메뉴 건너뛰기




Volumn 5, Issue 1, 2011, Pages 9-16

Indacaterol: Pharmacologic profile, efficacy and safety in the treatment of adults with COPD

Author keywords

bronchodilator treatment; chronic obstructive pulmonary disease; indacaterol; LABA; long acting agonist; 2 adrenoceptor agonist

Indexed keywords

BREEZHALER; INDACATEROL; ONBREZ; UNCLASSIFIED DRUG;

EID: 79952174578     PISSN: 17476348     EISSN: 17476356     Source Type: Journal    
DOI: 10.1586/ers.10.91     Document Type: Article
Times cited : (6)

References (49)
  • 1
    • 4344675455 scopus 로고    scopus 로고
    • Pathophysiology of airflow limitation in chronic obstructive pulmonary disease
    • DOI 10.1016/S0140-6736(04)16900-6, PII S0140673604169006
    • Hogg JC. Pathophysiology of airflow limitation in chronic obstructive pulmonary disease. Lancet 364(9435), 709-721 (2004). (Pubitemid 39140629)
    • (2004) Lancet , vol.364 , Issue.9435 , pp. 709-721
    • Hogg, J.C.1
  • 2
    • 69249222635 scopus 로고    scopus 로고
    • Inhaled corticosteroids as combination therapy with b-adrenergic agonists in airways disease: Present and future
    • Chung KF, Caramori G, Adcock IM. Inhaled corticosteroids as combination therapy with b-adrenergic agonists in airways disease: present and future. Eur. J. Clin. Pharmacol. 65(9), 853-871 (2009).
    • (2009) Eur. J. Clin. Pharmacol. , vol.65 , Issue.9 , pp. 853-871
    • Chung, K.F.1    Caramori, G.2    Adcock, I.M.3
  • 3
    • 57349099228 scopus 로고    scopus 로고
    • Emerging pharmacotherapies for COPD
    • Barnes PJ. Emerging pharmacotherapies for COPD. Chest 134(6), 1278-1286 (2008).
    • (2008) Chest , vol.134 , Issue.6 , pp. 1278-1286
    • Barnes, P.J.1
  • 4
    • 69149095164 scopus 로고    scopus 로고
    • Phosphodiesterase-4 inhibition in COPD
    • OByrne PM, Gauvreau G. Phosphodiesterase-4 inhibition in COPD. Lancet 374(9691), 665-667 (2009).
    • (2009) Lancet , vol.374 , Issue.9691 , pp. 665-667
    • Obyrne, P.M.1    Gauvreau, G.2
  • 5
    • 0024323574 scopus 로고
    • 2-adrenergic receptor subtypes revealed by molecular cloning
    • Frielle T, Caron MG, Lefkowitz RJ. Properties of the b 1- and b 2-adrenergic receptor subtypes revealed by molecular cloning. Clin. Chem. 35(5), 721-725 (1989). (Pubitemid 19162062)
    • (1989) Clinical Chemistry , vol.35 , Issue.5 , pp. 721-725
    • Frielle, T.1    Caron, M.G.2    Lefkowitz, R.J.3
  • 7
    • 42949152368 scopus 로고    scopus 로고
    • Bronchodilator responsiveness in patients with COPD
    • Tashkin DP, Celli B, Decramer M et al. Bronchodilator responsiveness in patients with COPD. Eur. Respir. J. 31(4), 742-750 (2008).
    • (2008) Eur. Respir. J. , vol.31 , Issue.4 , pp. 742-750
    • Tashkin, D.P.1    Celli, B.2    Decramer, M.3
  • 8
    • 0037036199 scopus 로고    scopus 로고
    • β-Adrenoceptor agonists and asthma - 100 Years of development
    • DOI 10.1016/S0014-2999(02)01728-4, PII S0014299902017284
    • Waldeck B. b-adrenoceptor agonists and asthma - 100 years of development. Eur. J. Pharmacol. 445(1-2), 1-12 (2002). (Pubitemid 34632676)
    • (2002) European Journal of Pharmacology , vol.445 , Issue.1-2 , pp. 1-12
    • Waldeck, B.1
  • 9
    • 52949146750 scopus 로고    scopus 로고
    • Novel long-acting bronchodilators for COPD and asthma
    • Cazzola M, Matera MG. Novel long-acting bronchodilators for COPD and asthma. Br. J. Pharmacol. 155(3), 291-299 (2008).
