Striatal and cortical BOLD, blood flow, blood volume, oxygen consumption, and glucose consumption changes in noxious forepaw electrical stimulation

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 3, 2011, Pages 832-841

  Shih, Yen Yu I ^a   Wey, Hsiao Ying ^a   De La Garza, Bryan H ^a   Duong, Timothy Q ^a,b,c,d  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^d SOUTHWEST NATIONAL PRIMATE RESEARCH CENTER   (United States)

Author keywords

CBF; CBV; CMRglc; CMRO2; high field fMRI; striatum

Indexed keywords

NEUROTRANSMITTER;

ANIMAL EXPERIMENT; ARTICLE; BOLD SIGNAL; BRAIN BLOOD FLOW; BRAIN BLOOD VOLUME; BRAIN CORTEX; BRAIN METABOLISM; BRAIN OXYGEN CONSUMPTION; CEREBRAL METABOLIC RATE OF OXYGEN; CONTROLLED STUDY; CORPUS STRIATUM; ELECTROSTIMULATION; FOREFOOT; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GLUCOSE BRAIN LEVEL; GLUCOSE INTAKE; HEMODYNAMIC MONITORING; MALE; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RAT; SOMATOSENSORY CORTEX; VASOCONSTRICTION;

ANIMALS; BLOOD VOLUME; CEREBRAL CORTEX; CORPUS STRIATUM; ELECTRIC STIMULATION; FLUORODEOXYGLUCOSE F18; FORELIMB; GLUCOSE; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; OXYGEN CONSUMPTION; PAIN; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; REGIONAL BLOOD FLOW;

EID: 79952193510     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2010.173     Document Type: Article

References (42)

