Regional rescue of spinocerebellar ataxia type 1 phenotypes by 14-3-3ε haploinsufficiency in mice underscores complex pathogenicity in neurodegeneration

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 5, 2011, Pages 2142-2147

  Jafar Nejad, Paymaan ^a   Ward, Christopher S ^a   Richman, Ronald ^a   Orr, Harry T ^c   Zoghbi, Huda Y ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TEXAS CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Ataxin1 like; Capicua; Purkinje; RBM17; Ywhae

Indexed keywords

ATAXIN 1; PROTEIN 14 3 3; PROTEIN 14 3 3 EPSILON; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN REGION; BRAIN STEM; CEREBELLAR ATAXIA; COMPLEX FORMATION; CONTROLLED STUDY; FEMALE; HAPLOTYPE; HETEROZYGOSITY; MALE; MOUSE; NERVE DEGENERATION; NEWBORN; NONHUMAN; NULL ALLELE; PATHOGENICITY; PHENOTYPE; PREMATURITY; PRIORITY JOURNAL; PROTEIN STABILITY; RESPIRATORY FAILURE;

14-3-3 PROTEINS; ALLELES; ANIMALS; BRAIN; CELL LINE; HAPLOINSUFFICIENCY; HUMANS; MICE; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHENOTYPE; SPINOCEREBELLAR ATAXIAS;

MUS;

EID: 79952168998     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018748108     Document Type: Article

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