    • (2008) Br. J. Pharmacol. , vol.155 , Issue.3 , pp. 291-299
    • Cazzola, M.1    Matera, M.G.2
  • 10
    • 51249091910 scopus 로고    scopus 로고
    • Patient adherence in COPD
    • Bourbeau J, Bartlett SJ. Patient adherence in COPD. Thorax 63(9), 831-838 (2008).
    • (2008) Thorax , vol.63 , Issue.9 , pp. 831-838
    • Bourbeau, J.1    Bartlett, S.J.2
  • 11
    • 77953028976 scopus 로고    scopus 로고
    • The short, the long and the ultra-long: Why duration of bronchodilator action matters in chronic obstructive pulmonary disease
    • Beeh KM, Beier J. The short, the long and the ultra-long: why duration of bronchodilator action matters in chronic obstructive pulmonary disease. Adv. Ther. 27(3), 150-159 (2010).
    • (2010) Adv. Ther. , vol.27 , Issue.3 , pp. 150-159
    • Beeh, K.M.1    Beier, J.2
  • 12
    • 70350455492 scopus 로고    scopus 로고
    • Defining disease modification in chronic obstructive pulmonary disease
    • Halpin DM, Tashkin DP. Defining disease modification in chronic obstructive pulmonary disease. COPD 6(3), 211-225 (2009).
    • (2009) COPD , vol.6 , Issue.3 , pp. 211-225
    • Halpin, D.M.1    Tashkin, D.P.2
  • 13
    • 0034055236 scopus 로고    scopus 로고
    • A randomised controlled comparison of tiotropium and ipratropium in the treatment of chronic obstructive pulmonary disease
    • DOI 10.1136/thorax.55.4.289
    • van Noord JA, Bantje TA, Eland ME, Korducki L, Cornelissen PJ. A randomised controlled comparison of tiotropium nd ipratropium in the treatment of chronic obstructive pulmonary disease. The Dutch Tiotropium Study Group. Thorax 55(4), 289-294 (2000). (Pubitemid 30248798)
    • (2000) Thorax , vol.55 , Issue.4 , pp. 289-294
    • Van Noord, J.A.1    Bantje Th., A.2    Eland, M.E.3    Korducki, L.4    Cornelissen, P.J.G.5
  • 15
    • 0033748430 scopus 로고    scopus 로고
    • The spirometric efficacy of once-daily dosing with tiotropium in stable COPD: A 13-week multicenter trial
    • The US Tiotropium Study Group
    • Casaburi R, Briggs DD Jr, Donohue JF, Serby CW, Menjoge SS, Witek TJ Jr. The spirometric efficacy of once-daily dosing with tiotropium in stable COPD: a 13-week multicenter trial. The US Tiotropium Study Group. Chest 118(5), 1294-1302 (2000).
    • (2000) Chest , vol.118 , Issue.5 , pp. 1294-1302
    • Casaburi, R.1    Briggs Jr., D.D.2    Donohue, J.F.3    Serby, C.W.4    Menjoge, S.S.5    Witek Jr., T.J.6
  • 17
    • 0034871011 scopus 로고    scopus 로고
    • A systematic review of the associations between dose regimens and medication compliance
    • DOI 10.1016/S0149-2918(01)80109-0
    • Claxton AJ, Cramer J, Pierce C. A systematic review of the associations between dose regimens and medication compliance. Clin. Ther. 23(8), 1296-1310 (2001). (Pubitemid 32804122)
    • (2001) Clinical Therapeutics , vol.23 , Issue.8 , pp. 1296-1310
    • Claxton, A.J.1    Cramer, J.2    Pierce, C.3
  • 18
    • 77953707790 scopus 로고    scopus 로고
    • Efficacy of a new once-daily long-acting inhaled b2-agonist indacaterol versus twice-daily formoterol in COPD
    • Dahl R, Chung KF, Buhl R et al. Efficacy of a new once-daily long-acting inhaled b2-agonist indacaterol versus twice-daily formoterol in COPD. Thorax 65(6), 473-479 (2010).
    • (2010) Thorax , vol.65 , Issue.6 , pp. 473-479
    • Dahl, R.1    Chung, K.F.2    Buhl, R.3
  • 19
    • 44749085093 scopus 로고    scopus 로고
    • A dose-ranging study of indacaterol in obstructive airways disease, with a tiotropium comparison
    • Rennard S, Bantje T, Centanni S et al. A dose-ranging study of indacaterol in obstructive airways disease, with a tiotropium comparison. Resp. Med. 102(7), 1033-1044 (2008).