1. Brown LL (1992) Somatotopic organization in rat striatum: evidence for a combinational map. Proc Natl Acad Sci USA 89:7403-7
2. Buxton RB (2010) Interpreting oxygenation-based neuro-imaging signals: the importance and the challenge of understanding brain oxygen metabolism. Front Neuroe-nerg 2:1-16
3. Chen CC, Shih YY, Mo KC, Yao NW, Lin ZJ, Huang CH, Shyu BC, Chang C (2009) Mapping dopaminergic denervation in Parkinson disease in vivo and in situ: the visualization of structural details by CBV-weighted fMRI. J Cereb Blood Flow Metab 29:S607-8
4. Choi JK, Chen YI, Hamel E, Jenkins BG (2006) Brain hemodynamic changes mediated by dopamine receptors: role of the cerebral microvasculature in dopamine-mediated neurovascular coupling. Neuro-Image 30:700-12
5. Choi JK, Mandeville JB, Chen YI, Grundt P, Sarkar SK, Newman AH, Jenkins BG (2010) Imaging brain regional and cortical laminar effects of selective D3 agonists and antagonists. Psychopharmacology 212:59-72
6. Chudler EH, Dong WK (1995) The role of the basal ganglia in nociception and pain. Pain 60:3-38
7. Davis TL, Kwong KK, Weisskoff RM, Rosen BR (1998) Calibrated functional MRI: mapping the dynamics of oxidative metabolism. Proc Natl Acad Sci USA 95:1834-9 (Pubitemid 28103480)
8. Dawson DR, Killackey HP (1987) The organization and mutability of the forepaw and hindpaw representations in the somatosensory cortex of the neonatal rat. J Comp Neurol 256:246-56 (Pubitemid 17016431)
9. Duong TQ, Silva AC, Lee SP, Kim SG (2000) Functional MRI of calcium-dependent synaptic activity: cross correlation with CBF and BOLD measurements. Magn Reson Med 43:383-92 (Pubitemid 30127525)
10. Graybiel AM (1990) Neurotransmitters and neuromodula-tors in the basal ganglia. Trends Neurosci 13:244-54
11. Grubb Jr RL, Raichle ME, Eichling JO, Ter-Pogossian MM (1974) The effects of changes in PaCO2 on cerebral blood volume, blood flow, and vascular mean transit time. Stroke 5:630-9
12. Harel N, Lee SP, Nagaoka T, Kim DS, Kim SG (2002) Origin of negative blood oxygenation level-dependent fMRI signals. J Cereb Blood Flow Metab 22:908-17 (Pubitemid 34831597)
13. Herscovitch P, Raichle ME (1985) What is the correct value for the brain-blood partition coefficient for water? J Cereb Blood Flow Metab 5:65-9 (Pubitemid 15146560)
14. Hillman EM, Devor A, Bouchard MB, Dunn AK, Krauss GW, Skoch J, Bacskai BJ, Dale AM, Boas DA (2007) Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulation. NeuroImage 35:89-104 (Pubitemid 46240938)
15. Hoge RD, Atkinson J, Gill B, Crelier GR, Marrett S, Pike GB (1999) Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: the deoxyhemoglobin dilution model. Magn Reson Med 42:849-63 (Pubitemid 29521474)
16. Keilholz SD, Silva AC, Raman M, Merkle H, Koretsky AP (2006) BOLD and CBV-weighted functional magnetic resonance imaging of the rat somatosensory system. Magn Reson Med 55:316-24 (Pubitemid 43238100)
17. Kennan RP, Scanley BE, Innis RB, Gore JC (1998) Physiological basis for BOLD MR signal changes due to neuronal stimulation: separation of blood volume and magnetic susceptibility effects. Magn Reson Med 40:840-6 (Pubitemid 28543835)
18. Kim T, Hendrich KS, Masamoto K, Kim SG (2007) Arterial versus total blood volume changes during neural activity-induced cerebral blood flow change: implication for BOLD fMRI. J Cereb Blood Flow Metab 27: 1235-47 (Pubitemid 46808710)
19. Krimer LS, Muly III EC, Williams GV, Goldman-Rakic PS (1998) Dopaminergic regulation of cerebral cortical microcirculation. Nat Neurosci 1:286-9
20. Lee SP, Duong TQ, Yang G, Iadecola C, Kim SG (2001) Relative changes of cerebral arterial and venous blood volumes during increased cerebral blood flow: implications for BOLD fMRI. Magn Reson Med 45: 791-800 (Pubitemid 32402021)
21. Liu ZM, Schmidt KF, Sicard KM, Duong TQ (2004) Imaging oxygen consumption in forepaw somatosensory stimulation in rats under isoflurane anesthesia. Magn Reson Med 52:277-85 (Pubitemid 39025271)
22. Lu H, Scholl CA, Zuo Y, Stein EA, Yang Y (2007) Quantifying the blood oxygenation level dependent effect in cerebral blood volume-weighted functional MRI at 9.4T. Magn Reson Med 58:616-21 (Pubitemid 350154974)
