. J. Heffernan, W. R. Taylor and N. Murthy, Polyketal microparticles: A new delivery vehicle for superoxide dismutase, Bioconjugate Chemistry 18 (2007), no. 1, 4–7.
    • (2007) Bioconjugate Chemistry , vol.18 , Issue.1 , pp. 4-7
    • Lee, S.1    Yang, S.C.2    Heffernan, M.J.3    Taylor, W.R.4    Murthy, N.5
  • 57
    • 58149202714 scopus 로고    scopus 로고
    • Superoxide dismutase-loaded PLGA nanoparticles protect cultured human neurons under oxidative stress
    • M. K. Reddy, L. Wu, W. Kou, A. Ghorpade and V. Labhasetwar, Superoxide dismutase-loaded PLGA nanoparticles protect cultured human neurons under oxidative stress, Applied Biochemistry and Biotechnology 151 (2008), no. 2–3, 565–577.
    • (2008) Applied Biochemistry and Biotechnology , vol.151 , Issue.2-3 , pp. 565-577
    • Reddy, M.K.1    Wu, L.2    Kou, W.3    Ghorpade, A.4    Labhasetwar, V.5
  • 58
    • 68149160611 scopus 로고    scopus 로고
    • Nanoparticle-mediated delivery of superoxide dismutase to the brain: An effective strategy to reduce ischemia-reperfusion injury
    • M. K. Reddy and V. Labhasetwar, Nanoparticle-mediated delivery of superoxide dismutase to the brain: An effective strategy to reduce ischemia-reperfusion injury, FASEB Journal 23 (2009), no. 5, 1384–1395.
    • (2009) FASEB Journal , vol.23 , Issue.5 , pp. 1384-1395
    • Reddy, M.K.1    Labhasetwar, V.2
  • 59
    • 6944255523 scopus 로고    scopus 로고
    • Delivery of therapeutic agents to the central nervous system: The problems and the possibilities
    • D. J. Begley, Delivery of therapeutic agents to the central nervous system: The problems and the possibilities, Pharmacology & Therapeutics 104 (2004), no. 1, 29–45.
    • (2004) Pharmacology & Therapeutics , vol.104 , Issue.1 , pp. 29-45
    • Begley, D.J.1
  • 60
    • 0031765572 scopus 로고    scopus 로고
    • Nanoparticle technology for delivery of drugs across the blood–brain barrier
    • U. Schroeder, P. Sommerfeld, S. Ulrich and B. A. Sabel, Nanoparticle technology for delivery of drugs across the blood–brain barrier, Journal of Pharmaceutical Sciences 87 (1998), no. 11, 1305–1307.
    • (1998) Journal of Pharmaceutical Sciences , vol.87 , Issue.11 , pp. 1305-1307
    • Schroeder, U.1    Sommerfeld, P.2    Ulrich, S.3    Sabel, B.A.4
  • 61
    • 70350048977 scopus 로고    scopus 로고
    • Protein–nanoparticle conjugates as a potential therapeutic agents for treatment of secondary spinal cord injury, Proceedings of the MRS
    • V. Reukov, J. Olbrich, R. Satishkumar and A. Vertegel, Protein–nanoparticle conjugates as a potential therapeutic agents for treatment of secondary spinal cord injury, Proceedings of the MRS 2007 Fall Meeting, Materials Research Society, 2007, 6–16.
    • (2007) Fall Meeting, Materials Research Society , vol.2007 , pp. 6-16
    • Reukov, V.1    Olbrich, J.2    Satishkumar, R.3    Vertegel, A.4
  • 63
    • 0024497763 scopus 로고
    • Innovative approaches to plasminogen-activator therapy
    • E. Haber, T. Quertermous, G. R. Matsueda and M. S. Runge, Innovative approaches to plasminogen-activator therapy, Science 243 (1989), no. 4887, 51–56.
    • (1989) Science , vol.243 , Issue.4887 , pp. 51-56
    • Haber, E.1    Quertermous, T.2    Matsueda, G.R.3    Runge, M.S.4
  • 64
    • 0029831115 scopus 로고    scopus 로고
    • Thrombolytic therapy in acute myocar-dial infarction – update
    • K. Huber, M. S. Runge, C. Bode and D. Gulba, Thrombolytic therapy in acute myocar-dial infarction – update 1996, Annals of Hematology 73 (1996), S29–S38.
    • (1996) Annals of Hematology , vol.73 , Issue.1996 , pp. S29-S38
    • Huber, K.1    Runge, M.S.2    Bode, C.3    Gulba, D.4
  • 65
    • 0025193797 scopus 로고
    • Local prevention of thrombosis in animal arteries by means of magnetic targeting of aspirin-loaded red-cells
    • N. M. Orekhova, R. S. Akchurin, A. A. Belyaev, M. D. Smirnov, S. E. Ragimov and A. N. Orekhov, Local prevention of thrombosis in animal arteries by means of magnetic targeting of aspirin-loaded red-cells, Thrombosis Research 57 (1990), no. 4, 611–616.