    • (2008) Resp. Med. , vol.102 , Issue.7 , pp. 1033-1044
    • Rennard, S.1    Bantje, T.2    Centanni, S.3
  • 21
    • 64249171524 scopus 로고    scopus 로고
    • 24-hour bronchodilator efficacy of single doses of indacaterol in subjects with COPD: Comparison with placebo and formoterol
    • Bauwens O, Ninane V, Van de Maele B et al. 24-hour bronchodilator efficacy of single doses of indacaterol in subjects with COPD: comparison with placebo and formoterol. Curr. Med. Res. Opin. 25(2), 463-470 (2009).
    • (2009) Curr. Med. Res. Opin. , vol.25 , Issue.2 , pp. 463-470
    • Bauwens, O.1    Ninane, V.2    Van De Maele, B.3
  • 22
    • 77958141697 scopus 로고    scopus 로고
    • Characteristics of a capsule based dry powder inhaler for the delivery of indacaterol
    • Pavkov R, Mueller S, Fiebich K et al. Characteristics of a capsule based dry powder inhaler for the delivery of indacaterol. Curr. Med. Res. Opin. 26(11), 2527-2533 (2010).
    • (2010) Curr. Med. Res. Opin. , vol.26 , Issue.11 , pp. 2527-2533
    • Pavkov, R.1    Mueller, S.2    Fiebich, K.3
  • 23
    • 33645882522 scopus 로고    scopus 로고
    • In vitro and in vivo pharmacological characterization of 5-[(R)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-8- hydroxy-1H-quinolin- 2-one (indacaterol), a novel inhaled b(2) adrenoceptor agonist with a 24-h duration of action
    • Battram C, Charlton SJ, Cuenoud B et al. In vitro and in vivo pharmacological characterization of 5-[(R)-2-(5,6-diethyl-indan-2-ylamino)-1- hydroxy-ethyl]-8- hydroxy-1H-quinolin-2-one (indacaterol), a novel inhaled b(2) adrenoceptor agonist with a 24-h duration of action. J. Pharmacol. Exp. Ther. 317(2), 762-770 (2006).
    • (2006) J. Pharmacol. Exp. Ther. , vol.317 , Issue.2 , pp. 762-770
    • Battram, C.1    Charlton, S.J.2    Cuenoud, B.3
  • 25
    • 37348999950 scopus 로고    scopus 로고
    • 2 adrenoceptor agonist, on small airways in human and rat precision-cut lung slices
    • DOI 10.1124/jpet.107.129296
    • Sturton RG, Trifilieff A, Nicholson AG, Barnes PJ. Pharmacological characterization of indacaterol, a novel once daily inhaled 2 adrenoceptor agonist, on small airways in human and rat precision-cut lung slices. J. Pharmacol. Exp. Ther. 324(1), 270-275 (2008). (Pubitemid 350294169)
    • (2008) Journal of Pharmacology and Experimental Therapeutics , vol.324 , Issue.1 , pp. 270-275
    • Sturton, R.G.1    Trifilieff, A.2    Nicholson, A.G.3    Barnes, P.J.4
  • 26
    • 69249208553 scopus 로고    scopus 로고
    • Pharmacogenetic characterization of indacaterol, a novel b 2-adrenoceptor agonist
    • Sayers I, Hawley J, Stewart CE et al. Pharmacogenetic characterization of indacaterol, a novel b 2-adrenoceptor agonist. Br. J. Pharmacol. 158(1), 277-286 (2009).
    • (2009) Br. J. Pharmacol. , vol.158 , Issue.1 , pp. 277-286
    • Sayers, I.1    Hawley, J.2    Stewart, C.E.3
  • 27
  • 28
    • 70349337022 scopus 로고    scopus 로고
    • 24-hour bronchodilator efficacy of single doses of indacaterol in patients with persistent asthma: Comparison with placebo and formoterol
    • LaForce C, Korenblat P, Osborne P, Dong F, Higgins M. 24-hour bronchodilator efficacy of single doses of indacaterol in patients with persistent asthma: comparison with placebo and formoterol. Curr. Med. Res. Opin. 25(10), 2353-2359 (2009).