23. Mandeville JB, Marota JJ, Kosofsky BE, Keltner JR, Weissleder R, Rosen BR, Weisskoff RM (1998) Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn Reson Med 39:615-24 (Pubitemid 28150996)
24. Mao J, Mayer DJ, Price DD (1993) Patterns of increased brain activity indicative of pain in a rat model of peripheral mononeuropathy. J Neurosci 13:2689-702 (Pubitemid 23151783)
25. McGeorge AJ, Faull RL (1989) The organization of the projection from the cerebral cortex to the striatum in the rat. Neuroscience 29:503-37
26. Morrow TJ, Paulson PE, Danneman PJ, Casey KL (1998) Regional changes in forebrain activation during the early and late phase of formalin nociception: analysis using cerebral blood flow in the rat. Pain 75:355-65 (Pubitemid 28160147)
27. Pawela CP, Biswal BB, Hudetz AG, Li R, Jones SR, Cho YR, Matloub HS, Hyde JS (2010) Interhemispheric neuro-plasticity following limb deafferentation detected by resting-state functional connectivity magnetic resonance imaging (fcMRI) and functional magnetic resonance imaging (fMRI). NeuroImage 49:2467-78
28. Schridde U, Khubchandani M, Motelow JE, Sanganahalli BG, Hyder F, Blumenfeld H (2008) Negative BOLD with large increases in neuronal activity. Cereb Cortex 18:1814-27 (Pubitemid 352019902)
29. Shen Q, Ren H, Duong TQ (2008) CBF, BOLD, CBV, and CMRO(2) fMRI signal temporal dynamics at 500-msec resolution. J Magn Reson Imaging 27:599-606 (Pubitemid 351354746)
30. Shih YY, Chen YY, Chen JC, Chang C, Jaw FS (2007) ISPMER: Integrated System for Combined PET, MRI, and Electrophysiological Recording in Somatosensory Studies in Rats. Nucl Instrum Meth A 580:938-43 (Pubitemid 47379918)
31. Shih YY, Chen YY, Chen CC, Chen JC, Chang C, Jaw FS (2008a) Whole-brain functional magnetic resonance imaging mapping of acute nociceptive responses induced by formalin in rats using atlas registration-based event-related analysis. J Neurosci Res 86:1801-11 (Pubitemid 351859430)
32. Shih YY, Chiang YC, Chen JC, Huang CH, Chen YY, Liu RS, Chang C, Jaw FS (2008b) Brain nociceptive imaging in rats using (18)f-fluorodeoxyglucose small-animal positron emission tomography. Neuroscience 155:1221-6
33. Shih YY, Chen CC, Shyu BC, Lin ZJ, Chiang YC, Jaw FS, Chen YY, Chang C (2009) A new scenario for negative functional magnetic resonance imaging signals: endogenous neurotransmission. J Neurosci 29:3036-44
34. Shih YY, Chiang YC, Hsu YH, Jaw FS, Chen JC, Shyu BC, Duong TQ, Chang C (2010) Endogenous opioid-dopa-mine neurotransmission evokes sustained negative CBV-weighted fMRI responses. Proc Intl Soc Mag Reson Med (#710)
35. Shmuel A, Augath M, Oeltermann A, Logothetis NK (2006) Negative functional MRI response correlates with decreases in neuronal activity in monkey visual area V1. Nat Neurosci 9:569-77
36. Sicard KM, Shen Q, Brevard ME, Sullivan R, Ferris CF, King JA, Duong TQ (2003) Regional cerebral blood flow and BOLD responses in conscious and anesthetized rats under basal and hypercapnic conditions: implications for functional MRI studies. J Cereb Blood Flow Metab 23:472-81 (Pubitemid 36403029)
37. Sicard M, Duong TQ (2005) Effects of hypoxia, hyperoxia and hypercapnia on baseline and stimulus-evoked BOLD, CBF and CMRO2 in spontaneously breathing animals. Neuroimage 25:850-8 (Pubitemid 40461723)
38. Silva AC, Zhang W, Williams DS, Koretsky AP (1997) Estimation of water extraction fractions in rat brain using magnetic resonance measurement of perfusion with arterial spin labeling. Magn Reson Med 37:58-68 (Pubitemid 27008831)
39. Silva AC, Lee SP, Yang G, Iadecola C, Kim SG (1999) Simultaneous blood oxygenation level-dependent and cerebral blood flow functional magnetic resonance imaging during forepaw stimulation in the rat. J Cereb Blood Flow Metab 19:871-9 (Pubitemid 30173388)
40. Van CN, Verhoye M, Van der LA (2006) Stimulation of the rat somatosensory cortex at different frequencies and pulse widths. NMR Biomed 19:10-7 (Pubitemid 43250785)
41. Wichmann T, DeLong MR (1996) Functional and patho-physiological models of the basal ganglia. Curr Opin Neurobiol 6:751-8 (Pubitemid 27052915)
42. Zhao F, Zhao T, Zhou L, Wu Q, Hu X (2008) BOLD study of stimulation-induced neural activity and resting-state connectivity in medetomidine-sedated rat. NeuroImage 39:248-60 (Pubitemid 350102202)