    • (1990) Thrombosis Research , vol.57 , Issue.4 , pp. 611-616
    • Orekhova, N.M.1    Akchurin, R.S.2    Belyaev, A.A.3    Smirnov, M.D.4    Ragimov, S.E.5    Orekhov, A.N.6
  • 67
  • 69
    • 33947123115 scopus 로고    scopus 로고
    • Intra-arterial application of magnetic nanoparticles for targeted thrombolytic therapy: A rat embolic model
    • Y. H. Ma, Y. W. Hsu, Y. J. Chang, M. Y. Hua, J. P. Chen and T. Wu, Intra-arterial application of magnetic nanoparticles for targeted thrombolytic therapy: A rat embolic model, Journal of Magnetism and Magnetic Materials 311 (2007), no. 1, 342–346.
    • (2007) Journal of Magnetism and Magnetic Materials , vol.311 , Issue.1 , pp. 342-346
    • Ma, Y.H.1    Hsu, Y.W.2    Chang, Y.J.3    Hua, M.Y.4    Chen, J.P.5    Wu, T.6
  • 72
    • 33947325967 scopus 로고    scopus 로고
    • Ultrasound-facilitated thromboly-sis using tissue-plasminogen activator-loaded echogenic liposomes
    • S. D. Tiukinhoy-Laing, S. L. Huang, M. Klegerman, C. K. Holland and D. D. McPherson, Ultrasound-facilitated thromboly-sis using tissue-plasminogen activator-loaded echogenic liposomes, Thrombosis Research 119 (2007), no. 6, 777–784.
    • (2007) Thrombosis Research , vol.119 , Issue.6 , pp. 777-784
    • Tiukinhoy-Laing, S.D.1    Huang, S.L.2    Klegerman, M.3    Holland, C.K.4    McPherson, D.D.5
  • 75
    • 33947418509 scopus 로고    scopus 로고
    • Multifunctional antimicrobial peptides: Therapeutic targets in several human diseases
    • M. Zaiou, Multifunctional antimicrobial peptides: Therapeutic targets in several human diseases, Journal of Molecular Medicine 85 (2007), no. 4, 317–329.
    • (2007) Journal of Molecular Medicine , vol.85 , Issue.4 , pp. 317-329
    • Zaiou, M.1
  • 76
    • 28444489291 scopus 로고    scopus 로고
    • Protective roles of the skin against infection: Implication of naturally occurring human antimicrobial agents beta-defensins, cathelicidin LL-37 and lysozyme
    • F. Niyonsaba and H. Ogawa, Protective roles of the skin against infection: Implication of naturally occurring human antimicrobial agents beta-defensins, cathelicidin LL-37 and lysozyme, Journal of Dermatological Science 40 (2005), no. 3, 157–168.
    • (2005) Journal of Dermatological Science , vol.40 , Issue.3 , pp. 157-168
    • Niyonsaba, F.1    Ogawa, H.2
  • 77
    • 0017288984 scopus 로고
    • New adjuvants on a polymethylmethacrylate base
    • J. Kreuter and P. P. Speiser, New adjuvants on a polymethylmethacrylate base, Infection and Immunity 13 (1976), no. 1, 204–210.
    • (1976) Infection and Immunity , vol.13 , Issue.1 , pp. 204-210
    • Kreuter, J.1    Speiser, P.P.2
  • 85
    • 34547783898 scopus 로고    scopus 로고
    • Enhancing antimicrobial activity of lysozyme against Listeria monocy-togenes using immunonanoparticles
    • H. Yang, L. W. Qu, A. Wimbrow, X. P. Jiang and Y. P. Sun, Enhancing antimicrobial activity of lysozyme against Listeria monocy-togenes using immunonanoparticles, Journal of Food Protection 70 (2007), no. 8, 1844–1849.
    • (2007) Journal of Food Protection , vol.70 , Issue.8 , pp. 1844-1849
    • Yang, H.1    Qu, L.W.2    Wimbrow, A.3    Jiang, X.P.4    Sun, Y.P.5
  • 86
    • 44049100413 scopus 로고    scopus 로고
    • Charge-directed targeting of antimicrobial protein– nanoparticle conjugates
    • R. Satishkumar and A. Vertegel, Charge-directed targeting of antimicrobial protein– nanoparticle conjugates, Biotechnology and Bioengineering 100 (2008), no. 3, 403–412.
    • (2008) Biotechnology and Bioengineering , vol.100 , Issue.3 , pp. 403-412
    • Satishkumar, R.1    Vertegel, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.