    • (2009) Curr. Med. Res. Opin. , vol.25 , Issue.10 , pp. 2353-2359
    • Laforce, C.1    Korenblat, P.2    Osborne, P.3    Dong, F.4    Higgins, M.5
  • 30
    • 77952054496 scopus 로고    scopus 로고
    • The identification of indacaterol as an ultralong-acting inhaled b2-adrenoceptor agonist
    • Baur F, Beattie D, Beer D et al. The identification of indacaterol as an ultralong-acting inhaled b2-adrenoceptor agonist. J. Med. Chem. 53(9), 3675-3684 (2010).
    • (2010) J. Med. Chem. , vol.53 , Issue.9 , pp. 3675-3684
    • Baur, F.1    Beattie, D.2    Beer, D.3
  • 31
    • 70449518003 scopus 로고    scopus 로고
    • Lipid membrane interactions of indacaterol and salmeterol: Do they influence their pharmacological properties?
    • Lombardi D, Cuenoud B, Kramer SD. Lipid membrane interactions of indacaterol and salmeterol: do they influence their pharmacological properties? Eur. J. Pharm. Sci. 38(5), 533-547 (2009).
    • (2009) Eur. J. Pharm. Sci. , vol.38 , Issue.5 , pp. 533-547
    • Lombardi, D.1    Cuenoud, B.2    Kramer, S.D.3
  • 32
    • 55249126351 scopus 로고    scopus 로고
    • A cell-based assay to assess the persistence of action of agonists acting at recombinant human b(2) adrenoceptors
    • Summerhill S, Stroud T, Nagendra R, Perros-Huguet C, Trevethick M. A cell-based assay to assess the persistence of action of agonists acting at recombinant human b(2) adrenoceptors. J. Pharmacol. Toxicol. Methods 58(3), 189-197 (2008).
    • (2008) J. Pharmacol. Toxicol. Methods , vol.58 , Issue.3 , pp. 189-197
    • Summerhill, S.1    Stroud, T.2    Nagendra, R.3    Perros-Huguet, C.4    Trevethick, M.5
  • 33
    • 77951221549 scopus 로고    scopus 로고
    • Efficacy and safety of indacaterol 150 microg once-daily in COPD: A double-blind, randomised, 12-week study
    • Feldman G, Siler T, Prasad N et al. Efficacy and safety of indacaterol 150 microg once-daily in COPD: a double-blind, randomised, 12-week study. BMC Pulm. Med. 10, 11 (2010).
    • (2010) BMC Pulm. Med. , vol.10 , pp. 11
    • Feldman, G.1    Siler, T.2    Prasad, N.3
  • 35
    • 33645851329 scopus 로고    scopus 로고
    • Safety and tolerability of multiple-dose indacaterol, a novel b2-agonist, in patients with mild asthma [abstract]
    • Tarral A, Fauchoux N, Knight H. Safety and tolerability of multiple-dose indacaterol, a novel b2-agonist, in patients with mild asthma [abstract]. Eur. Respir. J. 26, 253S (2005).
    • (2005) Eur. Respir. J. , vol.26
    • Tarral, A.1    Fauchoux, N.2    Knight, H.3
  • 36
    • 33646840570 scopus 로고    scopus 로고
    • Single-dose indacaterol, a novel 24-h b2-agonist, is well tolerated in patients with mild asthma [abstract]
    • Duvauchelle T, Elharrar B, Knight H. Single-dose indacaterol, a novel 24-h b2-agonist, is well tolerated in patients with mild asthma [abstract]. Eur. Respir. J. 26, 253S (2005).
    • (2005) Eur. Respir. J. , vol.26
    • Duvauchelle, T.1    Elharrar, B.2    Knight, H.3
  • 37
    • 77950340063 scopus 로고    scopus 로고
    • Integrating indacaterol dose selection in a clinical study in COPD using an adaptive seamless design
    • Barnes PJ, Pocock SJ, Magnussen H et al. Integrating indacaterol dose selection in a clinical study in COPD using an adaptive seamless design. Pulm. Pharmacol. Ther. 23(3), 165-171 (2010).
    • (2010) Pulm. Pharmacol. Ther. , vol.23 , Issue.3 , pp. 165-171
    • Barnes, P.J.1    Pocock, S.J.2    Magnussen, H.3
  • 39
    • 77954800883 scopus 로고    scopus 로고
    • Once-daily bronchodilators for chronic obstructive pulmonary disease: Indacaterol versus tiotropium
    • Donohue JF, Fogarty C, Lotvall J et al. Once-daily bronchodilators for chronic obstructive pulmonary disease: indacaterol versus tiotropium. Am. J. Respir. Crit. Care Med. 182(2), 155-162 (2010).
