Protein disulfide isomerase isomerizes non-native disulfide bonds in human proinsulin independent of its peptide-binding activity

Protein Science

Volumn 20, Issue 3, 2011, Pages 588-596

  Winter, Jeannette ^a   Gleiter, Stefan ^b   Klappa, Peter ^c   Lilie, Hauke ^d  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b ROCHE DIAGNOSTICS GMBH   (Germany)

^c UNIVERSITY OF KENT   (United Kingdom)

^d MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Chaperone; Disulfide bond formation; Disulfide isomerization; Folding intermediate; Oxidative protein folding

Indexed keywords

CHAPERONE; MUTANT PROTEIN; PROINSULIN; PROTEIN DISULFIDE ISOMERASE;

ARTICLE; DISULFIDE BOND; ISOMERIZATION; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION;

DISULFIDES; HUMANS; ISOMERISM; MOLECULAR CHAPERONES; MUTATION; OXIDATION-REDUCTION; PEPTIDES; PROINSULIN; PROTEIN DENATURATION; PROTEIN DISULFIDE-ISOMERASES; PROTEIN FOLDING;

EID: 79952179046     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.592     Document Type: Article

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