Modulation of embryonic mesenchymal progenitor cell differentiation via control over pure mechanical modulus in electrospun nanofibers

Acta Biomaterialia

Volumn 7, Issue 4, 2011, Pages 1516-1524

  Nam, Jin ^a   Johnson, Jed ^b   Lannutti, John J ^b   Agarwal, Sudha ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b Ohio State University   (United States)

Author keywords

Bone; Cartilage; Mechanical properties; Scaffold; Stem cell differentiation

Indexed keywords

BIOMECHANICS; CELL CULTURE; CELL ENGINEERING; ENZYME ACTIVITY; FIBERS; GENE EXPRESSION; PHOSPHATASES; SCAFFOLDS (BIOLOGY); SHELLS (STRUCTURES); STEM CELLS; STIFFNESS; SURFACE CHEMISTRY;

CORE SHELL; EMBRYONICS; GENES EXPRESSION; MESENCHYMAL PROGENITOR CELLS; MICROENVIRONMENTS; POLY(-CAPROLACTONE); POLY(ETHER SULFONE); POLYETHER SULFONE; STEM CELL DIFFERENTIATION; STEM-CELL;

CARTILAGE;

AGGRECAN; ALKALINE PHOSPHATASE; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN; NANOFIBER; OSTEOCALCIN; POLYETHERSULFONE; TRANSCRIPTION FACTOR SOX9;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL STRUCTURE; CHONDROGENESIS; ELECTROSPINNING; EMBRYONIC STEM CELL; ENZYME ACTIVITY; GENE EXPRESSION; GENE SEQUENCE; MESENCHYMAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; UPREGULATION;

EID: 79952193164     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2010.11.022     Document Type: Article

References (54)