    • (2010) Am. J. Respir. Crit. Care Med. , vol.182 , Issue.2 , pp. 155-162
    • Donohue, J.F.1    Fogarty, C.2    Lotvall, J.3
  • 40
    • 79953026850 scopus 로고    scopus 로고
    • Once-daily indacaterol vs twice-daily salmeterol for COPD: A placebo-controlled comparison
    • DOI: 10.1183/09031936.00045810 Epub ahead of print
    • Kornmann O, Dahl R, Centanni S et al. Once-daily indacaterol vs twice-daily salmeterol for COPD: a placebo-controlled comparison. Eur. Respir. J. DOI: 10.1183/09031936.00045810 (2010) (Epub ahead of print).
    • (2010) Eur. Respir. J.
    • Kornmann, O.1    Dahl, R.2    Centanni, S.3
  • 41
    • 74049163417 scopus 로고    scopus 로고
    • Effect of indacaterol maleate on dynamic lung hyperinflation in patients with COPD
    • Beeh KM, Khindri S, Eeg M, Drollman AF. Effect of indacaterol maleate on dynamic lung hyperinflation in patients with COPD. Eur. Respir. J. 34, 4357 (2009).
    • (2009) Eur. Respir. J. , vol.34 , pp. 4357
    • Beeh, K.M.1    Khindri, S.2    Eeg, M.3    Drollman, A.F.4
  • 43
    • 73449115661 scopus 로고    scopus 로고
    • Indacaterol, a novel inhaled, once-daily, long-acting b2-agonist for the treatment of obstructive airways diseases. Erratum appears in
    • Beeh KM, Beier J. Indacaterol, a novel inhaled, once-daily, long-acting b2-agonist for the treatment of obstructive airways diseases. Erratum appears in Adv.Ther. 2009 6(8): 812
    • (2009) Adv.Ther. , vol.6 , Issue.8 , pp. 812
    • Beeh, K.M.1    Beier, J.2
  • 44
    • 79952149514 scopus 로고    scopus 로고
    • Note: Dosage error in article text
    • Note: Dosage error in article text. Adv.Ther. 26(7), 691-699 (2009).
    • (2009) Adv.Ther. , vol.26 , Issue.7 , pp. 691-699
  • 45
    • 37749048011 scopus 로고    scopus 로고
    • Efficacy and safety of single therapeutic and supratherapeutic doses of indacaterol versus salmeterol and salbutamol in patients with asthma
    • Brookman LJ, Knowles LJ, Barbier M, Elharrar B, Fuhr R, Pascoe S. Efficacy and safety of single therapeutic and supratherapeutic doses of indacaterol versus salmeterol and salbutamol in patients with asthma. Curr. Med. Res. Opin. 23(12), 3113-3122 (2007).
    • (2007) Curr. Med. Res. Opin. , vol.23 , Issue.12 , pp. 3113-3122
    • Brookman, L.J.1    Knowles, L.J.2    Barbier, M.3    Elharrar, B.4    Fuhr, R.5    Pascoe, S.6
  • 46
    • 57749189082 scopus 로고    scopus 로고
    • Efficacy and safety of indacaterol, a new 24-hour b2-agonist, in patients with asthma: A dose-ranging study
    • Kanniess F, Boulet LP, Pierzchala W, Cameron R, Owen R, Higgins M. Efficacy and safety of indacaterol, a new 24-hour b2-agonist, in patients with asthma: a dose-ranging study. J. Asthma 45(10), 887-892 (2008).
    • (2008) J. Asthma , vol.45 , Issue.10 , pp. 887-892
    • Kanniess, F.1    Boulet, L.P.2    Pierzchala, W.3    Cameron, R.4    Owen, R.5    Higgins, M.6
  • 48
    • 48949103222 scopus 로고    scopus 로고
    • Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: Results from the TORCH study
    • Celli BR, Thomas NE, Anderson JA et al. Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH study. Am. J. Respir. Crit. Care Med. 178(4), 332-338 (2008).
    • (2008) Am. J. Respir. Crit. Care Med. , vol.178 , Issue.4 , pp. 332-338
    • Celli, B.R.1    Thomas, N.E.2    Anderson, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.