Steroid requirements during radiotherapy for malignant gliomas

Journal of Neuro-Oncology

Volumn 100, Issue 1, 2010, Pages 89-94

  Marantidou, Athina ^a,b   Levy, Christine ^c   Duquesne, Alyette ^a,b   Ursu, Renata ^a,b   Bailon, Olivier ^a,b   Coman, Irene ^a,b   Belin, Catherine ^a,b   Carpentier, Antoine F ^a,b  

^a AVICENNE HOSPITAL   (France)

^b UNIVERSITÉ PARIS 13   (France)

^c Institut de Radiothérapie de Bobigny   (France)

Author keywords

Brain tumors; Glioma; Oedema; Radiotherapy; Steroids

Indexed keywords

PREDNISONE; TEMOZOLOMIDE;

ADJUVANT THERAPY; ADULT; ARTICLE; CANCER RADIOTHERAPY; CANCER SURGERY; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DOSE RESPONSE; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG INDICATION; DRUG MEGADOSE; DRUG USE; FEMALE; GLIOBLASTOMA; HUMAN; KARNOFSKY PERFORMANCE STATUS; MAJOR CLINICAL STUDY; MALE; NEUROSURGERY; OUTCOME ASSESSMENT; RADIATION DOSE; STEROID THERAPY; TREATMENT DURATION; TREATMENT RESPONSE;

AGE FACTORS; AGED; BRAIN NEOPLASMS; COMBINED MODALITY THERAPY; DOSE FRACTIONATION; FEMALE; GLIOMA; HUMANS; KARNOFSKY PERFORMANCE STATUS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROSPECTIVE STUDIES; RADIOTHERAPY; RETROSPECTIVE STUDIES; STEROIDS; TIME FACTORS;

EID: 79952193327     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-010-0142-8     Document Type: Article

References (23)

1. Behin A, Hoang-Xuan K, Carpentier AF, Delattre JY (2003) Primary brain tumors in adults. Lancet 361:323-331
2. Wen PY, Kesari S (2008) Malignant gliomas in adults. N Engl J Med 359:492-507
3. Stupp R, Mason WP, van den Bent MJ et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987-996 (Pubitemid 40349501)
4. Buatti J, Ryken TC, Smith MC et al (2008) Radiation therapy of pathologically confirmed newly diagnosed glioblastome in adults. J Neurooncol 89:313-337
5. Keime-Guibert F, Chinot O, Taillandier L et al (2007) Radiotherapy for glioblastoma for the elderly. N Engl J Med 356:1527-1535
6. Roa W, Brasher PMA, Bauman G et al (2004) Abbreviated course of radiation therapy in older patients with glioblastoma multiforme: a prospective randomised clinical trial. J Clin Oncol 22:1583-1588 (Pubitemid 41079795)
7. Posner JB(1995) Side effects of radiation therapy. In: Posner JB (ed) Neurologic complications of cancer. FA Davis, Philadelphia, pp 311-337
8. Li YQ, Guo P, Haimovitz-Friedman A, Reilly RM, Wong CS (2003) Endothelial apoptosis initiates acute blood-brain-barrier disruption after ionizing radiation. Cancer Res 63:5950-5956 (Pubitemid 37187496)
9. Faithfull S, Brada M (1998) Somnolence syndrome in adults following cranial irradiation for primary brain tumours. Clin Oncol (R Coll Radiol) 10:250-254 (Pubitemid 28454546)
10. Nightingale S, Schofield IS, Dawes PJ (1984) Visual, cortical somatosensory and brainstem auditory evoked potentials following incidental irradiation of the rhombencephalon. J Neurol Neurosurg Psychiatry 47:91-93 (Pubitemid 14154247)
11. Brandes AA, Tosoni A, Spagnolli F et al (2008) Disease progression or pseudoprogression after concomitant radiochemotherapy treatment: pitfalls in neurooncology. Neuro-Oncol 10:361-367
12. Brandsma D, Stalpers L, Taal W, Sminia P, van den Bent MJ (2008) Clinical features, mechanisms and management of pseudoprogression in malignant gliomas. Lancet Oncol 9:453-461 (Pubitemid 351597795)
13. Chamberlain MC, Glantz MJ, Chalmers L, Van Horn A, Sloan AE (2007) Early necrosis following concurrent temodar and radiotherapy in patients with glioblastoma. J Neurooncol 82:81-83
14. DeAngelis LM, Delattre JY, Posner JB (1989) Radiation-induced dementia in patients cured of brain metastases. Neurology 39:789-796 (Pubitemid 19150153)
15. Kofman S, Garvin JS, Nagamani D, Taylor SG 3rd (1957) Treatment of cerebral metastases from breast cancer with prednisolone. JAMA 163:1473-1476
16. French LA, Galicich JH (1964) The use of steroids for control of cerebral edema. Clin Neurosurg 10:212-223
17. Sturdza A, Millar BA, Bana N et al (2008) The use and toxicity of steroids in the management of patients with brain metastases. Support Care Cancer 16:1041-1048
18. Hempen C, Weiss E, Hess CF (2002) Dexamethasone treatment in patients with brain metastases and primary brain tumors: do the benefits outweigh the side-effects? Support Care Cancer 10:322-328
19. Vecht Ch J, Hovestadt A (1994) Dose-effect relationship of dexamethasone on Karnofsky performance in metastatic brain tumors. Neurol 44:675-680
20. Furnari FB, Fenton T, Bachoo RM et al (2007) Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev 21:2683-2710 (Pubitemid 350070717)
21. Walker MD, Strike TA, Sheline GE (1979) An analysis of dose-effect relationship in the radiotherapy of malignant gliomas. Int J Radiat Oncol Biol Phys 5:1725-1731 (Pubitemid 10187518)
22. Taal W, Brandsma D, de Bruin HG et al. (2007) The incidence of pseudoprogression in a cohort of malignant glioma patients treated with chemo-radiation with temozolomide. Proc Am Soc Clin Oncol 25: A2009. Abstract
23. Brandes AA, Tosoni A, Franceschi E, Sotti G et al (2009) Recurrence pattern after temozolomide concomitant with and adjuvant to radiotherapy in newly diagnosed patients with glioblastoma: correlation with MGMT promoter methylation status. J Clin Oncol 10:1275-1279