1. I.H. Park, R. Zhao, J.A. West, A. Yabuuchi, H.G. Huo, and T.A. Ince Reprogramming of human somatic cells to pluripotency with defined factors Nature 451 2008 141 146
2. K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, and K. Tomoda Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872 (Pubitemid 350138099)
3. P. Bianco, N. Riminucci, S. Kuznetsov, and P.G. Robey Multipotential cells in the bone marrow stroma: regulation in the context of organ physiology Crit Rev Eukaryot Gene Expr 9 1999 159 173
4. D.J. Prockop Marrow stromal cells as stem cells for nonhematopoietic tissues Science 276 1997 71 74 (Pubitemid 27161245)
5. N. Sun, N.J. Panetta, D.M. Gupta, K.D. Wilson, A. Lee, and F. Jia Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells Proc Natl Acad Sci USA 106 2009 15720 15725
6. P.A. Zuk, M. Zhu, H. Mizuno, J. Huang, J.W. Futrell, and A.J. Katz Multilineage cells from human adipose tissue: implications for cell-based therapies Tissue Eng 7 2001 211 228 (Pubitemid 32295155)
7. C.J. Wilson, R.E. Clegg, D.I. Leavesley, and M.J. Pearcy Mediation of biomaterial-cell interactions by adsorbed proteins: a review Tissue Eng 11 2005 1 18 (Pubitemid 40515171)
8. B.S. Kim, J. Nikolovski, J. Bonadio, E. Smiley, and D.J. Mooney Engineered smooth muscle tissues: regulating cell phenotype with the scaffold Exp Cell Res 251 1999 318 328 (Pubitemid 29431869)
9. E. Ruoslahti, and J.C. Reed Anchorage dependence, integrins, and apoptosis Cell 77 1994 477 478 (Pubitemid 24153987)
10. I.I. Singer, S. Scott, D.W. Kawka, D.M. Kazazis, J. Gailit, and E. Ruoslahti Cell-surface distribution of fibronectin and vitronectin receptors depends on substrate composition and extracellular-matrix accumulation J Cell Biol 106 1988 2171 2182
11. A.J. Garcia, M.D. Vega, and D. Boettiger Modulation of cell proliferation and differentiation through fibronectin conformational changes Mol Biol Cell 9 1998 168A
12. A. Curtis, and C. Wilkinson Topographical control of cells Biomaterials 18 1997 1573 1583 (Pubitemid 28185057)
13. E.T. den Braber, J.E. de Ruijter, L.A. Ginsel, A.F. von Recum, and J.A. Jansen Quantitative analysis of fibroblast morphology on microgrooved surfaces with various groove and ridge dimensions Biomaterials 17 1996 2037 2044 (Pubitemid 26345638)
14. E.K.F. Yim, and K.W. Leong Significance of synthetic nanostructures in dictating cellular response Nanomedicine 1 2005 10 21 (Pubitemid 43963610)
15. M.J. Dalby, N. Gadegaard, R. Tare, A. Andar, M.O. Riehle, and P. Herzyk The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder Nat Mater 6 2007 997 1003 (Pubitemid 350210577)
16. A. Chaubey, K.J. Ross, R.M. Leadbetter, and K.J.L. Burg Surface patterning: tool to modulate stem cell differentiation in an adipose system J Biomed Mater Res B Appl Biomater 84 2008 70 78
17. N.S. Hwang, M.S. Kim, S. Sampattavanich, J.H. Baek, Z.J. Zhang, and J. Elisseeff Effects of three-dimensional culture and growth factors on the chondrogenic differentiation of murine embryonic stem cells Stem cells 24 2006 284 291 (Pubitemid 44464796)
18. H. Tanaka, C.L. Murphy, C. Murphy, M. Kimura, S. Kawai, and J.M. Polak Chondrogenic differentiation of murine embryonic stem cells: effects of culture conditions and dexamethasone J Cell Biochem 93 2004 454 462 (Pubitemid 44264181)
19. A. Matthews Jamil, E. Wnek Gary, G. Simpson David, and L. Bowlin Gary Electrospinning of collagen nanofibers Biomacromolecules 3 2002 232 238
20. M.Y. Li, M.J. Mondrinos, M.R. Gandhi, F.K. Ko, A.S. Weiss, and P.I. Lelkes Electrospun protein fibers as matrices for tissue engineering Biomaterials 26 2005 5999 6008 (Pubitemid 40805606)
21. L. Buttafoco, N.G. Kolkman, P. Engbers-Buijtenhuijs, A.A. Poot, P.J. Dijkstra, and I. Vermes Electrospinning of collagen and elastin for tissue engineering applications Biomaterials 27 2005 724 734
22. N. Bhattarai, D. Edmondson, O. Veiseh, F.A. Matsen, and M.Q. Zhang Electrospun chitosan-based nanofibers and their cellular compatibility Biomaterials 26 2005 6176 6184 (Pubitemid 40826986)
23. I.C. Um, D. Fang, B.S. Hsiao, A. Okamoto, and B. Chu Electro-spinning and electro-blowing of hyaluronic acid Biomacromolecules 5 2004 1428 1436 (Pubitemid 39089746)
24. M.-S. Khil, R. Bhattarai Shanta, H.-Y. Kim, S.-Z. Kim, and K.-H. Lee Novel fabricated matrix via electrospinning for tissue engineering J Biomed Mater Res B Appl Biomater 72 2005 117 124 (Pubitemid 40039617)
25. W.-J. Li, R. Tuli, X. Huang, P. Laquerriere, and R.S. Tuan Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold Biomaterials 26 2005 5158 5166 (Pubitemid 40387839)
26. W.J.W.-J. Li, R. Tuli, C. Okafor, A. Derfoul, K.G.K.G. Danielson, and D.J.D.J. Hall A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells Biomaterials 26 2005 599 609 (Pubitemid 38988302)
27. T.A. Telemeco, C. Ayres, G.L. Bowlin, G.E. Wnek, E.D. Boland, and N. Cohen Regulation of cellular infiltration into tissue engineering scaffolds composed of submicron diameter fibrils produced by electrospinning Acta Biomater 1 2005 377 385 (Pubitemid 43348774)
28. A. Bianco, E. Di Federico, I. Moscatelli, A. Camaioni, I. Armentano, and L. Campagnolo Electrospun poly(epsilon-caprolactone)/Ca-deficient hydroxyapatite nanohybrids: microstructure, mechanical properties and cell response by murine embryonic stem cells Mater Sci Eng C Mater Biol Appl 29 2009 2063 2071
29. Teh TKH, Goh JCH, Toh SL. Characterization of electrospun substrates for ligament regeneration using bone marrow stromal cells. In: Proceedings of the 13th international conference on biomedical engineering. Berlin, Heidelberg: Springer; 2009. p. 1488-91.
30. W.J. Li, J.A. Cooper, R.L. Mauck, and R.S. Tuan Fabrication and characterization of six electrospun poly(alpha-hydroxy ester)-based fibrous scaffolds for tissue engineering applications Acta Biomater 2 2006 377 385 (Pubitemid 43840927)
31. J. Nam, Y. Huang, S. Agarwal, and J. Lannutti Materials selection and residual solvent retention in biodegradable electrospun fibers J Appl Polym Sci 107 2008 1547 1554
32. J. Johnson, A. Ghosh, and J. Lannutti Microstructure-property relationships in a tissue-engineering scaffold J Appl Polym Sci 104 2007 2919 2927 (Pubitemid 46707281)
33. J. Gaumer, A. Prasad, D. Lee, and J. Lannutti Structure-function relationships and source-to-ground distance in electrospun polycaprolactone Acta Biomater 5 2009 1552 1561
34. S. Drilling, J. Gaumer, and J. Lannutti Fabrication of burst pressure competent vascular grafts via electrospinning: effects of microstructure J Biomed Mat Res A 88 2009 923 934
35. A.E. Denker, A.R. Haas, S.B. Nicoll, and R.S. Tuan Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures Differentiation 64 1999 67 76 (Pubitemid 29077834)
36. L. Zhao, G. Li, K.M. Chan, Y. Wang, and P.F. Tang Comparison of multipotent differentiation potentials of murine primary bone marrow stromal cells and mesenchymal stem cell line C3H10T1/2 Calcif Tissue Int 84 2009 56 64
37. J. Nam, B. Rath, T.J. Knobloch, J.J. Lannutti, and S. Agarwal Novel electrospun scaffolds for the molecular analysis of chondrocytes under dynamic compression Tissue Eng A 15 2009 513 523
38. K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method Methods 25 2001 402 408 (Pubitemid 34164012)
39. J.T. Dingle, P. Horsfield, H.B. Fell, and M.E.J. Barratt Breakdown of proteoclycan and collagen induced in pig articular-cartilage in organ-culature Ann Rheum Dis 34 1975 303 311
40. J. Nam, Y. Huang, S. Agarwal, and J. Lannutti Improved cellular infiltration in electrospun fiber via engineered porosity Tissue Eng 13 2007 2249 2257 (Pubitemid 47404440)
41. F. Sbrana, C. Sassoli, E. Meacci, D. Nosi, R. Squecco, and F. Paternostro Role for stress fiber contraction in surface tension development and stretch-activated channel regulation in C2C12 myoblasts Am J Physiol Cell Physiol 295 2008 C160 C172
42. H. Polzer, F. Haasters, W.C. Prall, M.M. Saller, E. Volkmer, and I. Drosse Quantification of fluorescence intensity of labeled human mesenchymal stem cells and cell counting of unlabeled cells in phase-contrast imaging: an open-source-based algorithm Tissue Eng Part C Methods 16 6 2010 1277 1285
43. D.M. Bell, K.K.H. Leung, S.C. Wheatley, L.J. Ng, S. Zhou, and K.W. Ling SOX9 directly regulates the type-II collagen gene Nat Genet 16 1997 174 178 (Pubitemid 27240616)
44. T.F. Day, X.Z. Guo, L. Garrett-Beal, and Y.Z. Yang Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis Dev Cell 8 2005 739 750 (Pubitemid 40585296)
45. D.E. Ingber, and I. Tensegrity Cell structure and hierarchical systems biology J Cell Sci 116 2003 1157 1173 (Pubitemid 36410656)
46. S.H. Crandall An Introduction to the Mechanics of Solids 1978 McGraw-Hill New York
47. J.L. Tan, J. Tien, D.M. Pirone, D.S. Gray, K. Bhadriraju, and C.S. Chen Cells lying on a bed of microneedles: an approach to isolate mechanical force Proc Natl Acad Sci USA 100 2003 1484 1489 (Pubitemid 36254472)
48. Z.L. Wang, Z.R. Dai, R.P. Gao, and J.L. Gole Measuring the Young's modulus of solid nanowires by in situ TEM J Electron Microsc 51 2002 S79 S85
49. J.E. Phillips, T.A. Petrie, F.P. Creighton, and A.J. Garcia Human mesenchymal stem cell differentiation on self-assembled monolayers presenting different surface chemistries Acta Biomater 6 2010 12 20
50. R.F. Loeser Integrins and cell signaling in chondrocytes Biorheology 39 2002 119 124 (Pubitemid 34626055)
51. H. Pommerenke, C. Schmidt, F. Durr, B. Nebe, F. Luthen, and P. Muller The mode of mechanical integrin stressing controls intracellular signaling in osteoblasts J Bone Miner Res 17 2002 603 611 (Pubitemid 34246635)
52. H.M. Powell, D.A. Kniss, and J.J. Lannutti Nanotopographic control of cytoskeletal organization Langmuir 22 2006 5087 5094 (Pubitemid 44012075)
53. J.P. Rodriguez, M. Gonzalez, S. Rios, and V. Cambiazo Cytoskeletal organization of human mesenchymal stem cells (MSC) changes during their osteogenic differentiation J Cell Biochem 93 2004 721 731 (Pubitemid 44264168)
54. E. Langelier, R. Suetterlin, C.D. Hoemann, U. Aebi, and M.D. Buschmann The chondrocyte cytoskeleton in mature articular cartilage: structure and distribution of actin, tubulin, and vimentin filaments J Histochem Cytochem 48 2000 1307 1320